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The map label for this gene is 148822164

Identifier: 148822164

GI number: 148822164

Start: 1069901

End: 1071268

Strand: Direct

Name: 148822164

Synonym: TBFG_10973

Alternate gene names: NA

Gene position: 1069901-1071268 (Clockwise)

Preceding gene: 148822163

Following gene: 148822165

Centisome position: 24.18

GC content: 67.69

Gene sequence:

>1368_bases
GTGAACAGGGTGTCAGCAAGCGCGGACGATCGGGCGGCCGGCGCTCGTCCAGCTCGCGACCTCGTCAGGGTTGCGTTCGG
CCCAGGTGTGGTGGCGTTGGGCATCATCGCCGCGGTGACGCTGCTCCAATTGCTGATCGCCAATAGCGACATGACCGGTG
CGTGGGGCGCCATCGCCAGCATGTGGCTGGGCGTGCACCTGGTGCCGATCTCGATCGGTGGCCGCGCACTGGGCGTCATG
CCGCTGTTGCCGGTCCTGTTGATGGTGTGGGCCACCGCGCGCAGCACGGCGCGGGCCACATCCCCACAGTCGTCAGGGCT
CGTTGTTCGCTGGGTCGTCGCGTCGGCCCTGGGCGGACCGCTGCTGATGGCGGCGATTGCCCTGGCGGTCATTCACGACG
CGTCATCAGTGGTCACCGAGCTGCAGACGCCCAGCGCCCTGCGCGCGTTCACTAGTGTGCTGGTTGTGCATTCCGTTGGG
GCCGCGACCGGGGTGTGGTCCCGGGTAGGTCGACGGGCGCTAGCCGCCACGGCACTGCCCGATTGGCTGCATGATTCGAT
GCGTGCCGCCGCCGCTGGGGTGCTGGCGTTGCTCGGGCTTTCCGGCGTGGTGACGGCGGGGTCGCTGGTTGTGCATTGGG
CGACGATGCAAGAGCTCTACGGGATCACCGATTCGATATTCGGCCAGTTCAGCCTCACTGTACTTTCGGTGCTTTACGCA
CCCAACGTCATCGTCGGCACCTCGGCCATCGCGGTTGGGTCCAGTGCTCACATTGGCTTCGCGACGTTCAGTTCGTTTGC
AGTTTTGGGCGGCGATATCCCGGCACTGCCGATCCTGGCCGCGGCCCCGACGCCGCCGCTCGGCCCGGCATGGGTTGCCT
TACTCATTGTGGGTGCTTCGTCGGGTGTGGCGGTCGGTCAGCAGTGCGCCCGCCGCGCCCTGCCGTTTGTTGCGGCTATG
GCCAAGCTGCTGGTCGCTGCCGTTGCCGGGGCATTGGTAATGGCGGTTCTGGGTTACGGCGGTGGCGGCCGGCTGGGCAA
TTTCGGCGATGTCGGCGTGGACGAGGGCGCCTTGGTGTTGGGCGTGCTCTTCTGGTTTACGTTCGTAGGATGGGTCACGG
TGGTGATTGCCGGCGGGATCAGCCGCCGCCCCAAGCGGCTCCGGCCGGCCCCGCCGGTCGAGCTGGACGCCGATGAATCT
TCGCCACCGGTAGACATGTTCGACGGGGCAGCGAGCGAGCAGCCGCCCGCTTCGGTCGCGGAAGACGTCCCGCCTAGCCA
CGACGACATCGCCAACGGCCTCAAGGCCCCTACTGCCGACGACGAGGCGCTGCCCTTGTCCGACGAACCGCCGCCGCGGG
CCGACTAA

Upstream 100 bases:

>100_bases
CAACTATTCAAACCCCAGCGGGGGCGAGCAGTCGTCGTCCCCCGGGGGGGCGCCGGTCTAACCGGGCGTTCCCGCGTCCG
GTCGCGCGTGTGCGCGAAGA

Downstream 100 bases:

>100_bases
TCTGCGGTTGGTGAGGCCGCAACTGTCTGAGGCCTTTACTCACGGTACTGAGTCTGCACTGGGATGCAGGCTGGTGGTGC
TCACACGCTTTGAGGAGCCA

Product: integral membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 455; Mature: 455

Protein sequence:

>455_residues
MNRVSASADDRAAGARPARDLVRVAFGPGVVALGIIAAVTLLQLLIANSDMTGAWGAIASMWLGVHLVPISIGGRALGVM
PLLPVLLMVWATARSTARATSPQSSGLVVRWVVASALGGPLLMAAIALAVIHDASSVVTELQTPSALRAFTSVLVVHSVG
AATGVWSRVGRRALAATALPDWLHDSMRAAAAGVLALLGLSGVVTAGSLVVHWATMQELYGITDSIFGQFSLTVLSVLYA
PNVIVGTSAIAVGSSAHIGFATFSSFAVLGGDIPALPILAAAPTPPLGPAWVALLIVGASSGVAVGQQCARRALPFVAAM
AKLLVAAVAGALVMAVLGYGGGGRLGNFGDVGVDEGALVLGVLFWFTFVGWVTVVIAGGISRRPKRLRPAPPVELDADES
SPPVDMFDGAASEQPPASVAEDVPPSHDDIANGLKAPTADDEALPLSDEPPPRAD

Sequences:

>Translated_455_residues
MNRVSASADDRAAGARPARDLVRVAFGPGVVALGIIAAVTLLQLLIANSDMTGAWGAIASMWLGVHLVPISIGGRALGVM
PLLPVLLMVWATARSTARATSPQSSGLVVRWVVASALGGPLLMAAIALAVIHDASSVVTELQTPSALRAFTSVLVVHSVG
AATGVWSRVGRRALAATALPDWLHDSMRAAAAGVLALLGLSGVVTAGSLVVHWATMQELYGITDSIFGQFSLTVLSVLYA
PNVIVGTSAIAVGSSAHIGFATFSSFAVLGGDIPALPILAAAPTPPLGPAWVALLIVGASSGVAVGQQCARRALPFVAAM
AKLLVAAVAGALVMAVLGYGGGGRLGNFGDVGVDEGALVLGVLFWFTFVGWVTVVIAGGISRRPKRLRPAPPVELDADES
SPPVDMFDGAASEQPPASVAEDVPPSHDDIANGLKAPTADDEALPLSDEPPPRAD
>Mature_455_residues
MNRVSASADDRAAGARPARDLVRVAFGPGVVALGIIAAVTLLQLLIANSDMTGAWGAIASMWLGVHLVPISIGGRALGVM
PLLPVLLMVWATARSTARATSPQSSGLVVRWVVASALGGPLLMAAIALAVIHDASSVVTELQTPSALRAFTSVLVVHSVG
AATGVWSRVGRRALAATALPDWLHDSMRAAAAGVLALLGLSGVVTAGSLVVHWATMQELYGITDSIFGQFSLTVLSVLYA
PNVIVGTSAIAVGSSAHIGFATFSSFAVLGGDIPALPILAAAPTPPLGPAWVALLIVGASSGVAVGQQCARRALPFVAAM
AKLLVAAVAGALVMAVLGYGGGGRLGNFGDVGVDEGALVLGVLFWFTFVGWVTVVIAGGISRRPKRLRPAPPVELDADES
SPPVDMFDGAASEQPPASVAEDVPPSHDDIANGLKAPTADDEALPLSDEPPPRAD

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y955_MYCTU (P64771)

Other databases:

- EMBL:   BX842575
- EMBL:   AE000516
- PIR:   A70717
- RefSeq:   NP_215470.1
- RefSeq:   NP_335416.1
- EnsemblBacteria:   EBMYCT00000000123
- EnsemblBacteria:   EBMYCT00000072624
- GeneID:   885408
- GeneID:   926374
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT0982
- KEGG:   mtu:Rv0955
- TIGR:   MT0982
- TubercuList:   Rv0955
- GeneTree:   EBGT00050000015370
- HOGENOM:   HBG565094
- OMA:   AICLAVI
- ProtClustDB:   CLSK790853
- GO:   GO:0040007

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 46089; Mature: 46089

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1970b49c)-; HASH(0x199407fc)-; HASH(0x18f3564c)-; HASH(0x198e62ac)-; HASH(0x19671314)-; HASH(0x18bc5650)-; HASH(0x18abd2f4)-; HASH(0x187a0028)-; HASH(0x18a26c68)-; HASH(0x166f953c)-; HASH(0x19297c04)-;

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRVSASADDRAAGARPARDLVRVAFGPGVVALGIIAAVTLLQLLIANSDMTGAWGAIAS
CCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
MWLGVHLVPISIGGRALGVMPLLPVLLMVWATARSTARATSPQSSGLVVRWVVASALGGP
HHHHHEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCHH
LLMAAIALAVIHDASSVVTELQTPSALRAFTSVLVVHSVGAATGVWSRVGRRALAATALP
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
DWLHDSMRAAAAGVLALLGLSGVVTAGSLVVHWATMQELYGITDSIFGQFSLTVLSVLYA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHC
PNVIVGTSAIAVGSSAHIGFATFSSFAVLGGDIPALPILAAAPTPPLGPAWVALLIVGAS
CCEEECCCHHEECCCCCCHHHHHHHHHHHCCCCCCCCEEECCCCCCCCHHHHHHHHHCCC
SGVAVGQQCARRALPFVAAMAKLLVAAVAGALVMAVLGYGGGGRLGNFGDVGVDEGALVL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHH
GVLFWFTFVGWVTVVIAGGISRRPKRLRPAPPVELDADESSPPVDMFDGAASEQPPASVA
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEECCCCCCCCCHHHCCCCCCCCCCHHH
EDVPPSHDDIANGLKAPTADDEALPLSDEPPPRAD
HCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCH
>Mature Secondary Structure
MNRVSASADDRAAGARPARDLVRVAFGPGVVALGIIAAVTLLQLLIANSDMTGAWGAIAS
CCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
MWLGVHLVPISIGGRALGVMPLLPVLLMVWATARSTARATSPQSSGLVVRWVVASALGGP
HHHHHEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCHH
LLMAAIALAVIHDASSVVTELQTPSALRAFTSVLVVHSVGAATGVWSRVGRRALAATALP
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
DWLHDSMRAAAAGVLALLGLSGVVTAGSLVVHWATMQELYGITDSIFGQFSLTVLSVLYA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHC
PNVIVGTSAIAVGSSAHIGFATFSSFAVLGGDIPALPILAAAPTPPLGPAWVALLIVGAS
CCEEECCCHHEECCCCCCHHHHHHHHHHHCCCCCCCCEEECCCCCCCCHHHHHHHHHCCC
SGVAVGQQCARRALPFVAAMAKLLVAAVAGALVMAVLGYGGGGRLGNFGDVGVDEGALVL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHH
GVLFWFTFVGWVTVVIAGGISRRPKRLRPAPPVELDADESSPPVDMFDGAASEQPPASVA
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEECCCCCCCCCHHHCCCCCCCCCCHHH
EDVPPSHDDIANGLKAPTADDEALPLSDEPPPRAD
HCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036