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The map label for this gene is ansP1 [H]

Identifier: 148823338

GI number: 148823338

Start: 2402177

End: 2403646

Strand: Direct

Name: ansP1 [H]

Synonym: TBFG_12159

Alternate gene names: 148823338

Gene position: 2402177-2403646 (Clockwise)

Preceding gene: 148823336

Following gene: 148823347

Centisome position: 54.29

GC content: 62.11

Gene sequence:

>1470_bases
TTGAGCGCGGCCTCACAGCGTGTCGGCGCCTTCGGCGAAGAGGCCGGCTATCACAAAGGCCTCAAGCCCCGACAACTGCA
GATGATCGGGATCGGCGGCGCGATTGGGACCGGCCTGTTCCTCGGCGCCGGCGGCCGGCTTGCCAAGGCCGGACCTGGGT
TGTTCTTGGTGTACGGCGTGTGCGGGGTTTTTGTCTTCCTGATCCTGCGGGCGCTGGGTGAGCTGGTGCTGCACCGTCCG
TCGTCAGGCTCGTTTGTGTCGTATGCACGTGAATTTTTCGGCGAGAAGGCCGCTTACGCGGTGGGCTGGATGTACTTCCT
GCACTGGGCGATGACGTCGATCGTGGACACCACCGCGATCGCCACCTACTTGCAGCGTTGGACGATCTTCACGGTGGTCC
CGCAATGGATTCTTGCCCTGATCGCCTTGACGGTGGTGTTGTCGATGAACCTGATTTCGGTCGAATGGTTCGGCGAGCTG
GAGTTTTGGGCCGCGCTGATCAAGGTTCTCGCGCTGATGGCGTTCCTAGTGGTGGGAACCGTTTTTTTGGCCGGGCGATA
CCCCGTCGACGGCCACAGCACCGGATTGAGCTTGTGGAACAACCATGGCGGGCTGTTCCCGACAAGCTGGCTGCCGCTGC
TGATCGTTACCTCGGGAGTGGTGTTCGCGTACTCAGCAGTCGAATTGGTAGGGACGGCGGCCGGGGAGACCGCCGAGCCG
GAGAAGATCATGCCGCGGGCGATCAATTCGGTGGTCGCTCGCATCGCGATCTTTTATGTCGGGTCGGTGGCCCTGCTAGC
GCTGTTGCTGCCGTATACCGCCTACAAGGCCGGCGAGAGCCCGTTCGTCACGTTCTTTTCCAAAATCGGTTTCCACGGTG
CCGGTGACTTGATGAACATCGTTGTGCTTACCGCCGCGCTGTCGAGCCTGAACGCGGGGCTGTATTCGACCGGCCGCGTC
ATGCATTCGATCGCGATGAGCGGCAGCGCCCCAAGGTTCACCGCGCGAATGTCGAAAAGCGGTGTGCCCTACGGCGGGAT
CGTGTTGACCGCGGTCATCACCCTGTTCGGTGTCGCGCTGAACGCCTTCAAGCCCGGTGAAGCCTTCGAGATTGTGCTCA
ACATGTCCGCGCTGGGCATCATCGCGGGTTGGGCCACCATCGTGCTGTGTCAGCTTCGACTTCACAAGCTGGCCAACGCC
GGGATCATGCAGCGGCCGCGGTTCCGCATGCCCTTCTCCCCCTACAGCGGCTACCTCACCTTGCTCTTCTTGCTTGTCGT
GCTGGTTACGATGGCGTCCGACAAACCGATCGGCACCTGGACGGTGGCGACACTGATTATTGTCATTCCGGCCCTGACCG
CAGGCTGGTACCTGGTACGCAAGCGTGTCATGGCCGTCGCCCGCGAAAGGCTGGGTCATACCGGGCCATTTCCGGCGGTC
GCCAACCCGCCCGTGAGGTCAAGAGACTGA

Upstream 100 bases:

>100_bases
TTGCCGCCACCCCTAGAGTGGGCGAGGATCGCAAGAGCAAATTCCGCGCCGGTAGGACAACGATAGGACCGCCATTACGA
AGCCGCCCGAGACTCCTGAA

Downstream 100 bases:

>100_bases
TGCTTCGAAGAGGTGAATCGATCATCCGCAACCGTTACGCCAGTAAGCCACCACTGTACGGAATGGCAATGGTCTTCTTG
GCCATGGCCGTCGTCGCCGT

Product: L-asparagine permease ansP1

Products: Proton [Cytoplasm]; L-asparagine [Cytoplasm] [C]

Alternate protein names: L-asparagine transport protein 1 [H]

Number of amino acids: Translated: 489; Mature: 488

Protein sequence:

>489_residues
MSAASQRVGAFGEEAGYHKGLKPRQLQMIGIGGAIGTGLFLGAGGRLAKAGPGLFLVYGVCGVFVFLILRALGELVLHRP
SSGSFVSYAREFFGEKAAYAVGWMYFLHWAMTSIVDTTAIATYLQRWTIFTVVPQWILALIALTVVLSMNLISVEWFGEL
EFWAALIKVLALMAFLVVGTVFLAGRYPVDGHSTGLSLWNNHGGLFPTSWLPLLIVTSGVVFAYSAVELVGTAAGETAEP
EKIMPRAINSVVARIAIFYVGSVALLALLLPYTAYKAGESPFVTFFSKIGFHGAGDLMNIVVLTAALSSLNAGLYSTGRV
MHSIAMSGSAPRFTARMSKSGVPYGGIVLTAVITLFGVALNAFKPGEAFEIVLNMSALGIIAGWATIVLCQLRLHKLANA
GIMQRPRFRMPFSPYSGYLTLLFLLVVLVTMASDKPIGTWTVATLIIVIPALTAGWYLVRKRVMAVARERLGHTGPFPAV
ANPPVRSRD

Sequences:

>Translated_489_residues
MSAASQRVGAFGEEAGYHKGLKPRQLQMIGIGGAIGTGLFLGAGGRLAKAGPGLFLVYGVCGVFVFLILRALGELVLHRP
SSGSFVSYAREFFGEKAAYAVGWMYFLHWAMTSIVDTTAIATYLQRWTIFTVVPQWILALIALTVVLSMNLISVEWFGEL
EFWAALIKVLALMAFLVVGTVFLAGRYPVDGHSTGLSLWNNHGGLFPTSWLPLLIVTSGVVFAYSAVELVGTAAGETAEP
EKIMPRAINSVVARIAIFYVGSVALLALLLPYTAYKAGESPFVTFFSKIGFHGAGDLMNIVVLTAALSSLNAGLYSTGRV
MHSIAMSGSAPRFTARMSKSGVPYGGIVLTAVITLFGVALNAFKPGEAFEIVLNMSALGIIAGWATIVLCQLRLHKLANA
GIMQRPRFRMPFSPYSGYLTLLFLLVVLVTMASDKPIGTWTVATLIIVIPALTAGWYLVRKRVMAVARERLGHTGPFPAV
ANPPVRSRD
>Mature_488_residues
SAASQRVGAFGEEAGYHKGLKPRQLQMIGIGGAIGTGLFLGAGGRLAKAGPGLFLVYGVCGVFVFLILRALGELVLHRPS
SGSFVSYAREFFGEKAAYAVGWMYFLHWAMTSIVDTTAIATYLQRWTIFTVVPQWILALIALTVVLSMNLISVEWFGELE
FWAALIKVLALMAFLVVGTVFLAGRYPVDGHSTGLSLWNNHGGLFPTSWLPLLIVTSGVVFAYSAVELVGTAAGETAEPE
KIMPRAINSVVARIAIFYVGSVALLALLLPYTAYKAGESPFVTFFSKIGFHGAGDLMNIVVLTAALSSLNAGLYSTGRVM
HSIAMSGSAPRFTARMSKSGVPYGGIVLTAVITLFGVALNAFKPGEAFEIVLNMSALGIIAGWATIVLCQLRLHKLANAG
IMQRPRFRMPFSPYSGYLTLLFLLVVLVTMASDKPIGTWTVATLIIVIPALTAGWYLVRKRVMAVARERLGHTGPFPAVA
NPPVRSRD

