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The map label for this gene is galE1 [C]

Identifier: 148663497

GI number: 148663497

Start: 4081114

End: 4082058

Strand: Reverse

Name: galE1 [C]

Synonym: MRA_3670

Alternate gene names: 148663497

Gene position: 4082058-4081114 (Counterclockwise)

Preceding gene: 148663502

Following gene: 148663492

Centisome position: 92.35

GC content: 64.87

Gene sequence:

>945_bases
GTGCGCGCACTGGTCACTGGGGCGGCCGGATTCATCGGCTCGACGTTAGTCGACCGGTTGCTGGCAGATGGTCATTCGGT
GGTGGGATTGGACAACTTCGCGACCGGCCGGGCGACCAACCTCGAGCATCTGGCCGACAACTCCGCACACGTCTTCGTCG
AAGCCGACATTGTGACCGCCGATCTACACGCCATCCTCGAGCAGCACCGGCCCGAGGTGGTATTTCACCTGGCGGCCCAG
ATCGATGTCCGCCGTTCGGTGGCTGACCCGCAATTCGACGCCGCGGTCAATGTCATCGGCACGGTGCGCCTAGCCGAGGC
CGCGCGGCAGACCGGTGTCCGCAAGATCGTGCACACCTCCTCGGGAGGATCGATCTATGGCACCCCGCCGGAGTATCCAA
CCCCTGAGACAGCGCCCACCGATCCGGCCTCGCCGTATGCCGCGGGCAAAGTGGCCGGCGAAATCTACCTGAACACCTTT
CGACATCTCTACGGCCTGGACTGCTCGCATATCGCACCGGCTAACGTCTACGGTCCTCGCCAGGACCCACACGGTGAAGC
GGGTGTGGTAGCGATCTTCGCGCAGGCGCTGCTCTCGGGCAAACCCACCAGGGTGTTCGGCGACGGCACCAATACGCGCG
ACTATGTGTTTGTCGACGACGTGGTCGACGCGTTTGTCCGGGTGTCCGCGGACGTCGGCGGTGGGCTGCGCTTCAACATC
GGCACCGGTAAGGAAACGTCGGACCGCCAACTGCATTCGGCGGTGGCCGCGGCTGTCGGCGGGCCCGACGACCCTGAGTT
CCACCCGCCGCGGCTAGGCGATCTTAAGCGGTCCTGCCTTGACATCGGCTTAGCCGAACGGGTTTTGGGCTGGCGTCCGC
AGATCGAGTTGGCCGACGGCGTGCGTCGCACGGTCGAGTACTTCCGGCACAAGCACACTGATTGA

Upstream 100 bases:

>100_bases
CACCACGCGAACCACCAGCTGCACCGTGATCAGCAATACGGCGACCAGGGCGACCCGAGGCATACGGGGCGCTGGCATGG
GCCGCCGGTATGGTGGGCCG

Downstream 100 bases:

>100_bases
TCAGAGCCTGACCGAAGTCTGCAGACGGTCCGCTACGGCGTCCAAGAACGGATGCCGGTCGGCGTCGAGATAGTCGGCCG
GCGGTCGCCAGTCGATTCGG

Product: NAD-dependent epimerase/dehydratase family protein

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 314; Mature: 314

Protein sequence:

>314_residues
MRALVTGAAGFIGSTLVDRLLADGHSVVGLDNFATGRATNLEHLADNSAHVFVEADIVTADLHAILEQHRPEVVFHLAAQ
IDVRRSVADPQFDAAVNVIGTVRLAEAARQTGVRKIVHTSSGGSIYGTPPEYPTPETAPTDPASPYAAGKVAGEIYLNTF
RHLYGLDCSHIAPANVYGPRQDPHGEAGVVAIFAQALLSGKPTRVFGDGTNTRDYVFVDDVVDAFVRVSADVGGGLRFNI
GTGKETSDRQLHSAVAAAVGGPDDPEFHPPRLGDLKRSCLDIGLAERVLGWRPQIELADGVRRTVEYFRHKHTD

Sequences:

>Translated_314_residues
MRALVTGAAGFIGSTLVDRLLADGHSVVGLDNFATGRATNLEHLADNSAHVFVEADIVTADLHAILEQHRPEVVFHLAAQ
IDVRRSVADPQFDAAVNVIGTVRLAEAARQTGVRKIVHTSSGGSIYGTPPEYPTPETAPTDPASPYAAGKVAGEIYLNTF
RHLYGLDCSHIAPANVYGPRQDPHGEAGVVAIFAQALLSGKPTRVFGDGTNTRDYVFVDDVVDAFVRVSADVGGGLRFNI
GTGKETSDRQLHSAVAAAVGGPDDPEFHPPRLGDLKRSCLDIGLAERVLGWRPQIELADGVRRTVEYFRHKHTD
>Mature_314_residues
MRALVTGAAGFIGSTLVDRLLADGHSVVGLDNFATGRATNLEHLADNSAHVFVEADIVTADLHAILEQHRPEVVFHLAAQ
IDVRRSVADPQFDAAVNVIGTVRLAEAARQTGVRKIVHTSSGGSIYGTPPEYPTPETAPTDPASPYAAGKVAGEIYLNTF
RHLYGLDCSHIAPANVYGPRQDPHGEAGVVAIFAQALLSGKPTRVFGDGTNTRDYVFVDDVVDAFVRVSADVGGGLRFNI
GTGKETSDRQLHSAVAAAVGGPDDPEFHPPRLGDLKRSCLDIGLAERVLGWRPQIELADGVRRTVEYFRHKHTD

