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The map label for this gene is ppsB

Identifier: 148662778

GI number: 148662778

Start: 3263064

End: 3267680

Strand: Direct

Name: ppsB

Synonym: MRA_2958

Alternate gene names: 148662778

Gene position: 3263064-3267680 (Clockwise)

Preceding gene: 148662777

Following gene: 148662779

Centisome position: 73.83

GC content: 65.37

Gene sequence:

>4617_bases
GTGATGCGAACGGCTTTCAGCCGGATTTCCGGTATGACCGCGCAACAGCGCACCTCCCTAGCCGACGAGTTCGACAGGGT
CTCTCGCATCGCCGTGGCCGAGCCGGTTGCGGTGGTTGGCATCGGCTGCCGCTTTCCGGGAGATGTGGATGGACCAGAGA
GTTTCTGGGACTTTCTGGTCGCGGGCAGGAATGCGATCTCGACGGTGCCGGCAGATCGATGGGACGCAGAAGCGTTTTAC
CACCCCGACCCGCTAACACCGGGGCGGATGACGACGAAGTGGGGCGGCTTCGTCCCTGACGTCGCGGGCTTCGACGCCGA
ATTCTTCGGTATCACACCGCGGGAAGCCGCGGCGATGGACCCGCAGCAGCGAATGCTGCTGGAGGTTGCCTGGGAAGCAC
TCGAACATGCCGGCATACCACCGGATTCCCTCGGCGGCACCCGAACCGCCGTCATGATGGGGGTCTATTTCAACGAGTAT
CAGTCCATGTTGGCCGCCAGTCCGCAGAACGTAGACGCCTACAGCGGGACCGGAAATGCACACAGCATCACGGTGGGTCG
CATCTCCTACCTGTTGGGATTACGGGGTCCGGCGGTCGCGGTGGACACCGCCTGCTCGTCGTCGTTGGTGGCTGTGCACC
TGGCGTGTCAGAGTCTGAGGCTGCGCGAGACCGATCTGGCTCTCGCCGGTGGAGTGAGTATCACCCTTCGCCCAGAGACC
CAAATCGCTATCTCTGCCTGGGGATTGCTGTCCCCGCAGGGCCGGTGTGCCGCATTCGATGCGGCGGCAGACGGATTTGT
GCGCGGTGAGGGCGCCGGAGTGGTAGTGCTCAAGCGGTTGACGGACGCGGTGCGCGACGGCGACCAGGTGCTGGCGGTGG
TGCGCGGTTCGGCAGTCAACCAGGACGGCAGGTCCAATGGCGTAACGGCGCCGAATACGGCAGCCCAGTGCGATGTGATC
GCCGATGCCTTGCGATCCGGCGATGTGGCGCCTGACAGCGTGAATTACGTAGAGGCCCATGGAACCGGCACGGTGCTGGG
CGACCCGATCGAATTCGAGGCCCTGGCCGCCACGTATGGCCACGGCGGGGACGCATGCGCGTTGGGTGCGGTGAAAACCA
ACATCGGTCATCTGGAGGCGGCCGCCGGGATCGCGGGGTTCATCAAGGCGACGCTGGCGGTACAACGCGCGACGATCCCG
CCGAATCTGCATTTCTCGCAATGGAATCCAGCTATCGATGCCGCGTCGACCAGGTTTTTCGTTCCCACGCAGAACTCCCC
GTGGCCAACCGCGGAGGGGCCGCGCCGGGCGGCGGTGTCGTCGTTCGGATTGGGCGGGACGAACGCACACGTGATCATCG
AGCAAGGTAGCGAGCTGGCTCCGGTATCCGAAGGCGGCGAGGACACCGGGGTGTCGACGTTGGTGGTGACGGGTAAGACG
GCCCAGCGGATGGCCGCGACGGCGCAGGTGCTGGCCGACTGGATGGAAGGTCCGGGCGCCGAGGTGGCCGTAGCTGATGT
CGCCCACACGGTCAACCATCACCGGGCCCGCCAAGCCACGTTCGGCACCGTCGTAGCCCGTGACCGCGCCCAGGCGATAG
CCGGACTGCGCGCGCTGGCCGCCGGCCAACACGCTCCCGGAGTGGTGAGCCACCAGGACGGTTCGCCGGGGCCGGGCACC
GTATTCGTCTACTCCGGCCGCGGCTCGCAGTGGGCCGGGATGGGTCGCCAATTGTTGGCCGACGAGCCGGCTTTCGCCGC
CGCGGTCGCCGAGCTGGAACCGGTGTTTGTCGAGCAAGCCGGCTTCTCGCTGCGCGACGTGATCGCCACCGGCAAGGAGC
TAGTCGGTATCGAGCAGATCCAGCTTGGCCTGATCGGCATGCAACTGACATTGACTGAGCTATGGCGCTCCTACGGGGTG
CAGCCCGACCTGGTGATCGGCCACTCCATGGGCGAGGTGGCCGCCGCCGTGGTCGCCGGAGCGCTGACTCCGGCCGAGGG
TCTGCGGGTGACCGCCACCCGCGCACGGTTGATGGCGCCATTGTCCGGCCAGGGCGGCATGGCACTGCTGGGACTCGATG
