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The map label for this gene is glpD2

Identifier: 148663165

GI number: 148663165

Start: 3698468

End: 3700225

Strand: Reverse

Name: glpD2

Synonym: MRA_3343

Alternate gene names: 148663165

Gene position: 3700225-3698468 (Counterclockwise)

Preceding gene: 148663166

Following gene: 148663164

Centisome position: 83.72

GC content: 66.84

Gene sequence:

>1758_bases
GTGAGCAACCCAATCCAGGCACCGGACGGCGGGCAGGGGTGGCCCGCCGCGGCGCTGGGACCTGCACAGCGCGCGGTCGC
CTGGAAGCGACTCGGAACCGAGCAATTCGACGTCGTGGTGATCGGCGGCGGAGTAGTGGGCTCCGGATGCGCTTTGGATG
CTGCCACCCGTGGGCTCAAGGTGGCGTTGGTCGAGGCGCGGGACTTGGCCTCCGGCACGTCGAGCCGCTCCTCGAAGATG
TTCCACGGCGGGCTGCGCTACCTCGAGCAACTGGAGTTCGGGCTGGTGCGTGAGGCGCTCTATGAACGTGAACTGTCGCT
GACCACGCTGGCACCGCATTTGGTCAAGCCGCTGCCGTTTTTGTTCCCGCTGACCAAACGCTGGTGGGAGCGTCCCTACA
TCGCCGCGGGTATCTTTCTTTACGACCGGCTGGGTGGCGCGAAATCGGTTCCGGCGCAACGGCATTTTACTCGCGCCGGT
GCGCTGCGACTGAGCCCCGGCTTGAAGCGCAGCTCGCTGATCGGTGGTATCCGTTACTACGACACCGTCGTCGACGACGC
CCGGCACACCATGACGGTCGCGCGCACCGCGGCGCATTACGGCGCGGTTGTCCGCTGCTCCACCCAGGTAGTGGCCTTGT
TGCGAGAGGGTGACCGGGTGATCGGCGTGGGCGTCCGCGACTCCGAGAACGGCGCGGTTGCCGAGGTTCGCGGCCACGTC
GTGGTCAACGCGACCGGGGTCTGGACCGATGAGATTCAAGCGTTGTCCAAACAGCGCGGGCGCTTCCAGGTGCGCGCATC
CAAGGGCGTGCATGTGGTGGTGCCGCGGGACCGGATTGTCAGTGACGTCGCGATGATCCTGCGCACGGAGAAGTCGGTGA
TGTTTGTCATTCCGTGGGGAAGTCACTGGATCATCGGAACCACCGATACCGACTGGAACCTCGACCTGGCGCACCCCGCG
GCCACCAAGGCCGACATCGACTACATCCTGGGCACTGTCAACGCCGTGTTGGCGACCCCGTTGACGCACGCCGACATTGA
CGGAGTGTACGCCGGGCTGCGGCCGCTGCTTGCCGGGGAAAGCGACGACACCTCCAAGCTGTCCCGGGAACACGCCGTGG
CTGTGCCGGCGGCGGGCCTGGTGGCCATCGCCGGTGGCAAGTACACCACCTACCGAGTAATGGCGGCCGACGCGATCGAC
GCTGCTGTGCAGTTCATCCCCGCCCGCGTTGCGCCGTCGATCACCGAGAAGGTCAGCCTGCTGGGCGCCGACGGTTACTT
TGCACTGGTCAATCAGGCCGAACACGTCGGCGCGCTGCAGGGCCTGCACCCGTACCGGGTGCGCCATCTGCTGGACCGCT
ATGGTTCGCTGATCAGCGACGTTCTAGCGATGGCGGCCTCCGATCCCAGCCTGTTGAGCCCGATAACGGAGGCACCGGGC
TATTTGAAGGTGGAAGCCGCTTACGCCGCCGCCGCCGAGGGCGCCCTGCATCTCGAGGACATCCTGGCCCGTCGGATGCG
GATTTCCATCGAATACCCGCACCGGGGCGTCGACTGCGCCCGGGAGGTGGCCGAGGTGGTCGCGCCCGTGCTCGGGTGGA
CCGCCGCAGACATCGACCGCGAGGTCGCGAACTATATGGCGCGCGTGGAGGCCGAGGTGCTCTCCCAGGCCCAGCCCGAC
GACGTTTCGGCGGACATGTTGCGGGCCAGCGCACCCGAGGCGCGTGCCGAGATCCTCGAGCCGGTGCCTTTGGATTGA

