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The map label for this gene is nuoG [H]

Identifier: 148663006

GI number: 148663006

Start: 3528902

End: 3531322

Strand: Direct

Name: nuoG [H]

Synonym: MRA_3184

Alternate gene names: 148663006

Gene position: 3528902-3531322 (Clockwise)

Preceding gene: 148663005

Following gene: 148663007

Centisome position: 79.84

GC content: 68.48

Gene sequence:

>2421_bases
GTGACCCAGGCGGCCGACACTGACATCCGGGTAGGCCAACCGGAGATGGTGACACTGACCATCGACGGCGTCGAAATCAG
CGTCCCCAAGGGCACGTTGGTGATTCGCGCCGCCGAACTGATGGGAATCCAGATCCCGCGATTCTGCGACCACCCGCTGC
TGGAGCCCGTCGGCGCCTGCCGGCAATGCCTGGTCGAGGTCGAAGGGCAACGCAAGCCGCTGGCGTCGTGCACCACCGTG
GCCACCGACGACATGGTGGTGCGCACCCAACTCACCTCCGAGATTGCCGACAAGGCCCAGCACGGTGTGATGGAACTGCT
GCTGATCAACCATCCGCTGGATTGCCCGATGTGCGACAAGGGCGGTGAATGCCCGCTGCAAAACCAGGCAATGTCTAACG
GCCGCACGGATTCTCGCTTCACCGAGGCCAAACGTACCTTCGCCAAACCGATCAACATCTCCGCGCAGGTGCTGCTGGAC
CGCGAACGTTGCATCCTGTGCGCCCGCTGCACCCGGTTCTCCGACCAGATCGCCGGCGATCCGTTCATCGATATGCAGGA
GCGCGGCGCCCTGCAGCAGGTCGGTATCTACGCCGATGAACCGTTCGAGTCGTACTTCTCCGGCAACACGGTGCAGATCT
GCCCGGTGGGGGCGCTAACGGGGACCGCCTACCGGTTCCGCGCGCGTCCGTTCGATTTGGTCTCCAGCCCCAGCGTCTGC
GAGCACTGCGCGTCGGGCTGCGCGCAACGCACCGACCATCGCCGCGGCAAGGTGCTGCGGCGGCTGGCCGGTGACGACCC
GGAAGTCAACGAGGAGTGGAACTGCGACAAGGGCCGGTGGGCCTTCACGTACGCGACCCAGCCGGACGTGATCACCACTC
CCCTGATCCGCGACGGTGGGGACCCCAAGGGCGCGCTGGTGCCCACCTCGTGGTCGCACGCAATGGCGGTGGCCGCCCAG
GGACTGGCGGCAGCGCGGGGCCGCACCGGGGTGCTGGTCGGCGGCCGAGTGACCTGGGAGGACGCCTACGCGTACGCCAA
GTTCGCGCGGATCACGTTGGGCACCAACGACATCGACTTCCGCGCCCGGCCGCACTCGGCCGAGGAGGCCGACTTCCTGG
CGGCCCGCATCGCCGGGCGGCATATGGCGGTCAGCTATGCCGATTTGGAATCGGCTCCGGTGGTGCTGCTGGTGGGATTC
GAGCCCGAAGACGAGTCGCCGATCGTGTTTCTGCGGTTACGCAAGGCCGCTCGCAGACACCGCGTCCCGGTGTACACGAT
CGCCCCCTTTGCCACTGGTGGCCTGCACAAAATGTCGGGCCGGCTGATCAAAACCGTTCCTGGTGGCGAACCCGCGGCGC
TGGACGATCTGGCCACCGGTGCAGTGGGCGACCTGCTGGCCACCCCGGGCGCGGTCATCATAGTCGGGGAGCGCTTGGCC
ACGGTACCGGGCGGATTGTCGGCGGCCGCTCGGCTGGCCGATACGACCGGCGCCCGTTTGGCGTGGGTGCCGCGGCGGGC
GGGGGAACGCGGAGCGCTGGAAGCCGGAGCGTTGCCCACGCTGTTACCCGGTGGCCGCCCGCTGGCCGACGAGGTCGCCC
GCGCGCAGGTGTGTGCGGCGTGGCATATCGCCGAATTGCCTGCCGCGGCTGGACGGGACGCCGACGGCATCCTGGCCGCC
GCTGCCGACGAGACGTTGGCTGCGCTGCTGGTCGGGGGTATCGAACCCGCGGACTTCGCCGACCCGGACGCCGTGCTGGC
CGCGTTGGACGCCACCGGTTTCGTGGTCAGCCTGGAGCTGCGACACAGTACGGTCACCGAACGCGCCGACGTGGTGTTCC
CGGTCGCGCCGACGACCCAGAAAGCCGGCGCGTTCGTCAACTGGGAGGGTCGCTACCGTACATTCGAACCCGCGCTGCGC
GGCAGCACACTGCAAGCTGGCCAGTCGGATCACCGGGTGCTGGACGCGTTGGCCGACGACATGGGTGTCCATCTGGGCGT
GCCCACCGTGGAGGCGGCCCGCGAGGAGCTGGCCGCGCTCGGTATCTGGGACGGCAAACACGCTGCCGGTCCCCACATCG
CGGCCACCGGGCCGACCCAACCCGAAGCTGGTGAGGCGATCTTGACCGGGTGGCGGATGCTCCTCGACGAGGGCCGCCTG
CAGGACGGCGAACCATATCTGGCCGGTACCGCGCGCACACCCGTGGTACGGCTGTCGCCGGATACGGCAGCCGAGATCGG
CGCCGCCGATGGCGAGGCGGTCACGGTCAGCACGTCACGCGGCTCAATCACCTTGCCGTGCAGTGTCACCGACATGCCCG
ACCGCGTCGTGTGGCTTCCGCTGAACTCGGCGGGCTCGACGGTGCACCGACAGCTGAGGGTGACAATCGGCAGCATCGTG
AAAATCGGAGCGGGCTCATGA

