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The map label for this gene is PE_PGRS33 [H]

Identifier: 148823031

GI number: 148823031

Start: 2069430

End: 2070986

Strand: Reverse

Name: PE_PGRS33 [H]

Synonym: TBFG_11848

Alternate gene names: 148823031

Gene position: 2070986-2069430 (Counterclockwise)

Preceding gene: 148823032

Following gene: 148823026

Centisome position: 46.81

GC content: 77.97

Gene sequence:

>1557_bases
GTGACCAGGCGATCGGTAGCGGCCCCGCGCCGGGGCCACAGGGTGTTGACGAGGTGCCAGATGTCATTTGTGGTCACGAT
CCCGGAGGCGCTAGCGGCGGTGGCGACCGATTTGGCGGGTATCGGGTCGACGATCGGCACCGCCAACGCGGCCGCCGCGG
TCCCGACCACGACGGTGTTGGCCGCCGCCGCCGATGAGGTGTCGGCGGCGATGGCGGCATTGTTCTCCGGACACGCCCAG
GCCTATCAGGCGCTGAGCGCCCAGGCGGCGCTGTTTCACGAGCAGTTCGTGCGGGCGCTCACCGCCGGGGCGGGCTCGTA
TGCGGCCGCCGAGGCCGCCAGCGCGGCCCCGCTAGAGGGTGTGCTCGACGTGATCAACGCCCCCGCCCTGGCGCTGTTGG
GGCGCCCACTGATCGGTAACGGAGCCAACGGGGCCCCGGGGACCGGGGCAAACGGCGGCGACGGCGGAATCTTGATCGGC
AACGGCGGGGCCGGCGGCTCCGGCGCGGCCGGCATGCCCGGGGGCAACGGCGGAGCCGCTGGCCTGTTCGGCAACGGCGG
GGCCGGCGGCGCCGGGGGGAACGTAGCGTCCGGCACCGCAGGGTTCGGCGGGGCCGGCGGGGCCGGCGGGCTGCTCTACG
GCGCCGGCGGGGCCGGCGGCGCCGGCGGACGCGCCGGTGGTGGGGTGGGCGGTATTGGTGGGGCCGGCGGGGCCGGCGGC
AATGGCGGGCTGCTGTTCGGCGCCGGCGGGGCCGGCGGCGTCGGCGGACTCGCGGCTGACGCCGGTGACGGCGGGGCCGG
CGGAGACGGCGGGTTGTTCTTCGGCGTGGGCGGTGCCGGCGGGGCCGGCGGCACCGGCACTAATGTCACCGGCGGTGCCG
GCGGGGCCGGCGGCAATGGCGGGCTCCTGTTCGGCGCCGGCGGGGTGGGCGGTGTTGGCGGTGACGGTGTGGCATTCCTG
GGCACCGCCCCCGGCGGGCCCGGTGGTGCCGGCGGGGCCGGTGGGCTGTTCGGCGTCGGTGGGGCCGGCGGCGCCGGCGG
AATCGGATTGGTCGGGAACGGCGGTGCCGGGGGGTCCGGCGGGTCCGCCCTGCTCTGGGGCGACGGCGGTGCCGGCGGCG
CGGGTGGGGTCGGGTCCACTACCGGCGGTGCCGGCGGGGCGGGCGGCAACGCCGGCCTGCTGGTAGGCGCCGGCGGGGCC
GGCGGCGCCGGCGCACTCGGCGGTGGCGCTACCGGGGTGGGCGGCGCCGGCGGAAACGGCGGCACTGCGGGCCTGCTGTT
TGGTGCCGGCGGCGCCGGCGGATTCGGCTTCGGCGGTGCCGGGGGCGCCGGTGGGCTCGGCGGCAAAGCCGGGCTGATCG
GCGACGGCGGTGACGGCGGCGCCGGAGGAAACGGCACCGGTGCCAAGGGCGGTGACGGCGGCGCTGGCGGCGGTGCCATC
CTGGTCGGCAACGGCGGCAACGGCGGCAACGCCGGGAGTGGCACACCTAACGGCAGCGCGGGCACCGGCGGTGCCGGCGG
GCTGTTGGGTAAGAACGGGATGAACGGGTTACCGTAG

