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The map label for this gene is dhbF [H]

Identifier: 148823582

GI number: 148823582

Start: 2675362

End: 2680557

Strand: Reverse

Name: dhbF [H]

Synonym: TBFG_12405

Alternate gene names: 148823582

Gene position: 2680557-2675362 (Counterclockwise)

Preceding gene: 148823583

Following gene: 148823581

Centisome position: 60.59

GC content: 66.47

Gene sequence:

>5196_bases
GTGACTAATACCGCCGACATCGGCGCCCGCCTCGACGAGGCCCGATTGGAGCTGCTGCGTCGCAGGCTCGCCGACCGCGG
CCTGTCCTCGGCTGCGCAGGACATTGGCCCGCACACTGACGATCGGCTCTCCGACGGCCAGGCCCGGATGTGGTTCGTGC
AGATGGCCGACCCCAGCGGTGCGTTACTCAACATCTGTGTGTCCTACCGCATCACCGGTGACATCGATCTGGCCAGGTTG
CGCGACGCAGTCAACGCCGTCGCCCGTCGCCATCGGATACTGCGTACCACCTACCCTGTCGGCGACGACGGAGTCGCCCA
GCCGACCGTGCACGCGGATCTTCGCCCCGGCTGGACACAATACGACCTGACGGACCTGTCCCAACGCGCCCAGCGGCTGC
GCCTGGAGGTGTTGGCTCAGCGCGAATTCTGCGCTCCCTTCGAGCTTTCCCGCGACGCGCCATTGCGAATCACGGTGGTG
CGCACGGCTGCCGACGAACACGTGCTGCTGTTGGTGGCCCACCACATCGCCTGGGATGATGGTTCGTGGCGGGTGTTCTT
CACCGATCTCACCCAGGCGTACTCGCGAGCTGACCTAGGGGCCGATCTGGGGCCAGAACACCGTCCGTCGGCCGCATCCG
GACCCGACACTACCGAGGCCGACCTCAACTATTGGCGCGCGATCATGGCCGATCCGCCAGAGCCGCTGGAACTTCCCGGC
CCAGCCGGAACGTGTGTGCCGACCAGTTGGCGTGCCGCGCGCGCCACGTTGCGGCTGCCCGCCGACACCGCTGCGCGGGT
GGCCACGATGGCGAAGAACACCGGTTGCACTCCCTACATGGTGCTGCTGGCCGCGTTCGGTGCCCTGGTGCATCGCTACA
CCCACAGTGACGACTTCCTCGTGGCGGCTCCGGTGCTCAACCGTGGCGCCGGAACCGAAGATGCCATCGGCTATTTCGGC
AACACGGTAGCGATGCGGCTGCGACCGCAATCGGCGATGAGTTTCCGGGAGTTGCTGACCGCCACCCGCGACATCGCCAG
CGGGGCGTTCGCACACCAACGGATCAACCTCGACCGCGTGGTAAGGGAACTGAACCCCGATCGCCGGCACGGTGCCGAGC
GCATGACCCGGGTCAGCTTCGGTTTCCGGGAGCCCGACGGCGGCGGATTCAACCCGCCAGGCATCGAGTGCGAGCGCTAC
GACCTGCGCAGCAACATCACGCAGCTGCCGTTGGGCTTCATGGTCGAATTCGACCGCGCGGGTGTGCTGGTCGAGGCCGA
ACACCTGGTGGAGATCCTGGAACCCGCCCTGGCCAAGCAGATGCTTCGACACTTCGGTGTGCTGCTCGACAATGCGCTGG
CCGCCCCCGACAACACGTTGTCGGGGCTGGCGCTGATGGATGAGCGCGACGCCGCCAGGCTGCGCGAGGTGTCGCGCGGC
GAGCGGTTCGATACCCCTGTCAAAACCCTCGTGGACCTGGTGAACGAGCAGACCACGCGGACTCCCGACGCCACCGCCGT
GGTGTATGAGGGCCAACACTTCACCTACCACGACCTCAATGAGGCGTCGAACCGGTTGGGGCACTGGCTGATCGAGCAGG
GGATAGGCAGCGAAGACCGGGTCGCGGTACTTCTTGACAAATCGCCGGACCTGATCGTCACGGCCTTGGGGGTGGTCAAG
TCCGGGGCGGTGTATGTGCCCGTGGATCCCAGCTACCCGCAAGACCGGCTGGATTTCATCCTCGCCGACTGCGACGCGAA
ACTGGTGCTGCGCACGCCAGTACGTGAGCTGGCCGGATACCGCAGCGACGACCCCACCGACGCCGATCGAATCCGGCCGC
TACGGCCAGACAACACGGCCTATCTCATCTACACGTCCGGTACCACCGGATTGCCCAAAGGTGTCGCGGTGCCACACCGC
CCCGTCGCCGAGTACTTCGTCTGGTTCAAGGGCGAATACGACGTCGACGACACCGACCGGCTACTGCAGGTCGCCTCACC
CAGCTTCGACGTCTCGATCGCCGAGATCTTCGGCACGCTGGCCTGTGGCGCGCGGATGGTGATACCACGCCCCGGGGGAC
TCACCGACATTGGATATCTCACCGCCCTGTTGCGCGACGAGGGCATCACGGCAATGCATTTCGTGCCGTCCCTACTCGGG
CTGTTCCTGTCGCTGCCGGGTGTGAGCCAGTGGCGGACGTTGCAGCGGGTACCCATCGGCGGGGAGCCGCTACCCGGTGA
GGTGGCCGACAAGTTCCACGCGACATTCGATGCGCTGCTGCACAACTTCTACGGTCCAACCGAAACCGTGATCAACGCCA
GCCGGTTTAAAGTGGTGGGCCCACAGGGCACCCGCATCGTGCCCATCGGCCGGCCCAAGATCAACACCACCATGCACCTG
