Click here to switch to the map view.

The map label for this gene is 148823546

Identifier: 148823546

GI number: 148823546

Start: 2634618

End: 2636600

Strand: Direct

Name: 148823546

Synonym: TBFG_12369

Alternate gene names: NA

Gene position: 2634618-2636600 (Clockwise)

Preceding gene: 148823543

Following gene: 148823554

Centisome position: 59.55

GC content: 67.83

Gene sequence:

>1983_bases
ATGCGTCTCGTTCGCCTGCTCGGCATGGTCCTGACTATCCTCGCCGCCGGGCTGCTGCTGGGGCCGCCCGCTGGCGCGCA
ACCACCTTTCCGGCTGTCGAACTACGTGACCGACAACGCGGGCGTGCTGACTAGCTCCGGTCGCACCGCGGTGACGGCGG
CCGTCGACCGGCTCTATGCCGATCGCCGCATCCGACTGTGGGTGGTCTACGTCGAGAACTTCTCCGGTCAGAGTGCGCTC
AACTGGGCGCAGCGCACGACGCGGACTAGCGAGCTGGGTAACTATGACGCGCTTCTGGCCGTGGCCACCACCGGTCGCGA
ATATGCCTTTCTAGTGCCATCCGCGATGCCGGGTGTCAGCGAGGGGCAGGTCGACAACGTGCGGCGCTATCAGATCGAAC
CGGCGCTGCACGACGGCGACTACAGCGGCGCGGCCGTTGCGGCGGCGAACGGACTCAACCGGTCACCCAGTTCGTCGAGT
CGAGTGGTGTTGTTGGTCACGGTCGGCATCATCGTCATCGTCGTCGCGGTCCTGCTGGTGGTGATGCGCCACCGCAACCG
GCGGCGCCGCGCCGACGAGCTGGCCGCGGCACGCCGCGTCGACCCTACCAACGTAATGGCACTGGCCGCCGTGCCGCTTC
AGGCCCTCGATGACCTCTCCCGGTCGATGGTGGTAGACGTCGACAACGCCGTGCGCACCAGCACCAACGAGCTCGCGCTG
GCCATCGAGGAGTTCGGCGAACGGCGAACCGCACCGTTTACCCAAGCGGTGAACAACGCCAAAGCGGCTCTGTCCCAGGC
GTTCACCGTACGCCAACAACTTGATGACAACACGCCCGAGACGCCGGCGCAGCGACGTGAGCTACTCACCCGAGTGATCG
TGTCGGCGGCGCACGCCGACCGTGAACTCGCGTCGCAAACCGAGGCCTTCGAGAAGCTACGCGATTTGGTGATCAACGCC
CCGGCCCGGCTTGATCTGCTCACCCAGCAGTACGTCGAACTGACCACCCGGATCGGCCCGACTCAGCAACGCCTGGCCGA
GCTGCATACCGAATTCGACGCTGCGGCGATGACGTCGATCGCCGGCAATGTCACCACCGCCACCGAGCGGCTGGCGTTCG
CCGACCGTAACATCAGCGCGGCTCGGGATCTGGCCGACCAGGCAGTGAGCGGACGGCAAGCCGGACTGGTGGATGCGGTG
CGTGCCGCCGAGTCGGCACTCGGGCAAGCCCGGGCGCTGCTCGACGCGGTGGACAGCGCCGCCACCGACATCCGGCACGC
CGTCGCGTCGCTGCCGGCGGTCGTGGCCGACATCCAGACGGGCATCAAGCGAGCCAACCAACACCTACAGCAGGCGCAAC
AACCCCAAACCGGGCGCACCGGTGACCTGATCGCAGCCCGCGATGCGGCGGCCAGGGCCCTCGATCGCGCGCGCGGAGCC
GCCGATCCGTTGACCGCATTTGACCAGTTGACCAAGGTCGACGCTGACCTCGACCGGCTGCTCGCCACCCTGGCCGAAGA
ACAGGCAACCGCCGATCGGCTCAACCGCTCACTTGAGCAGGCGCTGTTTACCGCGGAGTCGCGGGTGCGCGCCGTCTCGG
AGTACATCGACACCCGCCGCGGCAGCATCGGGCCGGAGGCCCGGACCCGGCTGGCCGAGGCGAAACGGCAGCTGGAAGCC
GCACATGACCGGAAATCGAGCAACCCGACCGAAGCGATCGCCTACGCTAACGCGGCATCGACGCTGGCCGCACATGCGCA
GTCGCTGGCCAATGCCGACGTGCAATCCGCCCAGCGCGCATACACCCGTCGTGGGGGCAACAACGCCGGCGCGATCCTCG
GTGGCATCATCATCGGCGACCTGCTTAGCGGAGGCACCAGAGGCGGGTTGGGTGGATGGATCCCCACGTCGTTCGGCGGT
TCGTCGAACGCGCCGGGAAGTTCACCCGACGGCGGGTTCTTGGGCGGCGGCGGGCGGTTCTAA

Upstream 100 bases:

>100_bases
TCGTCGTAGGGGTCGTGCTCACTCGCGCTCACCGACCCACAGTCTGCCAGGGTGGTCGCCGCACGCCCGTATCCGCCGGC
ACAGCGTCTAAATTGACGGT

Downstream 100 bases:

>100_bases
GCCACGCGCCAGCGCACGGGGATACCCGTACGCTGGCGCGTGTGGCCGTCGACCTAGGCTTCTTCCTAGGGTTCGTCGAC
CCTGTCAGGCCCAGCTGGAG

Product: transmembrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 660; Mature: 660

Protein sequence:

>660_residues
MRLVRLLGMVLTILAAGLLLGPPAGAQPPFRLSNYVTDNAGVLTSSGRTAVTAAVDRLYADRRIRLWVVYVENFSGQSAL
NWAQRTTRTSELGNYDALLAVATTGREYAFLVPSAMPGVSEGQVDNVRRYQIEPALHDGDYSGAAVAAANGLNRSPSSSS
RVVLLVTVGIIVIVVAVLLVVMRHRNRRRRADELAAARRVDPTNVMALAAVPLQALDDLSRSMVVDVDNAVRTSTNELAL
AIEEFGERRTAPFTQAVNNAKAALSQAFTVRQQLDDNTPETPAQRRELLTRVIVSAAHADRELASQTEAFEKLRDLVINA
PARLDLLTQQYVELTTRIGPTQQRLAELHTEFDAAAMTSIAGNVTTATERLAFADRNISAARDLADQAVSGRQAGLVDAV
RAAESALGQARALLDAVDSAATDIRHAVASLPAVVADIQTGIKRANQHLQQAQQPQTGRTGDLIAARDAAARALDRARGA
ADPLTAFDQLTKVDADLDRLLATLAEEQATADRLNRSLEQALFTAESRVRAVSEYIDTRRGSIGPEARTRLAEAKRQLEA
AHDRKSSNPTEAIAYANAASTLAAHAQSLANADVQSAQRAYTRRGGNNAGAILGGIIIGDLLSGGTRGGLGGWIPTSFGG
SSNAPGSSPDGGFLGGGGRF

Sequences:

>Translated_660_residues
MRLVRLLGMVLTILAAGLLLGPPAGAQPPFRLSNYVTDNAGVLTSSGRTAVTAAVDRLYADRRIRLWVVYVENFSGQSAL
NWAQRTTRTSELGNYDALLAVATTGREYAFLVPSAMPGVSEGQVDNVRRYQIEPALHDGDYSGAAVAAANGLNRSPSSSS
RVVLLVTVGIIVIVVAVLLVVMRHRNRRRRADELAAARRVDPTNVMALAAVPLQALDDLSRSMVVDVDNAVRTSTNELAL
AIEEFGERRTAPFTQAVNNAKAALSQAFTVRQQLDDNTPETPAQRRELLTRVIVSAAHADRELASQTEAFEKLRDLVINA
PARLDLLTQQYVELTTRIGPTQQRLAELHTEFDAAAMTSIAGNVTTATERLAFADRNISAARDLADQAVSGRQAGLVDAV
RAAESALGQARALLDAVDSAATDIRHAVASLPAVVADIQTGIKRANQHLQQAQQPQTGRTGDLIAARDAAARALDRARGA
ADPLTAFDQLTKVDADLDRLLATLAEEQATADRLNRSLEQALFTAESRVRAVSEYIDTRRGSIGPEARTRLAEAKRQLEA
AHDRKSSNPTEAIAYANAASTLAAHAQSLANADVQSAQRAYTRRGGNNAGAILGGIIIGDLLSGGTRGGLGGWIPTSFGG
SSNAPGSSPDGGFLGGGGRF
>Mature_660_residues
MRLVRLLGMVLTILAAGLLLGPPAGAQPPFRLSNYVTDNAGVLTSSGRTAVTAAVDRLYADRRIRLWVVYVENFSGQSAL
NWAQRTTRTSELGNYDALLAVATTGREYAFLVPSAMPGVSEGQVDNVRRYQIEPALHDGDYSGAAVAAANGLNRSPSSSS
RVVLLVTVGIIVIVVAVLLVVMRHRNRRRRADELAAARRVDPTNVMALAAVPLQALDDLSRSMVVDVDNAVRTSTNELAL
AIEEFGERRTAPFTQAVNNAKAALSQAFTVRQQLDDNTPETPAQRRELLTRVIVSAAHADRELASQTEAFEKLRDLVINA
PARLDLLTQQYVELTTRIGPTQQRLAELHTEFDAAAMTSIAGNVTTATERLAFADRNISAARDLADQAVSGRQAGLVDAV
RAAESALGQARALLDAVDSAATDIRHAVASLPAVVADIQTGIKRANQHLQQAQQPQTGRTGDLIAARDAAARALDRARGA
ADPLTAFDQLTKVDADLDRLLATLAEEQATADRLNRSLEQALFTAESRVRAVSEYIDTRRGSIGPEARTRLAEAKRQLEA
AHDRKSSNPTEAIAYANAASTLAAHAQSLANADVQSAQRAYTRRGGNNAGAILGGIIIGDLLSGGTRGGLGGWIPTSFGG
SSNAPGSSPDGGFLGGGGRF

