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The map label for this gene is lspA [H]

Identifier: 148822762

GI number: 148822762

Start: 1746815

End: 1747489

Strand: Direct

Name: lspA [H]

Synonym: TBFG_11572

Alternate gene names: 148822762

Gene position: 1746815-1747489 (Clockwise)

Preceding gene: 148822761

Following gene: 148822764

Centisome position: 39.48

GC content: 64.74

Gene sequence:

>675_bases
GTGGTTTGCTCCCATCCGGCCGCGGGGTCTGGGCGGGCCATATCGGCCCTAGGGGATGATGATGGTGTGCCTGACGAACC
AACAGGATCGGCTGATCCGCTGACCTCGACCGAGGAAGCCGGGGGGGCGGGGGAACCTAACGCTCCCGCGCCGCCGCGAC
GGCTGCGCATGCTGCTGTCGGTCGCTGTGGTGGTGCTCACACTCGACATTGTCACCAAGGTGGTAGCTGTCCAACTGTTG
CCGCCCGGCCAGCCGGTGTCGATTATCGGCGACACGGTGACCTGGACTCTGGTGCGTAATTCTGGGGCGGCCTTCTCGAT
GGCGACCGGATACACCTGGGTTTTGACGCTGATTGCGACGGGTGTCGTGGTCGGAATTTTCTGGATGGGGCGGCGGCTGG
TATCGCCGTGGTGGGCGCTGGGTCTTGGGATGATCCTGGGCGGTGCCATGGGCAACCTGGTTGATCGCTTCTTTCGGGCA
CCGGGGCCGCTGCGCGGGCACGTCGTCGATTTCTTGTCGGTCGGCTGGTGGCCGGTGTTCAATGTCGCCGATCCGTCGGT
AGTCGGTGGCGCCATCCTGCTGGTCATCCTGTCGATCTTTGGCTTTGACTTCGACACCGTAGGTCGGCGACACGCCGACG
GGGACACCGTAGGTCGGCGCAAAGCCGATGGCTGA

Upstream 100 bases:

>100_bases
AATGGGTTGGCCGTAGCACCCCATCGGGGCCGGCGGTGGTCGAGATTGTCCCTCCAGTAGTGATGACGGTGAGGCGGGCC
ATGATGGGATCATTGCGCAC

Downstream 100 bases:

>100_bases
CCGCTCAATGCCCGTTCCGGATGGATTGGCGGGAATGCGTGTTGACACCGGACTGGCCCGCTTGCTGGGACTGTCTCGGA
CCGCTGCGGCTGCCCTCGCC

Product: lipoprotein signal peptidase

Products: NA

Alternate protein names: Prolipoprotein signal peptidase; Signal peptidase II; SPase II [H]

Number of amino acids: Translated: 224; Mature: 224

Protein sequence:

>224_residues
MVCSHPAAGSGRAISALGDDDGVPDEPTGSADPLTSTEEAGGAGEPNAPAPPRRLRMLLSVAVVVLTLDIVTKVVAVQLL
PPGQPVSIIGDTVTWTLVRNSGAAFSMATGYTWVLTLIATGVVVGIFWMGRRLVSPWWALGLGMILGGAMGNLVDRFFRA
PGPLRGHVVDFLSVGWWPVFNVADPSVVGGAILLVILSIFGFDFDTVGRRHADGDTVGRRKADG

Sequences:

>Translated_224_residues
MVCSHPAAGSGRAISALGDDDGVPDEPTGSADPLTSTEEAGGAGEPNAPAPPRRLRMLLSVAVVVLTLDIVTKVVAVQLL
PPGQPVSIIGDTVTWTLVRNSGAAFSMATGYTWVLTLIATGVVVGIFWMGRRLVSPWWALGLGMILGGAMGNLVDRFFRA
PGPLRGHVVDFLSVGWWPVFNVADPSVVGGAILLVILSIFGFDFDTVGRRHADGDTVGRRKADG
>Mature_224_residues
MVCSHPAAGSGRAISALGDDDGVPDEPTGSADPLTSTEEAGGAGEPNAPAPPRRLRMLLSVAVVVLTLDIVTKVVAVQLL
PPGQPVSIIGDTVTWTLVRNSGAAFSMATGYTWVLTLIATGVVVGIFWMGRRLVSPWWALGLGMILGGAMGNLVDRFFRA
PGPLRGHVVDFLSVGWWPVFNVADPSVVGGAILLVILSIFGFDFDTVGRRHADGDTVGRRKADG

Specific function: This protein specifically catalyzes the removal of signal peptides from prolipoproteins [H]

COG id: COG0597

COG function: function code MU; Lipoprotein signal peptidase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A8 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001872 [H]

Pfam domain/function: PF01252 Peptidase_A8 [H]

EC number: =3.4.23.36 [H]

Molecular weight: Translated: 23382; Mature: 23382

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: PS00855 SPASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVCSHPAAGSGRAISALGDDDGVPDEPTGSADPLTSTEEAGGAGEPNAPAPPRRLRMLLS
CCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
VAVVVLTLDIVTKVVAVQLLPPGQPVSIIGDTVTWTLVRNSGAAFSMATGYTWVLTLIAT
HHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCEEEEEEECCCCEEEHHHHHHHHHHHHHH
GVVVGIFWMGRRLVSPWWALGLGMILGGAMGNLVDRFFRAPGPLRGHVVDFLSVGWWPVF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCEEEE
NVADPSVVGGAILLVILSIFGFDFDTVGRRHADGDTVGRRKADG
CCCCCHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MVCSHPAAGSGRAISALGDDDGVPDEPTGSADPLTSTEEAGGAGEPNAPAPPRRLRMLLS
CCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
VAVVVLTLDIVTKVVAVQLLPPGQPVSIIGDTVTWTLVRNSGAAFSMATGYTWVLTLIAT
HHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCEEEEEEECCCCEEEHHHHHHHHHHHHHH
GVVVGIFWMGRRLVSPWWALGLGMILGGAMGNLVDRFFRAPGPLRGHVVDFLSVGWWPVF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCEEEE
NVADPSVVGGAILLVILSIFGFDFDTVGRRHADGDTVGRRKADG
CCCCCHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]