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The map label for this gene is mtrB [H]

Identifier: 148663108

GI number: 148663108

Start: 3635693

End: 3637396

Strand: Reverse

Name: mtrB [H]

Synonym: MRA_3286

Alternate gene names: 148663108

Gene position: 3637396-3635693 (Counterclockwise)

Preceding gene: 148663109

Following gene: 148663107

Centisome position: 82.29

GC content: 66.55

Gene sequence:

>1704_bases
ATGATCTTCGGCTCGCGCCGACGCATTCGGGGTCGCCGGGGTCGCTCTGGCCCGATGACACGGGGCCTCAGTGCGTTGAG
TCGAGCCGTAGCTGTCGCGTGGCGCCGATCGCTGCAGCTGCGGGTCGTGGCGCTGACCCTTGGACTGTCGCTAGCCGTCA
TCCTGGCGCTTGGCTTTGTGCTGACCAGCCAGGTCACCAATCGTGTCCTCGACATCAAGGTCAGGGCGGCGATCGACCAG
ATCGAGCGGGCACGCACCACCGTCAGCGGGATCGTCAACGGTGAGGAGACGCGCTCACTGGACAGTAGCCTGCAGCTTGC
GCGCAACACTCTGACGTCGAAAACCGACCCCGCTTCGGGGGCTGGCCTCGCCGGTGCGTTCGATGCGGTGCTGATGGTGC
CGGGTGATGGGCCGCGCGCTGCCTCTACTGCCGGACCCGTCGATCAGGTGCCCAACGCGCTGCGCGGCTTCGTCAAGGCC
GGGCAGGCCGCCTACCAGTACGCCACGGTGCAGACCGAAGGTTTCTCCGGGCCGGCCCTGATCATCGGGACTCCGACGTT
GTCGCGGGTGGCCAACCTGGAGCTATACCTGATCTTTCCGCTGGCGAGCGAGCAAGCCACGATCACGCTGGTGCGTGGCA
CGATGGCCACCGGCGGCCTGGTACTGCTAGTCCTGCTCGCCGGCATTGCGCTGCTGGTGTCGCGTCAGGTGGTGGTGCCG
GTGCGGTCGGCGTCGCGGATCGCCGAACGTTTCGCCGAGGGACATCTGTCCGAACGCATGCCGGTGCGCGGCGAGGACGA
CATGGCCAGGCTGGCGGTGTCGTTCAACGACATGGCCGAGAGCCTGTCCCGACAGATCGCCCAGCTGGAGGAGTTCGGCA
ACCTACAGCGCCGGTTCACCTCCGACGTCAGCCACGAACTGCGTACGCCGCTGACCACGGTGCGGATGGCGGCCGACTTG
ATCTATGACCACAGCGCCGACCTCGACCCCACGCTGCGGCGGTCCACCGAGTTGATGGTTAGCGAGCTGGACCGATTCGA
GACGTTGCTCAACGACCTGCTGGAGATCTCGCGGCATGACGCCGGGGTGGCCGAGTTGTCGGTTGAGGCGGTCGACTTGC
GCACAACGGTCAACAACGCGCTCGGCAATGTGGGCCACCTGGCCGAGGAGGCCGGTATCGAGTTGCTGGTGGATCTGCCC
GCCGAGCAGGTGATCGCGGAGGTCGATGCGCGTCGGGTAGAACGGATCCTGCGCAATCTGATTGCCAATGCCATCGACCA
CGCCGAACACAAACCGGTGCGGATCCGGATGGCCGCCGACGAAGACACGGTCGCCGTCACCGTGCGTGACTACGGGGTTG
GGCTGCGGCCTGGTGAGGAGAAGCTGGTGTTTAGCCGGTTCTGGCGCTCGGATCCCTCACGGGTACGTCGGTCCGGCGGC
ACCGGGCTGGGTTTGGCGATCAGCGTCGAGGATGCCCGATTGCACCAGGGTCGGCTTGAGGCGTGGGGCGAACCCGGCGA
GGGCGCCTGCTTCCGGCTGACGCTTCCGATGGTGCGCGGCCACAAGGTCACCACCAGCCCGCTGCCCATGAAACCGATCC
CGCAGCCAGTTCTGCAACCGGTCGCGCAACCGAATCCGCAACCGATGCCACCGGAATACAAGGAACGTCAGCGCCCACGT
GAGCACGCGGAGTGGAGCGGTTGA

Upstream 100 bases:

>100_bases
ACTGTGGTGCTGACCGTTCGAGGAGTGGGGTACAAGGCCGGACCTCCGTGATCCGCGCCGGCGACGATGCAGAGCGCAGC
GATGCTAAGGAGCGGCGCCG

Downstream 100 bases:

>100_bases
TGCGGCTGACAATTTTGTTGTTCCTTGGTGCAGTGCTGGCCGGCTGTGCCAGTGTGCCCAGCACGTCGGCCCCGCAAGCC
ATCGGAACCGTCGAACGTCC

Product: two component sensory transduction histidine kinase MtrB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 567; Mature: 567