CTGCGGCCACCGAAGCGTTAATCGCGGACTACCCGCAGGTGACAGTGGGGATCTACAACTCGCCGCGGCAGACCGTGATC
GCCGGGCCGACCGAACAAATCGATGAGTTGATCGCCCGGGTGCGCGCGCAAAACCGGTTTGCCAGTCGGGTCAATATCGA
AGTCGCCCCGCACAATCCGGCCATGGATGCGCTGCAGCCGGCGATGCGTTCGGAGCTGGCCGATCTGACCCCACGGACCC
CCACCATCGGAATCATCTCCACCACCTACGCAGACTTGCACACCCAACCGATCTTCGACGCCGAACACTGGGCCACCAAC
ATGCGCAACCCCGTGCGCTTCCAGCAGGCCATCGCTTCCGCCGGTAGCGGCGCCGACGGCGCCTACCACACCTTCATCGA
GATCAGCGCACACCCGCTGCTGACCCAGGCGATTGCCGACACCTTGGAAGACGCGCACCGCCCAACCAAGTCCGCAGCGA
AATACTTGAGCATTGGCACCTTGCAGCGTGATGCCGATGACACGGTCACCTTCCGCACCAACCTCTACACCGCCGACATC
GCCCACCCACCGCATACCTGTCACCCGCCCGAGCCGCACCCCACCATCCCCACCACACCCTGGCAACACACCCACCACTG
GATCGCCACCACGCACCCGAGCACGGCAGCGCCAGAAGATCCGGGCAGCAATAAGGTTGTGGTGAACGGACAATCGACAT
CCGAGAGCCGTGCGCTCGAAGACTGGTGCCACCAGCTGGCCTGGCCGATCCGCCCGGCAGTCAGCGCCGACCCGCCCAGC
ACCGCCGCCTGGCTCGTGGTGGCAGACAACGAACTCTGCCACGAGCTGGCCCGTGCGGCCGATTCTCGGGTAGACAGCCT
CTCGCCGCCGGCGCTCGCAGCAGGCAGCGATCCGGCCGCACTGCTCGACGCGCTGCGCGGTGTGGACAACGTGCTCTACG
CTCCACCCGTCCCCGGTGAACTCCTCGATATTGAATCGGCCTACCAGGTTTTCCACGCAACGCGACGGCTAGCCGCCGCG
ATGGTCGCCAGCAGCGCCACGGCTATTTCCCCGCCGAAGTTGTTCATCATGACCCGCAACGCCCAGCCCATCTCGGAAGG
CGACCGAGCCAACCCTGGCCACGCTGTGCTGTGGGGTCTCGGCCGGTCGCTGGCACTAGAGCATCCTGAAATCTGGGGCG
GCATAATCGATCTCGACGATTCGATGCCCGCAGAGCTGGCCGTGCGGCATGTGCTGACTGCAGCCCACGGTACCGACGGG
GAGGATCAGGTCGTATACCGGTCGGGCGCACGCCATGTACCCCGGCTGCAGAGGCGAACTCTTCCGGGGAAACCGGTCAC
GTTGAATGCCGACGCCAGCCAGCTCGTCATCGGTGCGACCGGCAACATCGGACCGCATCTCATCCGACAGCTCGCGCGGA
TGGGGGCTAAGACAATCGTCGCGATGGCTCGCAAGCCCGGCGCGCTCGACGAGTTGACCCAATGTCTCGCTGCGACCGGA
ACAGATCTCATCGCGGTGGCCGCCGATGCGACCGATCCCGCCGCCATGCAAACCCTGTTCGACCGATTCGGCACGGAGCT
ACCGCCACTGGAGGGAATCTATCTGGCGGCCTTTGCGGGCCGCCCAGCGCTGCTGAGCGAGATGACCGACGACGACGTGA
CCACCATGTTTCGTCCCAAGTTGGACGCCTTGGCGTTGTTGCACCGACGGTCACTGAAGAGCCCAGTGCGCCACTTCGTT
TTGTTCTCTTCGGTGTCAGGTCTGCTGGGTTCTCGATGGCTCGCCCATTACACCGCGACCAGCGCCTTCCTGGACAGCTT
CGCCGGCGCGCGTCGCACCATGGGCCTGCCGGCCACCGTCGTCGACTGGGGACTGTGGAAGTCGCTGGCCGATGTGCAAA
AAGACGCGACTCAAATCAGCGCGGAATCCGGGCTGCAACCCATGGCTGACGAGGTGGCCATCGGCGCGCTACCGCTGGTG
ATGAACCCCGATGCGGCAGTCGCGACCGTGGTGGTTGCCGCGGACTGGCCCTTGTTGGCCGCGGCATATCGAACGCGGGG
AGCCCTTCGCATAGTCGACGACCTGTTGCCGGCACCGGAAGACGTCGGGAAGGGCGAAAGCGAATTCCGCACATCGTTGC
GTAGCTGCCCGGCGGAGAAACGACGGGACATGTTGTTCGACCATGTGGGCGCCTTGGCCGCCACGGTGATGGGAATGCCG
CCCACGGAGCCGCTCGATCCGTCGGCCGGCTTCTTCCAACTCGGCATGGACTCGCTAATGAGCGTGACACTTCAGCGGGC
GTTGTCGGAAAGCCTGGGCGAGTTCTTGCCGGCGTCCGTGGTTTTCGACTATCCGACCGTTTACAGCCTCACCGACTACC
TGGCCACCGTCCTGCCTGAGCTCCTCGAAATTGGGGCAACCGCAGTCGCAACCCAGCAAGCCACCGACTCCTACCACGAA
CTGACCGAAGCCGAGTTGTTGGAACAACTTTCGGAACGACTAAGAGGAACACAATGA

