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The map label for this gene is yeaZ [C]

Identifier: 148663285

GI number: 148663285

Start: 3847737

End: 3848372

Strand: Reverse

Name: yeaZ [C]

Synonym: MRA_3461

Alternate gene names: 148663285

Gene position: 3848372-3847737 (Counterclockwise)

Preceding gene: 148663286

Following gene: 148663284

Centisome position: 87.07

GC content: 70.13

Gene sequence:

>636_bases
ATGAGCCGCGTGCAAATAAGCACCGTCTTGGCCATCGACACCGCTACACCGGCGGTCACGGCGGGTATCGTGCGGCGTCA
TGATCTGGTTGTGCTGGGCGAGAGGGTCACCGTCGACGCCCGAGCGCACGCGGAACGGCTGACTCCCAACGTGCTGGCTG
CGCTTGCCGATGCCGCGCTCACAATGGCCGACCTGGACGCCGTCGTGGTGGGCTGCGGTCCGGGCCCGTTCACCGGGCTG
CGCGCAGGCATGGCCTCCGCCGCCGCGTACGGGCACGCACTGGGCATCCCGGTGTATGGCGTGTGCAGCCTGGACGCCAT
CGGCGGGCAAACCATCGGTGACACGCTGGTGGTCACCGATGCACGCCGGCGTGAGGTCTACTGGGCACGCTACTGCGACG
GGATTCGTACGGTCGGACCAGCCGTTAATGCCGCGGCCGACGTCGATCCCGGCCCGGCATTGGCGGTCGCCGGTGCGCCG
GAGCACGCGGCGCTGTTCGCGCTCCCCTGCGTTGAGCCCAGCCGCCCGTCGCCGGCGGGTCTGGTAGCCGCGGTGAACTG
GGCCGACAAGCCGGCGCCGTTAGTGCCGCTGTATCTTCGCCGGCCGGATGCCAAGCCGCTGGCGGTTTGCACGTGA

Upstream 100 bases:

>100_bases
AGGGCCTGGCCGAGCGGCTCTCGCAGCGCCACCTCGACGTCCGCCTGGAGCGGGTTAGCCACTCCGACACCAGGATCGCG
ACTTGGTCGTGGGGCCGGTC

Downstream 100 bases:

>100_bases
CGGCCGACACCGAGCCCGTCACCATCGGCGCGCTGACGCGCGCGGACGCCCAGCGGTGCGCCGAGCTGGAGGCCCAGCTG
TTCGTCGGTGACGATCCCTG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 211; Mature: 210

Protein sequence:

>211_residues
MSRVQISTVLAIDTATPAVTAGIVRRHDLVVLGERVTVDARAHAERLTPNVLAALADAALTMADLDAVVVGCGPGPFTGL
RAGMASAAAYGHALGIPVYGVCSLDAIGGQTIGDTLVVTDARRREVYWARYCDGIRTVGPAVNAAADVDPGPALAVAGAP
EHAALFALPCVEPSRPSPAGLVAAVNWADKPAPLVPLYLRRPDAKPLAVCT

Sequences:

>Translated_211_residues
MSRVQISTVLAIDTATPAVTAGIVRRHDLVVLGERVTVDARAHAERLTPNVLAALADAALTMADLDAVVVGCGPGPFTGL
RAGMASAAAYGHALGIPVYGVCSLDAIGGQTIGDTLVVTDARRREVYWARYCDGIRTVGPAVNAAADVDPGPALAVAGAP
EHAALFALPCVEPSRPSPAGLVAAVNWADKPAPLVPLYLRRPDAKPLAVCT
>Mature_210_residues
SRVQISTVLAIDTATPAVTAGIVRRHDLVVLGERVTVDARAHAERLTPNVLAALADAALTMADLDAVVVGCGPGPFTGLR
AGMASAAAYGHALGIPVYGVCSLDAIGGQTIGDTLVVTDARRREVYWARYCDGIRTVGPAVNAAADVDPGPALAVAGAPE
HAALFALPCVEPSRPSPAGLVAAVNWADKPAPLVPLYLRRPDAKPLAVCT

Specific function: Unknown

COG id: COG1214

COG function: function code O; Inactive homolog of metal-dependent proteases, putative molecular chaperone

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To M.leprae ML0378

Homologues:

Organism=Escherichia coli, GI1788109, Length=134, Percent_Identity=35.0746268656716, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y3421_MYCTU (P65083)

Other databases:

- EMBL:   BX842583
- EMBL:   AE000516
- PIR:   B70738
- RefSeq:   NP_217938.1
- RefSeq:   NP_338054.1
- ProteinModelPortal:   P65083
- SMR:   P65083
- EnsemblBacteria:   EBMYCT00000000141
- EnsemblBacteria:   EBMYCT00000072971
- GeneID:   887532
- GeneID:   923468
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT3530
- KEGG:   mtu:Rv3421c
- TIGR:   MT3530
- TubercuList:   Rv3421c
- GeneTree:   EBGT00050000015588
- HOGENOM:   HBG691477
- OMA:   LYLRGPD
- ProtClustDB:   CLSK792482
- GO:   GO:0006508
- InterPro:   IPR022496
- InterPro:   IPR000905
- TIGRFAMs:   TIGR03725

Pfam domain/function: PF00814 Peptidase_M22

EC number: NA

Molecular weight: Translated: 21572; Mature: 21441

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRVQISTVLAIDTATPAVTAGIVRRHDLVVLGERVTVDARAHAERLTPNVLAALADAAL
CCCEEEEEEEEEECCCCHHHHHHHHHCCEEEECCEEEEEHHHHHHHCCHHHHHHHHHHHH
TMADLDAVVVGCGPGPFTGLRAGMASAAAYGHALGIPVYGVCSLDAIGGQTIGDTLVVTD
HHCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCEEEEEC
ARRREVYWARYCDGIRTVGPAVNAAADVDPGPALAVAGAPEHAALFALPCVEPSRPSPAG
CCHHHHHHHHHCCCHHHCCCCCCCCCCCCCCCEEEEECCCCCCEEEEEECCCCCCCCCCC
LVAAVNWADKPAPLVPLYLRRPDAKPLAVCT
EEEEEECCCCCCCEEEEEEECCCCCCEEEEC
>Mature Secondary Structure 
SRVQISTVLAIDTATPAVTAGIVRRHDLVVLGERVTVDARAHAERLTPNVLAALADAAL
CCEEEEEEEEEECCCCHHHHHHHHHCCEEEECCEEEEEHHHHHHHCCHHHHHHHHHHHH
TMADLDAVVVGCGPGPFTGLRAGMASAAAYGHALGIPVYGVCSLDAIGGQTIGDTLVVTD
HHCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCEEEEEC
ARRREVYWARYCDGIRTVGPAVNAAADVDPGPALAVAGAPEHAALFALPCVEPSRPSPAG
CCHHHHHHHHHCCCHHHCCCCCCCCCCCCCCCEEEEECCCCCCEEEEEECCCCCCCCCCC
LVAAVNWADKPAPLVPLYLRRPDAKPLAVCT
EEEEEECCCCCCCEEEEEEECCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036