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The map label for this gene is 148823450

Identifier: 148823450

GI number: 148823450

Start: 2527450

End: 2528694

Strand: Direct

Name: 148823450

Synonym: TBFG_12271

Alternate gene names: NA

Gene position: 2527450-2528694 (Clockwise)

Preceding gene: 148823449

Following gene: 148823451

Centisome position: 57.12

GC content: 67.23

Gene sequence:

>1245_bases
GTGAACGACAATCAGTTGGCTCCAGTTGCCCGCCCGAGGTCGCCGCTCGAACTGCTGGACACTGTGCCCGATTCGCTGCT
GCGGCGGTTGAAGCAGTACTCGGGCCGGCTGGCCACCGAGGCAGTTTCGGCCATGCAAGAACGGTTGCCGTTCTTCGCCG
ACCTAGAAGCGTCCCAGCGCGCCAGCGTGGCGCTGGTGGTGCAGACGGCCGTGGTCAACTTCGTCGAATGGATGCACGAC
CCGCACAGTGACGTCGGCTATACCGCGCAGGCATTCGAGCTGGTGCCCCAGGATCTGACGCGACGGATCGCGCTGCGCCA
GACCGTGGACATGGTGCGGGTCACCATGGAGTTCTTCGAAGAAGTCGTGCCCCTGCTCGCCCGTTCCGAAGAGCAGTTGA
CCGCCCTCACGGTGGGCATTTTGAAATACAGCCGCGACCTGGCATTCACCGCCGCCACGGCCTACGCCGATGCGGCCGAG
GCACGAGGCACCTGGGACAGCCGGATGGAGGCCAGCGTGGTGGACGCGGTGGTACGCGGCGACACCGGTCCCGAGCTGCT
GTCCCGGGCGGCCGCGCTGAATTGGGACACCACCGCGCCGGCGACCGTACTGGTGGGAACTCCGGCGCCCGGTCCAAATG
GCTCCAACAGCGACGGCGACAGCGAGCGGGCCAGCCAGGATGTCCGCGACACCGCGGCTCGCCACGGCCGCGCTGCGCTG
ACCGACGTGCACGGCACCTGGCTGGTGGCGATCGTCTCCGGCCAGCTGTCGCCAACCGAGAAGTTCCTCAAAGACCTGCT
GGCAGCATTCGCCGACGCCCCGGTGGTCATCGGCCCCACGGCGCCCATGCTGACCGCGGCGCACCGCAGCGCTAGCGAGG
CGATCTCCGGGATGAACGCCGTCGCCGGCTGGCGCGGAGCGCCGCGGCCCGTGCTGGCTAGGGAACTTTTGCCCGAACGC
GCCCTGATGGGCGACGCCTCGGCGATCGTGGCCCTGCATACCGACGTGATGCGGCCCCTAGCCGATGCCGGACCGACGCT
CATCGAGACGCTAGACGCATATCTGGATTGTGGCGGCGCGATTGAAGCTTGTGCCAGAAAGTTGTTCGTTCATCCAAACA
CAGTGCGGTACCGGCTCAAGCGGATCACCGACTTCACCGGGCGCGATCCCACCCAGCCACGCGATGCCTATGTCCTTCGG
GTGGCGGCCACCGTGGGTCAACTCAACTATCCGACGCCGCACTGA

Upstream 100 bases:

>100_bases
CTGCGCCCGAGCAGACCACGGATCCCGGTCCCGGGGCCTAACGCCGGCGAGCCGACCGCCTTTGGCCGAATCTTCCAGAA
ATCTGGCGTAGCTTTTAGGA

Downstream 100 bases:

>100_bases
AGCATCGACAGCAATGCCGTGTCATAGATTCCCTCGCCGGTCAGAGGGGGTCCAGCAGGGGCCCCGGAAAGATACCAGGG
GCGCCGTCGGACGGAAAGTG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 414; Mature: 414

Protein sequence:

>414_residues
MNDNQLAPVARPRSPLELLDTVPDSLLRRLKQYSGRLATEAVSAMQERLPFFADLEASQRASVALVVQTAVVNFVEWMHD
PHSDVGYTAQAFELVPQDLTRRIALRQTVDMVRVTMEFFEEVVPLLARSEEQLTALTVGILKYSRDLAFTAATAYADAAE
ARGTWDSRMEASVVDAVVRGDTGPELLSRAAALNWDTTAPATVLVGTPAPGPNGSNSDGDSERASQDVRDTAARHGRAAL
TDVHGTWLVAIVSGQLSPTEKFLKDLLAAFADAPVVIGPTAPMLTAAHRSASEAISGMNAVAGWRGAPRPVLARELLPER
ALMGDASAIVALHTDVMRPLADAGPTLIETLDAYLDCGGAIEACARKLFVHPNTVRYRLKRITDFTGRDPTQPRDAYVLR
VAATVGQLNYPTPH

Sequences:

>Translated_414_residues
MNDNQLAPVARPRSPLELLDTVPDSLLRRLKQYSGRLATEAVSAMQERLPFFADLEASQRASVALVVQTAVVNFVEWMHD
PHSDVGYTAQAFELVPQDLTRRIALRQTVDMVRVTMEFFEEVVPLLARSEEQLTALTVGILKYSRDLAFTAATAYADAAE
ARGTWDSRMEASVVDAVVRGDTGPELLSRAAALNWDTTAPATVLVGTPAPGPNGSNSDGDSERASQDVRDTAARHGRAAL
TDVHGTWLVAIVSGQLSPTEKFLKDLLAAFADAPVVIGPTAPMLTAAHRSASEAISGMNAVAGWRGAPRPVLARELLPER
ALMGDASAIVALHTDVMRPLADAGPTLIETLDAYLDCGGAIEACARKLFVHPNTVRYRLKRITDFTGRDPTQPRDAYVLR
VAATVGQLNYPTPH
>Mature_414_residues
MNDNQLAPVARPRSPLELLDTVPDSLLRRLKQYSGRLATEAVSAMQERLPFFADLEASQRASVALVVQTAVVNFVEWMHD
PHSDVGYTAQAFELVPQDLTRRIALRQTVDMVRVTMEFFEEVVPLLARSEEQLTALTVGILKYSRDLAFTAATAYADAAE
ARGTWDSRMEASVVDAVVRGDTGPELLSRAAALNWDTTAPATVLVGTPAPGPNGSNSDGDSERASQDVRDTAARHGRAAL
TDVHGTWLVAIVSGQLSPTEKFLKDLLAAFADAPVVIGPTAPMLTAAHRSASEAISGMNAVAGWRGAPRPVLARELLPER
ALMGDASAIVALHTDVMRPLADAGPTLIETLDAYLDCGGAIEACARKLFVHPNTVRYRLKRITDFTGRDPTQPRDAYVLR
VAATVGQLNYPTPH

Specific function: Unknown

COG id: COG2508

COG function: function code TQ; Regulator of polyketide synthase expression

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CdaR family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y2242_MYCTU (P63749)

Other databases:

- EMBL:   BX842579
- EMBL:   AE000516
- PIR:   F70778
- RefSeq:   NP_216758.1
- RefSeq:   NP_336772.1
- EnsemblBacteria:   EBMYCT00000003617
- EnsemblBacteria:   EBMYCT00000072902
- GeneID:   888624
- GeneID:   924122
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT2302
- KEGG:   mtu:Rv2242
- TIGR:   MT2302
- TubercuList:   Rv2242
- GeneTree:   EBGT00050000014837
- HOGENOM:   HBG322446
- OMA:   YSREVAF
- ProtClustDB:   CLSK791717
- GO:   GO:0040007

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 44638; Mature: 44638

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDNQLAPVARPRSPLELLDTVPDSLLRRLKQYSGRLATEAVSAMQERLPFFADLEASQR
CCCCCCCCCCCCCCHHHHHHHCHHHHHHHHHHHHCHHHHHHHHHHHHHCCCEECCCCCCC
ASVALVVQTAVVNFVEWMHDPHSDVGYTAQAFELVPQDLTRRIALRQTVDMVRVTMEFFE
CHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVVPLLARSEEQLTALTVGILKYSRDLAFTAATAYADAAEARGTWDSRMEASVVDAVVRG
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCC
DTGPELLSRAAALNWDTTAPATVLVGTPAPGPNGSNSDGDSERASQDVRDTAARHGRAAL
CCCHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHE
TDVHGTWLVAIVSGQLSPTEKFLKDLLAAFADAPVVIGPTAPMLTAAHRSASEAISGMNA
ECCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHHHHHHH
VAGWRGAPRPVLARELLPERALMGDASAIVALHTDVMRPLADAGPTLIETLDAYLDCGGA
HHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHH
IEACARKLFVHPNTVRYRLKRITDFTGRDPTQPRDAYVLRVAATVGQLNYPTPH
HHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCHHHEEHHHHHHCCCCCCCCC
>Mature Secondary Structure
MNDNQLAPVARPRSPLELLDTVPDSLLRRLKQYSGRLATEAVSAMQERLPFFADLEASQR
CCCCCCCCCCCCCCHHHHHHHCHHHHHHHHHHHHCHHHHHHHHHHHHHCCCEECCCCCCC
ASVALVVQTAVVNFVEWMHDPHSDVGYTAQAFELVPQDLTRRIALRQTVDMVRVTMEFFE
CHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVVPLLARSEEQLTALTVGILKYSRDLAFTAATAYADAAEARGTWDSRMEASVVDAVVRG
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCC
DTGPELLSRAAALNWDTTAPATVLVGTPAPGPNGSNSDGDSERASQDVRDTAARHGRAAL
CCCHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHE
TDVHGTWLVAIVSGQLSPTEKFLKDLLAAFADAPVVIGPTAPMLTAAHRSASEAISGMNA
ECCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHHHHHHH
VAGWRGAPRPVLARELLPERALMGDASAIVALHTDVMRPLADAGPTLIETLDAYLDCGGA
HHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHH
IEACARKLFVHPNTVRYRLKRITDFTGRDPTQPRDAYVLRVAATVGQLNYPTPH
HHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCHHHEEHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036