Upstream 100 bases:

>100_bases
AAGACAACCAGATTTCCGCGCTATCCTCGTCGGCCGGAAGTGTGTTGGACAGTCTATTCGATCGCATCGAATCGGCGCCG
CCTGAGGCCGAGAGGTCGGT

Downstream 100 bases:

>100_bases
CCGCAGCGACACCAGATCGCCGAGCGATCATCACCGAGGCGCTGCACAAGATCGATGATCTCACGGCGCGCCTGGAAATC
GCCGAAAAATCCAGCAGCGA

Product: phenolpthiocerol synthesis type-I polyketide synthase PpsB

Products: [acyl carrier protein]; acetoacetyl-ACP; CO2; [acyl carrier protein]; beta-ketoacyl-ACP [C]

Alternate protein names: NA

Number of amino acids: Translated: 1538; Mature: 1538

Protein sequence:

>1538_residues
MMRTAFSRISGMTAQQRTSLADEFDRVSRIAVAEPVAVVGIGCRFPGDVDGPESFWDFLVAGRNAISTVPADRWDAEAFY
HPDPLTPGRMTTKWGGFVPDVAGFDAEFFGITPREAAAMDPQQRMLLEVAWEALEHAGIPPDSLGGTRTAVMMGVYFNEY
QSMLAASPQNVDAYSGTGNAHSITVGRISYLLGLRGPAVAVDTACSSSLVAVHLACQSLRLRETDLALAGGVSITLRPET
QIAISAWGLLSPQGRCAAFDAAADGFVRGEGAGVVVLKRLTDAVRDGDQVLAVVRGSAVNQDGRSNGVTAPNTAAQCDVI
ADALRSGDVAPDSVNYVEAHGTGTVLGDPIEFEALAATYGHGGDACALGAVKTNIGHLEAAAGIAGFIKATLAVQRATIP
PNLHFSQWNPAIDAASTRFFVPTQNSPWPTAEGPRRAAVSSFGLGGTNAHVIIEQGSELAPVSEGGEDTGVSTLVVTGKT
AQRMAATAQVLADWMEGPGAEVAVADVAHTVNHHRARQATFGTVVARDRAQAIAGLRALAAGQHAPGVVSHQDGSPGPGT
VFVYSGRGSQWAGMGRQLLADEPAFAAAVAELEPVFVEQAGFSLRDVIATGKELVGIEQIQLGLIGMQLTLTELWRSYGV
QPDLVIGHSMGEVAAAVVAGALTPAEGLRVTATRARLMAPLSGQGGMALLGLDAAATEALIADYPQVTVGIYNSPRQTVI
AGPTEQIDELIARVRAQNRFASRVNIEVAPHNPAMDALQPAMRSELADLTPRTPTIGIISTTYADLHTQPIFDAEHWATN
MRNPVRFQQAIASAGSGADGAYHTFIEISAHPLLTQAIADTLEDAHRPTKSAAKYLSIGTLQRDADDTVTFRTNLYTADI
AHPPHTCHPPEPHPTIPTTPWQHTHHWIATTHPSTAAPEDPGSNKVVVNGQSTSESRALEDWCHQLAWPIRPAVSADPPS
TAAWLVVADNELCHELARAADSRVDSLSPPALAAGSDPAALLDALRGVDNVLYAPPVPGELLDIESAYQVFHATRRLAAA
MVASSATAISPPKLFIMTRNAQPISEGDRANPGHAVLWGLGRSLALEHPEIWGGIIDLDDSMPAELAVRHVLTAAHGTDG
EDQVVYRSGARHVPRLQRRTLPGKPVTLNADASQLVIGATGNIGPHLIRQLARMGAKTIVAMARKPGALDELTQCLAATG
TDLIAVAADATDPAAMQTLFDRFGTELPPLEGIYLAAFAGRPALLSEMTDDDVTTMFRPKLDALALLHRRSLKSPVRHFV
LFSSVSGLLGSRWLAHYTATSAFLDSFAGARRTMGLPATVVDWGLWKSLADVQKDATQISAESGLQPMADEVAIGALPLV
MNPDAAVATVVVAADWPLLAAAYRTRGALRIVDDLLPAPEDVGKGESEFRTSLRSCPAEKRRDMLFDHVGALAATVMGMP
PTEPLDPSAGFFQLGMDSLMSVTLQRALSESLGEFLPASVVFDYPTVYSLTDYLATVLPELLEIGATAVATQQATDSYHE
LTEAELLEQLSERLRGTQ