CTCGACGATTCGTTGCAGCCGGTGCCGACCGGTGTGATCGGCGAGATCTATATTGGAGGGACGCATGTCGCATACGGATA
CCATCGCCGCGCCGGGCTGACCGCGGAGCGATTCGTTGCCGACCCGTTTAATCCCGGTTCCCGCATGTACCGGTCCGGGG
ATCTGGCGCGCCGCAATGCTGACGGTGACATCGAGTTCGTGGGCCGTGCCGACGAGCAGGTCAAGATTCGCGGATTCCGA
ATCGAACTCGGTGACGTAGCAGCGGCCATCGCGGTCGACCCTACGGTCGGGCAGGCCGTTGTGGTGGTTAGCGACCTGCC
GCGGCTGGGCAAGAGTCTGGTGGGCTACGTGACACCCGCCGCGGGCGGCGACGGACCCGCCGATGTCGGCGTCGATCTCG
ACCGCATCCGCGCCCGGGTGGCCGCGGCACTGCCTGAATATATGCTGCCCGCGGCCTATGTTGTGCTGGATGAGATTCCG
ATCACCGCGCATGGCAAAATCGACCGCGCCGCGCTGCCGGAACCGCAGATCGCGTCGGACACCGAGTTCCGCGCGCCGCA
GACCGCCACCGAGCGGCGCCTTGCCCAACTGTTCGGTGAGCTGCTCGGCCGCGACCGAGTGGGTGCTGACGACTCGTTCT
TCGACCTCGGCGGTCACTCGCTGCTGGCAACCAAACTCGTTGCGGCCGTGCGCAACGCGTTCGGCGTCGATGTCGGTGTG
CGGGAGATCTTCGAATTCGCCACGGTGACCGCGTTGGCCGGACACATCGATACGTTGGATTCGGATTCGGCGAGGCCGCG
GCTGACCCGGGTGGATCATGACGGGCCAGTGCGATTGTCGTCGTCTCAAATGCGTAGCTGGTTCAACTATCGCTTCGACG
GGCCCAACGCCGTCAACAACATTCCCTTCGCCGCGGCATTGCATGGGCCCTGCGACACCAACGCGTTCGCGGCGGCCATC
ACCGATGTGGTGGCACGCCACGAGATCCTGCGCACCGTCTACCGCGAGATCGGCGGCGTGCCACACCAGATCATCCAGCC
GCCCGCCGAGGTGCCGGTGCGGTGCGCCGCCGGGTCCGACGCCGCGTGGCTGCGAGCCGAACTGAACAACGAGCGAGGTT
ACGTTTTCGACCTGGAAACCGACTGGCCGATCCGGGCGGCGCTGCTGAGCACGCCGGAGCAGACCGTGTTGTCGCTGGTG
GTGCATCACATCGCCGGCGACCACTGGTCGGCTGGGGTGTTGTTCACCGATCTGCTGACCGCATACCGGGCCCGCAGCAC
CGGACAACGGCCGTCGTGGGCACCGCTGCCGGTGCAGTACGCCGACTACAGCGTGTGGCAGTCGGCGCTACTCGACGACG
GTGCGGGCATCGTCGGTCCGCAACGCGACTACTGGATCCGCCAGCTGGGGGGCCTGGCAGGCGAAACCGGTCTGCGCCCG
GACTTCCCGCGCCCGGCCCTGCTCAGCGGTGCCGGTGACGCGGTCGAATTTCGTCTCGGCGCCGCGATCCGCGACAAATT
GGCTGCCGTGAGCCGAGACCTCGGTGTCACCGAGTTCATGCTGCTACAGGCCGCCGTCGCGGTGGTGTTACACAAGGCCG
GCGGCGGGGTAGACGTCCCCATCGGCGCCCCGGTGGCCGGTCGCAGCGAGGCCAACCTGGACCAGCTCATCGGGTTCTTC
ATCAACATCGTGGTGTTGCGCAACGACCTGCGCGGGAACCCCACGCTGCGCGAGGTGCTGCAGCGCACCAGGCAGATGGC
GCTGGCAGCGTATGCACATCAGGACCTGCCGTTCGACCAGGTGGTGGAGGCGGTCAACCCCCAGCGGTCGCTGTCCCGCA
ATCCGTTGTTCGACATTGTTGTGCACGTTCGCGAACAAATGCCGCAAGACCACGTCATCGACACCGGGCCCGACGGTGAC
ACCACGTTGCGCGTGCTGGAGCCGACATTCGATGCCGCGCAAGCCGATCTATCGGTCAACTTCTTCGCCTGCGGCGACGA
GTACCGCGGCCACGTCATCTACCGCACCGAGTTGTATGAGCGCGCCACCGCACAACGCTTCGCCGACTGGCTAGTCCGTG
TCGTCGAGGCGTTCGCCGACCGTCCGGACCAACCGCTGCGCGAGGTCGAGATGGTCAGCGCGCAAGCCAGACGGCGCATT
TTGGACCGGTCCAATGCGGGCGCCGGAACGGCCCGGGTGTACCTGCTTGACGACGCACTTAAGCCCGTTCCGGTAGGCGT
GGTGGGTGACGTTTATTACGGTGGCGGTCCCGCCGTCGGTGCCCGGTTGGCCCGGCCATCGGAGACCGCGACCCGATTCG
TTGCCGATCCGTTCGCCGCGCAACCGGGTTCTCGGCTCTACCGCAACGGCGAGCGCGGAGTGTGGAAGGCCGACGGCCAA
CTGGAGCTGCTGGCCGAAATCGAACGGCTGCCAACGGCGCAGGCGGCACCGGTGCCGGCCGAGCCCGCCGACACCGAAAC
CGAGCGCGCGCTGGCTGCCATCCTCGCCGACGTGCTCGAGGTGGGGGAGGTCGGACGCTACGACGACTTCTTCAACCTCG
GCGGCGACAGCATCCTCGCGACTCAGGTGGCTGCCCGGGCTCGAGATGGCGGGATACCGCTGACCGCGCGGATGGTTTTC
GAGCATCCCGTTTTGTGTGAGCTCGCCGCCGCGGTCGACGCCAAGCCTCACGTCGAGGCCGAGCCGGACGACAAGCATCA
CGCGCCGATGAGCACATCAGGGCTTTCCCCAGACGAACTGTCGGCCCTGACCGCGTCATGGGACCAGTGGCCGTGA

