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The map label for this gene is rbsK [H]

Identifier: 148823638

GI number: 148823638

Start: 2747904

End: 2748818

Strand: Direct

Name: rbsK [H]

Synonym: TBFG_12463

Alternate gene names: 148823638

Gene position: 2747904-2748818 (Clockwise)

Preceding gene: 148823632

Following gene: 148823639

Centisome position: 62.11

GC content: 68.85

Gene sequence:

>915_bases
ATGGCAAACGCCAGTGAGACTAACGTCGGCCCCATGGCGCCCCGGGTGTGCGTGGTAGGCAGCGTGAACATGGACCTGAC
GTTCGTGGTGGACGCGCTTCCGCGCCCCGGCGAGACGGTGCTTGCGGCGTCGTTGACCCGAACGCCAGGCGGGAAGGGCG
CCAACCAGGCGGTGGCCGCAGCGCGCGCAGGCGCGCAGGTACAGTTCTCCGGTGCATTCGGCGACGATCCAGCCGCCGCC
CAGCTGCGGGCCCACCTGCGCGCCAACGCCGTTGGACTGGACAGGACCGTCACGGTGCCCGGACCGAGCGGGACGGCGAT
TATCGTGGTCGATGCCAGCGCCGAGAACACCGTGCTGGTGGCGCCGGGTGCCAATGCACATCTGACTCCGGTACCCTCGG
CCGTCGCCAACTGCGATGTACTGTTGACCCAGTTGGAGATTCCTGTTGCAACCGCGCTGGCAGCCGCGCGGGCAGCCCAG
TCGGCCGATGCGGTTGTCATGGTCAACGCCTCCCCAGCCGGCCAGGATCGAAGCTCCTTGCAGGACTTGGCCGCTATCGC
CGACGTGGTGATCGCCAACGAGCATGAGGCAAACGACTGGCCGTCGCCACCAACACATTTCGTGATCACCCTGGGTGTGC
GCGGTGCCCGGTACGTCGGCGCGGACGGGGTGTTCGAGGTACCCGCCCCAACGGTAACGCCAGTGGATACCGCCGGCGCC
GGCGACGTATTTGCCGGGGTCCTTGCTGCGAATTGGCCGCGCAACCCAGGTTCGCCGGCCGAGCGACTGCGCGCATTGCG
GCGGGCCTGCGCTGCGGGTGCGCTGGCAACTTTGGTGTCCGGTGCCGGCGACTGCGCACCGGCCGCCGCCGCGATCGATG
CGGCCCTGCGAGCCAACCGCCACAACGGTTCATGA

Upstream 100 bases:

>100_bases
ATCCGCAAGCATGTTCGAATACTGGGACGCGCCACCGACAGGACACCCACTGATACCCTTGGGACAAAAGTGACACAAGT
GATTTCAGCCAACAGCAAGC

Downstream 100 bases:

>100_bases
CCACTGCTACGCACCGAAGGAGACCCGCTGATGCGAACGACCACCGCGGCCGACTTAGCGCTGGCACTCTTCGCGGTTTT
CAGTGTGGTCGGATTCGGCT

Product: ribokinase rbsK

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 303

Protein sequence:

>304_residues
MANASETNVGPMAPRVCVVGSVNMDLTFVVDALPRPGETVLAASLTRTPGGKGANQAVAAARAGAQVQFSGAFGDDPAAA
QLRAHLRANAVGLDRTVTVPGPSGTAIIVVDASAENTVLVAPGANAHLTPVPSAVANCDVLLTQLEIPVATALAAARAAQ
SADAVVMVNASPAGQDRSSLQDLAAIADVVIANEHEANDWPSPPTHFVITLGVRGARYVGADGVFEVPAPTVTPVDTAGA
GDVFAGVLAANWPRNPGSPAERLRALRRACAAGALATLVSGAGDCAPAAAAIDAALRANRHNGS

Sequences:

>Translated_304_residues
MANASETNVGPMAPRVCVVGSVNMDLTFVVDALPRPGETVLAASLTRTPGGKGANQAVAAARAGAQVQFSGAFGDDPAAA
QLRAHLRANAVGLDRTVTVPGPSGTAIIVVDASAENTVLVAPGANAHLTPVPSAVANCDVLLTQLEIPVATALAAARAAQ
SADAVVMVNASPAGQDRSSLQDLAAIADVVIANEHEANDWPSPPTHFVITLGVRGARYVGADGVFEVPAPTVTPVDTAGA
GDVFAGVLAANWPRNPGSPAERLRALRRACAAGALATLVSGAGDCAPAAAAIDAALRANRHNGS
>Mature_303_residues
ANASETNVGPMAPRVCVVGSVNMDLTFVVDALPRPGETVLAASLTRTPGGKGANQAVAAARAGAQVQFSGAFGDDPAAAQ
LRAHLRANAVGLDRTVTVPGPSGTAIIVVDASAENTVLVAPGANAHLTPVPSAVANCDVLLTQLEIPVATALAAARAAQS
ADAVVMVNASPAGQDRSSLQDLAAIADVVIANEHEANDWPSPPTHFVITLGVRGARYVGADGVFEVPAPTVTPVDTAGAG
DVFAGVLAANWPRNPGSPAERLRALRRACAAGALATLVSGAGDCAPAAAAIDAALRANRHNGS

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=271, Percent_Identity=29.520295202952, Blast_Score=92, Evalue=5e-19,
Organism=Escherichia coli, GI1790193, Length=259, Percent_Identity=35.1351351351351, Blast_Score=117, Evalue=7e-28,
Organism=Escherichia coli, GI87082343, Length=253, Percent_Identity=30.4347826086957, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17532905, Length=268, Percent_Identity=31.7164179104478, Blast_Score=101, Evalue=5e-22,
Organism=Drosophila melanogaster, GI20128807, Length=307, Percent_Identity=33.8762214983713, Blast_Score=107, Evalue=8e-24,
Organism=Drosophila melanogaster, GI24583886, Length=290, Percent_Identity=28.2758620689655, Blast_Score=87, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 30252; Mature: 30121

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANASETNVGPMAPRVCVVGSVNMDLTFVVDALPRPGETVLAASLTRTPGGKGANQAVAA
CCCCCCCCCCCCCCCEEEEECCCCCEEEEEECCCCCCCEEEEEEEECCCCCCCCHHHHHH
ARAGAQVQFSGAFGDDPAAAQLRAHLRANAVGLDRTVTVPGPSGTAIIVVDASAENTVLV
HHCCCEEEECCCCCCCHHHHHHHHHHHHCEECCCCEEECCCCCCCEEEEEECCCCCEEEE
APGANAHLTPVPSAVANCDVLLTQLEIPVATALAAARAAQSADAVVMVNASPAGQDRSSL
ECCCCCCCCCCCHHHHHHEEEEEECCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHH
QDLAAIADVVIANEHEANDWPSPPTHFVITLGVRGARYVGADGVFEVPAPTVTPVDTAGA
HHHHHHHHHHEECCCCCCCCCCCCCEEEEEEECCCCEEECCCCEEECCCCCCCCCCCCCC
GDVFAGVLAANWPRNPGSPAERLRALRRACAAGALATLVSGAGDCAPAAAAIDAALRANR
CHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCC
HNGS
CCCC
>Mature Secondary Structure 
ANASETNVGPMAPRVCVVGSVNMDLTFVVDALPRPGETVLAASLTRTPGGKGANQAVAA
CCCCCCCCCCCCCCEEEEECCCCCEEEEEECCCCCCCEEEEEEEECCCCCCCCHHHHHH
ARAGAQVQFSGAFGDDPAAAQLRAHLRANAVGLDRTVTVPGPSGTAIIVVDASAENTVLV
HHCCCEEEECCCCCCCHHHHHHHHHHHHCEECCCCEEECCCCCCCEEEEEECCCCCEEEE
APGANAHLTPVPSAVANCDVLLTQLEIPVATALAAARAAQSADAVVMVNASPAGQDRSSL
ECCCCCCCCCCCHHHHHHEEEEEECCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHH
QDLAAIADVVIANEHEANDWPSPPTHFVITLGVRGARYVGADGVFEVPAPTVTPVDTAGA
HHHHHHHHHHEECCCCCCCCCCCCCEEEEEEECCCCEEECCCCEEECCCCCCCCCCCCCC
GDVFAGVLAANWPRNPGSPAERLRALRRACAAGALATLVSGAGDCAPAAAAIDAALRANR
CHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCC
HNGS
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7921236; 9353933; 9384377 [H]