Sequences:

>Translated_1538_residues
MMRTAFSRISGMTAQQRTSLADEFDRVSRIAVAEPVAVVGIGCRFPGDVDGPESFWDFLVAGRNAISTVPADRWDAEAFY
HPDPLTPGRMTTKWGGFVPDVAGFDAEFFGITPREAAAMDPQQRMLLEVAWEALEHAGIPPDSLGGTRTAVMMGVYFNEY
QSMLAASPQNVDAYSGTGNAHSITVGRISYLLGLRGPAVAVDTACSSSLVAVHLACQSLRLRETDLALAGGVSITLRPET
QIAISAWGLLSPQGRCAAFDAAADGFVRGEGAGVVVLKRLTDAVRDGDQVLAVVRGSAVNQDGRSNGVTAPNTAAQCDVI
ADALRSGDVAPDSVNYVEAHGTGTVLGDPIEFEALAATYGHGGDACALGAVKTNIGHLEAAAGIAGFIKATLAVQRATIP
PNLHFSQWNPAIDAASTRFFVPTQNSPWPTAEGPRRAAVSSFGLGGTNAHVIIEQGSELAPVSEGGEDTGVSTLVVTGKT
AQRMAATAQVLADWMEGPGAEVAVADVAHTVNHHRARQATFGTVVARDRAQAIAGLRALAAGQHAPGVVSHQDGSPGPGT
VFVYSGRGSQWAGMGRQLLADEPAFAAAVAELEPVFVEQAGFSLRDVIATGKELVGIEQIQLGLIGMQLTLTELWRSYGV
QPDLVIGHSMGEVAAAVVAGALTPAEGLRVTATRARLMAPLSGQGGMALLGLDAAATEALIADYPQVTVGIYNSPRQTVI
AGPTEQIDELIARVRAQNRFASRVNIEVAPHNPAMDALQPAMRSELADLTPRTPTIGIISTTYADLHTQPIFDAEHWATN
MRNPVRFQQAIASAGSGADGAYHTFIEISAHPLLTQAIADTLEDAHRPTKSAAKYLSIGTLQRDADDTVTFRTNLYTADI
AHPPHTCHPPEPHPTIPTTPWQHTHHWIATTHPSTAAPEDPGSNKVVVNGQSTSESRALEDWCHQLAWPIRPAVSADPPS
TAAWLVVADNELCHELARAADSRVDSLSPPALAAGSDPAALLDALRGVDNVLYAPPVPGELLDIESAYQVFHATRRLAAA
MVASSATAISPPKLFIMTRNAQPISEGDRANPGHAVLWGLGRSLALEHPEIWGGIIDLDDSMPAELAVRHVLTAAHGTDG
EDQVVYRSGARHVPRLQRRTLPGKPVTLNADASQLVIGATGNIGPHLIRQLARMGAKTIVAMARKPGALDELTQCLAATG
TDLIAVAADATDPAAMQTLFDRFGTELPPLEGIYLAAFAGRPALLSEMTDDDVTTMFRPKLDALALLHRRSLKSPVRHFV
LFSSVSGLLGSRWLAHYTATSAFLDSFAGARRTMGLPATVVDWGLWKSLADVQKDATQISAESGLQPMADEVAIGALPLV
MNPDAAVATVVVAADWPLLAAAYRTRGALRIVDDLLPAPEDVGKGESEFRTSLRSCPAEKRRDMLFDHVGALAATVMGMP
PTEPLDPSAGFFQLGMDSLMSVTLQRALSESLGEFLPASVVFDYPTVYSLTDYLATVLPELLEIGATAVATQQATDSYHE
LTEAELLEQLSERLRGTQ