Upstream 100 bases:

>100_bases
CTGGCCACGCTCATGGGCGACATCACCGGTGATGGACTTGTCGCGAAACTCGAAGATGCCGACGAGCGCTCACACACCGC
ACAGAAAGTGGACATTTCGC

Downstream 100 bases:

>100_bases
CGCGAGCCGACGCGCGGGGCGCCATCGACGATGTGATGGCGCTCAGCCCATTGCAACAGGGACTGTTTTCTAGGGCGACA
CTGGTCGCCGCGGAGTCCGG

Product: peptide synthetase mbtE

Products: pyrophosphate; AMP; enterobactin; pyrophosphate; L-Seryl-AMP [C]

Alternate protein names: NA

Number of amino acids: Translated: 1731; Mature: 1730

Protein sequence:

>1731_residues
MTNTADIGARLDEARLELLRRRLADRGLSSAAQDIGPHTDDRLSDGQARMWFVQMADPSGALLNICVSYRITGDIDLARL
RDAVNAVARRHRILRTTYPVGDDGVAQPTVHADLRPGWTQYDLTDLSQRAQRLRLEVLAQREFCAPFELSRDAPLRITVV
RTAADEHVLLLVAHHIAWDDGSWRVFFTDLTQAYSRADLGADLGPEHRPSAASGPDTTEADLNYWRAIMADPPEPLELPG
PAGTCVPTSWRAARATLRLPADTAARVATMAKNTGCTPYMVLLAAFGALVHRYTHSDDFLVAAPVLNRGAGTEDAIGYFG
NTVAMRLRPQSAMSFRELLTATRDIASGAFAHQRINLDRVVRELNPDRRHGAERMTRVSFGFREPDGGGFNPPGIECERY
DLRSNITQLPLGFMVEFDRAGVLVEAEHLVEILEPALAKQMLRHFGVLLDNALAAPDNTLSGLALMDERDAARLREVSRG
ERFDTPVKTLVDLVNEQTTRTPDATAVVYEGQHFTYHDLNEASNRLGHWLIEQGIGSEDRVAVLLDKSPDLIVTALGVVK
SGAVYVPVDPSYPQDRLDFILADCDAKLVLRTPVRELAGYRSDDPTDADRIRPLRPDNTAYLIYTSGTTGLPKGVAVPHR
PVAEYFVWFKGEYDVDDTDRLLQVASPSFDVSIAEIFGTLACGARMVIPRPGGLTDIGYLTALLRDEGITAMHFVPSLLG
LFLSLPGVSQWRTLQRVPIGGEPLPGEVADKFHATFDALLHNFYGPTETVINASRFKVVGPQGTRIVPIGRPKINTTMHL
LDDSLQPVPTGVIGEIYIGGTHVAYGYHRRAGLTAERFVADPFNPGSRMYRSGDLARRNADGDIEFVGRADEQVKIRGFR
IELGDVAAAIAVDPTVGQAVVVVSDLPRLGKSLVGYVTPAAGGDGPADVGVDLDRIRARVAAALPEYMLPAAYVVLDEIP
ITAHGKIDRAALPEPQIASDTEFRAPQTATERRLAQLFGELLGRDRVGADDSFFDLGGHSLLATKLVAAVRNAFGVDVGV
REIFEFATVTALAGHIDTLDSDSARPRLTRVDHDGPVRLSSSQMRSWFNYRFDGPNAVNNIPFAAALHGPCDTNAFAAAI
TDVVARHEILRTVYREIGGVPHQIIQPPAEVPVRCAAGSDAAWLRAELNNERGYVFDLETDWPIRAALLSTPEQTVLSLV
VHHIAGDHWSAGVLFTDLLTAYRARSTGQRPSWAPLPVQYADYSVWQSALLDDGAGIVGPQRDYWIRQLGGLAGETGLRP
DFPRPALLSGAGDAVEFRLGAAIRDKLAAVSRDLGVTEFMLLQAAVAVVLHKAGGGVDVPIGAPVAGRSEANLDQLIGFF
INIVVLRNDLRGNPTLREVLQRTRQMALAAYAHQDLPFDQVVEAVNPQRSLSRNPLFDIVVHVREQMPQDHVIDTGPDGD
TTLRVLEPTFDAAQADLSVNFFACGDEYRGHVIYRTELYERATAQRFADWLVRVVEAFADRPDQPLREVEMVSAQARRRI
LDRSNAGAGTARVYLLDDALKPVPVGVVGDVYYGGGPAVGARLARPSETATRFVADPFAAQPGSRLYRNGERGVWKADGQ
LELLAEIERLPTAQAAPVPAEPADTETERALAAILADVLEVGEVGRYDDFFNLGGDSILATQVAARARDGGIPLTARMVF
EHPVLCELAAAVDAKPHVEAEPDDKHHAPMSTSGLSPDELSALTASWDQWP

Sequences:

>Translated_1731_residues
MTNTADIGARLDEARLELLRRRLADRGLSSAAQDIGPHTDDRLSDGQARMWFVQMADPSGALLNICVSYRITGDIDLARL
RDAVNAVARRHRILRTTYPVGDDGVAQPTVHADLRPGWTQYDLTDLSQRAQRLRLEVLAQREFCAPFELSRDAPLRITVV
RTAADEHVLLLVAHHIAWDDGSWRVFFTDLTQAYSRADLGADLGPEHRPSAASGPDTTEADLNYWRAIMADPPEPLELPG
PAGTCVPTSWRAARATLRLPADTAARVATMAKNTGCTPYMVLLAAFGALVHRYTHSDDFLVAAPVLNRGAGTEDAIGYFG
NTVAMRLRPQSAMSFRELLTATRDIASGAFAHQRINLDRVVRELNPDRRHGAERMTRVSFGFREPDGGGFNPPGIECERY
DLRSNITQLPLGFMVEFDRAGVLVEAEHLVEILEPALAKQMLRHFGVLLDNALAAPDNTLSGLALMDERDAARLREVSRG
ERFDTPVKTLVDLVNEQTTRTPDATAVVYEGQHFTYHDLNEASNRLGHWLIEQGIGSEDRVAVLLDKSPDLIVTALGVVK
SGAVYVPVDPSYPQDRLDFILADCDAKLVLRTPVRELAGYRSDDPTDADRIRPLRPDNTAYLIYTSGTTGLPKGVAVPHR
PVAEYFVWFKGEYDVDDTDRLLQVASPSFDVSIAEIFGTLACGARMVIPRPGGLTDIGYLTALLRDEGITAMHFVPSLLG
LFLSLPGVSQWRTLQRVPIGGEPLPGEVADKFHATFDALLHNFYGPTETVINASRFKVVGPQGTRIVPIGRPKINTTMHL
LDDSLQPVPTGVIGEIYIGGTHVAYGYHRRAGLTAERFVADPFNPGSRMYRSGDLARRNADGDIEFVGRADEQVKIRGFR
IELGDVAAAIAVDPTVGQAVVVVSDLPRLGKSLVGYVTPAAGGDGPADVGVDLDRIRARVAAALPEYMLPAAYVVLDEIP
ITAHGKIDRAALPEPQIASDTEFRAPQTATERRLAQLFGELLGRDRVGADDSFFDLGGHSLLATKLVAAVRNAFGVDVGV
REIFEFATVTALAGHIDTLDSDSARPRLTRVDHDGPVRLSSSQMRSWFNYRFDGPNAVNNIPFAAALHGPCDTNAFAAAI
TDVVARHEILRTVYREIGGVPHQIIQPPAEVPVRCAAGSDAAWLRAELNNERGYVFDLETDWPIRAALLSTPEQTVLSLV
VHHIAGDHWSAGVLFTDLLTAYRARSTGQRPSWAPLPVQYADYSVWQSALLDDGAGIVGPQRDYWIRQLGGLAGETGLRP
DFPRPALLSGAGDAVEFRLGAAIRDKLAAVSRDLGVTEFMLLQAAVAVVLHKAGGGVDVPIGAPVAGRSEANLDQLIGFF
INIVVLRNDLRGNPTLREVLQRTRQMALAAYAHQDLPFDQVVEAVNPQRSLSRNPLFDIVVHVREQMPQDHVIDTGPDGD
TTLRVLEPTFDAAQADLSVNFFACGDEYRGHVIYRTELYERATAQRFADWLVRVVEAFADRPDQPLREVEMVSAQARRRI
LDRSNAGAGTARVYLLDDALKPVPVGVVGDVYYGGGPAVGARLARPSETATRFVADPFAAQPGSRLYRNGERGVWKADGQ
LELLAEIERLPTAQAAPVPAEPADTETERALAAILADVLEVGEVGRYDDFFNLGGDSILATQVAARARDGGIPLTARMVF
EHPVLCELAAAVDAKPHVEAEPDDKHHAPMSTSGLSPDELSALTASWDQWP