Specific function: Unknown

COG id: COG1113

COG function: function code E; Gamma-aminobutyrate permease and related permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family [H]

Homologues:

Organism=Homo sapiens, GI181337167, Length=342, Percent_Identity=24.5614035087719, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI87081915, Length=463, Percent_Identity=60.2591792656587, Blast_Score=535, Evalue=1e-153,
Organism=Escherichia coli, GI1786789, Length=425, Percent_Identity=36.4705882352941, Blast_Score=283, Evalue=2e-77,
Organism=Escherichia coli, GI1786302, Length=425, Percent_Identity=36.7058823529412, Blast_Score=280, Evalue=1e-76,
Organism=Escherichia coli, GI1790653, Length=466, Percent_Identity=34.9785407725322, Blast_Score=278, Evalue=7e-76,
Organism=Escherichia coli, GI48994972, Length=420, Percent_Identity=37.6190476190476, Blast_Score=270, Evalue=2e-73,
Organism=Escherichia coli, GI1786602, Length=456, Percent_Identity=33.7719298245614, Blast_Score=258, Evalue=5e-70,
Organism=Escherichia coli, GI87081708, Length=426, Percent_Identity=33.5680751173709, Blast_Score=241, Evalue=6e-65,
Organism=Escherichia coli, GI1788480, Length=434, Percent_Identity=33.8709677419355, Blast_Score=235, Evalue=6e-63,
Organism=Escherichia coli, GI1789017, Length=425, Percent_Identity=32.2352941176471, Blast_Score=224, Evalue=1e-59,
Organism=Saccharomyces cerevisiae, GI6324061, Length=445, Percent_Identity=32.5842696629214, Blast_Score=220, Evalue=3e-58,
Organism=Saccharomyces cerevisiae, GI6320772, Length=442, Percent_Identity=30.9954751131222, Blast_Score=197, Evalue=4e-51,
Organism=Saccharomyces cerevisiae, GI6324059, Length=453, Percent_Identity=31.5673289183223, Blast_Score=181, Evalue=2e-46,
Organism=Saccharomyces cerevisiae, GI6322892, Length=442, Percent_Identity=30.316742081448, Blast_Score=177, Evalue=3e-45,
Organism=Saccharomyces cerevisiae, GI6324990, Length=440, Percent_Identity=28.1818181818182, Blast_Score=175, Evalue=1e-44,
Organism=Saccharomyces cerevisiae, GI6324924, Length=452, Percent_Identity=27.4336283185841, Blast_Score=162, Evalue=1e-40,
Organism=Saccharomyces cerevisiae, GI6324553, Length=447, Percent_Identity=29.082774049217, Blast_Score=157, Evalue=3e-39,
Organism=Saccharomyces cerevisiae, GI6321053, Length=426, Percent_Identity=27.2300469483568, Blast_Score=157, Evalue=3e-39,
Organism=Saccharomyces cerevisiae, GI6321629, Length=419, Percent_Identity=27.6849642004773, Blast_Score=155, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6320717, Length=398, Percent_Identity=26.1306532663317, Blast_Score=150, Evalue=3e-37,
Organism=Saccharomyces cerevisiae, GI6322967, Length=440, Percent_Identity=27.2727272727273, Blast_Score=144, Evalue=4e-35,
Organism=Saccharomyces cerevisiae, GI6319824, Length=414, Percent_Identity=25.1207729468599, Blast_Score=141, Evalue=2e-34,
Organism=Saccharomyces cerevisiae, GI6324981, Length=391, Percent_Identity=29.4117647058824, Blast_Score=132, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6319543, Length=395, Percent_Identity=26.5822784810127, Blast_Score=124, Evalue=4e-29,
Organism=Saccharomyces cerevisiae, GI6320251, Length=392, Percent_Identity=23.9795918367347, Blast_Score=121, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6319608, Length=442, Percent_Identity=25.5656108597285, Blast_Score=117, Evalue=4e-27,
Organism=Saccharomyces cerevisiae, GI6319542, Length=407, Percent_Identity=24.0786240786241, Blast_Score=111, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6320364, Length=486, Percent_Identity=23.6625514403292, Blast_Score=85, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004840 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 52448; Mature: 52317

