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The map label for this gene is 148822536

Identifier: 148822536

GI number: 148822536

Start: 1482966

End: 1484591

Strand: Reverse

Name: 148822536

Synonym: TBFG_11345

Alternate gene names: NA

Gene position: 1484591-1482966 (Counterclockwise)

Preceding gene: 148822537

Following gene: 148822535

Centisome position: 33.55

GC content: 66.05

Gene sequence:

>1626_bases
ATGTCGGCCAAGAAGAGCACGGCGCAACGCTTGGGTCGGGTGCTGGAGACGGTGACCCGGCAGAGCGGCCGGCTGCCAGA
AACTCCCGCGTACGGCTCCTGGCTGCTTGGGCGGGTTTCGGAAAGCCAACGGCGCCGACGGGTACGGATCCAGGTCATGC
TGACCGCGCTGGTCGTGACCGCGAACCTGCTCGGCATCGGGGTTGCCCTGCTATTGGTGACGATCGCCATCCCCGAACCG
AGCATCGTTCGCGACACGCCACGGTGGCTCACGTTCGGGGTGGTACCGGGCTATGTCCTGCTAGCCCTCGCTTTGGGTAG
CTACGCACTGACCAGGCAGACCGTGCAAGCCCTGCGCTGGGCGATCGAAGGACGGAAACCGACTCGTGAGGAGGAGCGCC
GCACCTTCCTGGCCCCCTGGCGAGTCGCCGTGGGCCACCTCATGTTCTGGGGTGTTGGCACGGCGCTCTTGACGACACTC
TACGGCCTGATCAACAACGCGTTCATCCCGCGATTCCTGTTCGCGGTCAGCTTTTGCGGCGTATTGGTCGCAACCGCAAC
CTATCTGCATACCGAGTTCGCATTGCGCCCGTTCGCCGCCCAGGCGCTCGAGGCCGGGCCGCCGCCACGCCGGTTGGCGC
CGGGAATCCTGGGCCGGACCATGGTGGTGTGGCTGCTCGGTTCGGGAGTACCCGTCGTCGGCATCGCCCTGATGGCGATG
TTCGAAATGGTGCTGCTCAATCTCACTCGGATGCAGTTCGCGACGGGCGTGCTGATCATCTCGATGGTCACATTGGTGTT
AGGGTTCATCCTGATGTGGATCCTGGCCTGGCTGACGGCGACCCCGGTGCGGGTGGTGCGTGCGGCGCTGCGGCGCGTCG
AGCGGGGCGAGCTACGGACCAACCTGGTGGTCTTCGACGGCACCGAACTCGGCGAGCTGCAGCGTGGTTTCAACGCGATG
GTCGCCGGACTGCGGGAGCGCGAACGAGTGCGCGATCTGTTCGGCCGCCACGTCGGACGCGAAGTCGCCGCCGCCGCCGA
GCGTGAACGTTCGAAACTGGGCGGCGAAGAACGCCACGTCGCCGTCGTGTTCATCGACATCGTCGGCTCGACGCAATTGG
TGACCAGCCGGCCGCCGGCCGACGTCGTCAAGCTGCTCAACAAGTTCTTCGCGATTGTCGTCGACGAGGTCGACCGCCAC
CACGGATTGGTCAACAAGTTCGAGGGGGACGCGTCGCTAACCATCTTCGGCGCCCCGAACCGGCTTCCCTGTCCCGAAGA
CAAGGCACTGGCCGCCGCGCGGGCGATAGCCGATCGGCTGGTCAACGAAATGCCCGAGTGCCAGGCCGGGATCGGCGTGG
CGGCGGGGCAGGTCATTGCCGGCAACGTGGGTGCCCGAGAACGGTTCGAGTACACCGTGATCGGGGAGCCGGTCAACGAG
GCGGCCCGATTGTGCGAACTGGCCAAATCGCGTCCCGGCAAGTTGCTGGCTTCGGCACAGGCCGTGGACGCCGCAAGCGA
AGAGGAGCGCGCCCGTTGGTCTTTGGGTAGGCATGTGAAACTTCGTGGGCACGACCAACCGGTCCGGCTGGCCAAGCCGG
TCGGGCTGACCAAGCCGCGTAGGTAA