Upstream 100 bases:

>100_bases
TCGAGGCGGCGCCCGCCGAAGTGTAAGCCGGGACGAGCTTCCCAAATCGGCGTGGCCGCTTCCGTGATCGCGATACGCTG
AATCCGTCGATCTCTGGGGA

Downstream 100 bases:

>100_bases
CCGGGAGGCCGGCTACCGCGCTCCCGGCGTCTTACCTGAAGCCGCGCTGCGACTGTGAATCTCACGACGCCTTGTCGGCG
TGTCGCGTCGCAGGATTCCC

Product: PE-PGRS family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 518; Mature: 517

Protein sequence:

>518_residues
MTRRSVAAPRRGHRVLTRCQMSFVVTIPEALAAVATDLAGIGSTIGTANAAAAVPTTTVLAAAADEVSAAMAALFSGHAQ
AYQALSAQAALFHEQFVRALTAGAGSYAAAEAASAAPLEGVLDVINAPALALLGRPLIGNGANGAPGTGANGGDGGILIG
NGGAGGSGAAGMPGGNGGAAGLFGNGGAGGAGGNVASGTAGFGGAGGAGGLLYGAGGAGGAGGRAGGGVGGIGGAGGAGG
NGGLLFGAGGAGGVGGLAADAGDGGAGGDGGLFFGVGGAGGAGGTGTNVTGGAGGAGGNGGLLFGAGGVGGVGGDGVAFL
GTAPGGPGGAGGAGGLFGVGGAGGAGGIGLVGNGGAGGSGGSALLWGDGGAGGAGGVGSTTGGAGGAGGNAGLLVGAGGA
GGAGALGGGATGVGGAGGNGGTAGLLFGAGGAGGFGFGGAGGAGGLGGKAGLIGDGGDGGAGGNGTGAKGGDGGAGGGAI
LVGNGGNGGNAGSGTPNGSAGTGGAGGLLGKNGMNGLP

Sequences:

>Translated_518_residues
MTRRSVAAPRRGHRVLTRCQMSFVVTIPEALAAVATDLAGIGSTIGTANAAAAVPTTTVLAAAADEVSAAMAALFSGHAQ
AYQALSAQAALFHEQFVRALTAGAGSYAAAEAASAAPLEGVLDVINAPALALLGRPLIGNGANGAPGTGANGGDGGILIG
NGGAGGSGAAGMPGGNGGAAGLFGNGGAGGAGGNVASGTAGFGGAGGAGGLLYGAGGAGGAGGRAGGGVGGIGGAGGAGG
NGGLLFGAGGAGGVGGLAADAGDGGAGGDGGLFFGVGGAGGAGGTGTNVTGGAGGAGGNGGLLFGAGGVGGVGGDGVAFL
GTAPGGPGGAGGAGGLFGVGGAGGAGGIGLVGNGGAGGSGGSALLWGDGGAGGAGGVGSTTGGAGGAGGNAGLLVGAGGA
GGAGALGGGATGVGGAGGNGGTAGLLFGAGGAGGFGFGGAGGAGGLGGKAGLIGDGGDGGAGGNGTGAKGGDGGAGGGAI
LVGNGGNGGNAGSGTPNGSAGTGGAGGLLGKNGMNGLP
>Mature_517_residues
TRRSVAAPRRGHRVLTRCQMSFVVTIPEALAAVATDLAGIGSTIGTANAAAAVPTTTVLAAAADEVSAAMAALFSGHAQA
YQALSAQAALFHEQFVRALTAGAGSYAAAEAASAAPLEGVLDVINAPALALLGRPLIGNGANGAPGTGANGGDGGILIGN
GGAGGSGAAGMPGGNGGAAGLFGNGGAGGAGGNVASGTAGFGGAGGAGGLLYGAGGAGGAGGRAGGGVGGIGGAGGAGGN
GGLLFGAGGAGGVGGLAADAGDGGAGGDGGLFFGVGGAGGAGGTGTNVTGGAGGAGGNGGLLFGAGGVGGVGGDGVAFLG
TAPGGPGGAGGAGGLFGVGGAGGAGGIGLVGNGGAGGSGGSALLWGDGGAGGAGGVGSTTGGAGGAGGNAGLLVGAGGAG
GAGALGGGATGVGGAGGNGGTAGLLFGAGGAGGFGFGGAGGAGGLGGKAGLIGDGGDGGAGGNGTGAKGGDGGAGGGAIL
VGNGGNGGNAGSGTPNGSAGTGGAGGLLGKNGMNGLP