Theoretical pI: Translated: 10.23; Mature: 10.23

Prosite motif: PS00218 AMINO_ACID_PERMEASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAASQRVGAFGEEAGYHKGLKPRQLQMIGIGGAIGTGLFLGAGGRLAKAGPGLFLVYGV
CCCCHHHHCCCCHHCCCCCCCCCCEEEEEECCHHHHHHHHCCCCCCCCCCCCCHHHHHHH
CGVFVFLILRALGELVLHRPSSGSFVSYAREFFGEKAAYAVGWMYFLHWAMTSIVDTTAI
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
ATYLQRWTIFTVVPQWILALIALTVVLSMNLISVEWFGELEFWAALIKVLALMAFLVVGT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEHHCCHHHHHHHHHHHHHHHHHHHHH
VFLAGRYPVDGHSTGLSLWNNHGGLFPTSWLPLLIVTSGVVFAYSAVELVGTAAGETAEP
HHHHCCCCCCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
EKIMPRAINSVVARIAIFYVGSVALLALLLPYTAYKAGESPFVTFFSKIGFHGAGDLMNI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHH
VVLTAALSSLNAGLYSTGRVMHSIAMSGSAPRFTARMSKSGVPYGGIVLTAVITLFGVAL
HHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
NAFKPGEAFEIVLNMSALGIIAGWATIVLCQLRLHKLANAGIMQRPRFRMPFSPYSGYLT
HCCCCCCHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHH
LLFLLVVLVTMASDKPIGTWTVATLIIVIPALTAGWYLVRKRVMAVARERLGHTGPFPAV
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
ANPPVRSRD
CCCCCCCCC
>Mature Secondary Structure 
SAASQRVGAFGEEAGYHKGLKPRQLQMIGIGGAIGTGLFLGAGGRLAKAGPGLFLVYGV
CCCHHHHCCCCHHCCCCCCCCCCEEEEEECCHHHHHHHHCCCCCCCCCCCCCHHHHHHH
CGVFVFLILRALGELVLHRPSSGSFVSYAREFFGEKAAYAVGWMYFLHWAMTSIVDTTAI
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
ATYLQRWTIFTVVPQWILALIALTVVLSMNLISVEWFGELEFWAALIKVLALMAFLVVGT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEHHCCHHHHHHHHHHHHHHHHHHHHH
VFLAGRYPVDGHSTGLSLWNNHGGLFPTSWLPLLIVTSGVVFAYSAVELVGTAAGETAEP
HHHHCCCCCCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
EKIMPRAINSVVARIAIFYVGSVALLALLLPYTAYKAGESPFVTFFSKIGFHGAGDLMNI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHH
VVLTAALSSLNAGLYSTGRVMHSIAMSGSAPRFTARMSKSGVPYGGIVLTAVITLFGVAL
HHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
NAFKPGEAFEIVLNMSALGIIAGWATIVLCQLRLHKLANAGIMQRPRFRMPFSPYSGYLT
HCCCCCCHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHH
LLFLLVVLVTMASDKPIGTWTVATLIIVIPALTAGWYLVRKRVMAVARERLGHTGPFPAV
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
ANPPVRSRD
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-asparagine [Periplasm]; Proton [Periplasm] [C]

Specific reaction: L-asparagine [Periplasm] + Proton [Periplasm] = Proton [Cytoplasm] + L-asparagine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]