>Mature_1538_residues
MMRTAFSRISGMTAQQRTSLADEFDRVSRIAVAEPVAVVGIGCRFPGDVDGPESFWDFLVAGRNAISTVPADRWDAEAFY
HPDPLTPGRMTTKWGGFVPDVAGFDAEFFGITPREAAAMDPQQRMLLEVAWEALEHAGIPPDSLGGTRTAVMMGVYFNEY
QSMLAASPQNVDAYSGTGNAHSITVGRISYLLGLRGPAVAVDTACSSSLVAVHLACQSLRLRETDLALAGGVSITLRPET
QIAISAWGLLSPQGRCAAFDAAADGFVRGEGAGVVVLKRLTDAVRDGDQVLAVVRGSAVNQDGRSNGVTAPNTAAQCDVI
ADALRSGDVAPDSVNYVEAHGTGTVLGDPIEFEALAATYGHGGDACALGAVKTNIGHLEAAAGIAGFIKATLAVQRATIP
PNLHFSQWNPAIDAASTRFFVPTQNSPWPTAEGPRRAAVSSFGLGGTNAHVIIEQGSELAPVSEGGEDTGVSTLVVTGKT
AQRMAATAQVLADWMEGPGAEVAVADVAHTVNHHRARQATFGTVVARDRAQAIAGLRALAAGQHAPGVVSHQDGSPGPGT
VFVYSGRGSQWAGMGRQLLADEPAFAAAVAELEPVFVEQAGFSLRDVIATGKELVGIEQIQLGLIGMQLTLTELWRSYGV
QPDLVIGHSMGEVAAAVVAGALTPAEGLRVTATRARLMAPLSGQGGMALLGLDAAATEALIADYPQVTVGIYNSPRQTVI
AGPTEQIDELIARVRAQNRFASRVNIEVAPHNPAMDALQPAMRSELADLTPRTPTIGIISTTYADLHTQPIFDAEHWATN
MRNPVRFQQAIASAGSGADGAYHTFIEISAHPLLTQAIADTLEDAHRPTKSAAKYLSIGTLQRDADDTVTFRTNLYTADI
AHPPHTCHPPEPHPTIPTTPWQHTHHWIATTHPSTAAPEDPGSNKVVVNGQSTSESRALEDWCHQLAWPIRPAVSADPPS
TAAWLVVADNELCHELARAADSRVDSLSPPALAAGSDPAALLDALRGVDNVLYAPPVPGELLDIESAYQVFHATRRLAAA
MVASSATAISPPKLFIMTRNAQPISEGDRANPGHAVLWGLGRSLALEHPEIWGGIIDLDDSMPAELAVRHVLTAAHGTDG
EDQVVYRSGARHVPRLQRRTLPGKPVTLNADASQLVIGATGNIGPHLIRQLARMGAKTIVAMARKPGALDELTQCLAATG
TDLIAVAADATDPAAMQTLFDRFGTELPPLEGIYLAAFAGRPALLSEMTDDDVTTMFRPKLDALALLHRRSLKSPVRHFV
LFSSVSGLLGSRWLAHYTATSAFLDSFAGARRTMGLPATVVDWGLWKSLADVQKDATQISAESGLQPMADEVAIGALPLV
MNPDAAVATVVVAADWPLLAAAYRTRGALRIVDDLLPAPEDVGKGESEFRTSLRSCPAEKRRDMLFDHVGALAATVMGMP
PTEPLDPSAGFFQLGMDSLMSVTLQRALSESLGEFLPASVVFDYPTVYSLTDYLATVLPELLEIGATAVATQQATDSYHE
LTEAELLEQLSERLRGTQ

