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The map label for this gene is 148822734

Identifier: 148822734

GI number: 148822734

Start: 1705932

End: 1707230

Strand: Direct

Name: 148822734

Synonym: TBFG_11543

Alternate gene names: NA

Gene position: 1705932-1707230 (Clockwise)

Preceding gene: 148822733

Following gene: 148822735

Centisome position: 38.56

GC content: 68.59

Gene sequence:

>1299_bases
ATGTACGAGAGACGGCATGAGCGCGGAATGTGCGACCGTGCCGTCGAGATGACCGACGTCGGCGCTACGGCAGCCCCCAC
CGGACCTATCGCGCGGGGCAGCGTCGCTCGGGTCGGCGCGGCGACCGCGTTGGCCGTTGCCTGCGTCTACACGGTCATCT
ATCTGGCGGCCCGCGACCTACCCCCGGCTTGTTTTTCGATATTCGCGGTGTTTTGGGGGGCGCTCGGCATTGCCACCGGC
GCCACCCACGGCCTCCTGCAAGAAACGACCCGCGAGGTCCGCTGGGTGCGCTCCACCCAAATAGTTGCGGGCCATCGTAC
CCATCCGCTGCGGGTGGCCGGGATGATTGGCACCGTCGCGGCCGTCGTAATTGCGGGTAGCTCACCGCTGTGGAGCCGAC
AGCTATTCGTCGAGGGGCGCTGGCTGTCCGTGGGGCTACTCAGCGTTGGGGTGGCCGGGTTCTGCGCGCAGGCGACCCTG
CTGGGCGCGCTGGCCGGCGTCGACCGGTGGACACAGTACGGGTCACTGATGGTGACCGACGCGGTCATCCGGTTGGCGGT
CGCCGCGGCAGCGGTTGTGATCGGATGGGGTCTGGCCGGGTACTTGTGGGCCGCCACCGCGGGAGCGGTGGCGTGGCTGC
TCATGCTGATGGCCTCGCCCACCGCGCGCAGCGCGGCCAGCCTGCTGACGCCCGGGGGAATCGCCACGTTCGTGCGCGGT
GCCGCTCATTCGATAACCGCCGCGGGTGCCAGCGCGATTCTGGTAATGGGTTTCCCAGTGTTGCTCAAAGTGACCTCCGA
CCAGTTAGGGGCAAAGGGCGGAGCGGTCATCCTGGCTGTGACCTTGACGCGTGCGCCGCTTCTGGTCCCACTGAGCGCGA
TGCAAGGCAACCTGATCGCGCATTTCGTCGACCGGCGCACCCAACGGCTTCGGGCGCTGATCGCACCGGCGCTGGTCGTC
GGCGGCATCGGTGCGGTCGGGATGTTGGCCGCAGGGCTTACCGGTCCCTGGTTGCTGCGTGTTGGATTCGGCCCCGACTA
CCAAACTGGCGGGGCGTTGCTGGCCTGGTTGACGGCAGCGGCGGTAGCTATCGCCATGCTGACGCTGACCGGCGCCGCCG
CGGTCGCGGCCGCACTGCACCGGGCGTATTTGCTGGGCTGGGTCAGCGCGACGGTGGCGTCGACGCTGTTGCTGCTGCTG
CCGATGCCGCTGGAGACGCGCACCGTGATCGCGCTGTTGTTCGGTCCAACGGTGGGAATCGCCATCCATGTGGCCGCGTT
GGCGCGGCGACCCGACTGA

Upstream 100 bases:

>100_bases
GGATCACAACCGACCCCATCCAGTCGTTGCCAGGCATGCGTACTCTCGACCTCGGTTGCTGGCCAGCGGTGATACACAGC
TCCCCGCCAGTGGACGTGAC

Downstream 100 bases:

>100_bases
TTTGTGCCCCAGGTCGACAAATCACGCCGTCTCGTCAGTGAGCACTCCGTCCTCGGGTCCGATCCTTCCAGGAGACGTTG
CAACCTGATTTGGCTCAAAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 432; Mature: 432

Protein sequence:

>432_residues
MYERRHERGMCDRAVEMTDVGATAAPTGPIARGSVARVGAATALAVACVYTVIYLAARDLPPACFSIFAVFWGALGIATG
ATHGLLQETTREVRWVRSTQIVAGHRTHPLRVAGMIGTVAAVVIAGSSPLWSRQLFVEGRWLSVGLLSVGVAGFCAQATL
LGALAGVDRWTQYGSLMVTDAVIRLAVAAAAVVIGWGLAGYLWAATAGAVAWLLMLMASPTARSAASLLTPGGIATFVRG
AAHSITAAGASAILVMGFPVLLKVTSDQLGAKGGAVILAVTLTRAPLLVPLSAMQGNLIAHFVDRRTQRLRALIAPALVV
GGIGAVGMLAAGLTGPWLLRVGFGPDYQTGGALLAWLTAAAVAIAMLTLTGAAAVAAALHRAYLLGWVSATVASTLLLLL
PMPLETRTVIALLFGPTVGIAIHVAALARRPD

Sequences:

