Click here to switch to the map view.

The map label for this gene is yebQ [C]

Identifier: 148823088

GI number: 148823088

Start: 2134095

End: 2136158

Strand: Direct

Name: yebQ [C]

Synonym: TBFG_11905

Alternate gene names: 148823088

Gene position: 2134095-2136158 (Clockwise)

Preceding gene: 148823087

Following gene: 148823089

Centisome position: 48.23

GC content: 64.39

Gene sequence:

>2064_bases
ATGGCGGGCCCCACAGCACCGACCACTGCCCCCACCGCAATCCGAGCCGGTGGCCCGCTGCTCAGTCCGGTGCGACGCAA
CATTATTTTCACCGCACTTGTGTTCGGGGTGCTGGTCGCTGCGACCGGCCAAACCATCGTTGTGCCCGCATTGCCGACGA
TCGTCGCCGAGCTGGGCAGCACCGTTGACCAGTCGTGGGCGGTCACCAGCTATCTGCTGGGGGGAACTGTCGTGGTTGTG
GTGGCTGGCAAGCTCGGTGATCTGCTCGGCCGCAACAGGGTGCTGCTAGGCTCCGTCGTGGTCTTCGTCGTTGGCTCTGT
GCTGTGCGGGTTATCGCAGACGATGACCATGCTGGCGATCTCTCGCGCACTGCAGGGCGTCGGTGCCGGTGCGATTTCCG
TCACCGCCTACGCGCTGGCCGCTGAGGTGGTCCCACTGCGGGACCGTGGCCGCTACCAGGGCGTCTTAGGTGCGGTGTTC
GGTGTCAACACGGTCACCGGTCCGCTGCTGGGGGGCTGGCTCACCGACTATCTGAGCTGGCGGTGGGCGTTTTGGATCAA
CGTGCCGGTTTCGATCGCGGTGCTGACAGTGGCGGCAACCGCCGTCCCTGCGTTGGCCCGACCGCCCAAACCGGTCATCG
ACTACCTTGGGATCCTGGTCATCGCTGTGGCCACGACCGCTTTGATCATGGCCACAAGTTGGGGCGGAACCACCTACGCC
TGGGGCTCAGCGACCATTGTCGGGCTGTTGATCGGGGCCGCAGTGGCGCTGGGTTTCTTCGTGTGGCTGGAGGGCCGCGC
CGCTGCGGCCATCCTGCCGCCCAGGCTGTTTGGCAGCCCAGTATTTGCCGTGTGCTGCGTCCTGTCCTTCGTGGTCGGAT
TCGCGATGCTGGGTGCACTGACCTTCGTACCGATCTATCTGGGGTACGTGGACGGCGCGTCGGCGACCGCGTCAGGTCTG
CGCACGTTGCCGATGGTGATCGGCCTGCTGATCGCCTCGACCGGGACGGGTGTCCTGGTCGGCCGGACGGGCCGCTACAA
GATCTTCCCGGTCGCGGGGATGGCGCTGATGGCGGTTGCGTTCCTGCTGATGTCGCAGATGGACGAGTGGACGCCACCGC
TGCTGCAATCGCTGTACCTGGTCGTCCTAGGTGCCGGCATCGGATTGTCCATGCAGGTGCTCGTTCTCATCGTGCAGAAC
ACGTCGTCTTTCGAAGACCTCGGCGTCGCAACATCGGGTGTGACCTTCTTCCGGGTGGTCGGCGCCTCGTTTGGTACCGC
AACATTCGGTGCGTTGTTCGTAAACTTCCTGGACCGAAGACTCGGTTCCGCGCTGACGTCGGGCGCCGTGCCTGTCCCGG
CAGTGCCATCTCCGGCTGTCTTGCATCAGCTGCCCCAGAGCATGGCCGCCCCGATCGTGCGGGCATATGCCGAGTCGCTC
ACCCAGGTGTTCCTTTGCGCGGTCTCGGTCACGGTGGTCGGTTTCATCCTGGCGCTGTTGCTGCGAGAGGTACCGCTCAC
CGACATCCACGATGACGCCGACGACCTCGGCGACGGGTTCGGTGTGCCCAGAGCCGAATCGCCGGAGGATGTGTTGGAAA
TCGCGGTTCGGCGTATGCTGCCGAACGGGGTGCGACTGCGCGATATTGCGACACAACCCGGTTGCGGACTCGGCGTCGCC
GAGCTGTGGGCCCTTCTGCGGATCTATCAATACCAGCGGCTGTTCGAGGCAGTACGGCTGACCGATATCGGTAGACACCT
GCACGTGCCCTATCAGGTCTTTGAACCCGTCTTCGACCGTCTGGTCCAGACCGGCTACGCGGCACGCGACGGCGACATCT
TGACGCTAACCCCGTCCGGGCACCGTCAGGTCGACTCCCTCGCAGTTTTGATCCGTCAGTGGCTGCTCGACCACTTGGCC
GTGGCGCCCGGCTTGAAGCGACAGCCAGACCACCAATTCGAAGCCGCTCTGCAGCACGTCACCGACGCGGTGCTCGTTCA
ACGAGACTGGTATGAAGATCTGGGCGACCTGTCGGAATCACGCCAACTCGCGGCTACAACGTAG

