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The map label for this gene is wbbL1

Identifier: 148663128

GI number: 148663128

Start: 3656762

End: 3657667

Strand: Reverse

Name: wbbL1

Synonym: MRA_3306

Alternate gene names: 148663128

Gene position: 3657667-3656762 (Counterclockwise)

Preceding gene: 148663129

Following gene: 148663127

Centisome position: 82.75

GC content: 67.66

Gene sequence:

>906_bases
GTGGTAGCGGTGACCTACTCGCCGGGGCCCCATCTAGAGCGGTTCCTGGCGTCGTTGTCGCTGGCCACCGAGCGGCCGGT
CAGCGTGCTGTTGGCAGACAACGGCTCCACCGACGGCACCCCGCAGGCCGCGGTGCAGCGCTACCCCAACGTGCGGCTGC
TGCCCACAGGGGCCAACCTCGGGTACGGAACCGCGGTGAATCGGACGATCGCCCAGCTCGGTGAAATGGCGGGCGATGCC
GGCGAACCCTGGGTCGATGACTGGGTGATCGTGGCCAACCCGGACGTGCAATGGGGCCCGGGCAGTATCGATGCACTACT
GGACGCCGCCTCCCGCTGGCCCCGCGCGGGCGCGCTGGGCCCGCTGATTCGGGACCCCGACGGGTCGGTGTACCCGTCGG
CGCGGCAGATGCCCAGCCTGATCCGCGGCGGCATGCACGCAGTGCTCGGGCCGTTCTGGCCGCGCAATCCGTGGACGACG
GCCTACCGGCAGGAGCGGCTGGAGCCCAGTGAACGGCCGGTGGGTTGGTTGTCGGGGTCTTGCCTACTGGTGCGCCGGTC
GGCGTTTGGCCAGGTCGGCGGATTCGACGAACGTTACTTCATGTACATGGAGGACGTCGACCTTGGCGACCGGCTTGGCA
AAGCCGGTTGGCTGTCGGTGTATGTGCCGTCAGCCGAGGTTCTGCACCACAAGGCGCATTCGACGGGTCGCGACCCGGCA
AGCCATCTGGCCGCCCATCACAAAAGCACCTATATCTTCTTAGCCGACCGACATTCTGGTTGGTGGCGGGCTCCGCTGCG
CTGGACCCTGCGGGGATCACTGGCGCTGCGTTCCCACCTCATGGTGCGCAGTTCACTGCGCAGGTCCCGCAGACGGAAAC
TGAAGCTGGTAGAAGGGCGGCACTGA

Upstream 100 bases:

>100_bases
CGGCACTGGCGCAGCGCACTGGCCACGGCGCTGGCAGCACCTGCGAACTCAACTTCGATCGATCGACGGTTACCCTCAAC
GCGTGACTGACGTCCTGCCG

Downstream 100 bases:

>100_bases
GTTGGCAACTCACCAAGTCGATGCGGTGGTCCTGGTCGGTGGCAAGGGTACCCGACTGCGGCCGTTGACGCTGTCGGCGC
CCAAGCCAATGCTGCCTACC

Product: putative dTDP-RHA:A-D-GlcNAc-diphosphoryl polyprenol,A-3-L-rhamnosyltransferase WbbL1

Products: NA

Alternate protein names: Rhamnosyltransferase

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MVAVTYSPGPHLERFLASLSLATERPVSVLLADNGSTDGTPQAAVQRYPNVRLLPTGANLGYGTAVNRTIAQLGEMAGDA
GEPWVDDWVIVANPDVQWGPGSIDALLDAASRWPRAGALGPLIRDPDGSVYPSARQMPSLIRGGMHAVLGPFWPRNPWTT
AYRQERLEPSERPVGWLSGSCLLVRRSAFGQVGGFDERYFMYMEDVDLGDRLGKAGWLSVYVPSAEVLHHKAHSTGRDPA
SHLAAHHKSTYIFLADRHSGWWRAPLRWTLRGSLALRSHLMVRSSLRRSRRRKLKLVEGRH

Sequences:

>Translated_301_residues
MVAVTYSPGPHLERFLASLSLATERPVSVLLADNGSTDGTPQAAVQRYPNVRLLPTGANLGYGTAVNRTIAQLGEMAGDA
GEPWVDDWVIVANPDVQWGPGSIDALLDAASRWPRAGALGPLIRDPDGSVYPSARQMPSLIRGGMHAVLGPFWPRNPWTT
AYRQERLEPSERPVGWLSGSCLLVRRSAFGQVGGFDERYFMYMEDVDLGDRLGKAGWLSVYVPSAEVLHHKAHSTGRDPA
SHLAAHHKSTYIFLADRHSGWWRAPLRWTLRGSLALRSHLMVRSSLRRSRRRKLKLVEGRH
>Mature_301_residues
MVAVTYSPGPHLERFLASLSLATERPVSVLLADNGSTDGTPQAAVQRYPNVRLLPTGANLGYGTAVNRTIAQLGEMAGDA
GEPWVDDWVIVANPDVQWGPGSIDALLDAASRWPRAGALGPLIRDPDGSVYPSARQMPSLIRGGMHAVLGPFWPRNPWTT
AYRQERLEPSERPVGWLSGSCLLVRRSAFGQVGGFDERYFMYMEDVDLGDRLGKAGWLSVYVPSAEVLHHKAHSTGRDPA
SHLAAHHKSTYIFLADRHSGWWRAPLRWTLRGSLALRSHLMVRSSLRRSRRRKLKLVEGRH

Specific function: Involved in the biosynthesis of the mycolylarabinogalactan-peptidoglycan (mAGP) complex, an essential component the mycobacterial cell wall. Catalyzes the transfer of the rhamnosyl moiety from dTDP-rhamnosyl (dTDP-Rha) onto the undecaprenyl-pyrophosphoryl

COG id: COG1216

COG function: function code R; Predicted glycosyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 2 family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): WBBL_MYCTU (Q7D5T2)

Other databases:

- EMBL:   BX842582
- EMBL:   AE000516
- PIR:   B70978
- RefSeq:   NP_337892.1
- RefSeq:   YP_177952.1
- ProteinModelPortal:   Q7D5T2
- EnsemblBacteria:   EBMYCT00000000321
- EnsemblBacteria:   EBMYCT00000072998
- GeneID:   888714
- GeneID:   923189
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT3365
- KEGG:   mtu:Rv3265c
- TIGR:   MT3365
- TubercuList:   Rv3265c
- GeneTree:   EBGT00050000015527
- HOGENOM:   HBG701353
- OMA:   HAKGHAA
- ProtClustDB:   CLSK799364
- BioCyc:   MetaCyc:MONOMER-15253
- GO:   GO:0040007
- InterPro:   IPR001173

Pfam domain/function: PF00535 Glycos_transf_2

EC number: NA

Molecular weight: Translated: 33295; Mature: 33295

Theoretical pI: Translated: 10.32; Mature: 10.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVAVTYSPGPHLERFLASLSLATERPVSVLLADNGSTDGTPQAAVQRYPNVRLLPTGANL
CEEEEECCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHCCCCEEEECCCCC
GYGTAVNRTIAQLGEMAGDAGEPWVDDWVIVANPDVQWGPGSIDALLDAASRWPRAGALG
CCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCC
PLIRDPDGSVYPSARQMPSLIRGGMHAVLGPFWPRNPWTTAYRQERLEPSERPVGWLSGS
CCEECCCCCCCCCHHHHHHHHHCCHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCCEECCC
CLLVRRSAFGQVGGFDERYFMYMEDVDLGDRLGKAGWLSVYVPSAEVLHHKAHSTGRDPA
EEEEEEHHCCCCCCCCCEEEEEEECCCHHHHCCCCCEEEEECCCHHHHHHHHHCCCCCHH
SHLAAHHKSTYIFLADRHSGWWRAPLRWTLRGSLALRSHLMVRSSLRRSRRRKLKLVEGR
HHHHHHCCCEEEEEEECCCCEEECCEEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCC
H
C
>Mature Secondary Structure
MVAVTYSPGPHLERFLASLSLATERPVSVLLADNGSTDGTPQAAVQRYPNVRLLPTGANL
CEEEEECCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHCCCCEEEECCCCC
GYGTAVNRTIAQLGEMAGDAGEPWVDDWVIVANPDVQWGPGSIDALLDAASRWPRAGALG
CCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCC
PLIRDPDGSVYPSARQMPSLIRGGMHAVLGPFWPRNPWTTAYRQERLEPSERPVGWLSGS
CCEECCCCCCCCCHHHHHHHHHCCHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCCEECCC
CLLVRRSAFGQVGGFDERYFMYMEDVDLGDRLGKAGWLSVYVPSAEVLHHKAHSTGRDPA
EEEEEEHHCCCCCCCCCEEEEEEECCCHHHHCCCCCEEEEECCCHHHHHHHHHCCCCCHH
SHLAAHHKSTYIFLADRHSGWWRAPLRWTLRGSLALRSHLMVRSSLRRSRRRKLKLVEGR
HHHHHHCCCEEEEEEECCCCEEECCEEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCC
H
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036