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mycobacterial PE family. PGRS subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000084 [H]

Pfam domain/function: PF00934 PE [H]

EC number: NA

Molecular weight: Translated: 43090; Mature: 42958

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRRSVAAPRRGHRVLTRCQMSFVVTIPEALAAVATDLAGIGSTIGTANAAAAVPTTTVL
CCCCCCCCCCHHHHHHHHHEEEEEEECHHHHHHHHHHHHHHCCHHCCCCCCHHCCHHHHH
AAAADEVSAAMAALFSGHAQAYQALSAQAALFHEQFVRALTAGAGSYAAAEAASAAPLEG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCHHH
VLDVINAPALALLGRPLIGNGANGAPGTGANGGDGGILIGNGGAGGSGAAGMPGGNGGAA
HHHHHCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCC
GLFGNGGAGGAGGNVASGTAGFGGAGGAGGLLYGAGGAGGAGGRAGGGVGGIGGAGGAGG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCC
NGGLLFGAGGAGGVGGLAADAGDGGAGGDGGLFFGVGGAGGAGGTGTNVTGGAGGAGGNG
CCCEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCC
GLLFGAGGVGGVGGDGVAFLGTAPGGPGGAGGAGGLFGVGGAGGAGGIGLVGNGGAGGSG
CEEEECCCCCCCCCCCEEEEECCCCCCCCCCCCCCCEECCCCCCCCCEEEEECCCCCCCC
GSALLWGDGGAGGAGGVGSTTGGAGGAGGNAGLLVGAGGAGGAGALGGGATGVGGAGGNG
CCEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCC
GTAGLLFGAGGAGGFGFGGAGGAGGLGGKAGLIGDGGDGGAGGNGTGAKGGDGGAGGGAI
CCEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCEE
LVGNGGNGGNAGSGTPNGSAGTGGAGGLLGKNGMNGLP
EECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TRRSVAAPRRGHRVLTRCQMSFVVTIPEALAAVATDLAGIGSTIGTANAAAAVPTTTVL
CCCCCCCCCHHHHHHHHHEEEEEEECHHHHHHHHHHHHHHCCHHCCCCCCHHCCHHHHH
AAAADEVSAAMAALFSGHAQAYQALSAQAALFHEQFVRALTAGAGSYAAAEAASAAPLEG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCHHH
VLDVINAPALALLGRPLIGNGANGAPGTGANGGDGGILIGNGGAGGSGAAGMPGGNGGAA
HHHHHCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCC
GLFGNGGAGGAGGNVASGTAGFGGAGGAGGLLYGAGGAGGAGGRAGGGVGGIGGAGGAGG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCC
NGGLLFGAGGAGGVGGLAADAGDGGAGGDGGLFFGVGGAGGAGGTGTNVTGGAGGAGGNG
CCCEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCC
GLLFGAGGVGGVGGDGVAFLGTAPGGPGGAGGAGGLFGVGGAGGAGGIGLVGNGGAGGSG
CEEEECCCCCCCCCCCEEEEECCCCCCCCCCCCCCCEECCCCCCCCCEEEEECCCCCCCC
GSALLWGDGGAGGAGGVGSTTGGAGGAGGNAGLLVGAGGAGGAGALGGGATGVGGAGGNG
CCEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCC
GTAGLLFGAGGAGGFGFGGAGGAGGLGGKAGLIGDGGDGGAGGNGTGAKGGDGGAGGGAI
CCEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCEE
LVGNGGNGGNAGSGTPNGSAGTGGAGGLLGKNGMNGLP
EECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]