Upstream 100 bases:

>100_bases
CGCACGACGATCTGGACTGCACGGCAGCTCAAGACGCGGCTGAACAACTAGCCTTGGTGCCACACCACCTACCGACGAGT
AACTGACAGGAGCCGGTTTC

Downstream 100 bases:

>100_bases
AGGCTACGCCAAGCGGGTATGTCGCGCGGTGCCGCCATGGTCGATGATGGCGGTGTGGATCCGCGGCAGCACCACACGAC
GACTCAGGGTCAGAGAGGCG

Product: glycerol-3-phosphate dehydrogenase Glpd2

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 585; Mature: 584

Protein sequence:

>585_residues
MSNPIQAPDGGQGWPAAALGPAQRAVAWKRLGTEQFDVVVIGGGVVGSGCALDAATRGLKVALVEARDLASGTSSRSSKM
FHGGLRYLEQLEFGLVREALYERELSLTTLAPHLVKPLPFLFPLTKRWWERPYIAAGIFLYDRLGGAKSVPAQRHFTRAG
ALRLSPGLKRSSLIGGIRYYDTVVDDARHTMTVARTAAHYGAVVRCSTQVVALLREGDRVIGVGVRDSENGAVAEVRGHV
VVNATGVWTDEIQALSKQRGRFQVRASKGVHVVVPRDRIVSDVAMILRTEKSVMFVIPWGSHWIIGTTDTDWNLDLAHPA
ATKADIDYILGTVNAVLATPLTHADIDGVYAGLRPLLAGESDDTSKLSREHAVAVPAAGLVAIAGGKYTTYRVMAADAID
AAVQFIPARVAPSITEKVSLLGADGYFALVNQAEHVGALQGLHPYRVRHLLDRYGSLISDVLAMAASDPSLLSPITEAPG
YLKVEAAYAAAAEGALHLEDILARRMRISIEYPHRGVDCAREVAEVVAPVLGWTAADIDREVANYMARVEAEVLSQAQPD
DVSADMLRASAPEARAEILEPVPLD

Sequences:

>Translated_585_residues
MSNPIQAPDGGQGWPAAALGPAQRAVAWKRLGTEQFDVVVIGGGVVGSGCALDAATRGLKVALVEARDLASGTSSRSSKM
FHGGLRYLEQLEFGLVREALYERELSLTTLAPHLVKPLPFLFPLTKRWWERPYIAAGIFLYDRLGGAKSVPAQRHFTRAG
ALRLSPGLKRSSLIGGIRYYDTVVDDARHTMTVARTAAHYGAVVRCSTQVVALLREGDRVIGVGVRDSENGAVAEVRGHV
VVNATGVWTDEIQALSKQRGRFQVRASKGVHVVVPRDRIVSDVAMILRTEKSVMFVIPWGSHWIIGTTDTDWNLDLAHPA
ATKADIDYILGTVNAVLATPLTHADIDGVYAGLRPLLAGESDDTSKLSREHAVAVPAAGLVAIAGGKYTTYRVMAADAID
AAVQFIPARVAPSITEKVSLLGADGYFALVNQAEHVGALQGLHPYRVRHLLDRYGSLISDVLAMAASDPSLLSPITEAPG
YLKVEAAYAAAAEGALHLEDILARRMRISIEYPHRGVDCAREVAEVVAPVLGWTAADIDREVANYMARVEAEVLSQAQPD
DVSADMLRASAPEARAEILEPVPLD
>Mature_584_residues
SNPIQAPDGGQGWPAAALGPAQRAVAWKRLGTEQFDVVVIGGGVVGSGCALDAATRGLKVALVEARDLASGTSSRSSKMF
HGGLRYLEQLEFGLVREALYERELSLTTLAPHLVKPLPFLFPLTKRWWERPYIAAGIFLYDRLGGAKSVPAQRHFTRAGA
LRLSPGLKRSSLIGGIRYYDTVVDDARHTMTVARTAAHYGAVVRCSTQVVALLREGDRVIGVGVRDSENGAVAEVRGHVV
VNATGVWTDEIQALSKQRGRFQVRASKGVHVVVPRDRIVSDVAMILRTEKSVMFVIPWGSHWIIGTTDTDWNLDLAHPAA
TKADIDYILGTVNAVLATPLTHADIDGVYAGLRPLLAGESDDTSKLSREHAVAVPAAGLVAIAGGKYTTYRVMAADAIDA
AVQFIPARVAPSITEKVSLLGADGYFALVNQAEHVGALQGLHPYRVRHLLDRYGSLISDVLAMAASDPSLLSPITEAPGY
LKVEAAYAAAAEGALHLEDILARRMRISIEYPHRGVDCAREVAEVVAPVLGWTAADIDREVANYMARVEAEVLSQAQPDD
VSADMLRASAPEARAEILEPVPLD