Protein sequence:

>567_residues
MIFGSRRRIRGRRGRSGPMTRGLSALSRAVAVAWRRSLQLRVVALTLGLSLAVILALGFVLTSQVTNRVLDIKVRAAIDQ
IERARTTVSGIVNGEETRSLDSSLQLARNTLTSKTDPASGAGLAGAFDAVLMVPGDGPRAASTAGPVDQVPNALRGFVKA
GQAAYQYATVQTEGFSGPALIIGTPTLSRVANLELYLIFPLASEQATITLVRGTMATGGLVLLVLLAGIALLVSRQVVVP
VRSASRIAERFAEGHLSERMPVRGEDDMARLAVSFNDMAESLSRQIAQLEEFGNLQRRFTSDVSHELRTPLTTVRMAADL
IYDHSADLDPTLRRSTELMVSELDRFETLLNDLLEISRHDAGVAELSVEAVDLRTTVNNALGNVGHLAEEAGIELLVDLP
AEQVIAEVDARRVERILRNLIANAIDHAEHKPVRIRMAADEDTVAVTVRDYGVGLRPGEEKLVFSRFWRSDPSRVRRSGG
TGLGLAISVEDARLHQGRLEAWGEPGEGACFRLTLPMVRGHKVTTSPLPMKPIPQPVLQPVAQPNPQPMPPEYKERQRPR
EHAEWSG

Sequences:

>Translated_567_residues
MIFGSRRRIRGRRGRSGPMTRGLSALSRAVAVAWRRSLQLRVVALTLGLSLAVILALGFVLTSQVTNRVLDIKVRAAIDQ
IERARTTVSGIVNGEETRSLDSSLQLARNTLTSKTDPASGAGLAGAFDAVLMVPGDGPRAASTAGPVDQVPNALRGFVKA
GQAAYQYATVQTEGFSGPALIIGTPTLSRVANLELYLIFPLASEQATITLVRGTMATGGLVLLVLLAGIALLVSRQVVVP
VRSASRIAERFAEGHLSERMPVRGEDDMARLAVSFNDMAESLSRQIAQLEEFGNLQRRFTSDVSHELRTPLTTVRMAADL
IYDHSADLDPTLRRSTELMVSELDRFETLLNDLLEISRHDAGVAELSVEAVDLRTTVNNALGNVGHLAEEAGIELLVDLP
AEQVIAEVDARRVERILRNLIANAIDHAEHKPVRIRMAADEDTVAVTVRDYGVGLRPGEEKLVFSRFWRSDPSRVRRSGG
TGLGLAISVEDARLHQGRLEAWGEPGEGACFRLTLPMVRGHKVTTSPLPMKPIPQPVLQPVAQPNPQPMPPEYKERQRPR
EHAEWSG
>Mature_567_residues
MIFGSRRRIRGRRGRSGPMTRGLSALSRAVAVAWRRSLQLRVVALTLGLSLAVILALGFVLTSQVTNRVLDIKVRAAIDQ
IERARTTVSGIVNGEETRSLDSSLQLARNTLTSKTDPASGAGLAGAFDAVLMVPGDGPRAASTAGPVDQVPNALRGFVKA
GQAAYQYATVQTEGFSGPALIIGTPTLSRVANLELYLIFPLASEQATITLVRGTMATGGLVLLVLLAGIALLVSRQVVVP
VRSASRIAERFAEGHLSERMPVRGEDDMARLAVSFNDMAESLSRQIAQLEEFGNLQRRFTSDVSHELRTPLTTVRMAADL
IYDHSADLDPTLRRSTELMVSELDRFETLLNDLLEISRHDAGVAELSVEAVDLRTTVNNALGNVGHLAEEAGIELLVDLP
AEQVIAEVDARRVERILRNLIANAIDHAEHKPVRIRMAADEDTVAVTVRDYGVGLRPGEEKLVFSRFWRSDPSRVRRSGG
TGLGLAISVEDARLHQGRLEAWGEPGEGACFRLTLPMVRGHKVTTSPLPMKPIPQPVLQPVAQPNPQPMPPEYKERQRPR
EHAEWSG

