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The map label for this gene is ftsW

Identifier: 148821208

GI number: 148821208

Start: 20332

End: 21741

Strand: Reverse

Name: ftsW

Synonym: TBFG_10017

Alternate gene names: 148821208

Gene position: 21741-20332 (Counterclockwise)

Preceding gene: 148821209

Following gene: 148821207

Centisome position: 0.49

GC content: 62.13

Gene sequence:

>1410_bases
ATGACGACACGACTGCAAGCGCCGGTGGCCGTAACGCCCCCGTTGCCGACTCGGCGCAACGCTGAACTGCTGCTGCTGTG
CTTTGCCGCCGTAATCACGTTTGCCGCACTGCTGGTCGTGCAGGCCAATCAAGACCAGGGGGTGCCCTGGGACTTGACTA
GCTACGGACTGGCCTTCCTGACCCTGTTCGGATCCGCGCATCTGGCCATCCGGCGCTTCGCCCCCTACACTGACCCGCTG
TTGCTCCCGGTGGTGGCACTGCTCAACGGACTTGGCCTGGTAATGATCCACCGCCTCGATCTGGTGGACAACGAGATCGG
CGAGCATCGGCACCCCAGCGCAAACCAGCAGATGCTGTGGACGCTGGTGGGCGTAGCTGCCTTCGCGCTCGTGGTGACCT
TCCTCAAGGACCACCGACAGCTCGCACGCTACGGCTACATTTGCGGGCTCGCGGGTCTGGTTTTCTTGGCAGTTCCCGCG
CTGCTCCCGGCAGCACTGTCCGAACAGAACGGCGCCAAGATCTGGATCCGGTTGCCCGGCTTCTCGATTCAACCCGCCGA
ATTTTCAAAGATTCTGCTGCTGATCTTCTTTTCGGCGGTACTGGTGGCCAAACGCGGCCTGTTCACCAGCGCCGGCAAAC
ATTTGCTCGGAATGACCCTGCCGCGCCCGCGAGACCTCGCGCCACTGTTGGCAGCCTGGGTCATCTCGGTGGGTGTGATG
GTCTTCGAGAAAGACCTCGGCGCTTCGCTGCTGCTGTACACATCGTTTCTGGTGGTGGTTTACCTCGCCACCCAGCGGTT
CAGTTGGGTCGTCATCGGCCTGACTCTGTTCGCGGCAGGAACCTTGGTGGCGTACTTCATTTTTGAGCACGTCCGGCTCC
GCGTACAGACCTGGCTGGATCCGTTCGCAGATCCAGACGGCACCGGATATCAGATCGTGCAGTCGCTTTTCAGCTTCGCT
ACAGGCGGTATCTTCGGCACCGGGCTCGGTAATGGTCAACCCGACACCGTGCCCGCGGCATCCACCGATTTCATCATCGC
CGCGTTCGGCGAAGAGCTTGGGTTGGTGGGCTTGACGGCCATCCTGATGCTCTACACCATCGTGATCATCCGGGGTTTGC
GCACGGCCATCGCCACCCGCGATAGCTTCGGCAAGCTGCTGGCCGCCGGCCTCTCATCGACGCTAGCCATTCAGCTGTTC
ATCGTCGTCGGCGGTGTGACCCGACTCATTCCGCTGACCGGGTTGACCACACCGTGGATGTCCTACGGCGGGTCTTCACT
GCTGGCCAACTACATATTGCTGGCCATCCTGGCACGCATCTCGCACGGAGCCCGCCGCCCACTGCGCACCCGCCCACGAA
ATAAGTCGCCGATTACGGCGGCCGGCACCGAGGTCATCGAACGCGTATGA

Upstream 100 bases:

>100_bases
CCGCGTCGCCGCCGACGCCTTGGCCCGTCACCAGCTCGCCGACGATGGCCGCACTTCCGCCACCCCCGCCTCAGCCGGGC
ATCGACTGCCGGGCGGCGGC

Downstream 100 bases:

>100_bases
ACGCCTCTCTGCGCCGAATATCGGTGACCGTGATGGCGTTGATCGTGTTGCTACTGCTCAACGCGACCATGACGCAGGTC
TTCACCGCCGACGGGCTGCG

Product: cell division protein rodA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 469; Mature: 468

Protein sequence:

>469_residues
MTTRLQAPVAVTPPLPTRRNAELLLLCFAAVITFAALLVVQANQDQGVPWDLTSYGLAFLTLFGSAHLAIRRFAPYTDPL
LLPVVALLNGLGLVMIHRLDLVDNEIGEHRHPSANQQMLWTLVGVAAFALVVTFLKDHRQLARYGYICGLAGLVFLAVPA
LLPAALSEQNGAKIWIRLPGFSIQPAEFSKILLLIFFSAVLVAKRGLFTSAGKHLLGMTLPRPRDLAPLLAAWVISVGVM
VFEKDLGASLLLYTSFLVVVYLATQRFSWVVIGLTLFAAGTLVAYFIFEHVRLRVQTWLDPFADPDGTGYQIVQSLFSFA
TGGIFGTGLGNGQPDTVPAASTDFIIAAFGEELGLVGLTAILMLYTIVIIRGLRTAIATRDSFGKLLAAGLSSTLAIQLF
IVVGGVTRLIPLTGLTTPWMSYGGSSLLANYILLAILARISHGARRPLRTRPRNKSPITAAGTEVIERV

Sequences:

>Translated_469_residues
MTTRLQAPVAVTPPLPTRRNAELLLLCFAAVITFAALLVVQANQDQGVPWDLTSYGLAFLTLFGSAHLAIRRFAPYTDPL
LLPVVALLNGLGLVMIHRLDLVDNEIGEHRHPSANQQMLWTLVGVAAFALVVTFLKDHRQLARYGYICGLAGLVFLAVPA
LLPAALSEQNGAKIWIRLPGFSIQPAEFSKILLLIFFSAVLVAKRGLFTSAGKHLLGMTLPRPRDLAPLLAAWVISVGVM
VFEKDLGASLLLYTSFLVVVYLATQRFSWVVIGLTLFAAGTLVAYFIFEHVRLRVQTWLDPFADPDGTGYQIVQSLFSFA
TGGIFGTGLGNGQPDTVPAASTDFIIAAFGEELGLVGLTAILMLYTIVIIRGLRTAIATRDSFGKLLAAGLSSTLAIQLF
IVVGGVTRLIPLTGLTTPWMSYGGSSLLANYILLAILARISHGARRPLRTRPRNKSPITAAGTEVIERV
>Mature_468_residues
TTRLQAPVAVTPPLPTRRNAELLLLCFAAVITFAALLVVQANQDQGVPWDLTSYGLAFLTLFGSAHLAIRRFAPYTDPLL
LPVVALLNGLGLVMIHRLDLVDNEIGEHRHPSANQQMLWTLVGVAAFALVVTFLKDHRQLARYGYICGLAGLVFLAVPAL
LPAALSEQNGAKIWIRLPGFSIQPAEFSKILLLIFFSAVLVAKRGLFTSAGKHLLGMTLPRPRDLAPLLAAWVISVGVMV
FEKDLGASLLLYTSFLVVVYLATQRFSWVVIGLTLFAAGTLVAYFIFEHVRLRVQTWLDPFADPDGTGYQIVQSLFSFAT
GGIFGTGLGNGQPDTVPAASTDFIIAAFGEELGLVGLTAILMLYTIVIIRGLRTAIATRDSFGKLLAAGLSSTLAIQLFI
VVGGVTRLIPLTGLTTPWMSYGGSSLLANYILLAILARISHGARRPLRTRPRNKSPITAAGTEVIERV

Specific function: This is a septum-peptidoglycan biosynthetic protein, involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family

Homologues:

Organism=Escherichia coli, GI1786277, Length=285, Percent_Identity=32.280701754386, Blast_Score=125, Evalue=7e-30,
Organism=Escherichia coli, GI1786853, Length=270, Percent_Identity=35.5555555555556, Blast_Score=102, Evalue=5e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FTSW_MYCBO (P63761)

Other databases:

- EMBL:   BX248334
- RefSeq:   NP_853687.1
- ProteinModelPortal:   P63761
- EnsemblBacteria:   EBMYCT00000014627
- GeneID:   1093760
- GenomeReviews:   BX248333_GR
- KEGG:   mbo:Mb0017c
- GeneTree:   EBGT00050000015955
- HOGENOM:   HBG729614
- OMA:   AAILMLY
- ProtClustDB:   CLSK790195
- BioCyc:   MBOV233413:MB0017C-MONOMER
- InterPro:   IPR001182
- InterPro:   IPR018365

Pfam domain/function: PF01098 FTSW_RODA_SPOVE

EC number: NA

Molecular weight: Translated: 50612; Mature: 50480

Theoretical pI: Translated: 10.12; Mature: 10.12

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x16fe3d38)-; HASH(0x17730eb0)-; HASH(0x1778b7e0)-; HASH(0x1773b640)-; HASH(0x1772e9c8)-; HASH(0x1776c294)-; HASH(0x177bd86c)-; HASH(0x177bea90)-; HASH(0x177beee4)-; HASH(0x177be914)-; HASH(0x177531e4)-; HASH(0x1773b46c)-; HASH(0x17743424)-;

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTRLQAPVAVTPPLPTRRNAELLLLCFAAVITFAALLVVQANQDQGVPWDLTSYGLAFL
CCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
TLFGSAHLAIRRFAPYTDPLLLPVVALLNGLGLVMIHRLDLVDNEIGEHRHPSANQQMLW
HHHCCHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
TLVGVAAFALVVTFLKDHRQLARYGYICGLAGLVFLAVPALLPAALSEQNGAKIWIRLPG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCC
FSIQPAEFSKILLLIFFSAVLVAKRGLFTSAGKHLLGMTLPRPRDLAPLLAAWVISVGVM
CCCCHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHCCCCCCCCCHHHHHHHHHHHHHHH
VFEKDLGASLLLYTSFLVVVYLATQRFSWVVIGLTLFAAGTLVAYFIFEHVRLRVQTWLD
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PFADPDGTGYQIVQSLFSFATGGIFGTGLGNGQPDTVPAASTDFIIAAFGEELGLVGLTA
CCCCCCCCHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHH
ILMLYTIVIIRGLRTAIATRDSFGKLLAAGLSSTLAIQLFIVVGGVTRLIPLTGLTTPWM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
SYGGSSLLANYILLAILARISHGARRPLRTRPRNKSPITAAGTEVIERV
HCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCH
>Mature Secondary Structure 
TTRLQAPVAVTPPLPTRRNAELLLLCFAAVITFAALLVVQANQDQGVPWDLTSYGLAFL
CCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH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HCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12788972