Upstream 100 bases:

>100_bases
TCGCCCACCGACCTGATGCCCGCTTGAGGATTCTCCGATACCACTCCGGGCGCCGCTGACAAGCTCTAGCATCGACTCGA
ACAGCGATGGGAGGGCGGAT

Downstream 100 bases:

>100_bases
CGATGCTTGCCGCGCGTAGCCGCGCGAGCTGATCCGCGCTGCAGAATGACTGCCATGACAGCCACACCGCTTGCCGCGGC
CGCGATCGCCCAATTGGAGG

Product: integral membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 687; Mature: 686

Protein sequence:

>687_residues
MAGPTAPTTAPTAIRAGGPLLSPVRRNIIFTALVFGVLVAATGQTIVVPALPTIVAELGSTVDQSWAVTSYLLGGTVVVV
VAGKLGDLLGRNRVLLGSVVVFVVGSVLCGLSQTMTMLAISRALQGVGAGAISVTAYALAAEVVPLRDRGRYQGVLGAVF
GVNTVTGPLLGGWLTDYLSWRWAFWINVPVSIAVLTVAATAVPALARPPKPVIDYLGILVIAVATTALIMATSWGGTTYA
WGSATIVGLLIGAAVALGFFVWLEGRAAAAILPPRLFGSPVFAVCCVLSFVVGFAMLGALTFVPIYLGYVDGASATASGL
RTLPMVIGLLIASTGTGVLVGRTGRYKIFPVAGMALMAVAFLLMSQMDEWTPPLLQSLYLVVLGAGIGLSMQVLVLIVQN
TSSFEDLGVATSGVTFFRVVGASFGTATFGALFVNFLDRRLGSALTSGAVPVPAVPSPAVLHQLPQSMAAPIVRAYAESL
TQVFLCAVSVTVVGFILALLLREVPLTDIHDDADDLGDGFGVPRAESPEDVLEIAVRRMLPNGVRLRDIATQPGCGLGVA
ELWALLRIYQYQRLFEAVRLTDIGRHLHVPYQVFEPVFDRLVQTGYAARDGDILTLTPSGHRQVDSLAVLIRQWLLDHLA
VAPGLKRQPDHQFEAALQHVTDAVLVQRDWYEDLGDLSESRQLAATT

Sequences:

>Translated_687_residues
MAGPTAPTTAPTAIRAGGPLLSPVRRNIIFTALVFGVLVAATGQTIVVPALPTIVAELGSTVDQSWAVTSYLLGGTVVVV
VAGKLGDLLGRNRVLLGSVVVFVVGSVLCGLSQTMTMLAISRALQGVGAGAISVTAYALAAEVVPLRDRGRYQGVLGAVF
GVNTVTGPLLGGWLTDYLSWRWAFWINVPVSIAVLTVAATAVPALARPPKPVIDYLGILVIAVATTALIMATSWGGTTYA
WGSATIVGLLIGAAVALGFFVWLEGRAAAAILPPRLFGSPVFAVCCVLSFVVGFAMLGALTFVPIYLGYVDGASATASGL
RTLPMVIGLLIASTGTGVLVGRTGRYKIFPVAGMALMAVAFLLMSQMDEWTPPLLQSLYLVVLGAGIGLSMQVLVLIVQN
TSSFEDLGVATSGVTFFRVVGASFGTATFGALFVNFLDRRLGSALTSGAVPVPAVPSPAVLHQLPQSMAAPIVRAYAESL
TQVFLCAVSVTVVGFILALLLREVPLTDIHDDADDLGDGFGVPRAESPEDVLEIAVRRMLPNGVRLRDIATQPGCGLGVA
ELWALLRIYQYQRLFEAVRLTDIGRHLHVPYQVFEPVFDRLVQTGYAARDGDILTLTPSGHRQVDSLAVLIRQWLLDHLA
VAPGLKRQPDHQFEAALQHVTDAVLVQRDWYEDLGDLSESRQLAATT
>Mature_686_residues
AGPTAPTTAPTAIRAGGPLLSPVRRNIIFTALVFGVLVAATGQTIVVPALPTIVAELGSTVDQSWAVTSYLLGGTVVVVV
AGKLGDLLGRNRVLLGSVVVFVVGSVLCGLSQTMTMLAISRALQGVGAGAISVTAYALAAEVVPLRDRGRYQGVLGAVFG
VNTVTGPLLGGWLTDYLSWRWAFWINVPVSIAVLTVAATAVPALARPPKPVIDYLGILVIAVATTALIMATSWGGTTYAW
GSATIVGLLIGAAVALGFFVWLEGRAAAAILPPRLFGSPVFAVCCVLSFVVGFAMLGALTFVPIYLGYVDGASATASGLR
TLPMVIGLLIASTGTGVLVGRTGRYKIFPVAGMALMAVAFLLMSQMDEWTPPLLQSLYLVVLGAGIGLSMQVLVLIVQNT
SSFEDLGVATSGVTFFRVVGASFGTATFGALFVNFLDRRLGSALTSGAVPVPAVPSPAVLHQLPQSMAAPIVRAYAESLT
QVFLCAVSVTVVGFILALLLREVPLTDIHDDADDLGDGFGVPRAESPEDVLEIAVRRMLPNGVRLRDIATQPGCGLGVAE
LWALLRIYQYQRLFEAVRLTDIGRHLHVPYQVFEPVFDRLVQTGYAARDGDILTLTPSGHRQVDSLAVLIRQWLLDHLAV
APGLKRQPDHQFEAALQHVTDAVLVQRDWYEDLGDLSESRQLAATT

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. TCR/tet family

Homologues:

Organism=Escherichia coli, GI87081983, Length=422, Percent_Identity=27.4881516587678, Blast_Score=113, Evalue=4e-26,
Organism=Escherichia coli, GI1789042, Length=300, Percent_Identity=28.3333333333333, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1788710, Length=407, Percent_Identity=26.7813267813268, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1788392, Length=337, Percent_Identity=29.673590504451, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI1790146, Length=176, Percent_Identity=30.6818181818182, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1790195, Length=167, Percent_Identity=32.9341317365269, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI1788509, Length=141, Percent_Identity=31.2056737588652, Blast_Score=71, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6319770, Length=466, Percent_Identity=25.9656652360515, Blast_Score=124, Evalue=4e-29,
Organism=Saccharomyces cerevisiae, GI6322958, Length=546, Percent_Identity=21.0622710622711, Blast_Score=112, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6323735, Length=327, Percent_Identity=26.2996941896024, Blast_Score=103, Evalue=8e-23,
Organism=Saccharomyces cerevisiae, GI6325455, Length=234, Percent_Identity=26.4957264957265, Blast_Score=94, Evalue=7e-20,
Organism=Saccharomyces cerevisiae, GI6321663, Length=145, Percent_Identity=29.6551724137931, Blast_Score=89, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6324954, Length=374, Percent_Identity=22.9946524064171, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y1877_MYCTU (O07753)

Other databases:

- EMBL:   BX842578
- EMBL:   AE000516
- PIR:   B70515
- RefSeq:   NP_216393.1
- RefSeq:   NP_336384.1
- ProteinModelPortal:   O07753
- EnsemblBacteria:   EBMYCT00000001785
- EnsemblBacteria:   EBMYCT00000069797
- GeneID:   885654
- GeneID:   923653
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT1926
- KEGG:   mtu:Rv1877
- TIGR:   MT1926
- TubercuList:   Rv1877
- GeneTree:   EBGT00050000014781
- HOGENOM:   HBG679341
- OMA:   ATSWGGS
- ProtClustDB:   CLSK791452
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829
- InterPro:   IPR001958
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- PRINTS:   PR01035

Pfam domain/function: PF07690 MFS_1; SSF103473 MFS_gen_substrate_transporter

EC number: NA

Molecular weight: Translated: 72355; Mature: 72223

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: PS50850 MFS; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1aedc014)-; HASH(0x1b107f70)-; HASH(0x1b01f374)-; HASH(0x1ae396ac)-; HASH(0x181f3538)-; HASH(0x1a49d38c)-; HASH(0x1ac3ef58)-; HASH(0x1af5e4d4)-; HASH(0x1b1e7b64)-; HASH(0x1b21469c)-; HASH(0x1aa8eb00)-; HASH(0x1a34ae9c)-; HASH(0x1ab026f4)-; HASH(0x1b0a9478)-;