>Translated_432_residues
MYERRHERGMCDRAVEMTDVGATAAPTGPIARGSVARVGAATALAVACVYTVIYLAARDLPPACFSIFAVFWGALGIATG
ATHGLLQETTREVRWVRSTQIVAGHRTHPLRVAGMIGTVAAVVIAGSSPLWSRQLFVEGRWLSVGLLSVGVAGFCAQATL
LGALAGVDRWTQYGSLMVTDAVIRLAVAAAAVVIGWGLAGYLWAATAGAVAWLLMLMASPTARSAASLLTPGGIATFVRG
AAHSITAAGASAILVMGFPVLLKVTSDQLGAKGGAVILAVTLTRAPLLVPLSAMQGNLIAHFVDRRTQRLRALIAPALVV
GGIGAVGMLAAGLTGPWLLRVGFGPDYQTGGALLAWLTAAAVAIAMLTLTGAAAVAAALHRAYLLGWVSATVASTLLLLL
PMPLETRTVIALLFGPTVGIAIHVAALARRPD
>Mature_432_residues
MYERRHERGMCDRAVEMTDVGATAAPTGPIARGSVARVGAATALAVACVYTVIYLAARDLPPACFSIFAVFWGALGIATG
ATHGLLQETTREVRWVRSTQIVAGHRTHPLRVAGMIGTVAAVVIAGSSPLWSRQLFVEGRWLSVGLLSVGVAGFCAQATL
LGALAGVDRWTQYGSLMVTDAVIRLAVAAAAVVIGWGLAGYLWAATAGAVAWLLMLMASPTARSAASLLTPGGIATFVRG
AAHSITAAGASAILVMGFPVLLKVTSDQLGAKGGAVILAVTLTRAPLLVPLSAMQGNLIAHFVDRRTQRLRALIAPALVV
GGIGAVGMLAAGLTGPWLLRVGFGPDYQTGGALLAWLTAAAVAIAMLTLTGAAAVAAALHRAYLLGWVSATVASTLLLLL
PMPLETRTVIALLFGPTVGIAIHVAALARRPD

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To M.tuberculosis Rv3630 and M.bovis Mb3654

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y1510_MYCTU (P71789)

Other databases:

- EMBL:   BX842576
- EMBL:   AE000516
- EMBL:   AE000516
- PIR:   A70714
- RefSeq:   NP_216026.1
- RefSeq:   NP_336011.1
- RefSeq:   NP_336012.1
- ProteinModelPortal:   P71789
- EnsemblBacteria:   EBMYCT00000003026
- EnsemblBacteria:   EBMYCT00000071026
- GeneID:   886466
- GeneID:   924401
- GeneID:   924403
- GenomeReviews:   AL123456_GR
- KEGG:   mtu:Rv1510
- TIGR:   MT1558
- TIGR:   MT1560
- TubercuList:   Rv1510
- GeneTree:   EBGT00050000015677
- HOGENOM:   HBG565044
- OMA:   TQETTRA
- ProtClustDB:   CLSK871943

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 44294; Mature: 44294

Theoretical pI: Translated: 11.15; Mature: 11.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x197db598)-; HASH(0x18351e98)-; HASH(0x1a56dcc4)-; HASH(0x1a52c188)-; HASH(0x1713fa1c)-; HASH(0x180e046c)-; HASH(0x1a892eec)-; HASH(0x1a751644)-; HASH(0x1a68e010)-; HASH(0x1a704b8c)-; HASH(0x19a540bc)-; HASH(0x19e4b9f0)-;

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYERRHERGMCDRAVEMTDVGATAAPTGPIARGSVARVGAATALAVACVYTVIYLAARDL
CCCCCHHCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
PPACFSIFAVFWGALGIATGATHGLLQETTREVRWVRSTQIVAGHRTHPLRVAGMIGTVA
CHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHH
AVVIAGSSPLWSRQLFVEGRWLSVGLLSVGVAGFCAQATLLGALAGVDRWTQYGSLMVTD
HHHEECCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
AVIRLAVAAAAVVIGWGLAGYLWAATAGAVAWLLMLMASPTARSAASLLTPGGIATFVRG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHH
AAHSITAAGASAILVMGFPVLLKVTSDQLGAKGGAVILAVTLTRAPLLVPLSAMQGNLIA
HHHHHHHCCHHHHHHHCCHHHEEECCHHCCCCCCEEEEEEEECCCCCEEEHHHHCCHHHH
HFVDRRTQRLRALIAPALVVGGIGAVGMLAAGLTGPWLLRVGFGPDYQTGGALLAWLTAA
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHH
AVAIAMLTLTGAAAVAAALHRAYLLGWVSATVASTLLLLLPMPLETRTVIALLFGPTVGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHH
AIHVAALARRPD
HHHHHHHHCCCH
>Mature Secondary Structure
MYERRHERGMCDRAVEMTDVGATAAPTGPIARGSVARVGAATALAVACVYTVIYLAARDL
CCCCCHHCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
PPACFSIFAVFWGALGIATGATHGLLQETTREVRWVRSTQIVAGHRTHPLRVAGMIGTVA
CHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHH
AVVIAGSSPLWSRQLFVEGRWLSVGLLSVGVAGFCAQATLLGALAGVDRWTQYGSLMVTD
HHHEECCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
AVIRLAVAAAAVVIGWGLAGYLWAATAGAVAWLLMLMASPTARSAASLLTPGGIATFVRG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHH
AAHSITAAGASAILVMGFPVLLKVTSDQLGAKGGAVILAVTLTRAPLLVPLSAMQGNLIA
HHHHHHHCCHHHHHHHCCHHHEEECCHHCCCCCCEEEEEEEECCCCCEEEHHHHCCHHHH
HFVDRRTQRLRALIAPALVVGGIGAVGMLAAGLTGPWLLRVGFGPDYQTGGALLAWLTAA
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHH
AVAIAMLTLTGAAAVAAALHRAYLLGWVSATVASTLLLLLPMPLETRTVIALLFGPTVGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHH
AIHVAALARRPD
HHHHHHHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036