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The map label for this gene is 148662798

Identifier: 148662798

GI number: 148662798

Start: 3315095

End: 3316240

Strand: Reverse

Name: 148662798

Synonym: MRA_2978

Alternate gene names: NA

Gene position: 3316240-3315095 (Counterclockwise)

Preceding gene: 148662801

Following gene: 148662797

Centisome position: 75.03

GC content: 61.26

Gene sequence:

>1146_bases
GTGGGCGGACTTCGTTTCGGTTTTGTTGATGCCCTCGTGCACTCGCGGTTGCCGCCGACCCTGCCGGCACGGTCTAGCAT
GGCGGCCGCCACCGTGATGGGCGCCGACTCGTATTGGGTCGGCGACCATCTGAATGCGCTGGTGCCGCGCTCGATTGCGA
CTTCCGAATATCTCGGAATTGCGGCGAAATTCGTGCCCAAGATCGATGCCAATTACGAACCGTGGACGATGCTTGGAAAC
CTCGCCTTCGGGTTGCCCAGCCGTCTGCGACTGGGCGTGTGCGTGACCGATGCAGGTCGGCGCAATCCAGCGGTCACAGC
CCAGGCTGCCGCGACTTTGCACTTGCTTACCCGAGGCCGAGCCATATTGGGTATCGGTGTCGGGGAACGTGAAGGCAACG
AGCCCTACGGTGTGGAGTGGACCAAACCGGTGGCGCGGTTCGAAGAAGCCCTGGCCACCATTCGCGCGTTGTGGAATTCA
AACGGGGAGCTTATCTCACGTGAATCGCCATACTTTCCGTTACATAACGCCTTGTTCGACCTTCCGCCATACCGTGGGAA
ATGGCCCGAAATCTGGGTCGCGGCCCACGGGCCGCGGATGTTACGGGCCACCGGACGTTACGCCGATGCCTGGATTCCCA
TTGTTGTGGTTCGTCCCAGCGACTACAGTCGCGCACTCGAAGCGGTGCGCAGCGCGGCGTCCGATGCCGGACGCGACCCA
ATGTCGATTACTCCGGCGGCGGTGCGCGGCATCATCACTGGACGGAATCGCGACGACGTGGAAGAGGCGCTGGAATCTGT
CGTTGTGAAGATGACCGCGCTCGGGGTACCTGGGGAAGCCTGGGCGCGTCACGGCGTCGAGCATCCAATGGGAGCCGACT
TCTCCGGTGTGCAGGACATCATCCCGCAAACCATGGACAAACAGACGGTTTTGTCCTACGCGGCCAAGGTCCCGGCTGCG
CTTATGAAAGAAGTCGTCTTCAGTGGAACCCCTGACGAAGTCATCGATCAAGTAGCGGAATGGCGAGATCACGGGCTGCG
CTACGTTGTGCTGATCAACGGCAGTTTGGTTAACCCCAGCCTGCGCAAGACGGTGACGGCTGTCCTGCCGCACGCCAAGG
TTTTGCGCGGGCTCAAGAAGCTATGA

Upstream 100 bases:

>100_bases
ACCCCGGTGTTGCTCAACGCGCGACCGCGCGGACATGACTCGCTGAGGTAGCGTTCCTAGCCATGACGTTGGTCAACAGC
GTAGTAGACAAGGGGTAGGC

Downstream 100 bases:

>100_bases
TTTGCGCCACTCTCGCGAAGATGGGGTAAGCCGGCCCAGCGGCTGGCGTGCCAATCGCGGCGTGCGGCAGGCGATTTCGG
CGTGTCGAGCTTGGAACTCG

Product: N5,N10-methylenetetrahydromethanopterin reductase-related protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 381; Mature: 380

Protein sequence:

>381_residues
MGGLRFGFVDALVHSRLPPTLPARSSMAAATVMGADSYWVGDHLNALVPRSIATSEYLGIAAKFVPKIDANYEPWTMLGN
LAFGLPSRLRLGVCVTDAGRRNPAVTAQAAATLHLLTRGRAILGIGVGEREGNEPYGVEWTKPVARFEEALATIRALWNS
NGELISRESPYFPLHNALFDLPPYRGKWPEIWVAAHGPRMLRATGRYADAWIPIVVVRPSDYSRALEAVRSAASDAGRDP
MSITPAAVRGIITGRNRDDVEEALESVVVKMTALGVPGEAWARHGVEHPMGADFSGVQDIIPQTMDKQTVLSYAAKVPAA
LMKEVVFSGTPDEVIDQVAEWRDHGLRYVVLINGSLVNPSLRKTVTAVLPHAKVLRGLKKL

Sequences:

>Translated_381_residues
MGGLRFGFVDALVHSRLPPTLPARSSMAAATVMGADSYWVGDHLNALVPRSIATSEYLGIAAKFVPKIDANYEPWTMLGN
LAFGLPSRLRLGVCVTDAGRRNPAVTAQAAATLHLLTRGRAILGIGVGEREGNEPYGVEWTKPVARFEEALATIRALWNS
NGELISRESPYFPLHNALFDLPPYRGKWPEIWVAAHGPRMLRATGRYADAWIPIVVVRPSDYSRALEAVRSAASDAGRDP
MSITPAAVRGIITGRNRDDVEEALESVVVKMTALGVPGEAWARHGVEHPMGADFSGVQDIIPQTMDKQTVLSYAAKVPAA
LMKEVVFSGTPDEVIDQVAEWRDHGLRYVVLINGSLVNPSLRKTVTAVLPHAKVLRGLKKL
>Mature_380_residues
GGLRFGFVDALVHSRLPPTLPARSSMAAATVMGADSYWVGDHLNALVPRSIATSEYLGIAAKFVPKIDANYEPWTMLGNL
AFGLPSRLRLGVCVTDAGRRNPAVTAQAAATLHLLTRGRAILGIGVGEREGNEPYGVEWTKPVARFEEALATIRALWNSN
GELISRESPYFPLHNALFDLPPYRGKWPEIWVAAHGPRMLRATGRYADAWIPIVVVRPSDYSRALEAVRSAASDAGRDPM
SITPAAVRGIITGRNRDDVEEALESVVVKMTALGVPGEAWARHGVEHPMGADFSGVQDIIPQTMDKQTVLSYAAKVPAAL
MKEVVFSGTPDEVIDQVAEWRDHGLRYVVLINGSLVNPSLRKTVTAVLPHAKVLRGLKKL

Specific function: Catalyzes the reduction of the keto moiety of phthiodiolone dimycocerosates (DIM B) and glycosylated phenolphthiodiolone dimycocerosates to form the intermediate compounds phthiotriol and glycosylated phenolphthiotriol dimycocerosates during phthiocerol d

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mer family. Phthiodiolone/phenolphthiodiolone dimycocerosates ketoreductase subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PHKR_MYCBO (Q7TXK4)

Other databases:

- EMBL:   BX248344
- RefSeq:   NP_856620.1
- ProteinModelPortal:   Q7TXK4
- SMR:   Q7TXK4
- EnsemblBacteria:   EBMYCT00000014477
- GeneID:   1092130
- GenomeReviews:   BX248333_GR
- KEGG:   mbo:Mb2975c
- GeneTree:   EBGT00050000014764
- HOGENOM:   HBG567930
- OMA:   MGVTQIV
- ProtClustDB:   CLSK792185
- BioCyc:   MBOV233413:MB2975C-MONOMER
- InterPro:   IPR011251
- InterPro:   IPR016048
- Gene3D:   G3DSA:3.20.20.30

Pfam domain/function: PF00296 Bac_luciferase; SSF51679 Luciferase_like

EC number: NA

Molecular weight: Translated: 41348; Mature: 41217

Theoretical pI: Translated: 9.42; Mature: 9.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGGLRFGFVDALVHSRLPPTLPARSSMAAATVMGADSYWVGDHLNALVPRSIATSEYLGI
CCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHEECCCCEECCCHHHHHCCCHHHHHHHHHH
AAKFVPKIDANYEPWTMLGNLAFGLPSRLRLGVCVTDAGRRNPAVTAQAAATLHLLTRGR
HHHHHHCCCCCCCCHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHCCC
AILGIGVGEREGNEPYGVEWTKPVARFEEALATIRALWNSNGELISRESPYFPLHNALFD
EEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCHHHHHHC
LPPYRGKWPEIWVAAHGPRMLRATGRYADAWIPIVVVRPSDYSRALEAVRSAASDAGRDP
CCCCCCCCCEEEEEECCCCEEHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCC
MSITPAAVRGIITGRNRDDVEEALESVVVKMTALGVPGEAWARHGVEHPMGADFSGVQDI
CCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCHHHHH
IPQTMDKQTVLSYAAKVPAALMKEVVFSGTPDEVIDQVAEWRDHGLRYVVLINGSLVNPS
HHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCHH
LRKTVTAVLPHAKVLRGLKKL
HHHHHHHHCCHHHHHHHHHCC
>Mature Secondary Structure 
GGLRFGFVDALVHSRLPPTLPARSSMAAATVMGADSYWVGDHLNALVPRSIATSEYLGI
CCCHHHHHHHHHHHCCCCCCCCCCHHHHHHEECCCCEECCCHHHHHCCCHHHHHHHHHH
AAKFVPKIDANYEPWTMLGNLAFGLPSRLRLGVCVTDAGRRNPAVTAQAAATLHLLTRGR
HHHHHHCCCCCCCCHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHCCC
AILGIGVGEREGNEPYGVEWTKPVARFEEALATIRALWNSNGELISRESPYFPLHNALFD
EEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCHHHHHHC
LPPYRGKWPEIWVAAHGPRMLRATGRYADAWIPIVVVRPSDYSRALEAVRSAASDAGRDP
CCCCCCCCCEEEEEECCCCEEHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCC
MSITPAAVRGIITGRNRDDVEEALESVVVKMTALGVPGEAWARHGVEHPMGADFSGVQDI
CCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCHHHHH
IPQTMDKQTVLSYAAKVPAALMKEVVFSGTPDEVIDQVAEWRDHGLRYVVLINGSLVNPS
HHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCHH
LRKTVTAVLPHAKVLRGLKKL
HHHHHHHHCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972