Specific function: Member of the two-component regulatory system mtrA/mtrB. Seems to function as a membrane-associated protein kinase that phosphorylates mtrA in response to environmental signals [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790346, Length=330, Percent_Identity=29.6969696969697, Blast_Score=131, Evalue=1e-31,
Organism=Escherichia coli, GI1788393, Length=286, Percent_Identity=29.3706293706294, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI1787894, Length=305, Percent_Identity=28.1967213114754, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI1789149, Length=335, Percent_Identity=25.9701492537313, Blast_Score=102, Evalue=9e-23,
Organism=Escherichia coli, GI1786783, Length=345, Percent_Identity=26.9565217391304, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI1786912, Length=340, Percent_Identity=28.8235294117647, Blast_Score=99, Evalue=9e-22,
Organism=Escherichia coli, GI87081816, Length=355, Percent_Identity=27.3239436619718, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI87082128, Length=307, Percent_Identity=26.7100977198697, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI1788549, Length=254, Percent_Identity=27.9527559055118, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI145693157, Length=242, Percent_Identity=26.8595041322314, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1788713, Length=238, Percent_Identity=26.4705882352941, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1786600, Length=237, Percent_Identity=27.4261603375527, Blast_Score=83, Evalue=6e-17,
Organism=Escherichia coli, GI1788279, Length=301, Percent_Identity=26.578073089701, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI1790436, Length=223, Percent_Identity=26.9058295964126, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI48994928, Length=225, Percent_Identity=29.3333333333333, Blast_Score=76, Evalue=7e-15,
Organism=Escherichia coli, GI1789403, Length=225, Percent_Identity=29.7777777777778, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1790551, Length=277, Percent_Identity=25.2707581227437, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1789808, Length=300, Percent_Identity=25, Blast_Score=70, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 61638; Mature: 61638

Theoretical pI: Translated: 8.99; Mature: 8.99

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFGSRRRIRGRRGRSGPMTRGLSALSRAVAVAWRRSLQLRVVALTLGLSLAVILALGFV
CCCCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHH
LTSQVTNRVLDIKVRAAIDQIERARTTVSGIVNGEETRSLDSSLQLARNTLTSKTDPASG
HHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCC
AGLAGAFDAVLMVPGDGPRAASTAGPVDQVPNALRGFVKAGQAAYQYATVQTEGFSGPAL
CCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCHHHHEEEEEEECCCCCCEE
IIGTPTLSRVANLELYLIFPLASEQATITLVRGTMATGGLVLLVLLAGIALLVSRQVVVP
EEECCHHHHHHCCEEEEEEEECCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCEEE
VRSASRIAERFAEGHLSERMPVRGEDDMARLAVSFNDMAESLSRQIAQLEEFGNLQRRFT
CHHHHHHHHHHHHCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SDVSHELRTPLTTVRMAADLIYDHSADLDPTLRRSTELMVSELDRFETLLNDLLEISRHD
HHHHHHHHCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
AGVAELSVEAVDLRTTVNNALGNVGHLAEEAGIELLVDLPAEQVIAEVDARRVERILRNL
CCHHHEEEEHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHH
IANAIDHAEHKPVRIRMAADEDTVAVTVRDYGVGLRPGEEKLVFSRFWRSDPSRVRRSGG
HHHHHHHCCCCCEEEEEECCCCEEEEEEEECCCCCCCCCHHHHHHHHHCCCHHHHHHCCC
TGLGLAISVEDARLHQGRLEAWGEPGEGACFRLTLPMVRGHKVTTSPLPMKPIPQPVLQP
CCEEEEEEECHHHHHCCHHHHCCCCCCCCEEEEEECHHCCCEEECCCCCCCCCCHHHHHH
VAQPNPQPMPPEYKERQRPREHAEWSG
HCCCCCCCCCCCHHHHCCCHHCCCCCC
>Mature Secondary Structure
MIFGSRRRIRGRRGRSGPMTRGLSALSRAVAVAWRRSLQLRVVALTLGLSLAVILALGFV
CCCCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHH
LTSQVTNRVLDIKVRAAIDQIERARTTVSGIVNGEETRSLDSSLQLARNTLTSKTDPASG
HHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCC
AGLAGAFDAVLMVPGDGPRAASTAGPVDQVPNALRGFVKAGQAAYQYATVQTEGFSGPAL
CCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCHHHHEEEEEEECCCCCCEE
IIGTPTLSRVANLELYLIFPLASEQATITLVRGTMATGGLVLLVLLAGIALLVSRQVVVP
EEECCHHHHHHCCEEEEEEEECCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCEEE
VRSASRIAERFAEGHLSERMPVRGEDDMARLAVSFNDMAESLSRQIAQLEEFGNLQRRFT
CHHHHHHHHHHHHCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SDVSHELRTPLTTVRMAADLIYDHSADLDPTLRRSTELMVSELDRFETLLNDLLEISRHD
HHHHHHHHCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
AGVAELSVEAVDLRTTVNNALGNVGHLAEEAGIELLVDLPAEQVIAEVDARRVERILRNL
CCHHHEEEEHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHH
IANAIDHAEHKPVRIRMAADEDTVAVTVRDYGVGLRPGEEKLVFSRFWRSDPSRVRRSGG
HHHHHHHCCCCCEEEEEECCCCEEEEEEEECCCCCCCCCHHHHHHHHHCCCHHHHHHCCC
TGLGLAISVEDARLHQGRLEAWGEPGEGACFRLTLPMVRGHKVTTSPLPMKPIPQPVLQP
CCEEEEEEECHHHHHCCHHHHCCCCCCCCEEEEEECHHCCCEEECCCCCCCCCCHHHHHH
VAQPNPQPMPPEYKERQRPREHAEWSG
HCCCCCCCCCCCHHHHCCCHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]