Specific function: Polyketide synthase involved in phenolpthiocerol synthesis

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 acyl carrier domain

Homologues:

Organism=Homo sapiens, GI41872631, Length=924, Percent_Identity=29.978354978355, Blast_Score=331, Evalue=4e-90,
Organism=Homo sapiens, GI8923559, Length=459, Percent_Identity=28.1045751633987, Blast_Score=122, Evalue=2e-27,
Organism=Homo sapiens, GI310129082, Length=108, Percent_Identity=34.2592592592593, Blast_Score=78, Evalue=7e-14,
Organism=Homo sapiens, GI310109937, Length=108, Percent_Identity=34.2592592592593, Blast_Score=78, Evalue=7e-14,
Organism=Homo sapiens, GI239744023, Length=108, Percent_Identity=34.2592592592593, Blast_Score=78, Evalue=8e-14,
Organism=Homo sapiens, GI223972627, Length=155, Percent_Identity=33.5483870967742, Blast_Score=70, Evalue=1e-11,
Organism=Escherichia coli, GI1787337, Length=438, Percent_Identity=26.7123287671233, Blast_Score=122, Evalue=1e-28,
Organism=Escherichia coli, GI1788663, Length=268, Percent_Identity=26.865671641791, Blast_Score=82, Evalue=2e-16,
Organism=Escherichia coli, GI1787334, Length=297, Percent_Identity=28.6195286195286, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI212642053, Length=919, Percent_Identity=29.0533188248096, Blast_Score=333, Evalue=3e-91,
Organism=Caenorhabditis elegans, GI17550940, Length=436, Percent_Identity=33.0275229357798, Blast_Score=229, Evalue=6e-60,
Organism=Caenorhabditis elegans, GI71983541, Length=283, Percent_Identity=28.6219081272085, Blast_Score=104, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI71983535, Length=270, Percent_Identity=29.6296296296296, Blast_Score=101, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6320904, Length=447, Percent_Identity=24.6085011185682, Blast_Score=96, Evalue=5e-20,
Organism=Drosophila melanogaster, GI221330659, Length=907, Percent_Identity=29.6582138919515, Blast_Score=325, Evalue=1e-88,
Organism=Drosophila melanogaster, GI19920632, Length=907, Percent_Identity=29.6582138919515, Blast_Score=325, Evalue=2e-88,
Organism=Drosophila melanogaster, GI24581345, Length=906, Percent_Identity=29.1390728476821, Blast_Score=311, Evalue=2e-84,
Organism=Drosophila melanogaster, GI24644341, Length=443, Percent_Identity=27.0880361173815, Blast_Score=113, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PPSB_MYCTU (Q10978)

Other databases:

- EMBL:   BX842581
- EMBL:   AE000516
- PIR:   E70874
- RefSeq:   NP_217448.1
- RefSeq:   NP_337515.1
- ProteinModelPortal:   Q10978
- EnsemblBacteria:   EBMYCT00000000095
- EnsemblBacteria:   EBMYCT00000069981
- GeneID:   888023
- GeneID:   925274
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT3002
- KEGG:   mtu:Rv2932
- TIGR:   MT3002
- TubercuList:   Rv2932
- GeneTree:   EBGT00070000032290
- HOGENOM:   HBG669988
- OMA:   VAMFRPK
- ProtClustDB:   CLSK792170
- InterPro:   IPR001227
- InterPro:   IPR009081
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016036
- InterPro:   IPR016040
- InterPro:   IPR006163
- InterPro:   IPR020801
- InterPro:   IPR020841
- InterPro:   IPR013968
- InterPro:   IPR020806
- InterPro:   IPR016039
- InterPro:   IPR016038
- Gene3D:   G3DSA:3.40.366.10
- Gene3D:   G3DSA:1.10.1200.10
- Gene3D:   G3DSA:3.40.50.720
- Gene3D:   G3DSA:3.40.47.10
- PANTHER:   PTHR11712
- SMART:   SM00827
- SMART:   SM00825
- SMART:   SM00823

Pfam domain/function: PF00698 Acyl_transf_1; PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C; PF08659 KR; PF00550 PP-binding; SSF47336 ACP_like; SSF52151 Acyl_Trfase/lysoPlipase; SSF55048 Malonyl_transacylase_ACP-bd; SSF53901 Thiolase-like

EC number: 2.3.1.41 [C]