Upstream 100 bases:

>100_bases
CGATCAAGCACTTCCGCGACGAGTACCTGGCCCACGTCGAAGGAGGCGGTTGCCCATTCGACCCCCGAGACTCCATGCTC
GTCGCGAACGGAGTGGACGC

Downstream 100 bases:

>100_bases
GCGTCTCCCCTTGCCGCGAGCGCGCGTGTTCCCCCGCAAGCGGGAGGTGCCCCCAGTACGCCGACACACCGATTTTGATG
TACCAGTGCGGACCCTCGCG

Product: NADH dehydrogenase subunit G

Products: NA

Alternate protein names: NADH dehydrogenase I subunit G; NDH-1 subunit G [H]

Number of amino acids: Translated: 806; Mature: 805

Protein sequence:

>806_residues
MTQAADTDIRVGQPEMVTLTIDGVEISVPKGTLVIRAAELMGIQIPRFCDHPLLEPVGACRQCLVEVEGQRKPLASCTTV
ATDDMVVRTQLTSEIADKAQHGVMELLLINHPLDCPMCDKGGECPLQNQAMSNGRTDSRFTEAKRTFAKPINISAQVLLD
RERCILCARCTRFSDQIAGDPFIDMQERGALQQVGIYADEPFESYFSGNTVQICPVGALTGTAYRFRARPFDLVSSPSVC
EHCASGCAQRTDHRRGKVLRRLAGDDPEVNEEWNCDKGRWAFTYATQPDVITTPLIRDGGDPKGALVPTSWSHAMAVAAQ
GLAAARGRTGVLVGGRVTWEDAYAYAKFARITLGTNDIDFRARPHSAEEADFLAARIAGRHMAVSYADLESAPVVLLVGF
EPEDESPIVFLRLRKAARRHRVPVYTIAPFATGGLHKMSGRLIKTVPGGEPAALDDLATGAVGDLLATPGAVIIVGERLA
TVPGGLSAAARLADTTGARLAWVPRRAGERGALEAGALPTLLPGGRPLADEVARAQVCAAWHIAELPAAAGRDADGILAA
AADETLAALLVGGIEPADFADPDAVLAALDATGFVVSLELRHSTVTERADVVFPVAPTTQKAGAFVNWEGRYRTFEPALR
GSTLQAGQSDHRVLDALADDMGVHLGVPTVEAAREELAALGIWDGKHAAGPHIAATGPTQPEAGEAILTGWRMLLDEGRL
QDGEPYLAGTARTPVVRLSPDTAAEIGAADGEAVTVSTSRGSITLPCSVTDMPDRVVWLPLNSAGSTVHRQLRVTIGSIV
KIGAGS

