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The map label for this gene is hemN [H]

Identifier: 148823590

GI number: 148823590

Start: 2695310

End: 2696482

Strand: Reverse

Name: hemN [H]

Synonym: TBFG_12413

Alternate gene names: 148823590

Gene position: 2696482-2695310 (Counterclockwise)

Preceding gene: 148823591

Following gene: 148823588

Centisome position: 60.95

GC content: 68.97

Gene sequence:

>1173_bases
ATGGTATTTCGGCAGGCACCAGTTGAGCTGCCCGGCCTGGCGCCCATGCCCGGACAACCGTTCGGGGTCTACCTGCACGT
CCCGTTCTGCCTGACCCGTTGCGGGTACTGCGACTTCAATACCTACACCCCGGCCCAGCTGGGTGGCGTCAGCCCGGACC
GTTGGCTGCTGGCGCTGCGGGCGGAGCTCGAACTGGCGGCCGCCAAGCTGGACGCACCGACGGTGCATACCGTGTATGTG
GGTGGCGGGACGCCATCGCTGCTCGGGGGGGAGCGCCTGGCCACGTTGCTGGACATGGTGCGGGACCACTTTGTGCTGGC
GCCCGACGCCGAAGTCAGCACCGAGGCCAACCCCGAGTCGACGTGGCCGGAGTTCTTCGCCACGATCCGCGCGGCCGGTT
ACACGCGGGTGTCGCTCGGCATGCAGTCGGTGGCCCCGAGGGTGCTGGCAACCTTGGACCGGGTGCACTCGCCGGGCCGG
GCGGCGGCCGCGGCCACCGAGGCGATAGCGGAGGGCTTCACACACGTCAACCTCGACCTGATCTATGGAACCCCGGGGGA
GTCCGACGACGACCTGGTGCGCTCAGTGGACGCCGCGGTGCAGGCCGGTGTGGATCATGTGTCCGCGTATGCCTTGGTCG
TCGAGCACGGCACGGCACTGGCTCGCCGGGTTCGGCGTGGTGAGCTGGCCGCGCCCGATGACGACGTGCTGGCGCATCGC
TACGAGTTGGTCGATGCTCGGCTGTCGGCGGCCGGGTTTGCCTGGTACGAGGTGTCCAATTGGTGTCGACCGGGCGGCGA
GTGCCGGCACAACCTGGGTTATTGGGACGGTGGCCAGTGGTGGGGCGCAGGTCCGGGCGCGCACGGCTACATTGGCGTGA
CACGCTGGTGGAATGTCAAGCACCCCAACACTTACGCCGAGATACTGGCCGGGGCGACGTTGCCGGTAGCGGGCTTCGAG
CAGCTGGGCGCCGACGCTTTGCACACCGAAGACGTGTTGCTGAAGGTCCGGCTGCGCCAGGGGCTACCGCTCGCCCGGCT
AGGGGCTGCCGAACGGGAACGTGCCGAGGCGGTGTTGGCCGACGGATTGCTGGACTACCACGGCGACCGACTGGTCCTCA
CCGGCCGGGGGCGATTGCTGGCCGACGCGGTGGTGCGCACTCTGCTGGGCTAA

Upstream 100 bases:

>100_bases
GGCCGAGACTGGAGGTTGTTCGGGGAGCAGGGACGATTGAGGTGTGCCTGCGTTACATTGCTGGCCACCCTAGCTGGTAC
GCGCTATGCGATGATTTGGC

Downstream 100 bases:

>100_bases
CCGATCGAAGCCCCGGTGGCAGGGAACCATTGCCCGACGATGCGGGCGATCTCGATGTACAGCGGGATCCCGATCGTGAC
GTTGTAGGAGAACGTCAAAC

Product: coproporphyrinogen III oxidase

Products: NA

Alternate protein names: Coprogen oxidase; Coproporphyrinogenase [H]

Number of amino acids: Translated: 390; Mature: 390

Protein sequence:

>390_residues
MVFRQAPVELPGLAPMPGQPFGVYLHVPFCLTRCGYCDFNTYTPAQLGGVSPDRWLLALRAELELAAAKLDAPTVHTVYV
GGGTPSLLGGERLATLLDMVRDHFVLAPDAEVSTEANPESTWPEFFATIRAAGYTRVSLGMQSVAPRVLATLDRVHSPGR
AAAAATEAIAEGFTHVNLDLIYGTPGESDDDLVRSVDAAVQAGVDHVSAYALVVEHGTALARRVRRGELAAPDDDVLAHR
YELVDARLSAAGFAWYEVSNWCRPGGECRHNLGYWDGGQWWGAGPGAHGYIGVTRWWNVKHPNTYAEILAGATLPVAGFE
QLGADALHTEDVLLKVRLRQGLPLARLGAAERERAEAVLADGLLDYHGDRLVLTGRGRLLADAVVRTLLG

Sequences:

>Translated_390_residues
MVFRQAPVELPGLAPMPGQPFGVYLHVPFCLTRCGYCDFNTYTPAQLGGVSPDRWLLALRAELELAAAKLDAPTVHTVYV
GGGTPSLLGGERLATLLDMVRDHFVLAPDAEVSTEANPESTWPEFFATIRAAGYTRVSLGMQSVAPRVLATLDRVHSPGR
AAAAATEAIAEGFTHVNLDLIYGTPGESDDDLVRSVDAAVQAGVDHVSAYALVVEHGTALARRVRRGELAAPDDDVLAHR
YELVDARLSAAGFAWYEVSNWCRPGGECRHNLGYWDGGQWWGAGPGAHGYIGVTRWWNVKHPNTYAEILAGATLPVAGFE
QLGADALHTEDVLLKVRLRQGLPLARLGAAERERAEAVLADGLLDYHGDRLVLTGRGRLLADAVVRTLLG
>Mature_390_residues
MVFRQAPVELPGLAPMPGQPFGVYLHVPFCLTRCGYCDFNTYTPAQLGGVSPDRWLLALRAELELAAAKLDAPTVHTVYV
GGGTPSLLGGERLATLLDMVRDHFVLAPDAEVSTEANPESTWPEFFATIRAAGYTRVSLGMQSVAPRVLATLDRVHSPGR
AAAAATEAIAEGFTHVNLDLIYGTPGESDDDLVRSVDAAVQAGVDHVSAYALVVEHGTALARRVRRGELAAPDDDVLAHR
YELVDARLSAAGFAWYEVSNWCRPGGECRHNLGYWDGGQWWGAGPGAHGYIGVTRWWNVKHPNTYAEILAGATLPVAGFE
QLGADALHTEDVLLKVRLRQGLPLARLGAAERERAEAVLADGLLDYHGDRLVLTGRGRLLADAVVRTLLG

Specific function: Anaerobic transformation of coproporphyrinogen-III into protoporphyrinogen-IX [H]

COG id: COG0635

COG function: function code H; Coproporphyrinogen III oxidase and related Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anaerobic coproporphyrinogen-III oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922911, Length=286, Percent_Identity=38.1118881118881, Blast_Score=166, Evalue=2e-41,
Organism=Escherichia coli, GI1789325, Length=382, Percent_Identity=33.2460732984293, Blast_Score=198, Evalue=6e-52,
Organism=Escherichia coli, GI87082341, Length=313, Percent_Identity=26.1980830670927, Blast_Score=117, Evalue=9e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR004559
- InterPro:   IPR010723
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06969 HemN_C; PF04055 Radical_SAM [H]

EC number: =1.3.99.22 [H]

Molecular weight: Translated: 41941; Mature: 41941

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVFRQAPVELPGLAPMPGQPFGVYLHVPFCLTRCGYCDFNTYTPAQLGGVSPDRWLLALR
CCCCCCCCCCCCCCCCCCCCEEEEEECHHHHHHCCCCCCCCCCCHHHCCCCHHHHHHHHH
AELELAAAKLDAPTVHTVYVGGGTPSLLGGERLATLLDMVRDHFVLAPDAEVSTEANPES
HHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCEEECCCCCCCCCCCCCC
TWPEFFATIRAAGYTRVSLGMQSVAPRVLATLDRVHSPGRAAAAATEAIAEGFTHVNLDL
CHHHHHHHHHHCCCEEEHHCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEEEE
IYGTPGESDDDLVRSVDAAVQAGVDHVSAYALVVEHGTALARRVRRGELAAPDDDVLAHR
EECCCCCCHHHHHHHHHHHHHHCHHHHHHHHHEEHHHHHHHHHHHCCCCCCCCHHHHHHH
YELVDARLSAAGFAWYEVSNWCRPGGECRHNLGYWDGGQWWGAGPGAHGYIGVTRWWNVK
HHHHHHHHHHCCEEEEEHHHHCCCCHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEEECCC
HPNTYAEILAGATLPVAGFEQLGADALHTEDVLLKVRLRQGLPLARLGAAERERAEAVLA
CCCHHHHHHHCCCCCCCCHHHHCCCCCCHHHHHHEEHHHCCCCHHHHCCHHHHHHHHHHH
DGLLDYHGDRLVLTGRGRLLADAVVRTLLG
HHHHHHCCCEEEEECCCCHHHHHHHHHHCC
>Mature Secondary Structure
MVFRQAPVELPGLAPMPGQPFGVYLHVPFCLTRCGYCDFNTYTPAQLGGVSPDRWLLALR
CCCCCCCCCCCCCCCCCCCCEEEEEECHHHHHHCCCCCCCCCCCHHHCCCCHHHHHHHHH
AELELAAAKLDAPTVHTVYVGGGTPSLLGGERLATLLDMVRDHFVLAPDAEVSTEANPES
HHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCEEECCCCCCCCCCCCCC
TWPEFFATIRAAGYTRVSLGMQSVAPRVLATLDRVHSPGRAAAAATEAIAEGFTHVNLDL
CHHHHHHHHHHCCCEEEHHCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEEEE
IYGTPGESDDDLVRSVDAAVQAGVDHVSAYALVVEHGTALARRVRRGELAAPDDDVLAHR
EECCCCCCHHHHHHHHHHHHHHCHHHHHHHHHEEHHHHHHHHHHHCCCCCCCCHHHHHHH
YELVDARLSAAGFAWYEVSNWCRPGGECRHNLGYWDGGQWWGAGPGAHGYIGVTRWWNVK
HHHHHHHHHHCCEEEEEHHHHCCCCHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEEECCC
HPNTYAEILAGATLPVAGFEQLGADALHTEDVLLKVRLRQGLPLARLGAAERERAEAVLA
CCCHHHHHHHCCCCCCCCHHHHCCCCCCHHHHHHEEHHHCCCCHHHHCCHHHHHHHHHHH
DGLLDYHGDRLVLTGRGRLLADAVVRTLLG
HHHHHHCCCEEEEECCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]