>Mature_1730_residues
TNTADIGARLDEARLELLRRRLADRGLSSAAQDIGPHTDDRLSDGQARMWFVQMADPSGALLNICVSYRITGDIDLARLR
DAVNAVARRHRILRTTYPVGDDGVAQPTVHADLRPGWTQYDLTDLSQRAQRLRLEVLAQREFCAPFELSRDAPLRITVVR
TAADEHVLLLVAHHIAWDDGSWRVFFTDLTQAYSRADLGADLGPEHRPSAASGPDTTEADLNYWRAIMADPPEPLELPGP
AGTCVPTSWRAARATLRLPADTAARVATMAKNTGCTPYMVLLAAFGALVHRYTHSDDFLVAAPVLNRGAGTEDAIGYFGN
TVAMRLRPQSAMSFRELLTATRDIASGAFAHQRINLDRVVRELNPDRRHGAERMTRVSFGFREPDGGGFNPPGIECERYD
LRSNITQLPLGFMVEFDRAGVLVEAEHLVEILEPALAKQMLRHFGVLLDNALAAPDNTLSGLALMDERDAARLREVSRGE
RFDTPVKTLVDLVNEQTTRTPDATAVVYEGQHFTYHDLNEASNRLGHWLIEQGIGSEDRVAVLLDKSPDLIVTALGVVKS
GAVYVPVDPSYPQDRLDFILADCDAKLVLRTPVRELAGYRSDDPTDADRIRPLRPDNTAYLIYTSGTTGLPKGVAVPHRP
VAEYFVWFKGEYDVDDTDRLLQVASPSFDVSIAEIFGTLACGARMVIPRPGGLTDIGYLTALLRDEGITAMHFVPSLLGL
FLSLPGVSQWRTLQRVPIGGEPLPGEVADKFHATFDALLHNFYGPTETVINASRFKVVGPQGTRIVPIGRPKINTTMHLL
DDSLQPVPTGVIGEIYIGGTHVAYGYHRRAGLTAERFVADPFNPGSRMYRSGDLARRNADGDIEFVGRADEQVKIRGFRI
ELGDVAAAIAVDPTVGQAVVVVSDLPRLGKSLVGYVTPAAGGDGPADVGVDLDRIRARVAAALPEYMLPAAYVVLDEIPI
TAHGKIDRAALPEPQIASDTEFRAPQTATERRLAQLFGELLGRDRVGADDSFFDLGGHSLLATKLVAAVRNAFGVDVGVR
EIFEFATVTALAGHIDTLDSDSARPRLTRVDHDGPVRLSSSQMRSWFNYRFDGPNAVNNIPFAAALHGPCDTNAFAAAIT
DVVARHEILRTVYREIGGVPHQIIQPPAEVPVRCAAGSDAAWLRAELNNERGYVFDLETDWPIRAALLSTPEQTVLSLVV
HHIAGDHWSAGVLFTDLLTAYRARSTGQRPSWAPLPVQYADYSVWQSALLDDGAGIVGPQRDYWIRQLGGLAGETGLRPD
FPRPALLSGAGDAVEFRLGAAIRDKLAAVSRDLGVTEFMLLQAAVAVVLHKAGGGVDVPIGAPVAGRSEANLDQLIGFFI
NIVVLRNDLRGNPTLREVLQRTRQMALAAYAHQDLPFDQVVEAVNPQRSLSRNPLFDIVVHVREQMPQDHVIDTGPDGDT
TLRVLEPTFDAAQADLSVNFFACGDEYRGHVIYRTELYERATAQRFADWLVRVVEAFADRPDQPLREVEMVSAQARRRIL
DRSNAGAGTARVYLLDDALKPVPVGVVGDVYYGGGPAVGARLARPSETATRFVADPFAAQPGSRLYRNGERGVWKADGQL
ELLAEIERLPTAQAAPVPAEPADTETERALAAILADVLEVGEVGRYDDFFNLGGDSILATQVAARARDGGIPLTARMVFE
HPVLCELAAAVDAKPHVEAEPDDKHHAPMSTSGLSPDELSALTASWDQWP

