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The map label for this gene is ppe21 [H]

Identifier: 148822772

GI number: 148822772

Start: 1755934

End: 1758216

Strand: Reverse

Name: ppe21 [H]

Synonym: TBFG_11581

Alternate gene names: 148822772

Gene position: 1758216-1755934 (Counterclockwise)

Preceding gene: 148822785

Following gene: 148822766

Centisome position: 39.74

GC content: 62.64

Gene sequence:

>2283_bases
ATGGCCCAGGTCACATCGGTGAGCGTACGTCCACAATCGAAGGACGCGGAAGCACGGGGGCCGCGACCACCGAGACCCGT
GGCGGCCCATGGCCGCAAGGAGGCTCCTCGCGAGATTCGTCACGCGTTACCTGGATTTAACCTGCGCCCGTCCGAAGCGC
CCGGCTTTTTCGTAGGCTTCGCTGCGGTTGGGGCCAGACAGCGCCGTGAAGCCCGGTGGGTGTGGCCGGCTGACGGGATG
GTTGTGATGAATTTTTCGGTGTTGCCGCCGGAGATCAATTCGGCGCTGATGTTCGCTGGTGCCGGGCCGGGACCGATGTT
GGCGGCGGCGTCGGCCTGGACCGGGCTGGCCGGCGATTTGGGTTCGGCGGCGGCCTCATTTTCGGCGGTGACCTCGCAGT
TGGCCACCGGGTCCTGGCAAGGTCCGGCGTCAGCGGCCATGACAGGCGTGGCCGCGTCCTATGCTCGCTGGCTGACCACG
GCCGCAGCGCAGGCTGAGCAGGCGGCGGGTCAAGCCCAGGCGGCGGTATCGGCGTTCGAGGCGGCGCTGGCGGCGACGGT
GCATCCGGGCGCGGTGAGCGCCAATCGAGGTCGGTTGCGCTCCTTGGTGGCCTCGAATCTGTTGGGGCAAAACGCCCCGG
CCATCGCGGCCGTCGAGGCCGTCTATGAGCAGATGTGGGCCGCCGATGTCGCCGCGATGCTCGGTTATCACGGCGAGGCG
TCGGCGGTCGCCTTGTCGCTGACGCCGTTCACACCGTCGCCGAGCGCGGCAGCCACGCCCGGCGGTGCGGTGATCATCGC
GGGGTTTCCGTTTCTCGATCTGGGCAACGTCACCATCGGTGGCTTCAATCTGGCCAGCGGCAATCTGGGCCTCGGCAACC
TGGGCAGCTTCAACCCGGGTAGCGCCAACACGGGCAGCGTCAACTTGGGCAACGCCAATATCGGTGATCTCAACCTGGGC
AGCGGCAATATCGGCAGCTACAACCTGGGTGGCGGCAACACCGGGGATCTCAACCCGGGCAGTGGAAACACGGGCACGCT
CAACTGGGGTAGCGGAAACATCGGCAGCTATAACCTGGGCGGCGGCAACCTCGGCAGCTATAACCTGGGTAGTGGAAATA
CCGGCGACACCAACTTTGGCGGCGGTAACACCGGAAATCTCAACGTGGGTGGCGGCAACACCGGGAACTCGAATTTCGGG
TTCGGAAACACCGGTAACGTCAACTTTGGTAACGGAAACACCGGCGACACCAACTTTGGCAGCGGCAACCTTGGCAGTGG
AAATATCGGTTTCGGCAACAAGGGCTCTCATAACATCGGGTTTGGGAACAGCGGCAACAACAACATCGGCTTCGGGCTCA
CCGGTGATAACCAGATAGGTTTCGGCGCCCTCAATTCAGGTAGCGGGAACCTCGGCTTCGGGAACTCGGGCAACGGTAAT
ATCGGCTTTTTCAACTCGGGCAATAACAACATCGGCATGGGAAACTCGGGCAATGGAGTCGGGGCGCTGAGCGTGGAGTT
CGGCAGTTCGGCCGAGCGCAGCTCGGGCTTCGGCAACTCCGGCGAGCTCAGTACCGGTATCGGCAACTCCGGCCAGCTCA
GCACGGGCTGGTTCAACTCGGCCACCACCAGCACCGGCTGGTTCAACTCCGGCACCACCAATACCGGCTGGTTCAACTCG
GGCACCACGAACACCGGAATCGGAAACTCGGGCGGAAACCTGGTCACCGGCAGCATGGGTCTGTTTAACTCCGGCCATAC
CAACACGGGTAGCTTCAATGCCGGCAGCATGAACACGGGCGATTTCAACTCGGGCAACGTGAACACCGGCTACTTCAACT
CCGGCAACATCAACACCGGCTTCTTCAACTCGGGCGATCTCAACACCGGATTGTTCAACTCGGTCAACCAGCCGGTACAG
AACTCCGGCTGGCTGCACACGGGCACCAACAACTCGGGCTACGCTAACGCCGGCACCTTCAACTCGGGCTTCGATAACAA
CGCCCGTGACGAACACGCCGAATTTGTCACCGGTAACTCGGGCCTGGCCAACGTGGGCAACTACAACGCCGGCATCATCA
ACGTGGGTGACCATCTGTCGGGCTTCAGAAACTCGGTACCCACGATCACCGGTACGGCCAACATTTCGGGTTTCGTCAAT
GCGGGAACCTCGATCTCTGGCTTCTTCAACTTCGGCAGCCTCATGTCGGGCTTCGCCAACTTCGACGACGAGGTCTCGGG
GTATCTCAACGGGGACAGTCGGGCGTCGGGCTGGATCCATTAG