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Molecular Oxygen Or Nitrate As Electron Acceptor. [C]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family

Homologues:

Organism=Homo sapiens, GI285002233, Length=541, Percent_Identity=35.4898336414048, Blast_Score=296, Evalue=3e-80,
Organism=Homo sapiens, GI285002231, Length=541, Percent_Identity=35.4898336414048, Blast_Score=296, Evalue=3e-80,
Organism=Escherichia coli, GI2367226, Length=472, Percent_Identity=32.2033898305085, Blast_Score=191, Evalue=1e-49,
Organism=Escherichia coli, GI1788574, Length=381, Percent_Identity=30.1837270341207, Blast_Score=117, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17509253, Length=561, Percent_Identity=33.6898395721925, Blast_Score=250, Evalue=1e-66,
Organism=Caenorhabditis elegans, GI115534726, Length=527, Percent_Identity=32.258064516129, Blast_Score=230, Evalue=2e-60,
Organism=Saccharomyces cerevisiae, GI6322036, Length=495, Percent_Identity=34.9494949494949, Blast_Score=220, Evalue=5e-58,
Organism=Drosophila melanogaster, GI161077125, Length=540, Percent_Identity=34.8148148148148, Blast_Score=263, Evalue=2e-70,
Organism=Drosophila melanogaster, GI24653942, Length=540, Percent_Identity=34.8148148148148, Blast_Score=263, Evalue=2e-70,
Organism=Drosophila melanogaster, GI24653944, Length=540, Percent_Identity=34.8148148148148, Blast_Score=263, Evalue=2e-70,
Organism=Drosophila melanogaster, GI20130025, Length=540, Percent_Identity=34.8148148148148, Blast_Score=263, Evalue=2e-70,
Organism=Drosophila melanogaster, GI24586295, Length=584, Percent_Identity=30.6506849315068, Blast_Score=219, Evalue=4e-57,
Organism=Drosophila melanogaster, GI19921278, Length=517, Percent_Identity=29.4003868471954, Blast_Score=170, Evalue=2e-42,
Organism=Drosophila melanogaster, GI45550977, Length=366, Percent_Identity=25.9562841530055, Blast_Score=111, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLPD2_MYCBO (P64185)

Other databases:

- EMBL:   BX248345
- RefSeq:   NP_856975.1
- ProteinModelPortal:   P64185
- SMR:   P64185
- EnsemblBacteria:   EBMYCT00000015933
- GeneID:   1093711
- GenomeReviews:   BX248333_GR
- KEGG:   mbo:Mb3330c
- GeneTree:   EBGT00050000015584
- HOGENOM:   HBG720894
- OMA:   HAKLVIN
- ProtClustDB:   CLSK872167
- BioCyc:   MBOV233413:MB3330C-MONOMER
- BRENDA:   1.1.99.5
- InterPro:   IPR006076
- InterPro:   IPR000447
- PRINTS:   PR01001