Upstream 100 bases:

>100_bases
GCAGCCGACTCGGCTGGCCGTGCCCACCTAAGCCGGGCAAACAACACGAGCGCGCCAACCGGTCGCACCCGACTCTTCGA
CAAACTAGTCTGACGCCACA

Downstream 100 bases:

>100_bases
CCTGCCCGAACCCACGACGACCCCATCACAATGTCGTTTTTCCGCCAGTCATGTCGGTGGGCGGGTGTAATTGTTGAAGG
GTGCACGACGACTTCGAACG

Product: adenylate cyclase

Products: 3',5'-cyclic AMP; diphosphate

Alternate protein names: NA

Number of amino acids: Translated: 541; Mature: 540

Protein sequence:

>541_residues
MSAKKSTAQRLGRVLETVTRQSGRLPETPAYGSWLLGRVSESQRRRRVRIQVMLTALVVTANLLGIGVALLLVTIAIPEP
SIVRDTPRWLTFGVVPGYVLLALALGSYALTRQTVQALRWAIEGRKPTREEERRTFLAPWRVAVGHLMFWGVGTALLTTL
YGLINNAFIPRFLFAVSFCGVLVATATYLHTEFALRPFAAQALEAGPPPRRLAPGILGRTMVVWLLGSGVPVVGIALMAM
FEMVLLNLTRMQFATGVLIISMVTLVLGFILMWILAWLTATPVRVVRAALRRVERGELRTNLVVFDGTELGELQRGFNAM
VAGLRERERVRDLFGRHVGREVAAAAERERSKLGGEERHVAVVFIDIVGSTQLVTSRPPADVVKLLNKFFAIVVDEVDRH
HGLVNKFEGDASLTIFGAPNRLPCPEDKALAAARAIADRLVNEMPECQAGIGVAAGQVIAGNVGARERFEYTVIGEPVNE
AARLCELAKSRPGKLLASAQAVDAASEEERARWSLGRHVKLRGHDQPVRLAKPVGLTKPRR

Sequences:

>Translated_541_residues
MSAKKSTAQRLGRVLETVTRQSGRLPETPAYGSWLLGRVSESQRRRRVRIQVMLTALVVTANLLGIGVALLLVTIAIPEP
SIVRDTPRWLTFGVVPGYVLLALALGSYALTRQTVQALRWAIEGRKPTREEERRTFLAPWRVAVGHLMFWGVGTALLTTL
YGLINNAFIPRFLFAVSFCGVLVATATYLHTEFALRPFAAQALEAGPPPRRLAPGILGRTMVVWLLGSGVPVVGIALMAM
FEMVLLNLTRMQFATGVLIISMVTLVLGFILMWILAWLTATPVRVVRAALRRVERGELRTNLVVFDGTELGELQRGFNAM
VAGLRERERVRDLFGRHVGREVAAAAERERSKLGGEERHVAVVFIDIVGSTQLVTSRPPADVVKLLNKFFAIVVDEVDRH
HGLVNKFEGDASLTIFGAPNRLPCPEDKALAAARAIADRLVNEMPECQAGIGVAAGQVIAGNVGARERFEYTVIGEPVNE
AARLCELAKSRPGKLLASAQAVDAASEEERARWSLGRHVKLRGHDQPVRLAKPVGLTKPRR
>Mature_540_residues
SAKKSTAQRLGRVLETVTRQSGRLPETPAYGSWLLGRVSESQRRRRVRIQVMLTALVVTANLLGIGVALLLVTIAIPEPS
IVRDTPRWLTFGVVPGYVLLALALGSYALTRQTVQALRWAIEGRKPTREEERRTFLAPWRVAVGHLMFWGVGTALLTTLY
GLINNAFIPRFLFAVSFCGVLVATATYLHTEFALRPFAAQALEAGPPPRRLAPGILGRTMVVWLLGSGVPVVGIALMAMF
EMVLLNLTRMQFATGVLIISMVTLVLGFILMWILAWLTATPVRVVRAALRRVERGELRTNLVVFDGTELGELQRGFNAMV
AGLRERERVRDLFGRHVGREVAAAAERERSKLGGEERHVAVVFIDIVGSTQLVTSRPPADVVKLLNKFFAIVVDEVDRHH
GLVNKFEGDASLTIFGAPNRLPCPEDKALAAARAIADRLVNEMPECQAGIGVAAGQVIAGNVGARERFEYTVIGEPVNEA
ARLCELAKSRPGKLLASAQAVDAASEEERARWSLGRHVKLRGHDQPVRLAKPVGLTKPRR