Specific function: Specifically adenylates threonine and glycine, and loads them onto their corresponding peptidyl carrier domains [H]

COG id: COG1020

COG function: function code Q; Non-ribosomal peptide synthetase modules and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 acyl carrier domain [H]

Homologues:

Organism=Homo sapiens, GI45580730, Length=462, Percent_Identity=25.7575757575758, Blast_Score=112, Evalue=3e-24,
Organism=Homo sapiens, GI122937307, Length=507, Percent_Identity=21.8934911242604, Blast_Score=79, Evalue=4e-14,
Organism=Escherichia coli, GI1786801, Length=813, Percent_Identity=32.1033210332103, Blast_Score=352, Evalue=8e-98,
Organism=Escherichia coli, GI145693145, Length=526, Percent_Identity=26.8060836501901, Blast_Score=115, Evalue=3e-26,
Organism=Escherichia coli, GI1786810, Length=552, Percent_Identity=23.0072463768116, Blast_Score=92, Evalue=3e-19,
Organism=Escherichia coli, GI1788107, Length=549, Percent_Identity=23.1329690346084, Blast_Score=91, Evalue=7e-19,
Organism=Escherichia coli, GI221142682, Length=434, Percent_Identity=24.8847926267281, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17556356, Length=941, Percent_Identity=24.0170031880978, Blast_Score=144, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI17550940, Length=970, Percent_Identity=21.6494845360825, Blast_Score=124, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI17560308, Length=560, Percent_Identity=22.8571428571429, Blast_Score=93, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI32564422, Length=501, Percent_Identity=23.5528942115768, Blast_Score=83, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI32564420, Length=501, Percent_Identity=23.5528942115768, Blast_Score=83, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71994690, Length=558, Percent_Identity=20.9677419354839, Blast_Score=82, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71994694, Length=558, Percent_Identity=20.9677419354839, Blast_Score=82, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI71994703, Length=558, Percent_Identity=20.9677419354839, Blast_Score=82, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6319591, Length=901, Percent_Identity=25.9711431742508, Blast_Score=251, Evalue=1e-66,
Organism=Drosophila melanogaster, GI24648676, Length=648, Percent_Identity=29.4753086419753, Blast_Score=224, Evalue=4e-58,
Organism=Drosophila melanogaster, GI24581924, Length=398, Percent_Identity=25.8793969849246, Blast_Score=83, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR001242
- InterPro:   IPR006163
- InterPro:   IPR020806
- InterPro:   IPR001031 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF00550 PP-binding; PF00975 Thioesterase [H]

EC number: 2.7.7.- [C]