Molecular weight: Translated: 162529; Mature: 162529

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: PS50075 ACP_DOMAIN; PS00606 B_KETOACYL_SYNTHASE; PS00012 PHOSPHOPANTETHEINE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMRTAFSRISGMTAQQRTSLADEFDRVSRIAVAEPVAVVGIGCRFPGDVDGPESFWDFLV
CCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHH
AGRNAISTVPADRWDAEAFYHPDPLTPGRMTTKWGGFVPDVAGFDAEFFGITPREAAAMD
HCCCHHCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCHHHCCC
PQQRMLLEVAWEALEHAGIPPDSLGGTRTAVMMGVYFNEYQSMLAASPQNVDAYSGTGNA
HHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
HSITVGRISYLLGLRGPAVAVDTACSSSLVAVHLACQSLRLRETDLALAGGVSITLRPET
CEEEHHHHHHHHHCCCCCEEEEHHCCCHHHHHHHHHHHHHCCHHCEEEECCEEEEECCCC
QIAISAWGLLSPQGRCAAFDAAADGFVRGEGAGVVVLKRLTDAVRDGDQVLAVVRGSAVN
EEEEEECCCCCCCCCEEEECCCCCCCEECCCCCEEHHHHHHHHHHCCCCEEEEEECCCCC
QDGRSNGVTAPNTAAQCDVIADALRSGDVAPDSVNYVEAHGTGTVLGDPIEFEALAATYG
CCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCEECCCCCHHHHHHHCC
HGGDACALGAVKTNIGHLEAAAGIAGFIKATLAVQRATIPPNLHFSQWNPAIDAASTRFF
CCCCEEEECHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEE
VPTQNSPWPTAEGPRRAAVSSFGLGGTNAHVIIEQGSELAPVSEGGEDTGVSTLVVTGKT
EECCCCCCCCCCCCHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCCCEEEEEECCH
AQRMAATAQVLADWMEGPGAEVAVADVAHTVNHHRARQATFGTVVARDRAQAIAGLRALA
HHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGQHAPGVVSHQDGSPGPGTVFVYSGRGSQWAGMGRQLLADEPAFAAAVAELEPVFVEQA
CCCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHCCHHHHCCCCHHHHHHHHHCHHHHHHC
GFSLRDVIATGKELVGIEQIQLGLIGMQLTLTELWRSYGVQPDLVIGHSMGEVAAAVVAG
CCHHHHHHHCCHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHH
ALTPAEGLRVTATRARLMAPLSGQGGMALLGLDAAATEALIADYPQVTVGIYNSPRQTVI
CCCCCCCCEEEEEHHHHCCCCCCCCCEEEEECCHHHHHHHHHCCCCEEEEEECCCCCEEE
AGPTEQIDELIARVRAQNRFASRVNIEVAPHNPAMDALQPAMRSELADLTPRTPTIGIIS
ECCHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEE
TTYADLHTQPIFDAEHWATNMRNPVRFQQAIASAGSGADGAYHTFIEISAHPLLTQAIAD
ECHHHHCCCCCCCHHHHHHCCCCHHHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHH
TLEDAHRPTKSAAKYLSIGTLQRDADDTVTFRTNLYTADIAHPPHTCHPPEPHPTIPTTP
HHHHHCCCHHHHHHHHHHHCCCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCCCCCCCCC
WQHTHHWIATTHPSTAAPEDPGSNKVVVNGQSTSESRALEDWCHQLAWPIRPAVSADPPS
CCCCCCEEEECCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCC
TAAWLVVADNELCHELARAADSRVDSLSPPALAAGSDPAALLDALRGVDNVLYAPPVPGE
CEEEEEEECHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCEEECCCCCCH
LLDIESAYQVFHATRRLAAAMVASSATAISPPKLFIMTRNAQPISEGDRANPGHAVLWGL
HCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCEEEEEC
GRSLALEHPEIWGGIIDLDDSMPAELAVRHVLTAAHGTDGEDQVVYRSGARHVPRLQRRT
CCHHCCCCHHHCCCEEECCCCCCHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHC
LPGKPVTLNADASQLVIGATGNIGPHLIRQLARMGAKTIVAMARKPGALDELTQCLAATG
CCCCCEEECCCCCEEEEECCCCCCHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHCC
TDLIAVAADATDPAAMQTLFDRFGTELPPLEGIYLAAFAGRPALLSEMTDDDVTTMFRPK
CCEEEEEECCCCHHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHCCCCCHHHHHCCC
LDALALLHRRSLKSPVRHFVLFSSVSGLLGSRWLAHYTATSAFLDSFAGARRTMGLPATV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
VDWGLWKSLADVQKDATQISAESGLQPMADEVAIGALPLVMNPDAAVATVVVAADWPLLA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCEEEEECCCHHHEEEEEECCCHHHH
AAYRTRGALRIVDDLLPAPEDVGKGESEFRTSLRSCPAEKRRDMLFDHVGALAATVMGMP
HHHHHCCHHHHHHHHCCCCHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCC
PTEPLDPSAGFFQLGMDSLMSVTLQRALSESLGEFLPASVVFDYPTVYSLTDYLATVLPE
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEECCCHHHHHHHHHHHHHHH
LLEIGATAVATQQATDSYHELTEAELLEQLSERLRGTQ
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MMRTAFSRISGMTAQQRTSLADEFDRVSRIAVAEPVAVVGIGCRFPGDVDGPESFWDFLV
CCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHH
AGRNAISTVPADRWDAEAFYHPDPLTPGRMTTKWGGFVPDVAGFDAEFFGITPREAAAMD
HCCCHHCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCHHHCCC
PQQRMLLEVAWEALEHAGIPPDSLGGTRTAVMMGVYFNEYQSMLAASPQNVDAYSGTGNA
HHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
HSITVGRISYLLGLRGPAVAVDTACSSSLVAVHLACQSLRLRETDLALAGGVSITLRPET
CEEEHHHHHHHHHCCCCCEEEEHHCCCHHHHHHHHHHHHHCCHHCEEEECCEEEEECCCC
QIAISAWGLLSPQGRCAAFDAAADGFVRGEGAGVVVLKRLTDAVRDGDQVLAVVRGSAVN
EEEEEECCCCCCCCCEEEECCCCCCCEECCCCCEEHHHHHHHHHHCCCCEEEEEECCCCC
QDGRSNGVTAPNTAAQCDVIADALRSGDVAPDSVNYVEAHGTGTVLGDPIEFEALAATYG
CCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCEECCCCCHHHHHHHCC
HGGDACALGAVKTNIGHLEAAAGIAGFIKATLAVQRATIPPNLHFSQWNPAIDAASTRFF
CCCCEEEECHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEE
VPTQNSPWPTAEGPRRAAVSSFGLGGTNAHVIIEQGSELAPVSEGGEDTGVSTLVVTGKT
EECCCCCCCCCCCCHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCCCEEEEEECCH
AQRMAATAQVLADWMEGPGAEVAVADVAHTVNHHRARQATFGTVVARDRAQAIAGLRALA
HHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGQHAPGVVSHQDGSPGPGTVFVYSGRGSQWAGMGRQLLADEPAFAAAVAELEPVFVEQA
CCCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHCCHHHHCCCCHHHHHHHHHCHHHHHHC
GFSLRDVIATGKELVGIEQIQLGLIGMQLTLTELWRSYGVQPDLVIGHSMGEVAAAVVAG
CCHHHHHHHCCHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHH
ALTPAEGLRVTATRARLMAPLSGQGGMALLGLDAAATEALIADYPQVTVGIYNSPRQTVI
CCCCCCCCEEEEEHHHHCCCCCCCCCEEEEECCHHHHHHHHHCCCCEEEEEECCCCCEEE
AGPTEQIDELIARVRAQNRFASRVNIEVAPHNPAMDALQPAMRSELADLTPRTPTIGIIS
ECCHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEE
TTYADLHTQPIFDAEHWATNMRNPVRFQQAIASAGSGADGAYHTFIEISAHPLLTQAIAD
ECHHHHCCCCCCCHHHHHHCCCCHHHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHH
TLEDAHRPTKSAAKYLSIGTLQRDADDTVTFRTNLYTADIAHPPHTCHPPEPHPTIPTTP
HHHHHCCCHHHHHHHHHHHCCCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCCCCCCCCC
WQHTHHWIATTHPSTAAPEDPGSNKVVVNGQSTSESRALEDWCHQLAWPIRPAVSADPPS
CCCCCCEEEECCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCC
TAAWLVVADNELCHELARAADSRVDSLSPPALAAGSDPAALLDALRGVDNVLYAPPVPGE
CEEEEEEECHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCEEECCCCCCH
LLDIESAYQVFHATRRLAAAMVASSATAISPPKLFIMTRNAQPISEGDRANPGHAVLWGL
HCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCEEEEEC
GRSLALEHPEIWGGIIDLDDSMPAELAVRHVLTAAHGTDGEDQVVYRSGARHVPRLQRRT
CCHHCCCCHHHCCCEEECCCCCCHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHC
LPGKPVTLNADASQLVIGATGNIGPHLIRQLARMGAKTIVAMARKPGALDELTQCLAATG
CCCCCEEECCCCCEEEEECCCCCCHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHCC
TDLIAVAADATDPAAMQTLFDRFGTELPPLEGIYLAAFAGRPALLSEMTDDDVTTMFRPK
CCEEEEEECCCCHHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHCCCCCHHHHHCCC
LDALALLHRRSLKSPVRHFVLFSSVSGLLGSRWLAHYTATSAFLDSFAGARRTMGLPATV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
VDWGLWKSLADVQKDATQISAESGLQPMADEVAIGALPLVMNPDAAVATVVVAADWPLLA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCEEEEECCCHHHEEEEEECCCHHHH
AAYRTRGALRIVDDLLPAPEDVGKGESEFRTSLRSCPAEKRRDMLFDHVGALAATVMGMP
HHHHHCCHHHHHHHHCCCCHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCC
PTEPLDPSAGFFQLGMDSLMSVTLQRALSESLGEFLPASVVFDYPTVYSLTDYLATVLPE
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEECCCHHHHHHHHHHHHHHH
LLEIGATAVATQQATDSYHELTEAELLEQLSERLRGTQ
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: None [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 0.04 {acetyl-ACP}} 0.031 {acetyl-ACP}} 0.138 {cis-9-hexadecenoyl-ACP}} 0.017 {cis-9-hexadecenoyl-ACP}} 0.012 {cis-3-decenoyl-ACP}} [C]

Substrates: acetyl-ACP; malonyl-ACP; acyl-ACP [C]

Specific reaction: acetyl-ACP + malonyl-ACP = [acyl carrier protein] + acetoacetyl-ACP + CO2 acyl-ACP + malonyl-ACP = [acyl carrier protein] + beta-ketoacyl-ACP + CO2 [C]

General reaction: Acyl group transfer [C]

Inhibitor: Acetyl-CoA; Acyl-CoA; Iodoacetamide; N-Ethyl maleimide acyl -ACP-derivatives protect, malonyl-ACP-decarboxylation, Cerulenin [C]

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036