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The map label for this gene is pstA1

Identifier: 148822139

GI number: 148822139

Start: 1040825

End: 1041739

Strand: Direct

Name: pstA1

Synonym: TBFG_10948

Alternate gene names: 148822139

Gene position: 1040825-1041739 (Clockwise)

Preceding gene: 148822138

Following gene: 148822142

Centisome position: 23.52

GC content: 63.39

Gene sequence:

>915_bases
GTGAGTCCCTCAACGAGCATCGAGGCGCTCGACCAGCCGGTAAAGCCGGTGGTGTTTCGTCCGCTTACGCTGCGACGGCG
GATCAAAAACAGCGTCGCGACAACGTTTTTCTTCACCTCGTTCGTGGTCGCGTTGATACCGTTGGTCTGGCTGCTTTGGG
TGGTGATTGCCCGGGGTTGGTTTGCCGTCACCCGATCGGGCTGGTGGACCCACTCGCTGCGCGGCGTGCTGCCAGAGCAA
TTCGCCGGTGGGGTGTATCACGCCCTGTACGGCACGCTGGTGCAGGCCGGGGTGGCCGCCGTGCTGGCCGTGCCGCTGGG
CTTGATGACCGCGGTTTACCTAGTGGAATACGGGACTGGTCGAATGTCGCGGGTGACTACCTTCACCGTCGACGTGCTTG
CCGGCGTGCCCTCTATCGTGGCGGCGTTATTCGTCTTCAGCCTGTGGATCGCCACCCTAGGATTTCAGCAGAGCGCCTTT
GCCGTGGCGTTGGCGTTGGTCCTGCTGATGTTGCCGGTGGTGGTTCGGGCAGGCGAGGAGATGCTCAGGTTGGTGCCCGA
TGAACTGCGAGAAGCCAGCTACGCGTTAGGCGTTCCGAAATGGAAGACGATCGTGCGGATCGTCGCCCCGATCGCGATGC
CGGGCATCGTGTCAGGCATCTTGTTGTCCATCGCGCGCGTCGTCGGTGAAACCGCACCGGTTCTGGTGCTGGTCGGGTAC
AGCCACTCCATCAACCTCGACGTCTTCCACGGCAACATGGCCTCGCTGCCGTTGCTGATCTACACCGAACTCACCAATCC
CGAGCACGCCGGCTTCCTGCGCGTCTGGGGCGCGGCGCTGACCCTGATCATCGTGGTCGCCACGATCAACCTGGCCGCGG
CGATGATCCGGTTCGTCGCAACCCGACGGCGGTGA

Upstream 100 bases:

>100_bases
TGCCGACCGGAGCCTATATTTCGGCGGGATTTGCGTTATTCGTGCTGACGTTCCTGGTCAATGCGGCCGCTCGCGCAATC
GCCGGCGGGAAGGTCAACGG

Downstream 100 bases:

>100_bases
CTCCCGTTATGACGTGAGTTTCACCACTCGGTCGTTGCCGCGGTCGGCGACGTAGACGGTCCGGTCGCTGTCCACTGCCA
CCGCGAGGGGGGTGTTGAGG

Product: phosphate-transport system integral membrane ABC transporter pstA1

Products: ADP; phosphate [Cytoplasm]; phosphate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 303

Protein sequence:

>304_residues
MSPSTSIEALDQPVKPVVFRPLTLRRRIKNSVATTFFFTSFVVALIPLVWLLWVVIARGWFAVTRSGWWTHSLRGVLPEQ
FAGGVYHALYGTLVQAGVAAVLAVPLGLMTAVYLVEYGTGRMSRVTTFTVDVLAGVPSIVAALFVFSLWIATLGFQQSAF
AVALALVLLMLPVVVRAGEEMLRLVPDELREASYALGVPKWKTIVRIVAPIAMPGIVSGILLSIARVVGETAPVLVLVGY
SHSINLDVFHGNMASLPLLIYTELTNPEHAGFLRVWGAALTLIIVVATINLAAAMIRFVATRRR

Sequences:

>Translated_304_residues
MSPSTSIEALDQPVKPVVFRPLTLRRRIKNSVATTFFFTSFVVALIPLVWLLWVVIARGWFAVTRSGWWTHSLRGVLPEQ
FAGGVYHALYGTLVQAGVAAVLAVPLGLMTAVYLVEYGTGRMSRVTTFTVDVLAGVPSIVAALFVFSLWIATLGFQQSAF
AVALALVLLMLPVVVRAGEEMLRLVPDELREASYALGVPKWKTIVRIVAPIAMPGIVSGILLSIARVVGETAPVLVLVGY
SHSINLDVFHGNMASLPLLIYTELTNPEHAGFLRVWGAALTLIIVVATINLAAAMIRFVATRRR
>Mature_303_residues
SPSTSIEALDQPVKPVVFRPLTLRRRIKNSVATTFFFTSFVVALIPLVWLLWVVIARGWFAVTRSGWWTHSLRGVLPEQF
AGGVYHALYGTLVQAGVAAVLAVPLGLMTAVYLVEYGTGRMSRVTTFTVDVLAGVPSIVAALFVFSLWIATLGFQQSAFA
VALALVLLMLPVVVRAGEEMLRLVPDELREASYALGVPKWKTIVRIVAPIAMPGIVSGILLSIARVVGETAPVLVLVGYS
HSINLDVFHGNMASLPLLIYTELTNPEHAGFLRVWGAALTLIIVVATINLAAAMIRFVATRRR

Specific function: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane

COG id: COG0581

COG function: function code P; ABC-type phosphate transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain

Homologues:

Organism=Escherichia coli, GI1790163, Length=275, Percent_Identity=36, Blast_Score=147, Evalue=6e-37,
Organism=Escherichia coli, GI1790164, Length=190, Percent_Identity=27.8947368421053, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PSTA1_MYCTU (O86345)

Other databases:

- EMBL:   X75297
- EMBL:   BX842575
- EMBL:   AE000516
- PIR:   B70584
- RefSeq:   NP_215445.2
- RefSeq:   NP_335390.1
- ProteinModelPortal:   O86345
- SMR:   O86345
- EnsemblBacteria:   EBMYCT00000000501
- EnsemblBacteria:   EBMYCT00000069341
- GeneID:   885589
- GeneID:   926273
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT0957
- KEGG:   mtu:Rv0930
- TIGR:   MT0957
- TubercuList:   Rv0930
- GeneTree:   EBGT00050000015074
- HOGENOM:   HBG705496
- OMA:   ITFFVDV
- ProtClustDB:   CLSK881166
- InterPro:   IPR000515
- InterPro:   IPR005672
- TIGRFAMs:   TIGR00974

Pfam domain/function: PF00528 BPD_transp_1

EC number: NA

Molecular weight: Translated: 32989; Mature: 32858

Theoretical pI: Translated: 10.76; Mature: 10.76

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1852bea0)-; HASH(0x193c1204)-; HASH(0x196b1cf4)-; HASH(0x186992ec)-; HASH(0x1988fcec)-; HASH(0x196dd5dc)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPSTSIEALDQPVKPVVFRPLTLRRRIKNSVATTFFFTSFVVALIPLVWLLWVVIARGW
CCCCCCHHHHCCCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
FAVTRSGWWTHSLRGVLPEQFAGGVYHALYGTLVQAGVAAVLAVPLGLMTAVYLVEYGTG
HHHHCCCCHHHHHHCCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
RMSRVTTFTVDVLAGVPSIVAALFVFSLWIATLGFQQSAFAVALALVLLMLPVVVRAGEE
CCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHH
MLRLVPDELREASYALGVPKWKTIVRIVAPIAMPGIVSGILLSIARVVGETAPVLVLVGY
HHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEC
SHSINLDVFHGNMASLPLLIYTELTNPEHAGFLRVWGAALTLIIVVATINLAAAMIRFVA
CCEEEEEEEECCHHHCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TRRR
HCCH
>Mature Secondary Structure 
SPSTSIEALDQPVKPVVFRPLTLRRRIKNSVATTFFFTSFVVALIPLVWLLWVVIARGW
CCCCCHHHHCCCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
FAVTRSGWWTHSLRGVLPEQFAGGVYHALYGTLVQAGVAAVLAVPLGLMTAVYLVEYGTG
HHHHCCCCHHHHHHCCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
RMSRVTTFTVDVLAGVPSIVAALFVFSLWIATLGFQQSAFAVALALVLLMLPVVVRAGEE
CCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHH
MLRLVPDELREASYALGVPKWKTIVRIVAPIAMPGIVSGILLSIARVVGETAPVLVLVGY
HHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEC
SHSINLDVFHGNMASLPLLIYTELTNPEHAGFLRVWGAALTLIIVVATINLAAAMIRFVA
CCEEEEEEEECCHHHCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TRRR
HCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; phosphate [Periplasm]; H2O [C]

Specific reaction: ATP + phosphate [Periplasm] + H2O = ADP + phosphate [Cytoplasm] + phosphate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8112854; 8843165; 9634230; 12368430; 12218036