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGPTAPTTAPTAIRAGGPLLSPVRRNIIFTALVFGVLVAATGQTIVVPALPTIVAELGS
CCCCCCCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHCC
TVDQSWAVTSYLLGGTVVVVVAGKLGDLLGRNRVLLGSVVVFVVGSVLCGLSQTMTMLAI
HHHHHHHHHHHHHCCEEEEEEEHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
SRALQGVGAGAISVTAYALAAEVVPLRDRGRYQGVLGAVFGVNTVTGPLLGGWLTDYLSW
HHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RWAFWINVPVSIAVLTVAATAVPALARPPKPVIDYLGILVIAVATTALIMATSWGGTTYA
EEEEEEECCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
WGSATIVGLLIGAAVALGFFVWLEGRAAAAILPPRLFGSPVFAVCCVLSFVVGFAMLGAL
CHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCHHHHCCHHHHHHHHHHHHHHHHHHHHH
TFVPIYLGYVDGASATASGLRTLPMVIGLLIASTGTGVLVGRTGRYKIFPVAGMALMAVA
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEHHHHHHHHHH
FLLMSQMDEWTPPLLQSLYLVVLGAGIGLSMQVLVLIVQNTSSFEDLGVATSGVTFFRVV
HHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHCCCCCCHHHHHHH
GASFGTATFGALFVNFLDRRLGSALTSGAVPVPAVPSPAVLHQLPQSMAAPIVRAYAESL
HCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
TQVFLCAVSVTVVGFILALLLREVPLTDIHDDADDLGDGFGVPRAESPEDVLEIAVRRML
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHC
PNGVRLRDIATQPGCGLGVAELWALLRIYQYQRLFEAVRLTDIGRHLHVPYQVFEPVFDR
CCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCHHHHHHHHHH
LVQTGYAARDGDILTLTPSGHRQVDSLAVLIRQWLLDHLAVAPGLKRQPDHQFEAALQHV
HHHCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
TDAVLVQRDWYEDLGDLSESRQLAATT
HHHHHHHHHHHHHHHHHHHCCCCCCCH
>Mature Secondary Structure 
AGPTAPTTAPTAIRAGGPLLSPVRRNIIFTALVFGVLVAATGQTIVVPALPTIVAELGS
CCCCCCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHCC
TVDQSWAVTSYLLGGTVVVVVAGKLGDLLGRNRVLLGSVVVFVVGSVLCGLSQTMTMLAI
HHHHHHHHHHHHHCCEEEEEEEHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
SRALQGVGAGAISVTAYALAAEVVPLRDRGRYQGVLGAVFGVNTVTGPLLGGWLTDYLSW
HHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RWAFWINVPVSIAVLTVAATAVPALARPPKPVIDYLGILVIAVATTALIMATSWGGTTYA
EEEEEEECCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
WGSATIVGLLIGAAVALGFFVWLEGRAAAAILPPRLFGSPVFAVCCVLSFVVGFAMLGAL
CHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCHHHHCCHHHHHHHHHHHHHHHHHHHHH
TFVPIYLGYVDGASATASGLRTLPMVIGLLIASTGTGVLVGRTGRYKIFPVAGMALMAVA
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEHHHHHHHHHH
FLLMSQMDEWTPPLLQSLYLVVLGAGIGLSMQVLVLIVQNTSSFEDLGVATSGVTFFRVV
HHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHCCCCCCHHHHHHH
GASFGTATFGALFVNFLDRRLGSALTSGAVPVPAVPSPAVLHQLPQSMAAPIVRAYAESL
HCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
TQVFLCAVSVTVVGFILALLLREVPLTDIHDDADDLGDGFGVPRAESPEDVLEIAVRRML
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHC
PNGVRLRDIATQPGCGLGVAELWALLRIYQYQRLFEAVRLTDIGRHLHVPYQVFEPVFDR
CCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCHHHHHHHHHH
LVQTGYAARDGDILTLTPSGHRQVDSLAVLIRQWLLDHLAVAPGLKRQPDHQFEAALQHV
HHHCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
TDAVLVQRDWYEDLGDLSESRQLAATT
HHHHHHHHHHHHHHHHHHHCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036