Molecular weight: Translated: 188642; Mature: 188511

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS50075 ACP_DOMAIN ; PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNTADIGARLDEARLELLRRRLADRGLSSAAQDIGPHTDDRLSDGQARMWFVQMADPSG
CCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCEEEEEEEECCCCC
ALLNICVSYRITGDIDLARLRDAVNAVARRHRILRTTYPVGDDGVAQPTVHADLRPGWTQ
CEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCEECCCCCCCCC
YDLTDLSQRAQRLRLEVLAQREFCAPFELSRDAPLRITVVRTAADEHVLLLVAHHIAWDD
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCCCEEEEEEEHHEECC
GSWRVFFTDLTQAYSRADLGADLGPEHRPSAASGPDTTEADLNYWRAIMADPPEPLELPG
CCCEEEEHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCC
PAGTCVPTSWRAARATLRLPADTAARVATMAKNTGCTPYMVLLAAFGALVHRYTHSDDFL
CCCCCCCCCCHHHHEEEECCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCEE
VAAPVLNRGAGTEDAIGYFGNTVAMRLRPQSAMSFRELLTATRDIASGAFAHQRINLDRV
EECCHHCCCCCCCHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHCHHHHHHCCHHHH
VRELNPDRRHGAERMTRVSFGFREPDGGGFNPPGIECERYDLRSNITQLPLGFMVEFDRA
HHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEHHHCCHHHCCCCEEEEECCC
GVLVEAEHLVEILEPALAKQMLRHFGVLLDNALAAPDNTLSGLALMDERDAARLREVSRG
CCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCHHHHHHHHHHCC
ERFDTPVKTLVDLVNEQTTRTPDATAVVYEGQHFTYHDLNEASNRLGHWLIEQGIGSEDR
CCCCCHHHHHHHHHCCCCCCCCCCEEEEECCCCCEECCHHHHHHHHHHHHHHHCCCCCCC
VAVLLDKSPDLIVTALGVVKSGAVYVPVDPSYPQDRLDFILADCDAKLVLRTPVRELAGY
EEEEEECCCCEEEHHHHHHHCCCEEEECCCCCCHHHHHEEEECCCCEEEEECCHHHHCCC
RSDDPTDADRIRPLRPDNTAYLIYTSGTTGLPKGVAVPHRPVAEYFVWFKGEYDVDDTDR
CCCCCCCHHHCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCHHHEEEEECCCCCCCHHHH
LLQVASPSFDVSIAEIFGTLACGARMVIPRPGGLTDIGYLTALLRDEGITAMHFVPSLLG
HHHHCCCCCCEEHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHH
LFLSLPGVSQWRTLQRVPIGGEPLPGEVADKFHATFDALLHNFYGPTETVINASRFKVVG
HHHCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCEEEEC
PQGTRIVPIGRPKINTTMHLLDDSLQPVPTGVIGEIYIGGTHVAYGYHRRAGLTAERFVA
CCCCEEEECCCCCCCHHHHHHHCCCCCCCCCCEEEEEECCEEEEECHHHHCCCCHHHHCC
DPFNPGSRMYRSGDLARRNADGDIEFVGRADEQVKIRGFRIELGDVAAAIAVDPTVGQAV
CCCCCCHHHHCCCCHHHCCCCCCEEEEECCCCEEEEEEEEEEHHHEEEEEEECCCCCCEE
VVVSDLPRLGKSLVGYVTPAAGGDGPADVGVDLDRIRARVAAALPEYMLPAAYVVLDEIP
EEEHHHHHHHHHHHHEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
ITAHGKIDRAALPEPQIASDTEFRAPQTATERRLAQLFGELLGRDRVGADDSFFDLGGHS
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCHH
LLATKLVAAVRNAFGVDVGVREIFEFATVTALAGHIDTLDSDSARPRLTRVDHDGPVRLS
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCEEEC
SSQMRSWFNYRFDGPNAVNNIPFAAALHGPCDTNAFAAAITDVVARHEILRTVYREIGGV
HHHHHHHHCEECCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
PHQIIQPPAEVPVRCAAGSDAAWLRAELNNERGYVFDLETDWPIRAALLSTPEQTVLSLV
CHHHHCCCHHCCEEEECCCCCEEEEEEECCCCCEEEEECCCCCHHHHHHCCCHHHHHHHH
VHHIAGDHWSAGVLFTDLLTAYRARSTGQRPSWAPLPVQYADYSVWQSALLDDGAGIVGP
HHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCC
QRDYWIRQLGGLAGETGLRPDFPRPALLSGAGDAVEFRLGAAIRDKLAAVSRDLGVTEFM
CHHHHHHHHCCCCCCCCCCCCCCCCHHHCCCCCCEEEHHHHHHHHHHHHHHHCCCHHHHH
LLQAAVAVVLHKAGGGVDVPIGAPVAGRSEANLDQLIGFFINIVVLRNDLRGNPTLREVL
HHHHHHHHHHHHCCCCEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHH
QRTRQMALAAYAHQDLPFDQVVEAVNPQRSLSRNPLFDIVVHVREQMPQDHVIDTGPDGD
HHHHHHHHHHHHHCCCCHHHHHHHCCCHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCC
TTLRVLEPTFDAAQADLSVNFFACGDEYRGHVIYRTELYERATAQRFADWLVRVVEAFAD
CEEEEECCCCCCHHCCCEEEEEEECCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHC
RPDQPLREVEMVSAQARRRILDRSNAGAGTARVYLLDDALKPVPVGVVGDVYYGGGPAVG
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCEEEECCEECCCHHHH
ARLARPSETATRFVADPFAAQPGSRLYRNGERGVWKADGQLELLAEIERLPTAQAAPVPA
HCCCCCCHHHHHHHCCCCCCCCCHHHHHCCCCCEEECCCCHHHHHHHHHCCCCCCCCCCC
EPADTETERALAAILADVLEVGEVGRYDDFFNLGGDSILATQVAARARDGGIPLTARMVF
CCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCHHHHHHHHHHHCCCCCCEEEHHHH
EHPVLCELAAAVDAKPHVEAEPDDKHHAPMSTSGLSPDELSALTASWDQWP
CCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TNTADIGARLDEARLELLRRRLADRGLSSAAQDIGPHTDDRLSDGQARMWFVQMADPSG
CCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCEEEEEEEECCCCC
ALLNICVSYRITGDIDLARLRDAVNAVARRHRILRTTYPVGDDGVAQPTVHADLRPGWTQ
CEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCEECCCCCCCCC
YDLTDLSQRAQRLRLEVLAQREFCAPFELSRDAPLRITVVRTAADEHVLLLVAHHIAWDD
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCCCEEEEEEEHHEECC
GSWRVFFTDLTQAYSRADLGADLGPEHRPSAASGPDTTEADLNYWRAIMADPPEPLELPG
CCCEEEEHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCC
PAGTCVPTSWRAARATLRLPADTAARVATMAKNTGCTPYMVLLAAFGALVHRYTHSDDFL
CCCCCCCCCCHHHHEEEECCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCEE
VAAPVLNRGAGTEDAIGYFGNTVAMRLRPQSAMSFRELLTATRDIASGAFAHQRINLDRV
EECCHHCCCCCCCHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHCHHHHHHCCHHHH
VRELNPDRRHGAERMTRVSFGFREPDGGGFNPPGIECERYDLRSNITQLPLGFMVEFDRA
HHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEHHHCCHHHCCCCEEEEECCC
GVLVEAEHLVEILEPALAKQMLRHFGVLLDNALAAPDNTLSGLALMDERDAARLREVSRG
CCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCHHHHHHHHHHCC
ERFDTPVKTLVDLVNEQTTRTPDATAVVYEGQHFTYHDLNEASNRLGHWLIEQGIGSEDR
CCCCCHHHHHHHHHCCCCCCCCCCEEEEECCCCCEECCHHHHHHHHHHHHHHHCCCCCCC
VAVLLDKSPDLIVTALGVVKSGAVYVPVDPSYPQDRLDFILADCDAKLVLRTPVRELAGY
EEEEEECCCCEEEHHHHHHHCCCEEEECCCCCCHHHHHEEEECCCCEEEEECCHHHHCCC
RSDDPTDADRIRPLRPDNTAYLIYTSGTTGLPKGVAVPHRPVAEYFVWFKGEYDVDDTDR
CCCCCCCHHHCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCHHHEEEEECCCCCCCHHHH
LLQVASPSFDVSIAEIFGTLACGARMVIPRPGGLTDIGYLTALLRDEGITAMHFVPSLLG
HHHHCCCCCCEEHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHH
LFLSLPGVSQWRTLQRVPIGGEPLPGEVADKFHATFDALLHNFYGPTETVINASRFKVVG
HHHCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCEEEEC
PQGTRIVPIGRPKINTTMHLLDDSLQPVPTGVIGEIYIGGTHVAYGYHRRAGLTAERFVA
CCCCEEEECCCCCCCHHHHHHHCCCCCCCCCCEEEEEECCEEEEECHHHHCCCCHHHHCC
DPFNPGSRMYRSGDLARRNADGDIEFVGRADEQVKIRGFRIELGDVAAAIAVDPTVGQAV
CCCCCCHHHHCCCCHHHCCCCCCEEEEECCCCEEEEEEEEEEHHHEEEEEEECCCCCCEE
VVVSDLPRLGKSLVGYVTPAAGGDGPADVGVDLDRIRARVAAALPEYMLPAAYVVLDEIP
EEEHHHHHHHHHHHHEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
ITAHGKIDRAALPEPQIASDTEFRAPQTATERRLAQLFGELLGRDRVGADDSFFDLGGHS
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCHH
LLATKLVAAVRNAFGVDVGVREIFEFATVTALAGHIDTLDSDSARPRLTRVDHDGPVRLS
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCEEEC
SSQMRSWFNYRFDGPNAVNNIPFAAALHGPCDTNAFAAAITDVVARHEILRTVYREIGGV
HHHHHHHHCEECCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
PHQIIQPPAEVPVRCAAGSDAAWLRAELNNERGYVFDLETDWPIRAALLSTPEQTVLSLV
CHHHHCCCHHCCEEEECCCCCEEEEEEECCCCCEEEEECCCCCHHHHHHCCCHHHHHHHH
VHHIAGDHWSAGVLFTDLLTAYRARSTGQRPSWAPLPVQYADYSVWQSALLDDGAGIVGP
HHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCC
QRDYWIRQLGGLAGETGLRPDFPRPALLSGAGDAVEFRLGAAIRDKLAAVSRDLGVTEFM
CHHHHHHHHCCCCCCCCCCCCCCCCHHHCCCCCCEEEHHHHHHHHHHHHHHHCCCHHHHH
LLQAAVAVVLHKAGGGVDVPIGAPVAGRSEANLDQLIGFFINIVVLRNDLRGNPTLREVL
HHHHHHHHHHHHCCCCEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHH
QRTRQMALAAYAHQDLPFDQVVEAVNPQRSLSRNPLFDIVVHVREQMPQDHVIDTGPDGD
HHHHHHHHHHHHHCCCCHHHHHHHCCCHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCC
TTLRVLEPTFDAAQADLSVNFFACGDEYRGHVIYRTELYERATAQRFADWLVRVVEAFAD
CEEEEECCCCCCHHCCCEEEEEEECCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHC
RPDQPLREVEMVSAQARRRILDRSNAGAGTARVYLLDDALKPVPVGVVGDVYYGGGPAVG
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCEEEECCEECCCHHHH
ARLARPSETATRFVADPFAAQPGSRLYRNGERGVWKADGQLELLAEIERLPTAQAAPVPA
HCCCCCCHHHHHHHCCCCCCCCCHHHHHCCCCCEEECCCCHHHHHHHHHCCCCCCCCCCC
EPADTETERALAAILADVLEVGEVGRYDDFFNLGGDSILATQVAARARDGGIPLTARMVF
CCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCHHHHHHHHHHHCCCCCCEEEHHHH
EHPVLCELAAAVDAKPHVEAEPDDKHHAPMSTSGLSPDELSALTASWDQWP
CCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Phosphopantetheine. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate [C]

Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Seryl-AMP 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Ser

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11112781; 9384377; 10568751; 8550523 [H]