Sequences:

>Translated_806_residues
MTQAADTDIRVGQPEMVTLTIDGVEISVPKGTLVIRAAELMGIQIPRFCDHPLLEPVGACRQCLVEVEGQRKPLASCTTV
ATDDMVVRTQLTSEIADKAQHGVMELLLINHPLDCPMCDKGGECPLQNQAMSNGRTDSRFTEAKRTFAKPINISAQVLLD
RERCILCARCTRFSDQIAGDPFIDMQERGALQQVGIYADEPFESYFSGNTVQICPVGALTGTAYRFRARPFDLVSSPSVC
EHCASGCAQRTDHRRGKVLRRLAGDDPEVNEEWNCDKGRWAFTYATQPDVITTPLIRDGGDPKGALVPTSWSHAMAVAAQ
GLAAARGRTGVLVGGRVTWEDAYAYAKFARITLGTNDIDFRARPHSAEEADFLAARIAGRHMAVSYADLESAPVVLLVGF
EPEDESPIVFLRLRKAARRHRVPVYTIAPFATGGLHKMSGRLIKTVPGGEPAALDDLATGAVGDLLATPGAVIIVGERLA
TVPGGLSAAARLADTTGARLAWVPRRAGERGALEAGALPTLLPGGRPLADEVARAQVCAAWHIAELPAAAGRDADGILAA
AADETLAALLVGGIEPADFADPDAVLAALDATGFVVSLELRHSTVTERADVVFPVAPTTQKAGAFVNWEGRYRTFEPALR
GSTLQAGQSDHRVLDALADDMGVHLGVPTVEAAREELAALGIWDGKHAAGPHIAATGPTQPEAGEAILTGWRMLLDEGRL
QDGEPYLAGTARTPVVRLSPDTAAEIGAADGEAVTVSTSRGSITLPCSVTDMPDRVVWLPLNSAGSTVHRQLRVTIGSIV
KIGAGS
>Mature_805_residues
TQAADTDIRVGQPEMVTLTIDGVEISVPKGTLVIRAAELMGIQIPRFCDHPLLEPVGACRQCLVEVEGQRKPLASCTTVA
TDDMVVRTQLTSEIADKAQHGVMELLLINHPLDCPMCDKGGECPLQNQAMSNGRTDSRFTEAKRTFAKPINISAQVLLDR
ERCILCARCTRFSDQIAGDPFIDMQERGALQQVGIYADEPFESYFSGNTVQICPVGALTGTAYRFRARPFDLVSSPSVCE
HCASGCAQRTDHRRGKVLRRLAGDDPEVNEEWNCDKGRWAFTYATQPDVITTPLIRDGGDPKGALVPTSWSHAMAVAAQG
LAAARGRTGVLVGGRVTWEDAYAYAKFARITLGTNDIDFRARPHSAEEADFLAARIAGRHMAVSYADLESAPVVLLVGFE
PEDESPIVFLRLRKAARRHRVPVYTIAPFATGGLHKMSGRLIKTVPGGEPAALDDLATGAVGDLLATPGAVIIVGERLAT
VPGGLSAAARLADTTGARLAWVPRRAGERGALEAGALPTLLPGGRPLADEVARAQVCAAWHIAELPAAAGRDADGILAAA
ADETLAALLVGGIEPADFADPDAVLAALDATGFVVSLELRHSTVTERADVVFPVAPTTQKAGAFVNWEGRYRTFEPALRG
STLQAGQSDHRVLDALADDMGVHLGVPTVEAAREELAALGIWDGKHAAGPHIAATGPTQPEAGEAILTGWRMLLDEGRLQ
DGEPYLAGTARTPVVRLSPDTAAEIGAADGEAVTVSTSRGSITLPCSVTDMPDRVVWLPLNSAGSTVHRQLRVTIGSIVK
IGAGS