Specific function: May play a role in septum formation

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0603 family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y2345_MYCTU (P95241)

Other databases:

- EMBL:   AE000516
- EMBL:   BX842579
- PIR:   B70662
- RefSeq:   NP_216861.1
- RefSeq:   NP_336889.1
- ProteinModelPortal:   P95241
- EnsemblBacteria:   EBMYCT00000003339
- EnsemblBacteria:   EBMYCT00000072703
- GeneID:   888960
- GeneID:   923999
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT2410
- KEGG:   mtu:Rv2345
- TIGR:   MT2410
- TubercuList:   Rv2345
- GeneTree:   EBGT00050000015097
- HOGENOM:   HBG566640
- OMA:   DDAIPET
- ProtClustDB:   CLSK872053
- InterPro:   IPR007621

Pfam domain/function: PF04536 DUF477

EC number: NA

Molecular weight: Translated: 70030; Mature: 70030

Theoretical pI: Translated: 8.71; Mature: 8.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1b75270c)-; HASH(0xbf48f1c)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLVRLLGMVLTILAAGLLLGPPAGAQPPFRLSNYVTDNAGVLTSSGRTAVTAAVDRLYA
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCCEEECCCCHHHHHHHHHHHH
DRRIRLWVVYVENFSGQSALNWAQRTTRTSELGNYDALLAVATTGREYAFLVPSAMPGVS
CCEEEEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEECCCCCCCCC
EGQVDNVRRYQIEPALHDGDYSGAAVAAANGLNRSPSSSSRVVLLVTVGIIVIVVAVLLV
CCCCCCCHHEEECCCCCCCCCCCCHHHHHCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHH
VMRHRNRRRRADELAAARRVDPTNVMALAAVPLQALDDLSRSMVVDVDNAVRTSTNELAL
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHEEEECCHHHHCCCHHHHH
AIEEFGERRTAPFTQAVNNAKAALSQAFTVRQQLDDNTPETPAQRRELLTRVIVSAAHAD
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
RELASQTEAFEKLRDLVINAPARLDLLTQQYVELTTRIGPTQQRLAELHTEFDAAAMTSI
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
AGNVTTATERLAFADRNISAARDLADQAVSGRQAGLVDAVRAAESALGQARALLDAVDSA
CCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ATDIRHAVASLPAVVADIQTGIKRANQHLQQAQQPQTGRTGDLIAARDAAARALDRARGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHHCCC
ADPLTAFDQLTKVDADLDRLLATLAEEQATADRLNRSLEQALFTAESRVRAVSEYIDTRR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GSIGPEARTRLAEAKRQLEAAHDRKSSNPTEAIAYANAASTLAAHAQSLANADVQSAQRA
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YTRRGGNNAGAILGGIIIGDLLSGGTRGGLGGWIPTSFGGSSNAPGSSPDGGFLGGGGRF
HHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCH
>Mature Secondary Structure
MRLVRLLGMVLTILAAGLLLGPPAGAQPPFRLSNYVTDNAGVLTSSGRTAVTAAVDRLYA
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCCEEECCCCHHHHHHHHHHHH
DRRIRLWVVYVENFSGQSALNWAQRTTRTSELGNYDALLAVATTGREYAFLVPSAMPGVS
CCEEEEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEECCCCCCCCC
EGQVDNVRRYQIEPALHDGDYSGAAVAAANGLNRSPSSSSRVVLLVTVGIIVIVVAVLLV
CCCCCCCHHEEECCCCCCCCCCCCHHHHHCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHH
VMRHRNRRRRADELAAARRVDPTNVMALAAVPLQALDDLSRSMVVDVDNAVRTSTNELAL
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHEEEECCHHHHCCCHHHHH
AIEEFGERRTAPFTQAVNNAKAALSQAFTVRQQLDDNTPETPAQRRELLTRVIVSAAHAD
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
RELASQTEAFEKLRDLVINAPARLDLLTQQYVELTTRIGPTQQRLAELHTEFDAAAMTSI
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
AGNVTTATERLAFADRNISAARDLADQAVSGRQAGLVDAVRAAESALGQARALLDAVDSA
CCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ATDIRHAVASLPAVVADIQTGIKRANQHLQQAQQPQTGRTGDLIAARDAAARALDRARGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHHCCC
ADPLTAFDQLTKVDADLDRLLATLAEEQATADRLNRSLEQALFTAESRVRAVSEYIDTRR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GSIGPEARTRLAEAKRQLEAAHDRKSSNPTEAIAYANAASTLAAHAQSLANADVQSAQRA
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YTRRGGNNAGAILGGIIIGDLLSGGTRGGLGGWIPTSFGGSSNAPGSSPDGGFLGGGGRF
HHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036