Pfam domain/function: PF01266 DAO

EC number: =1.1.5.3

Molecular weight: Translated: 62778; Mature: 62647

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: PS00977 FAD_G3PDH_1; PS00978 FAD_G3PDH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNPIQAPDGGQGWPAAALGPAQRAVAWKRLGTEQFDVVVIGGGVVGSGCALDAATRGLK
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEECCEECCCCCHHHHCCCEE
VALVEARDLASGTSSRSSKMFHGGLRYLEQLEFGLVREALYERELSLTTLAPHLVKPLPF
EEEEEHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHH
LFPLTKRWWERPYIAAGIFLYDRLGGAKSVPAQRHFTRAGALRLSPGLKRSSLIGGIRYY
HHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCHHHHHHHCCCEEECCCCCHHHHHCCHHHH
DTVVDDARHTMTVARTAAHYGAVVRCSTQVVALLREGDRVIGVGVRDSENGAVAEVRGHV
HHHHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHHCCCEEEEEEEEECCCCCEEEEECEE
VVNATGVWTDEIQALSKQRGRFQVRASKGVHVVVPRDRIVSDVAMILRTEKSVMFVIPWG
EEEECCCCHHHHHHHHHCCCCEEEEECCCEEEEECCHHHHHHHHHHHCCCCCEEEEEECC
SHWIIGTTDTDWNLDLAHPAATKADIDYILGTVNAVLATPLTHADIDGVYAGLRPLLAGE
CEEEEECCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCC
SDDTSKLSREHAVAVPAAGLVAIAGGKYTTYRVMAADAIDAAVQFIPARVAPSITEKVSL
CCCHHHHHHHHEEECCCCCEEEEECCCEEEEEEEEHHHHHHHHHHHHHHCCCHHHHHHHH
LGADGYFALVNQAEHVGALQGLHPYRVRHLLDRYGSLISDVLAMAASDPSLLSPITEAPG
CCCCCCEEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCC
YLKVEAAYAAAAEGALHLEDILARRMRISIEYPHRGVDCAREVAEVVAPVLGWTAADIDR
CEEEEEHHHHHHCCCHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHCCHHHHHHH
EVANYMARVEAEVLSQAQPDDVSADMLRASAPEARAEILEPVPLD
HHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCHHHHHHCCCCCCC
>Mature Secondary Structure 
SNPIQAPDGGQGWPAAALGPAQRAVAWKRLGTEQFDVVVIGGGVVGSGCALDAATRGLK
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEECCEECCCCCHHHHCCCEE
VALVEARDLASGTSSRSSKMFHGGLRYLEQLEFGLVREALYERELSLTTLAPHLVKPLPF
EEEEEHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHH
LFPLTKRWWERPYIAAGIFLYDRLGGAKSVPAQRHFTRAGALRLSPGLKRSSLIGGIRYY
HHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCHHHHHHHCCCEEECCCCCHHHHHCCHHHH
DTVVDDARHTMTVARTAAHYGAVVRCSTQVVALLREGDRVIGVGVRDSENGAVAEVRGHV
HHHHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHHCCCEEEEEEEEECCCCCEEEEECEE
VVNATGVWTDEIQALSKQRGRFQVRASKGVHVVVPRDRIVSDVAMILRTEKSVMFVIPWG
EEEECCCCHHHHHHHHHCCCCEEEEECCCEEEEECCHHHHHHHHHHHCCCCCEEEEEECC
SHWIIGTTDTDWNLDLAHPAATKADIDYILGTVNAVLATPLTHADIDGVYAGLRPLLAGE
CEEEEECCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCC
SDDTSKLSREHAVAVPAAGLVAIAGGKYTTYRVMAADAIDAAVQFIPARVAPSITEKVSL
CCCHHHHHHHHEEECCCCCEEEEECCCEEEEEEEEHHHHHHHHHHHHHHCCCHHHHHHHH
LGADGYFALVNQAEHVGALQGLHPYRVRHLLDRYGSLISDVLAMAASDPSLLSPITEAPG
CCCCCCEEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCC
YLKVEAAYAAAAEGALHLEDILARRMRISIEYPHRGVDCAREVAEVVAPVLGWTAADIDR
CEEEEEHHHHHHCCCHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHCCHHHHHHH
EVANYMARVEAEVLSQAQPDDVSADMLRASAPEARAEILEPVPLD
HHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972