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The map label for this gene is cysM [H]

Identifier: 148822557

GI number: 148822557

Start: 1509494

End: 1510063

Strand: Direct

Name: cysM [H]

Synonym: TBFG_11366

Alternate gene names: 148822557

Gene position: 1509494-1510063 (Clockwise)

Preceding gene: 148822556

Following gene: 148822558

Centisome position: 34.12

GC content: 68.42

Gene sequence:

>570_bases
ATGCGATGGTGGCCCATGCGCGTCGCGACCACCCCGACGAAGCCTGCGGAGTGCTGGCCGGACCCGAGGGCTCTGACCGT
CCCGAGCGGCACCGGCCCCGAGCTGCTGGCCGACCTGCCCGAAATCACGCACTTCGTCGCCGGCCTAGGCACCACGGGCA
CGCTGATGGGCACTGGCCGTTTCCTGCGCGAGCACGTTGCCAACGTCAAGATCGTGGCGGCCGAACCCCGCTACGGTGAG
GGGGTATACGCCCTGCGCAACATGGACGAAGGCTTTGTGCCCGAGCTGTATGACCCGGAAATACTGACCGCGCGATATTC
TGTCGGCGCGGTGGACGCAGTGCGCCGCACCCGCGAGTTGGTGCACACCGAAGGCATCTTTGCGGGCATCTCAACCGGCG
CGGTGCTACACGCCGCACTCGGAGTCGGGGCCGGCGCCCTGGCGGCCGGCGAGCGGGCCGACATTGCGTTGGTGGTCGCC
GACGCCGGGTGGAAGTATCTGTCCACCGGCGCCTACGCCGGTAGCCTGGATGACGCCGAGACCGCTCTGGAAGGGCAACT
ATGGGCATGA

Upstream 100 bases:

>100_bases
CCTACCGTGACATGTTTCCCGGAGCATTCGGGTCCTGAAACTTCGGTGTTGCTTAGGAAAGGAACCGTCTACGTGCTGGT
GATTCGCGCAGACCTGGTGA

Downstream 100 bases:

>100_bases
CCCCGCGCCGGAAGCGACGGGGAGGAGCGGTGCAGATAACACGGCCCACAGGCCGTCCGCGAACACCGACAACGCAGACG
ACGAAGCGCCCGCGCTGGGT

Product: cysteine synthase B cysM

Products: NA

Alternate protein names: OPS sulfhydrylase; CysO-thiocarboxylate-dependent cysteine synthase; Cysteine synthase B; CSase B; O-phosphoserine-specific cysteine synthase [H]

Number of amino acids: Translated: 189; Mature: 189

Protein sequence:

>189_residues
MRWWPMRVATTPTKPAECWPDPRALTVPSGTGPELLADLPEITHFVAGLGTTGTLMGTGRFLREHVANVKIVAAEPRYGE
GVYALRNMDEGFVPELYDPEILTARYSVGAVDAVRRTRELVHTEGIFAGISTGAVLHAALGVGAGALAAGERADIALVVA
DAGWKYLSTGAYAGSLDDAETALEGQLWA

Sequences:

>Translated_189_residues
MRWWPMRVATTPTKPAECWPDPRALTVPSGTGPELLADLPEITHFVAGLGTTGTLMGTGRFLREHVANVKIVAAEPRYGE
GVYALRNMDEGFVPELYDPEILTARYSVGAVDAVRRTRELVHTEGIFAGISTGAVLHAALGVGAGALAAGERADIALVVA
DAGWKYLSTGAYAGSLDDAETALEGQLWA
>Mature_189_residues
MRWWPMRVATTPTKPAECWPDPRALTVPSGTGPELLADLPEITHFVAGLGTTGTLMGTGRFLREHVANVKIVAAEPRYGE
GVYALRNMDEGFVPELYDPEILTARYSVGAVDAVRRTRELVHTEGIFAGISTGAVLHAALGVGAGALAAGERADIALVVA
DAGWKYLSTGAYAGSLDDAETALEGQLWA

Specific function: Catalyzes the formation of a covalent CysO-cysteine adduct via a sulfur transfer, using the thiocarboxylated sulfur carrier protein CysO-COSH as sulfur donor and O-phospho-L-serine (OPS) as sulfur acceptor. Can also use sodium sulfide as sulfur donor in v

COG id: COG0031

COG function: function code E; Cysteine synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cysteine synthase/cystathionine beta- synthase family [H]

Homologues:

Organism=Escherichia coli, GI2367138, Length=143, Percent_Identity=34.965034965035, Blast_Score=86, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17535051, Length=157, Percent_Identity=29.9363057324841, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001216
- InterPro:   IPR005856
- InterPro:   IPR001926 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =2.5.1.65 [H]

Molecular weight: Translated: 20005; Mature: 20005

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRWWPMRVATTPTKPAECWPDPRALTVPSGTGPELLADLPEITHFVAGLGTTGTLMGTGR
CCEECCEEECCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCCEEHHHHH
FLREHVANVKIVAAEPRYGEGVYALRNMDEGFVPELYDPEILTARYSVGAVDAVRRTREL
HHHHHHCCEEEEEECCCCCCCEEEEECCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHH
VHTEGIFAGISTGAVLHAALGVGAGALAAGERADIALVVADAGWKYLSTGAYAGSLDDAE
HHHCCHHCCCHHHHHHHHHHHCCCCHHCCCCCCCEEEEEECCCCEEEECCCCCCCCCCHH
TALEGQLWA
HHHCCCCCC
>Mature Secondary Structure
MRWWPMRVATTPTKPAECWPDPRALTVPSGTGPELLADLPEITHFVAGLGTTGTLMGTGR
CCEECCEEECCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCCEEHHHHH
FLREHVANVKIVAAEPRYGEGVYALRNMDEGFVPELYDPEILTARYSVGAVDAVRRTREL
HHHHHHCCEEEEEECCCCCCCEEEEECCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHH
VHTEGIFAGISTGAVLHAALGVGAGALAAGERADIALVVADAGWKYLSTGAYAGSLDDAE
HHHCCHHCCCHHHHHHHHHHHCCCCHHCCCCCCCEEEEEECCCCEEEECCCCCCCCCCHH
TALEGQLWA
HHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]