Specific function: Unknown

COG id: COG2114

COG function: function code T; Adenylate cyclase, family 3 (some proteins contain HAMP domain)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HAMP domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00211 Guanylate_cyc; PF00672 HAMP [H]

EC number: 4.6.1.1

Molecular weight: Translated: 59299; Mature: 59167

Theoretical pI: Translated: 11.23; Mature: 11.23

Prosite motif: PS50885 HAMP ; PS50125 GUANYLATE_CYCLASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAKKSTAQRLGRVLETVTRQSGRLPETPAYGSWLLGRVSESQRRRRVRIQVMLTALVVT
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ANLLGIGVALLLVTIAIPEPSIVRDTPRWLTFGVVPGYVLLALALGSYALTRQTVQALRW
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIEGRKPTREEERRTFLAPWRVAVGHLMFWGVGTALLTTLYGLINNAFIPRFLFAVSFCG
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLVATATYLHTEFALRPFAAQALEAGPPPRRLAPGILGRTMVVWLLGSGVPVVGIALMAM
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHH
FEMVLLNLTRMQFATGVLIISMVTLVLGFILMWILAWLTATPVRVVRAALRRVERGELRT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHE
NLVVFDGTELGELQRGFNAMVAGLRERERVRDLFGRHVGREVAAAAERERSKLGGEERHV
EEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
AVVFIDIVGSTQLVTSRPPADVVKLLNKFFAIVVDEVDRHHGLVNKFEGDASLTIFGAPN
EEEEEEECCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCEEEEEECCC
RLPCPEDKALAAARAIADRLVNEMPECQAGIGVAAGQVIAGNVGARERFEYTVIGEPVNE
CCCCCCHHHHHHHHHHHHHHHHHCCHHHHCCCHHCCCEEECCCCCCCCEEEEEECCCHHH
AARLCELAKSRPGKLLASAQAVDAASEEERARWSLGRHVKLRGHDQPVRLAKPVGLTKPR
HHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHCCCEEEECCCCCCCHHCCCCCCCCCC
R
C
>Mature Secondary Structure 
SAKKSTAQRLGRVLETVTRQSGRLPETPAYGSWLLGRVSESQRRRRVRIQVMLTALVVT
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ANLLGIGVALLLVTIAIPEPSIVRDTPRWLTFGVVPGYVLLALALGSYALTRQTVQALRW
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIEGRKPTREEERRTFLAPWRVAVGHLMFWGVGTALLTTLYGLINNAFIPRFLFAVSFCG
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLVATATYLHTEFALRPFAAQALEAGPPPRRLAPGILGRTMVVWLLGSGVPVVGIALMAM
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHH
FEMVLLNLTRMQFATGVLIISMVTLVLGFILMWILAWLTATPVRVVRAALRRVERGELRT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHE
NLVVFDGTELGELQRGFNAMVAGLRERERVRDLFGRHVGREVAAAAERERSKLGGEERHV
EEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
AVVFIDIVGSTQLVTSRPPADVVKLLNKFFAIVVDEVDRHHGLVNKFEGDASLTIFGAPN
EEEEEEECCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCEEEEEECCC
RLPCPEDKALAAARAIADRLVNEMPECQAGIGVAAGQVIAGNVGARERFEYTVIGEPVNE
CCCCCCHHHHHHHHHHHHHHHHHCCHHHHCCCHHCCCEEECCCCCCCCEEEEEECCCHHH
AARLCELAKSRPGKLLASAQAVDAASEEERARWSLGRHVKLRGHDQPVRLAKPVGLTKPR
HHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHCCCEEEECCCCCCCHHCCCCCCCCCC
R
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP

Specific reaction: ATP = 3',5'-cyclic AMP + diphosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]