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The map label for this gene is 148823500

Identifier: 148823500

GI number: 148823500

Start: 2582864

End: 2583796

Strand: Reverse

Name: 148823500

Synonym: TBFG_12323

Alternate gene names: NA

Gene position: 2583796-2582864 (Counterclockwise)

Preceding gene: 148823503

Following gene: 148823499

Centisome position: 58.4

GC content: 64.84

Gene sequence:

>933_bases
ATGGTAGCGACCCGCGGCCGCCCGTGCCCGACCAATTTTTCCAGGCCGCAGCGGCCCCGAGTGGCCGGCAATGGCACAAA
GTCCCAGCGGTGTCGCGGTAGGTTGACGACCAGTATGTTAGGTGTCGCCCCCGAAGCGAAGGGACCGCCGGTGAAGGTCC
ACCACCTCAACTGCGGCACCATGAATGCATTTGGCATCGCTCTGTTATGCCACGTTCTGCTCGTCGAGACCGACGATGGA
TTGGTGCTGGTGGACACCGGCTTCGGTATCCAGGACTGCCTTGACCCCGGCCGGGTAGGTCTATTCCGTCATGTCCTGCG
GCCGGCATTCTTGCAGGCCGAAACCGCGGCCCGCCAGATCGAACAGCTCGGCTACCGCACGTCCGACGTTCGACACATTG
TGCTCACCCACTTCGACTTCGACCACATCGGCGGGATCGCCGACTTCCCCGAGGCTCACCTCCACGTCACCGCCGCCGAA
GCCCGCGGTGCCATCCACGCCCCTTCGCTCCGCGAGCGACTGCGATATCGACGCGGACAGTGGGCCCACGGCCCGAAGCT
GGTGGAGCACGGTCCCGACGGGGAACCCTGGCGCGGATTCGCATCGGCCAAACCCCTCGATTCCATCGGCACCGGTGTCG
TTCTGGTGCCGATGCCCGGTCACACCCGCGGGCACGCCGCGGTAGCTGTCGATGCCGGTCACCGCTGGGTTTTGCACTGC
GGCGACGCCTTCTATCATCGCGGCACCCTCGATGGCCGGTTCCGGGTGCCCTTCGTGATGCGGGCCGAGGAAAAGCTGTT
GTCGTATAACCGCAACCAACTGCGCGACAACCAGGCCCGAATCGTCGAACTCCATCGACGCCACGACCCGGATCTACTCA
TCGTCTGCGCACACGATCCCGACCTCTATCAGCTTGCTCGCGATACGGCCTAG

Upstream 100 bases:

>100_bases
CGGGAACGGTGATGGGAGTAAGCAGAAGCACCGCGGCCAGCATTGCGGCGGCCGCGCCCATGGTGAGCAGTCGGCGGGTC
AGTAAATCATTCACAGTGGG

Downstream 100 bases:

>100_bases
CCAGGCCACCCCCAGCTCGGCGCCGGATCGCAGCTCGCTAAATTCGAGTCGCTATGTCGTCGGAAGGAATCTCATGAACG
CCCATGTCGAGCAGTTGGAG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MVATRGRPCPTNFSRPQRPRVAGNGTKSQRCRGRLTTSMLGVAPEAKGPPVKVHHLNCGTMNAFGIALLCHVLLVETDDG
LVLVDTGFGIQDCLDPGRVGLFRHVLRPAFLQAETAARQIEQLGYRTSDVRHIVLTHFDFDHIGGIADFPEAHLHVTAAE
ARGAIHAPSLRERLRYRRGQWAHGPKLVEHGPDGEPWRGFASAKPLDSIGTGVVLVPMPGHTRGHAAVAVDAGHRWVLHC
GDAFYHRGTLDGRFRVPFVMRAEEKLLSYNRNQLRDNQARIVELHRRHDPDLLIVCAHDPDLYQLARDTA

Sequences:

>Translated_310_residues
MVATRGRPCPTNFSRPQRPRVAGNGTKSQRCRGRLTTSMLGVAPEAKGPPVKVHHLNCGTMNAFGIALLCHVLLVETDDG
LVLVDTGFGIQDCLDPGRVGLFRHVLRPAFLQAETAARQIEQLGYRTSDVRHIVLTHFDFDHIGGIADFPEAHLHVTAAE
ARGAIHAPSLRERLRYRRGQWAHGPKLVEHGPDGEPWRGFASAKPLDSIGTGVVLVPMPGHTRGHAAVAVDAGHRWVLHC
GDAFYHRGTLDGRFRVPFVMRAEEKLLSYNRNQLRDNQARIVELHRRHDPDLLIVCAHDPDLYQLARDTA
>Mature_310_residues
MVATRGRPCPTNFSRPQRPRVAGNGTKSQRCRGRLTTSMLGVAPEAKGPPVKVHHLNCGTMNAFGIALLCHVLLVETDDG
LVLVDTGFGIQDCLDPGRVGLFRHVLRPAFLQAETAARQIEQLGYRTSDVRHIVLTHFDFDHIGGIADFPEAHLHVTAAE
ARGAIHAPSLRERLRYRRGQWAHGPKLVEHGPDGEPWRGFASAKPLDSIGTGVVLVPMPGHTRGHAAVAVDAGHRWVLHC
GDAFYHRGTLDGRFRVPFVMRAEEKLLSYNRNQLRDNQARIVELHRRHDPDLLIVCAHDPDLYQLARDTA

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y2300_MYCTU (P64981)

Other databases:

- EMBL:   BX842579
- EMBL:   AE000516
- PIR:   H70733
- RefSeq:   NP_216816.1
- RefSeq:   NP_336828.1
- ProteinModelPortal:   P64981
- EnsemblBacteria:   EBMYCT00000002265
- EnsemblBacteria:   EBMYCT00000070042
- GeneID:   887880
- GeneID:   924064
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT2357
- KEGG:   mtu:Rv2300c
- TIGR:   MT2357
- TubercuList:   Rv2300c
- GeneTree:   EBGT00050000017234
- HOGENOM:   HBG369977
- OMA:   RVHHLNC
- ProtClustDB:   CLSK872045
- InterPro:   IPR001279
- SMART:   SM00849

Pfam domain/function: PF00753 Lactamase_B

EC number: NA

Molecular weight: Translated: 34353; Mature: 34353

Theoretical pI: Translated: 9.12; Mature: 9.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVATRGRPCPTNFSRPQRPRVAGNGTKSQRCRGRLTTSMLGVAPEAKGPPVKVHHLNCGT
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCC
MNAFGIALLCHVLLVETDDGLVLVDTGFGIQDCLDPGRVGLFRHVLRPAFLQAETAARQI
CHHHHHHHHHHHHEEECCCCEEEEECCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
EQLGYRTSDVRHIVLTHFDFDHIGGIADFPEAHLHVTAAEARGAIHAPSLRERLRYRRGQ
HHHCCCCCCCEEEEEEECCHHHHCCCCCCCCCEEEEEEHHCCCCCCCHHHHHHHHHHCCC
WAHGPKLVEHGPDGEPWRGFASAKPLDSIGTGVVLVPMPGHTRGHAAVAVDAGHRWVLHC
CCCCCCHHHCCCCCCCCCCCCCCCCCHHCCCCEEEEECCCCCCCCEEEEEECCCEEEEEE
GDAFYHRGTLDGRFRVPFVMRAEEKLLSYNRNQLRDNQARIVELHRRHDPDLLIVCAHDP
CCHHEECCCCCCEEECCEEECHHHHHHHCCHHHHCCCHHHHHHHHHCCCCCEEEEECCCC
DLYQLARDTA
HHHHHHHCCC
>Mature Secondary Structure
MVATRGRPCPTNFSRPQRPRVAGNGTKSQRCRGRLTTSMLGVAPEAKGPPVKVHHLNCGT
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCC
MNAFGIALLCHVLLVETDDGLVLVDTGFGIQDCLDPGRVGLFRHVLRPAFLQAETAARQI
CHHHHHHHHHHHHEEECCCCEEEEECCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
EQLGYRTSDVRHIVLTHFDFDHIGGIADFPEAHLHVTAAEARGAIHAPSLRERLRYRRGQ
HHHCCCCCCCEEEEEEECCHHHHCCCCCCCCCEEEEEEHHCCCCCCCHHHHHHHHHHCCC
WAHGPKLVEHGPDGEPWRGFASAKPLDSIGTGVVLVPMPGHTRGHAAVAVDAGHRWVLHC
CCCCCCHHHCCCCCCCCCCCCCCCCCHHCCCCEEEEECCCCCCCCEEEEEECCCEEEEEE
GDAFYHRGTLDGRFRVPFVMRAEEKLLSYNRNQLRDNQARIVELHRRHDPDLLIVCAHDP
CCHHEECCCCCCEEECCEEECHHHHHHHCCHHHHCCCHHHHHHHHHCCCCCEEEEECCCC
DLYQLARDTA
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036