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be menaquinone. Couples the redox reaction to proton transloca

COG id: COG1034

COG function: function code C; NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI33519475, Length=683, Percent_Identity=31.6251830161054, Blast_Score=254, Evalue=2e-67,
Organism=Escherichia coli, GI145693161, Length=413, Percent_Identity=30.9927360774818, Blast_Score=171, Evalue=1e-43,
Organism=Escherichia coli, GI3868721, Length=508, Percent_Identity=23.2283464566929, Blast_Score=94, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17565758, Length=699, Percent_Identity=32.0457796852647, Blast_Score=257, Evalue=2e-68,
Organism=Caenorhabditis elegans, GI32566231, Length=645, Percent_Identity=33.1782945736434, Blast_Score=253, Evalue=3e-67,
Organism=Caenorhabditis elegans, GI193209088, Length=262, Percent_Identity=43.1297709923664, Blast_Score=201, Evalue=1e-51,
Organism=Drosophila melanogaster, GI24640559, Length=706, Percent_Identity=31.8696883852691, Blast_Score=260, Evalue=2e-69,
Organism=Drosophila melanogaster, GI24640557, Length=706, Percent_Identity=31.8696883852691, Blast_Score=260, Evalue=2e-69,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006963
- InterPro:   IPR000283
- InterPro:   IPR010228
- InterPro:   IPR019574 [H]

Pfam domain/function: PF00111 Fer2; PF00384 Molybdopterin; PF01568 Molydop_binding; PF10588 NADH-G_4Fe-4S_3 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 85425; Mature: 85294