Upstream 100 bases:

>100_bases
CGGCGTCCGGGTCCATGACGGCGGTGCGCTGGAACGCCTCGCACATGGTTGTCGGGCGCTCTGTTGTGGTCATTTCCGTT
CTCCTTGACAGCGGATCAGT

Downstream 100 bases:

>100_bases
CGGCGCTCACGGGCGATCGTGCGGAAACCGCTGGGGGCGGTCGCCTCGCTAACTCCCCAGACATCCAGGGCCGAGCAGCT
CCTTGAGGTCACCCATCAAC

Product: PPE family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 760; Mature: 759

Protein sequence:

>760_residues
MAQVTSVSVRPQSKDAEARGPRPPRPVAAHGRKEAPREIRHALPGFNLRPSEAPGFFVGFAAVGARQRREARWVWPADGM
VVMNFSVLPPEINSALMFAGAGPGPMLAAASAWTGLAGDLGSAAASFSAVTSQLATGSWQGPASAAMTGVAASYARWLTT
AAAQAEQAAGQAQAAVSAFEAALAATVHPGAVSANRGRLRSLVASNLLGQNAPAIAAVEAVYEQMWAADVAAMLGYHGEA
SAVALSLTPFTPSPSAAATPGGAVIIAGFPFLDLGNVTIGGFNLASGNLGLGNLGSFNPGSANTGSVNLGNANIGDLNLG
SGNIGSYNLGGGNTGDLNPGSGNTGTLNWGSGNIGSYNLGGGNLGSYNLGSGNTGDTNFGGGNTGNLNVGGGNTGNSNFG
FGNTGNVNFGNGNTGDTNFGSGNLGSGNIGFGNKGSHNIGFGNSGNNNIGFGLTGDNQIGFGALNSGSGNLGFGNSGNGN
IGFFNSGNNNIGMGNSGNGVGALSVEFGSSAERSSGFGNSGELSTGIGNSGQLSTGWFNSATTSTGWFNSGTTNTGWFNS
GTTNTGIGNSGGNLVTGSMGLFNSGHTNTGSFNAGSMNTGDFNSGNVNTGYFNSGNINTGFFNSGDLNTGLFNSVNQPVQ
NSGWLHTGTNNSGYANAGTFNSGFDNNARDEHAEFVTGNSGLANVGNYNAGIINVGDHLSGFRNSVPTITGTANISGFVN
AGTSISGFFNFGSLMSGFANFDDEVSGYLNGDSRASGWIH

Sequences:

>Translated_760_residues
MAQVTSVSVRPQSKDAEARGPRPPRPVAAHGRKEAPREIRHALPGFNLRPSEAPGFFVGFAAVGARQRREARWVWPADGM
VVMNFSVLPPEINSALMFAGAGPGPMLAAASAWTGLAGDLGSAAASFSAVTSQLATGSWQGPASAAMTGVAASYARWLTT
AAAQAEQAAGQAQAAVSAFEAALAATVHPGAVSANRGRLRSLVASNLLGQNAPAIAAVEAVYEQMWAADVAAMLGYHGEA
SAVALSLTPFTPSPSAAATPGGAVIIAGFPFLDLGNVTIGGFNLASGNLGLGNLGSFNPGSANTGSVNLGNANIGDLNLG
SGNIGSYNLGGGNTGDLNPGSGNTGTLNWGSGNIGSYNLGGGNLGSYNLGSGNTGDTNFGGGNTGNLNVGGGNTGNSNFG
FGNTGNVNFGNGNTGDTNFGSGNLGSGNIGFGNKGSHNIGFGNSGNNNIGFGLTGDNQIGFGALNSGSGNLGFGNSGNGN
IGFFNSGNNNIGMGNSGNGVGALSVEFGSSAERSSGFGNSGELSTGIGNSGQLSTGWFNSATTSTGWFNSGTTNTGWFNS
GTTNTGIGNSGGNLVTGSMGLFNSGHTNTGSFNAGSMNTGDFNSGNVNTGYFNSGNINTGFFNSGDLNTGLFNSVNQPVQ
NSGWLHTGTNNSGYANAGTFNSGFDNNARDEHAEFVTGNSGLANVGNYNAGIINVGDHLSGFRNSVPTITGTANISGFVN
AGTSISGFFNFGSLMSGFANFDDEVSGYLNGDSRASGWIH
>Mature_759_residues
AQVTSVSVRPQSKDAEARGPRPPRPVAAHGRKEAPREIRHALPGFNLRPSEAPGFFVGFAAVGARQRREARWVWPADGMV
VMNFSVLPPEINSALMFAGAGPGPMLAAASAWTGLAGDLGSAAASFSAVTSQLATGSWQGPASAAMTGVAASYARWLTTA
AAQAEQAAGQAQAAVSAFEAALAATVHPGAVSANRGRLRSLVASNLLGQNAPAIAAVEAVYEQMWAADVAAMLGYHGEAS
AVALSLTPFTPSPSAAATPGGAVIIAGFPFLDLGNVTIGGFNLASGNLGLGNLGSFNPGSANTGSVNLGNANIGDLNLGS
GNIGSYNLGGGNTGDLNPGSGNTGTLNWGSGNIGSYNLGGGNLGSYNLGSGNTGDTNFGGGNTGNLNVGGGNTGNSNFGF
GNTGNVNFGNGNTGDTNFGSGNLGSGNIGFGNKGSHNIGFGNSGNNNIGFGLTGDNQIGFGALNSGSGNLGFGNSGNGNI
GFFNSGNNNIGMGNSGNGVGALSVEFGSSAERSSGFGNSGELSTGIGNSGQLSTGWFNSATTSTGWFNSGTTNTGWFNSG
TTNTGIGNSGGNLVTGSMGLFNSGHTNTGSFNAGSMNTGDFNSGNVNTGYFNSGNINTGFFNSGDLNTGLFNSVNQPVQN
SGWLHTGTNNSGYANAGTFNSGFDNNARDEHAEFVTGNSGLANVGNYNAGIINVGDHLSGFRNSVPTITGTANISGFVNA
GTSISGFFNFGSLMSGFANFDDEVSGYLNGDSRASGWIH

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mycobacterial PPE family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002989
- InterPro:   IPR000030 [H]

Pfam domain/function: PF01469 Pentapeptide_2; PF00823 PPE [H]

