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The map label for this gene is eccE5

Identifier: 148823011

GI number: 148823011

Start: 2043735

End: 2044955

Strand: Direct

Name: eccE5

Synonym: TBFG_11828

Alternate gene names: 148823011

Gene position: 2043735-2044955 (Clockwise)

Preceding gene: 148823010

Following gene: 148823012

Centisome position: 46.19

GC content: 64.7

Gene sequence:

>1221_bases
ATGAAGGCTCAGCGCAGCTTCGGGTTGGCGTTGTCGTGGCCGCGGGTGACCGCGGTGTTTCTGGTGGATGTCCTGATCTT
GGCGGTGGCCAGTCATTGCCCGGATTCCTGGCAGGCCGATCATCATGTGGCGTGGTGGGTCGGCGTCGGCGTGGCGGCCG
TAGTGACGTTACTGTCGGTGGTCAGTTACCACGGCATCACGGTGATTTCGGGTTTGGCGACGTGGGTGCGGGATTGGTCG
GCGGATCCGGGCACGACACTGGGTGCGGGGTGCACTCCGGCAATCGACCACCAGCGCCGTTTTGGGCGTGACACGGTAGG
GGTGCGTGAGTATAACGGCCGGCTGGTCTCGGTGATCGAGGTCACCTGCGGTGAGAGCGGCCCGTCGGGTCGGCATTGGC
ACCGGAAATCGCCGGTACCCATGTTGCCGGTGGTCGCGGTCGCCGATGGTTTGCGCCAGTTCGACATTCACCTCGATGGC
ATCGACATCGTGTCGGTGCTGGTGCGGGGCGGGGTTGATGCTGCTAAAGCTTCGGCCTCGCTGCAGGAGTGGGAGCCGCA
GGGCTGGAAATCCGAAGAACGAGCCGGTGATCGCACTGTCGCCGATCGGCGCCGCACCTGGTTGGTGTTACGGATGAATC
CGCAGCGAAATGTGGCTGCGGTGGCGTGTCGTGACTCGTTGGCGTCGACGCTGGTGGCAGCCACCGAGCGGTTGGTCCAG
GATCTGGATGGGCAAAGTTGTGCGGCCCGGCCGGTGACGGCCGATGAGCTGACCGAGGTCGACAGCGCCGTGTTGGCTGA
CTTGGAACCGACATGGAGTCGCCCCGGTTGGCGTCACCTCAAGCATTTCAATGGTTATGCGACCAGTTTTTGGGTTACGC
CGTCAGACATCACGTCGGAGACCTTGGATGAGCTGTGTCTGCCAGATAGCCCCGAAGTCGGGACGACCGTGGTCACGGTG
CGTCTGACCACTCGGGTCGGGTCGCCCGCGCTATCGGCATGGGTGCGTTATCACAGCGACACGCGCCTGCCCAAGGAGGT
AGCGGCCGGACTCAACCGGCTCACCGGTCGCCAGTTGGCCGCGGTGCGTGCCAGCCTGCCGGCCCCGACGCACCGTCCAC
TCCTGGTCATCCCCAGTCGGAACCTGCGTGACCACGACGAGCTCGTGCTGCCGGTGGGCCAGGAACTCGAGCACGCGACA
AGCTCGTTTGTGGGGCAATGA

Upstream 100 bases:

>100_bases
TGCCGATATGGGTGGCCGCCGGGGGATTGGCCGGGGCACTATTGATAGGCGGTGCGGTGTTCGGTACCGCGACCTTGATG
CGGCGATCACGGAAGCAGCA

Downstream 100 bases:

>100_bases
CACGCCCGCAGGCCGCCGCCGAAGATGCCCGCAACGCCATGGTCGCCGGTCTGCTGGCATCGGGGATCTCCGTCAATGGA
CTGCAGCCCAGCCATAACCC

Product: hypothetical protein

Products: NA

Alternate protein names: ESX conserved component E5; Type VII secretion system protein EccE5; T7SS protein EccE5

Number of amino acids: Translated: 406; Mature: 406

Protein sequence:

>406_residues
MKAQRSFGLALSWPRVTAVFLVDVLILAVASHCPDSWQADHHVAWWVGVGVAAVVTLLSVVSYHGITVISGLATWVRDWS
ADPGTTLGAGCTPAIDHQRRFGRDTVGVREYNGRLVSVIEVTCGESGPSGRHWHRKSPVPMLPVVAVADGLRQFDIHLDG
IDIVSVLVRGGVDAAKASASLQEWEPQGWKSEERAGDRTVADRRRTWLVLRMNPQRNVAAVACRDSLASTLVAATERLVQ
DLDGQSCAARPVTADELTEVDSAVLADLEPTWSRPGWRHLKHFNGYATSFWVTPSDITSETLDELCLPDSPEVGTTVVTV
RLTTRVGSPALSAWVRYHSDTRLPKEVAAGLNRLTGRQLAAVRASLPAPTHRPLLVIPSRNLRDHDELVLPVGQELEHAT
SSFVGQ

Sequences:

>Translated_406_residues
MKAQRSFGLALSWPRVTAVFLVDVLILAVASHCPDSWQADHHVAWWVGVGVAAVVTLLSVVSYHGITVISGLATWVRDWS
ADPGTTLGAGCTPAIDHQRRFGRDTVGVREYNGRLVSVIEVTCGESGPSGRHWHRKSPVPMLPVVAVADGLRQFDIHLDG
IDIVSVLVRGGVDAAKASASLQEWEPQGWKSEERAGDRTVADRRRTWLVLRMNPQRNVAAVACRDSLASTLVAATERLVQ
DLDGQSCAARPVTADELTEVDSAVLADLEPTWSRPGWRHLKHFNGYATSFWVTPSDITSETLDELCLPDSPEVGTTVVTV
RLTTRVGSPALSAWVRYHSDTRLPKEVAAGLNRLTGRQLAAVRASLPAPTHRPLLVIPSRNLRDHDELVLPVGQELEHAT
SSFVGQ
>Mature_406_residues
MKAQRSFGLALSWPRVTAVFLVDVLILAVASHCPDSWQADHHVAWWVGVGVAAVVTLLSVVSYHGITVISGLATWVRDWS
ADPGTTLGAGCTPAIDHQRRFGRDTVGVREYNGRLVSVIEVTCGESGPSGRHWHRKSPVPMLPVVAVADGLRQFDIHLDG
IDIVSVLVRGGVDAAKASASLQEWEPQGWKSEERAGDRTVADRRRTWLVLRMNPQRNVAAVACRDSLASTLVAATERLVQ
DLDGQSCAARPVTADELTEVDSAVLADLEPTWSRPGWRHLKHFNGYATSFWVTPSDITSETLDELCLPDSPEVGTTVVTV
RLTTRVGSPALSAWVRYHSDTRLPKEVAAGLNRLTGRQLAAVRASLPAPTHRPLLVIPSRNLRDHDELVLPVGQELEHAT
SSFVGQ

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EccE family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ECCE5_MYCTU (O53946)

Other databases:

- EMBL:   BX842577
- EMBL:   AE000516
- PIR:   F70930
- RefSeq:   NP_216313.1
- RefSeq:   NP_336303.1
- EnsemblBacteria:   EBMYCT00000002389
- EnsemblBacteria:   EBMYCT00000071601
- GeneID:   885452
- GeneID:   925106
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT1846
- KEGG:   mtu:Rv1797
- TIGR:   MT1846
- TubercuList:   Rv1797
- GeneTree:   EBGT00050000015325
- HOGENOM:   HBG569277
- OMA:   LWDWSAD
- ProtClustDB:   CLSK791400
- GO:   GO:0005829
- InterPro:   IPR021368

Pfam domain/function: PF11203 DUF2984

EC number: NA

Molecular weight: Translated: 44178; Mature: 44178

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1aeff024)-; HASH(0x170915a8)-;

Cys/Met content:

1.5 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAQRSFGLALSWPRVTAVFLVDVLILAVASHCPDSWQADHHVAWWVGVGVAAVVTLLSV
CCCCCCCCCEEECHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEHHHHHHHHHHHHHHHH
VSYHGITVISGLATWVRDWSADPGTTLGAGCTPAIDHQRRFGRDTVGVREYNGRLVSVIE
HHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHCCCCCCCEECCCCEEEEEEE
VTCGESGPSGRHWHRKSPVPMLPVVAVADGLRQFDIHLDGIDIVSVLVRGGVDAAKASAS
EECCCCCCCCCCCCCCCCCCCHHHHHHHCCHHEEEEEECCHHHHHHHHHCCCHHHHHHCH
LQEWEPQGWKSEERAGDRTVADRRRTWLVLRMNPQRNVAAVACRDSLASTLVAATERLVQ
HHHCCCCCCCCHHHCCCCHHHCCCCEEEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHH
DLDGQSCAARPVTADELTEVDSAVLADLEPTWSRPGWRHLKHFNGYATSFWVTPSDITSE
HCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCEEEEEECCHHHHHH
TLDELCLPDSPEVGTTVVTVRLTTRVGSPALSAWVRYHSDTRLPKEVAAGLNRLTGRQLA
HHHHHCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHH
AVRASLPAPTHRPLLVIPSRNLRDHDELVLPVGQELEHATSSFVGQ
HHHHHCCCCCCCCEEEECCCCCCCCCCEEECCCHHHHHHHHHHCCH
>Mature Secondary Structure
MKAQRSFGLALSWPRVTAVFLVDVLILAVASHCPDSWQADHHVAWWVGVGVAAVVTLLSV
CCCCCCCCCEEECHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEHHHHHHHHHHHHHHHH
VSYHGITVISGLATWVRDWSADPGTTLGAGCTPAIDHQRRFGRDTVGVREYNGRLVSVIE
HHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHCCCCCCCEECCCCEEEEEEE
VTCGESGPSGRHWHRKSPVPMLPVVAVADGLRQFDIHLDGIDIVSVLVRGGVDAAKASAS
EECCCCCCCCCCCCCCCCCCCHHHHHHHCCHHEEEEEECCHHHHHHHHHCCCHHHHHHCH
LQEWEPQGWKSEERAGDRTVADRRRTWLVLRMNPQRNVAAVACRDSLASTLVAATERLVQ
HHHCCCCCCCCHHHCCCCHHHCCCCEEEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHH
DLDGQSCAARPVTADELTEVDSAVLADLEPTWSRPGWRHLKHFNGYATSFWVTPSDITSE
HCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCEEEEEECCHHHHHH
TLDELCLPDSPEVGTTVVTVRLTTRVGSPALSAWVRYHSDTRLPKEVAAGLNRLTGRQLA
HHHHHCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHH
AVRASLPAPTHRPLLVIPSRNLRDHDELVLPVGQELEHATSSFVGQ
HHHHHCCCCCCCCEEEECCCCCCCCCCEEECCCHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036