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The map label for this gene is lppA

Identifier: 148823738

GI number: 148823738

Start: 2879786

End: 2880445

Strand: Direct

Name: lppA

Synonym: TBFG_12563

Alternate gene names: 148823738

Gene position: 2879786-2880445 (Clockwise)

Preceding gene: 148823737

Following gene: 148823739

Centisome position: 65.09

GC content: 61.06

Gene sequence:

>660_bases
GTGATCGCACCACAACCGATTTCCCGAACGCTCCCGCGGTGGCAGCGCATCGTCGCGCTGACCATGATCGGCATATCAAC
CGCCCTGATAGGTGGCTGCACCATGGATCACAACCCTGACACATCACGGCGCCTGACCGGCGAGCAGAAGATCCAGCTCA
TCGACAGCATGCGCAACAAGGGCTCCTACGAGGCCGCCCGGGAGCGCCTAACCGCCACCGCCCGGATCATCGCCGACCGC
GTCAGTGCGGCCATCCCGGGCCAAACCTGGAAATTCGACGACGATCCCAACATACAACAGTCTGACCGAAACGGAGCACT
GTGCGACAAGCTCACCGCGGATATCGCGCGGCGGCCGATCGCCAACAGCGTAATGTTCGGCGCCACGTTCTCGGCCGAGG
ACTTCAAGATTGCCGCCAATATCGTGCGGGAGGAAGCCGCCAAGTACGGTGCGACCACCGAGTCGTCGCTATTTAACGAA
TCGGCCAAGCGCGACTACGACGTGCAGGGCAACGGCTACGAATTCCGACTCCTGCAAATCAAATTCGCCACACTTAACAT
CACCGGCGATTGTTTTCTGTTGCAGAAGGTGCTCGACCTGCCGGCCGGACAACTCCCCCCGGAACCACCCATCTGGCCAA
CGACCTCGACGCCACATTGA

Upstream 100 bases:

>100_bases
CGCAATACGGCCAAGACCCGCTGCAACGGATGACCGGCTACAACCTGGCGACCATCCTGCTCAACCGGCCCGATCTGGCG
GTGCGCGAAAGCCCACAGCA

Downstream 100 bases:

>100_bases
TCGCACCACAACCGATTCCCCGAACGCTCCCACGGTGGCAGCGCATCGTCGCGCTGACCATGATCGGCATATCAACCGCC
CTGATAGGTGGCTGCACAAT

Product: lipoprotein lppA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MIAPQPISRTLPRWQRIVALTMIGISTALIGGCTMDHNPDTSRRLTGEQKIQLIDSMRNKGSYEAARERLTATARIIADR
VSAAIPGQTWKFDDDPNIQQSDRNGALCDKLTADIARRPIANSVMFGATFSAEDFKIAANIVREEAAKYGATTESSLFNE
SAKRDYDVQGNGYEFRLLQIKFATLNITGDCFLLQKVLDLPAGQLPPEPPIWPTTSTPH

Sequences:

>Translated_219_residues
MIAPQPISRTLPRWQRIVALTMIGISTALIGGCTMDHNPDTSRRLTGEQKIQLIDSMRNKGSYEAARERLTATARIIADR
VSAAIPGQTWKFDDDPNIQQSDRNGALCDKLTADIARRPIANSVMFGATFSAEDFKIAANIVREEAAKYGATTESSLFNE
SAKRDYDVQGNGYEFRLLQIKFATLNITGDCFLLQKVLDLPAGQLPPEPPIWPTTSTPH
>Mature_219_residues
MIAPQPISRTLPRWQRIVALTMIGISTALIGGCTMDHNPDTSRRLTGEQKIQLIDSMRNKGSYEAARERLTATARIIADR
VSAAIPGQTWKFDDDPNIQQSDRNGALCDKLTADIARRPIANSVMFGATFSAEDFKIAANIVREEAAKYGATTESSLFNE
SAKRDYDVQGNGYEFRLLQIKFATLNITGDCFLLQKVLDLPAGQLPPEPPIWPTTSTPH

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mycobacteriales lppA/lppB family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LPPA_MYCTU (P95010)

Other databases:

- EMBL:   BX842580
- EMBL:   AE000516
- PIR:   C70659
- RefSeq:   NP_217059.1
- RefSeq:   NP_337115.1
- PDB:   2V7S
- PDBsum:   2V7S
- EnsemblBacteria:   EBMYCT00000003116
- EnsemblBacteria:   EBMYCT00000070574
- GeneID:   888052
- GeneID:   925697
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT2618
- KEGG:   mtu:Rv2543
- TIGR:   MT2618
- TubercuList:   Rv2543
- GeneTree:   EBGT00050000018104
- HOGENOM:   HBG565270
- ProtClustDB:   CLSK791914

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 24181; Mature: 24181

Theoretical pI: Translated: 7.35; Mature: 7.35

Prosite motif: PS51257 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIAPQPISRTLPRWQRIVALTMIGISTALIGGCTMDHNPDTSRRLTGEQKIQLIDSMRNK
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCHHHHHHHHHHHCC
GSYEAARERLTATARIIADRVSAAIPGQTWKFDDDPNIQQSDRNGALCDKLTADIARRPI
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCC
ANSVMFGATFSAEDFKIAANIVREEAAKYGATTESSLFNESAKRDYDVQGNGYEFRLLQI
CCCEEECCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCEEEEEEEE
KFATLNITGDCFLLQKVLDLPAGQLPPEPPIWPTTSTPH
EEEEEEECCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MIAPQPISRTLPRWQRIVALTMIGISTALIGGCTMDHNPDTSRRLTGEQKIQLIDSMRNK
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCHHHHHHHHHHHCC
GSYEAARERLTATARIIADRVSAAIPGQTWKFDDDPNIQQSDRNGALCDKLTADIARRPI
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCC
ANSVMFGATFSAEDFKIAANIVREEAAKYGATTESSLFNESAKRDYDVQGNGYEFRLLQI
CCCEEECCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCEEEEEEEE
KFATLNITGDCFLLQKVLDLPAGQLPPEPPIWPTTSTPH
EEEEEEECCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036