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The map label for this gene is ppe19

Identifier: 148822583

GI number: 148822583

Start: 1538142

End: 1539332

Strand: Reverse

Name: ppe19

Synonym: TBFG_11392

Alternate gene names: 148822583

Gene position: 1539332-1538142 (Counterclockwise)

Preceding gene: 148822584

Following gene: 148822578

Centisome position: 34.79

GC content: 67.84

Gene sequence:

>1191_bases
GTGGTGGACTTCGGGGCGTTACCACCGGAGATCAACTCCGCGAGGATGTATGCCGGCCCGGGTTCGGCCTCGCTGGTGGC
CGCCGCGAAGATGTGGGACAGCGTGGCGAGTGACCTGTTTTCGGCCGCGTCGGCGTTTCAGTCGGTGGTCTGGGGTCTGA
CGACGGGATCGTGGATAGGTTCGTCGGCGGGTCTGATGGTGGCGGCGGCCTCGCCGTATGTGGCGTGGATGAGCGTCACC
GCGGGGCAGGCCGAGCTGACCGCCGCCCAGGTCCGGGTTGCTGCGGCGGCCTACGAGACGGCGTATGGGCTGACGGTGCC
CCCGCCGGTGATCGCCGAGAACCGTGCTGAACTGATGATTCTGATAGCGACCAACCTCTTGGGGCAAAACACGCCGGCGA
TCGCGGTCAACGAGGCCGAATACGGGGAGATGTGGGCCCAAGACGCCGCCGCGATGTTTGGCTACGCCGCCACGGCGGCG
ACGGCGACCGAGGCGTTGCTGCCGTTCGAGGACGCCCCACTGATCACCAACCCCGGCGGGCTCCTTGAGCAGGCCGTCGC
GGTCGAGGAGGCCATCGACACCGCCGCGGCGAACCAGTTGATGAACAATGTGCCCCAAGCGCTGCAACAACTGGCCCAGC
CCACGAAAAGCATCTGGCCGTTCGACCAACTGAGTGAACTCTGGAAAGCCATCTCGCCGCATCTGTCGCCGCTCAGCAAC
ATCGTGTCGATGCTCAACAACCACGTGTCGATGACCAACTCGGGTGTGTCGATGGCCAGCACCTTGCACTCGATGTTGAA
GGGCTTTGCTCCGGCGGCGGCTCAGGCCGTGGAAACCGCGGCGCAAAACGGGGTCCAGGCGATGAGCTCGCTGGGCAGCC
AGCTGGGTTCGTCGCTGGGTTCTTCGGGTCTGGGCGCTGGGGTGGCCGCCAACTTGGGTCGGGCGGCCTCGGTCGGTTCG
TTGTCGGTGCCGCAGGCCTGGGCCGCGGCCAACCAGGCGGTCACCCCGGCGGCGCGGGCGCTGCCGCTGACCAGCCTGAC
CAGCGCCGCCCAAACCGCCCCCGGACACATGCTGGGCGGGCTACCGCTGGGGCAACTGACCAATAGCGGCGGCGGGTTCG
GCGGGGTTAGCAATGCGTTGCGGATGCCGCCGCGGGCGTACGTAATGCCCCGTGTGCCCGCCGCCGGGTAA

Upstream 100 bases:

>100_bases
CATCTGGGGTTGTGACTACTTGAGAGAATTTGACCTGTTGCCGACGTTGTTTGCTGTCCATCATTGGTGCTAGTTATGGC
CGAGCGGAAGGATTATCGAA

Downstream 100 bases:

>100_bases
CGCCGATCCGCACGCAATGCGGGCCCTCTATGCGGGCAGCGATCTTGGTGGCCTCATCCACCGATGGCGCGCTCAACGGC
GAAAGTCCTGCAGTGCGGCG

Product: PPE family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MVDFGALPPEINSARMYAGPGSASLVAAAKMWDSVASDLFSAASAFQSVVWGLTTGSWIGSSAGLMVAAASPYVAWMSVT
AGQAELTAAQVRVAAAAYETAYGLTVPPPVIAENRAELMILIATNLLGQNTPAIAVNEAEYGEMWAQDAAAMFGYAATAA
TATEALLPFEDAPLITNPGGLLEQAVAVEEAIDTAAANQLMNNVPQALQQLAQPTKSIWPFDQLSELWKAISPHLSPLSN
IVSMLNNHVSMTNSGVSMASTLHSMLKGFAPAAAQAVETAAQNGVQAMSSLGSQLGSSLGSSGLGAGVAANLGRAASVGS
LSVPQAWAAANQAVTPAARALPLTSLTSAAQTAPGHMLGGLPLGQLTNSGGGFGGVSNALRMPPRAYVMPRVPAAG

Sequences:

>Translated_396_residues
MVDFGALPPEINSARMYAGPGSASLVAAAKMWDSVASDLFSAASAFQSVVWGLTTGSWIGSSAGLMVAAASPYVAWMSVT
AGQAELTAAQVRVAAAAYETAYGLTVPPPVIAENRAELMILIATNLLGQNTPAIAVNEAEYGEMWAQDAAAMFGYAATAA
TATEALLPFEDAPLITNPGGLLEQAVAVEEAIDTAAANQLMNNVPQALQQLAQPTKSIWPFDQLSELWKAISPHLSPLSN
IVSMLNNHVSMTNSGVSMASTLHSMLKGFAPAAAQAVETAAQNGVQAMSSLGSQLGSSLGSSGLGAGVAANLGRAASVGS
LSVPQAWAAANQAVTPAARALPLTSLTSAAQTAPGHMLGGLPLGQLTNSGGGFGGVSNALRMPPRAYVMPRVPAAG
>Mature_396_residues
MVDFGALPPEINSARMYAGPGSASLVAAAKMWDSVASDLFSAASAFQSVVWGLTTGSWIGSSAGLMVAAASPYVAWMSVT
AGQAELTAAQVRVAAAAYETAYGLTVPPPVIAENRAELMILIATNLLGQNTPAIAVNEAEYGEMWAQDAAAMFGYAATAA
TATEALLPFEDAPLITNPGGLLEQAVAVEEAIDTAAANQLMNNVPQALQQLAQPTKSIWPFDQLSELWKAISPHLSPLSN
IVSMLNNHVSMTNSGVSMASTLHSMLKGFAPAAAQAVETAAQNGVQAMSSLGSQLGSSLGSSGLGAGVAANLGRAASVGS
LSVPQAWAAANQAVTPAARALPLTSLTSAAQTAPGHMLGGLPLGQLTNSGGGFGGVSNALRMPPRAYVMPRVPAAG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mycobacterial PPE family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PPE19_MYCTU (Q11031)

Other databases:

- EMBL:   BX842576
- EMBL:   AE000516
- PIR:   H70741
- RefSeq:   NP_335855.1
- RefSeq:   YP_177801.1
- ProteinModelPortal:   Q11031
- SMR:   Q11031
- EnsemblBacteria:   EBMYCT00000000361
- EnsemblBacteria:   EBMYCT00000070165
- GeneID:   886819
- GeneID:   924490
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT1406
- KEGG:   mtu:Rv1361c
- TIGR:   MT1406
- TubercuList:   Rv1361c
- GeneTree:   EBGT00050000014887
- HOGENOM:   HBG572308
- OMA:   GMENTHL
- ProtClustDB:   CLSK799788
- InterPro:   IPR022171
- InterPro:   IPR000030

Pfam domain/function: PF12484 PE_PPE_C; PF00823 PPE

EC number: NA

Molecular weight: Translated: 40016; Mature: 40016

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: PS00501 SPASE_I_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVDFGALPPEINSARMYAGPGSASLVAAAKMWDSVASDLFSAASAFQSVVWGLTTGSWIG
CCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
SSAGLMVAAASPYVAWMSVTAGQAELTAAQVRVAAAAYETAYGLTVPPPVIAENRAELMI
CCCCEEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEE
LIATNLLGQNTPAIAVNEAEYGEMWAQDAAAMFGYAATAATATEALLPFEDAPLITNPGG
EEEHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCHH
LLEQAVAVEEAIDTAAANQLMNNVPQALQQLAQPTKSIWPFDQLSELWKAISPHLSPLSN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHH
IVSMLNNHVSMTNSGVSMASTLHSMLKGFAPAAAQAVETAAQNGVQAMSSLGSQLGSSLG
HHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SSGLGAGVAANLGRAASVGSLSVPQAWAAANQAVTPAARALPLTSLTSAAQTAPGHMLGG
CCCCCCHHHHHCCCCCCCCCCCCCHHHHHCCCCCCCHHHHCCHHHHHHHHHCCCCHHCCC
LPLGQLTNSGGGFGGVSNALRMPPRAYVMPRVPAAG
CCHHHHCCCCCCCCCHHHHHCCCCCCEECCCCCCCC
>Mature Secondary Structure
MVDFGALPPEINSARMYAGPGSASLVAAAKMWDSVASDLFSAASAFQSVVWGLTTGSWIG
CCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
SSAGLMVAAASPYVAWMSVTAGQAELTAAQVRVAAAAYETAYGLTVPPPVIAENRAELMI
CCCCEEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEE
LIATNLLGQNTPAIAVNEAEYGEMWAQDAAAMFGYAATAATATEALLPFEDAPLITNPGG
EEEHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCHH
LLEQAVAVEEAIDTAAANQLMNNVPQALQQLAQPTKSIWPFDQLSELWKAISPHLSPLSN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHH
IVSMLNNHVSMTNSGVSMASTLHSMLKGFAPAAAQAVETAAQNGVQAMSSLGSQLGSSLG
HHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SSGLGAGVAANLGRAASVGSLSVPQAWAAANQAVTPAARALPLTSLTSAAQTAPGHMLGG
CCCCCCHHHHHCCCCCCCCCCCCCHHHHHCCCCCCCHHHHCCHHHHHHHHHCCCCHHCCC
LPLGQLTNSGGGFGGVSNALRMPPRAYVMPRVPAAG
CCHHHHCCCCCCCCCHHHHHCCCCCCEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036