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The map label for this gene is ppe65

Identifier: 148663484

GI number: 148663484

Start: 4069095

End: 4070336

Strand: Reverse

Name: ppe65

Synonym: MRA_3657

Alternate gene names: 148663484

Gene position: 4070336-4069095 (Counterclockwise)

Preceding gene: 148663485

Following gene: 148663483

Centisome position: 92.09

GC content: 68.04

Gene sequence:

>1242_bases
ATGCTGGACTTTGCTCAGTTACCGCCGGAGGTCAACTCCGCGCTGATGTACGCCGGACCCGGTTCGGGACCGATGCTGGC
TGCCGCGGCGGCCTGGGAGGCGCTGGCCGCCGAGTTGCAAACCACGGCGTCCACCTACGACGCTCTGATCACTGGCCTGG
CCGACGGGCCATGGCAGGGGTCCTCCGCGGCGTCCATGGTGGCTGCCGCCACGCCCCAGGTGGCGTGGTTGAGGAGCACC
GCCGGGCAGGCCGAGCAAGCCGGCAGCCAAGCGGTGGCAGCGGCGAGTGCTTATGAGGCGGCGTTTTTCGCGACCGTGCC
GCCCCCGGAGATCGCGGCCAACAGGGCGTTGTTGATGGCGTTGCTGGCGACGAACTTCCTTGGCCAGAACACGGCGGCGA
TCGCGGCCACCGAGGCGCAATACGCCGAGATGTGGGCCCAGGATGCGGCCGCGATGTACGGCTATGCTGGCGCGTCGGCG
GCGGCGACGCAGTTGTCGCCATTCAATCCGGCGGCGCAGACCATCAACCCGGCCGGGCTGGCCAGCCAGGCCGCATCTGT
CGGACAAGCTGTCAGCGGGGCCGCAAATGCGCAAGCACTCACCGACATTCCTAAAGCGTTGTTTGGGCTTAGCGGAATCT
TCACCAATGAACCGCCTTGGCTCACCGACCTTGGCAAGGCGCTCGGTTTGACCGGGCACACCTGGTCCTCGGACGGTAGC
GGGCTCATCGTGGGCGGAGTGCTTGGCGACTTTGTGCAGGGTGTGACCGGGTCGGCCGAACTTGATGCCAGCGTGGCCAT
GGACACGTTCGGCAAATGGGTCTCGCCCGCTCGGCTCATGGTCACCCAATTCAAGGACTACTTTGGCCTGGCGCACGACC
TGCCGAAGTGGGCGAGTGAAGGCGCCAAAGCCGCCGGTGAGGCCGCCAAGGCGTTGCCGGCCGCCGTTCCGGCCATTCCG
AGTGCTGGCCTGAGCGGCGTTGCGGGCGCCGTCGGTCAGGCGGCGTCGGTCGGGGGATTGAAGGTTCCGGCCGTTTGGAC
CGCCACGACCCCGGCGGCGAGCCCCGCGGTGCTGGCGGCGTCCAACGGCCTCGGAGCCGCGGCCGCCGCTGAAGGTTCGA
CACACGCGTTTGGCGGGATGCCGCTCATGGGTAGCGGTGCCGGACGTGCGTTTAACAACTTCGCTGCCCCTCGATACGGA
TTCAAGCCGACCGTGATCGCCCAACCGCCGGCTGGCGGATGA

Upstream 100 bases:

>100_bases
GGCGGTCCAGGAGCAGTTGGCGACCACGCTGGGCATCAGCGCCGGTTCATATGCGGCCACCGAGGCTGCCAACGCCGCCA
CGATCGCTTAGGAGAGGCCG

Downstream 100 bases:

>100_bases
CCAACTACGTTCGTTGATCGAGGATCGAATTCGACGATTCAAAGGGAGGAATTCATATGACCTCGCGTTTTATGACGGAT
CCGCACGCGATGCGGGACAT

Product: PPE family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 413; Mature: 413

Protein sequence:

>413_residues
MLDFAQLPPEVNSALMYAGPGSGPMLAAAAAWEALAAELQTTASTYDALITGLADGPWQGSSAASMVAAATPQVAWLRST
AGQAEQAGSQAVAAASAYEAAFFATVPPPEIAANRALLMALLATNFLGQNTAAIAATEAQYAEMWAQDAAAMYGYAGASA
AATQLSPFNPAAQTINPAGLASQAASVGQAVSGAANAQALTDIPKALFGLSGIFTNEPPWLTDLGKALGLTGHTWSSDGS
GLIVGGVLGDFVQGVTGSAELDASVAMDTFGKWVSPARLMVTQFKDYFGLAHDLPKWASEGAKAAGEAAKALPAAVPAIP
SAGLSGVAGAVGQAASVGGLKVPAVWTATTPAASPAVLAASNGLGAAAAAEGSTHAFGGMPLMGSGAGRAFNNFAAPRYG
FKPTVIAQPPAGG

Sequences:

>Translated_413_residues
MLDFAQLPPEVNSALMYAGPGSGPMLAAAAAWEALAAELQTTASTYDALITGLADGPWQGSSAASMVAAATPQVAWLRST
AGQAEQAGSQAVAAASAYEAAFFATVPPPEIAANRALLMALLATNFLGQNTAAIAATEAQYAEMWAQDAAAMYGYAGASA
AATQLSPFNPAAQTINPAGLASQAASVGQAVSGAANAQALTDIPKALFGLSGIFTNEPPWLTDLGKALGLTGHTWSSDGS
GLIVGGVLGDFVQGVTGSAELDASVAMDTFGKWVSPARLMVTQFKDYFGLAHDLPKWASEGAKAAGEAAKALPAAVPAIP
SAGLSGVAGAVGQAASVGGLKVPAVWTATTPAASPAVLAASNGLGAAAAAEGSTHAFGGMPLMGSGAGRAFNNFAAPRYG
FKPTVIAQPPAGG
>Mature_413_residues
MLDFAQLPPEVNSALMYAGPGSGPMLAAAAAWEALAAELQTTASTYDALITGLADGPWQGSSAASMVAAATPQVAWLRST
AGQAEQAGSQAVAAASAYEAAFFATVPPPEIAANRALLMALLATNFLGQNTAAIAATEAQYAEMWAQDAAAMYGYAGASA
AATQLSPFNPAAQTINPAGLASQAASVGQAVSGAANAQALTDIPKALFGLSGIFTNEPPWLTDLGKALGLTGHTWSSDGS
GLIVGGVLGDFVQGVTGSAELDASVAMDTFGKWVSPARLMVTQFKDYFGLAHDLPKWASEGAKAAGEAAKALPAAVPAIP
SAGLSGVAGAVGQAASVGGLKVPAVWTATTPAASPAVLAASNGLGAAAAAEGSTHAFGGMPLMGSGAGRAFNNFAAPRYG
FKPTVIAQPPAGG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mycobacterial PPE family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PPE65_MYCTU (Q7D569)

Other databases:

- EMBL:   BX842583
- EMBL:   AE000516
- PIR:   F70560
- RefSeq:   NP_338270.1
- RefSeq:   YP_177998.1
- HSSP:   Q79FE1
- ProteinModelPortal:   Q7D569
- SMR:   Q7D569
- EnsemblBacteria:   EBMYCT00000001026
- EnsemblBacteria:   EBMYCT00000070316
- GeneID:   885097
- GeneID:   922770
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT3723
- KEGG:   mtu:Rv3621c
- TIGR:   MT3723
- TubercuList:   Rv3621c
- GeneTree:   EBGT00050000014887
- HOGENOM:   HBG572308
- OMA:   AVSAYET
- ProtClustDB:   CLSK800008
- InterPro:   IPR022171
- InterPro:   IPR000030

Pfam domain/function: PF12484 PE_PPE_C; PF00823 PPE

EC number: NA

Molecular weight: Translated: 40680; Mature: 40680

Theoretical pI: Translated: 4.35; Mature: 4.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDFAQLPPEVNSALMYAGPGSGPMLAAAAAWEALAAELQTTASTYDALITGLADGPWQG
CCCCHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
SSAASMVAAATPQVAWLRSTAGQAEQAGSQAVAAASAYEAAFFATVPPPEIAANRALLMA
CHHHHHHHHCCCCHHHHHHHCCHHHHHCCHHHHHHHHHHHEEEECCCCHHHHHHHHHHHH
LLATNFLGQNTAAIAATEAQYAEMWAQDAAAMYGYAGASAAATQLSPFNPAAQTINPAGL
HHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCHHHCCCCHHH
ASQAASVGQAVSGAANAQALTDIPKALFGLSGIFTNEPPWLTDLGKALGLTGHTWSSDGS
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCC
GLIVGGVLGDFVQGVTGSAELDASVAMDTFGKWVSPARLMVTQFKDYFGLAHDLPKWASE
CEEEHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
GAKAAGEAAKALPAAVPAIPSAGLSGVAGAVGQAASVGGLKVPAVWTATTPAASPAVLAA
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCHHCCCCEECCEEEECCCCCCCCEEEEE
SNGLGAAAAAEGSTHAFGGMPLMGSGAGRAFNNFAAPRYGFKPTVIAQPPAGG
CCCCCCHHHCCCCCCCCCCCCEECCCCCCHHHHCCCCCCCCCCCEEECCCCCC
>Mature Secondary Structure
MLDFAQLPPEVNSALMYAGPGSGPMLAAAAAWEALAAELQTTASTYDALITGLADGPWQG
CCCCHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
SSAASMVAAATPQVAWLRSTAGQAEQAGSQAVAAASAYEAAFFATVPPPEIAANRALLMA
CHHHHHHHHCCCCHHHHHHHCCHHHHHCCHHHHHHHHHHHEEEECCCCHHHHHHHHHHHH
LLATNFLGQNTAAIAATEAQYAEMWAQDAAAMYGYAGASAAATQLSPFNPAAQTINPAGL
HHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCHHHCCCCHHH
ASQAASVGQAVSGAANAQALTDIPKALFGLSGIFTNEPPWLTDLGKALGLTGHTWSSDGS
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCC
GLIVGGVLGDFVQGVTGSAELDASVAMDTFGKWVSPARLMVTQFKDYFGLAHDLPKWASE
CEEEHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
GAKAAGEAAKALPAAVPAIPSAGLSGVAGAVGQAASVGGLKVPAVWTATTPAASPAVLAA
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCHHCCCCEECCEEEECCCCCCCCEEEEE
SNGLGAAAAAEGSTHAFGGMPLMGSGAGRAFNNFAAPRYGFKPTVIAQPPAGG
CCCCCCHHHCCCCCCCCCCCCEECCCCCCHHHHCCCCCCCCCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036