EC number: NA

Molecular weight: Translated: 75657; Mature: 75526

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQVTSVSVRPQSKDAEARGPRPPRPVAAHGRKEAPREIRHALPGFNLRPSEAPGFFVGF
CCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCEEEEH
AAVGARQRREARWVWPADGMVVMNFSVLPPEINSALMFAGAGPGPMLAAASAWTGLAGDL
HHHCHHHHCCCCEECCCCCEEEEEEEECCCCCCCEEEEECCCCCCHHHHHHHHCCCCCCH
GSAAASFSAVTSQLATGSWQGPASAAMTGVAASYARWLTTAAAQAEQAAGQAQAAVSAFE
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AALAATVHPGAVSANRGRLRSLVASNLLGQNAPAIAAVEAVYEQMWAADVAAMLGYHGEA
HHHHHEECCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
SAVALSLTPFTPSPSAAATPGGAVIIAGFPFLDLGNVTIGGFNLASGNLGLGNLGSFNPG
CEEEEEEECCCCCCCCCCCCCCEEEEECCCCEEECCEEECCEEECCCCCCCCCCCCCCCC
SANTGSVNLGNANIGDLNLGSGNIGSYNLGGGNTGDLNPGSGNTGTLNWGSGNIGSYNLG
CCCCCEEECCCCCCCCEECCCCCCCEEECCCCCCCCCCCCCCCCEEEECCCCCCCEEECC
GGNLGSYNLGSGNTGDTNFGGGNTGNLNVGGGNTGNSNFGFGNTGNVNFGNGNTGDTNFG
CCCCCCEECCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCEECCCCCCCCCCCC
SGNLGSGNIGFGNKGSHNIGFGNSGNNNIGFGLTGDNQIGFGALNSGSGNLGFGNSGNGN
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCEEEECCCCCCCCCCCCCCCC
IGFFNSGNNNIGMGNSGNGVGALSVEFGSSAERSSGFGNSGELSTGIGNSGQLSTGWFNS
EEEEECCCCCCCCCCCCCCEEEEEEECCCCCHHHCCCCCCCCEECCCCCCCCCCCCCCCC
ATTSTGWFNSGTTNTGWFNSGTTNTGIGNSGGNLVTGSMGLFNSGHTNTGSFNAGSMNTG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCC
DFNSGNVNTGYFNSGNINTGFFNSGDLNTGLFNSVNQPVQNSGWLHTGTNNSGYANAGTF
CCCCCCCCCCEECCCCCCCCEECCCCCCCHHHHHCCCCHHCCCCEEECCCCCCCCCCCCC
NSGFDNNARDEHAEFVTGNSGLANVGNYNAGIINVGDHLSGFRNSVPTITGTANISGFVN
CCCCCCCCCCCCCEEEECCCCCCCCCCCCCCEEECCHHHHHHHHCCCEEEECCCCCEEEE
AGTSISGFFNFGSLMSGFANFDDEVSGYLNGDSRASGWIH
CCCCEEHHHHHHHHHHHHHCCCCHHCEEECCCCCCCCCCC
>Mature Secondary Structure 
AQVTSVSVRPQSKDAEARGPRPPRPVAAHGRKEAPREIRHALPGFNLRPSEAPGFFVGF
CCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCEEEEH
AAVGARQRREARWVWPADGMVVMNFSVLPPEINSALMFAGAGPGPMLAAASAWTGLAGDL
HHHCHHHHCCCCEECCCCCEEEEEEEECCCCCCCEEEEECCCCCCHHHHHHHHCCCCCCH
GSAAASFSAVTSQLATGSWQGPASAAMTGVAASYARWLTTAAAQAEQAAGQAQAAVSAFE
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AALAATVHPGAVSANRGRLRSLVASNLLGQNAPAIAAVEAVYEQMWAADVAAMLGYHGEA
HHHHHEECCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
SAVALSLTPFTPSPSAAATPGGAVIIAGFPFLDLGNVTIGGFNLASGNLGLGNLGSFNPG
CEEEEEEECCCCCCCCCCCCCCEEEEECCCCEEECCEEECCEEECCCCCCCCCCCCCCCC
SANTGSVNLGNANIGDLNLGSGNIGSYNLGGGNTGDLNPGSGNTGTLNWGSGNIGSYNLG
CCCCCEEECCCCCCCCEECCCCCCCEEECCCCCCCCCCCCCCCCEEEECCCCCCCEEECC
GGNLGSYNLGSGNTGDTNFGGGNTGNLNVGGGNTGNSNFGFGNTGNVNFGNGNTGDTNFG
CCCCCCEECCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCEECCCCCCCCCCCC
SGNLGSGNIGFGNKGSHNIGFGNSGNNNIGFGLTGDNQIGFGALNSGSGNLGFGNSGNGN
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCEEEECCCCCCCCCCCCCCCC
IGFFNSGNNNIGMGNSGNGVGALSVEFGSSAERSSGFGNSGELSTGIGNSGQLSTGWFNS
EEEEECCCCCCCCCCCCCCEEEEEEECCCCCHHHCCCCCCCCEECCCCCCCCCCCCCCCC
ATTSTGWFNSGTTNTGWFNSGTTNTGIGNSGGNLVTGSMGLFNSGHTNTGSFNAGSMNTG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCC
DFNSGNVNTGYFNSGNINTGFFNSGDLNTGLFNSVNQPVQNSGWLHTGTNNSGYANAGTF
CCCCCCCCCCEECCCCCCCCEECCCCCCCHHHHHCCCCHHCCCCEEECCCCCCCCCCCCC
NSGFDNNARDEHAEFVTGNSGLANVGNYNAGIINVGDHLSGFRNSVPTITGTANISGFVN
CCCCCCCCCCCCCEEEECCCCCCCCCCCCCCEEECCHHHHHHHHCCCEEEECCCCCEEEE
AGTSISGFFNFGSLMSGFANFDDEVSGYLNGDSRASGWIH
CCCCEEHHHHHHHHHHHHHCCCCHHCEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]