Specific function: DTDP-L-RHAMNOSE BIOSYNTHESIS WITHIN THE O ANTIGEN BIOSYNTHESIS PATHWAY OF LIPOPOLYSACCHARIDE BIOSYNTHESIS. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI7657641, Length=318, Percent_Identity=29.2452830188679, Blast_Score=142, Evalue=4e-34,
Organism=Homo sapiens, GI42516563, Length=316, Percent_Identity=29.1139240506329, Blast_Score=141, Evalue=7e-34,
Organism=Homo sapiens, GI56237023, Length=328, Percent_Identity=28.3536585365854, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI56118217, Length=328, Percent_Identity=28.3536585365854, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI189083684, Length=328, Percent_Identity=28.3536585365854, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI4504031, Length=342, Percent_Identity=26.6081871345029, Blast_Score=84, Evalue=1e-16,
Organism=Escherichia coli, GI1788353, Length=339, Percent_Identity=31.2684365781711, Blast_Score=134, Evalue=6e-33,
Organism=Escherichia coli, GI48994969, Length=335, Percent_Identity=29.2537313432836, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1786974, Length=337, Percent_Identity=32.0474777448071, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1788366, Length=356, Percent_Identity=28.3707865168539, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI1788365, Length=234, Percent_Identity=26.9230769230769, Blast_Score=71, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17539532, Length=325, Percent_Identity=30.1538461538462, Blast_Score=140, Evalue=6e-34,
Organism=Caenorhabditis elegans, GI17568069, Length=328, Percent_Identity=29.2682926829268, Blast_Score=129, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI71982035, Length=332, Percent_Identity=30.421686746988, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI71982038, Length=334, Percent_Identity=30.2395209580838, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI115532424, Length=329, Percent_Identity=27.0516717325228, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI133901790, Length=352, Percent_Identity=26.1363636363636, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17507723, Length=346, Percent_Identity=26.5895953757225, Blast_Score=88, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI133901788, Length=352, Percent_Identity=26.1363636363636, Blast_Score=88, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17539422, Length=352, Percent_Identity=26.1363636363636, Blast_Score=88, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17539424, Length=352, Percent_Identity=26.1363636363636, Blast_Score=88, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI133901786, Length=352, Percent_Identity=26.1363636363636, Blast_Score=88, Evalue=6e-18,
Organism=Saccharomyces cerevisiae, GI6319493, Length=332, Percent_Identity=26.5060240963855, Blast_Score=90, Evalue=6e-19,
Organism=Drosophila melanogaster, GI21356223, Length=315, Percent_Identity=29.5238095238095, Blast_Score=137, Evalue=9e-33,
Organism=Drosophila melanogaster, GI19923002, Length=322, Percent_Identity=27.9503105590062, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24158427, Length=348, Percent_Identity=26.7241379310345, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 33582; Mature: 33582

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRALVTGAAGFIGSTLVDRLLADGHSVVGLDNFATGRATNLEHLADNSAHVFVEADIVTA
CCCEECCHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCHHHHCCCCCEEEEEECCHHH
DLHAILEQHRPEVVFHLAAQIDVRRSVADPQFDAAVNVIGTVRLAEAARQTGVRKIVHTS
HHHHHHHHCCCCEEEHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEC
SGGSIYGTPPEYPTPETAPTDPASPYAAGKVAGEIYLNTFRHLYGLDCSHIAPANVYGPR
CCCEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
QDPHGEAGVVAIFAQALLSGKPTRVFGDGTNTRDYVFVDDVVDAFVRVSADVGGGLRFNI
CCCCCCHHHHHHHHHHHHCCCCCEEECCCCCCCCEEEHHHHHHHHHHHHCCCCCCEEEEE
GTGKETSDRQLHSAVAAAVGGPDDPEFHPPRLGDLKRSCLDIGLAERVLGWRPQIELADG
CCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
VRRTVEYFRHKHTD
HHHHHHHHHHCCCC
>Mature Secondary Structure
MRALVTGAAGFIGSTLVDRLLADGHSVVGLDNFATGRATNLEHLADNSAHVFVEADIVTA
CCCEECCHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCHHHHCCCCCEEEEEECCHHH
DLHAILEQHRPEVVFHLAAQIDVRRSVADPQFDAAVNVIGTVRLAEAARQTGVRKIVHTS
HHHHHHHHCCCCEEEHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEC
SGGSIYGTPPEYPTPETAPTDPASPYAAGKVAGEIYLNTFRHLYGLDCSHIAPANVYGPR
CCCEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
QDPHGEAGVVAIFAQALLSGKPTRVFGDGTNTRDYVFVDDVVDAFVRVSADVGGGLRFNI
CCCCCCHHHHHHHHHHHHCCCCCEEECCCCCCCCEEEHHHHHHHHHHHHCCCCCCEEEEE
GTGKETSDRQLHSAVAAAVGGPDDPEFHPPRLGDLKRSCLDIGLAERVLGWRPQIELADG
CCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
VRRTVEYFRHKHTD
HHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]