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: PS00641 COMPLEX1_75K_1 ; PS00642 COMPLEX1_75K_2 ; PS00643 COMPLEX1_75K_3 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQAADTDIRVGQPEMVTLTIDGVEISVPKGTLVIRAAELMGIQIPRFCDHPLLEPVGAC
CCCCCCCCEECCCCCEEEEEECCEEEECCCCEEEEEEEHHHCCCCCHHCCCHHHHHHHHH
RQCLVEVEGQRKPLASCTTVATDDMVVRTQLTSEIADKAQHGVMELLLINHPLDCPMCDK
HHHHHHHCCCCCCCCHHEEECCCCEEEEHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCC
GGECPLQNQAMSNGRTDSRFTEAKRTFAKPINISAQVLLDRERCILCARCTRFSDQIAGD
CCCCCCCHHHHCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCEEEEHHHHHHHHHHCCC
PFIDMQERGALQQVGIYADEPFESYFSGNTVQICPVGALTGTAYRFRARPFDLVSSPSVC
CCCCHHHCCCHHHCCCCCCCCHHHHHCCCEEEEEECCCCCCCEEEEECCCCCCCCCCHHH
EHCASGCAQRTDHRRGKVLRRLAGDDPEVNEEWNCDKGRWAFTYATQPDVITTPLIRDGG
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCCEECCCEECCC
DPKGALVPTSWSHAMAVAAQGLAAARGRTGVLVGGRVTWEDAYAYAKFARITLGTNDIDF
CCCCCEECCCCHHHHHHHHHHHHHHCCCCEEEECCEEEHHHHHHEEEEEEEEECCCCCEE
RARPHSAEEADFLAARIAGRHMAVSYADLESAPVVLLVGFEPEDESPIVFLRLRKAARRH
EECCCCCCHHHHHHHHHCCCEEEEEEECCCCCCEEEEEECCCCCCCCEEEEEEHHHHHHC
RVPVYTIAPFATGGLHKMSGRLIKTVPGGEPAALDDLATGAVGDLLATPGAVIIVGERLA
CCCEEEECCCCCCCHHHHCCCEEEECCCCCCCHHHHHHHCHHHHHHHCCCEEEEECCHHC
TVPGGLSAAARLADTTGARLAWVPRRAGERGALEAGALPTLLPGGRPLADEVARAQVCAA
CCCCCHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
WHIAELPAAAGRDADGILAAAADETLAALLVGGIEPADFADPDAVLAALDATGFVVSLEL
HHHHHCCCCCCCCCCCEEEECHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCEEEEEEE
RHSTVTERADVVFPVAPTTQKAGAFVNWEGRYRTFEPALRGSTLQAGQSDHRVLDALADD
CCCHHCCCCCEEEECCCCCHHCCEEEEECCCCEEECHHHCCCCCCCCCCHHHHHHHHHHH
MGVHLGVPTVEAAREELAALGIWDGKHAAGPHIAATGPTQPEAGEAILTGWRMLLDEGRL
CCCEECCCCHHHHHHHHHEEECCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHCCCC
QDGEPYLAGTARTPVVRLSPDTAAEIGAADGEAVTVSTSRGSITLPCSVTDMPDRVVWLP
CCCCCEEECCCCCCEEEECCCCHHHCCCCCCCEEEEEECCCCEEEEEECCCCCCCEEEEE
LNSAGSTVHRQLRVTIGSIVKIGAGS
ECCCCHHHHHHHHEEECCEEEECCCC
>Mature Secondary Structure 
TQAADTDIRVGQPEMVTLTIDGVEISVPKGTLVIRAAELMGIQIPRFCDHPLLEPVGAC
CCCCCCCEECCCCCEEEEEECCEEEECCCCEEEEEEEHHHCCCCCHHCCCHHHHHHHHH
RQCLVEVEGQRKPLASCTTVATDDMVVRTQLTSEIADKAQHGVMELLLINHPLDCPMCDK
HHHHHHHCCCCCCCCHHEEECCCCEEEEHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCC
GGECPLQNQAMSNGRTDSRFTEAKRTFAKPINISAQVLLDRERCILCARCTRFSDQIAGD
CCCCCCCHHHHCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCEEEEHHHHHHHHHHCCC
PFIDMQERGALQQVGIYADEPFESYFSGNTVQICPVGALTGTAYRFRARPFDLVSSPSVC
CCCCHHHCCCHHHCCCCCCCCHHHHHCCCEEEEEECCCCCCCEEEEECCCCCCCCCCHHH
EHCASGCAQRTDHRRGKVLRRLAGDDPEVNEEWNCDKGRWAFTYATQPDVITTPLIRDGG
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCCEECCCEECCC
DPKGALVPTSWSHAMAVAAQGLAAARGRTGVLVGGRVTWEDAYAYAKFARITLGTNDIDF
CCCCCEECCCCHHHHHHHHHHHHHHCCCCEEEECCEEEHHHHHHEEEEEEEEECCCCCEE
RARPHSAEEADFLAARIAGRHMAVSYADLESAPVVLLVGFEPEDESPIVFLRLRKAARRH
EECCCCCCHHHHHHHHHCCCEEEEEEECCCCCCEEEEEECCCCCCCCEEEEEEHHHHHHC
RVPVYTIAPFATGGLHKMSGRLIKTVPGGEPAALDDLATGAVGDLLATPGAVIIVGERLA
CCCEEEECCCCCCCHHHHCCCEEEECCCCCCCHHHHHHHCHHHHHHHCCCEEEEECCHHC
TVPGGLSAAARLADTTGARLAWVPRRAGERGALEAGALPTLLPGGRPLADEVARAQVCAA
CCCCCHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
WHIAELPAAAGRDADGILAAAADETLAALLVGGIEPADFADPDAVLAALDATGFVVSLEL
HHHHHCCCCCCCCCCCEEEECHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCEEEEEEE
RHSTVTERADVVFPVAPTTQKAGAFVNWEGRYRTFEPALRGSTLQAGQSDHRVLDALADD
CCCHHCCCCCEEEECCCCCHHCCEEEEECCCCEEECHHHCCCCCCCCCCHHHHHHHHHHH
MGVHLGVPTVEAAREELAALGIWDGKHAAGPHIAATGPTQPEAGEAILTGWRMLLDEGRL
CCCEECCCCHHHHHHHHHEEECCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHCCCC
QDGEPYLAGTARTPVVRLSPDTAAEIGAADGEAVTVSTSRGSITLPCSVTDMPDRVVWLP
CCCCCEEECCCCCCEEEECCCCHHHCCCCCCCEEEEEECCCCEEEEEECCCCCCCEEEEE
LNSAGSTVHRQLRVTIGSIVKIGAGS
ECCCCHHHHHHHHEEECCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]