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The map label for this gene is PE_PGRS46

Identifier: 148662475

GI number: 148662475

Start: 2972073

End: 2974373

Strand: Reverse

Name: PE_PGRS46

Synonym: MRA_2663

Alternate gene names: 148662475

Gene position: 2974373-2972073 (Counterclockwise)

Preceding gene: 148662480

Following gene: 148662474

Centisome position: 67.29

GC content: 74.79

Gene sequence:

>2301_bases
ATGGCGGCTTCGGATCTGGCCAACATTGGGTCGACGATCAACGCGGCGAATGCGGCGGCGGCATTGCCGACCACGGGGGT
GGTGGCGGCTGCCGCGGATGAGGTTTCGGCGGCAGTTGCGGCCTTGTTCGGGTCGTACGCGCAGAGCTATCAGGCTTTTG
GTGCGCAGCTGTCGGCGTTTCACGCCCAGTTCGTGCAGTCCCTTACGAACGGCGCGCGCTCATACGTAGTTGCCGAGGCC
ACCAGTGCTGCGCCGTTGCAGGATTTGTTGGGCGTGGTAAATGCCCCCGCCCAGGCGTTGTTGGGGCGCCCGTTGATCGG
CAATGGCGCTAACGGGGCCGACGGGACGGGGGCTCCCGGTGGGCCGGGCGGGCTGTTGCTTGGCAACGGCGGGAATGGCG
GATCGGGTGCGCCGGGTCAGCCAGGTGGTGCTGGCGGGGATGCGGGGTTGATCGGTAACGGCGGGACTGGCGGTAAAGGT
GGGGACGGGCTGGTCGGGTCCGGTGCTGCCGGGGGTGTCGGTGGTCGCGGTGGATGGTTGCTGGGTAATGGCGGGACCGG
TGGGGCTGGTGGGGCTGCAGGGGCCACTTTGGTCGGCGGTACTGGCGGTGTCGGTGGGGCGACGGGGTTGATCGGCAGCG
GGGGCTTCGGCGGTGCTGGCGGGGCCGCGGCGGGGGTGGGCACCACCGGCGGCGTGGGCGGGAGCGGTGGCGTTGGCGGC
GTGTTCGGCAATGGTGGATTCGGCGGGGCCGGTGGCCTTGGCGCCGCCGGCGGCGTCGGAGGGGCGGCCAGCTACTTCGG
GACCGGGGGCGGTGGCGGCGTTGGTGGGGACGGTGCGCCCGGTGGTGACGGCGGTGCGGGTCCGCTATTGATCGGCAATG
GCGGTGTTGGGGGTCTGGGTGGGGCCGGGGCGGCCGGTGGTAATGGCGGTGCCGGCGGGATGTTGTTGGGCGATGGCGGT
GCCGGCGGACAGGGTGGGCCGGCCGTGGCGGGTGTCCTGGGCGGGATGCCCGGCGCGGGCGGCAACGGCGGTAATGCCAA
CTGGTTCGGGTCCGGTGGTGCCGGCGGGCAGGGTGGCACCGGTCTGGCCGGGACAAACGGGGTCAACCCCGGCTCGATTG
CGAACCCCAACACCGGTGCGAACGGTACCGACAACAGCGGCAACGGGAATCAAACTGGCGGGAACGGGGGTCCCGGCCCC
GCCGGTGGCGTCGGCGAGGCTGGCGGCGTCGGCGGGCAGGGCGGGCTGGGGGAGTCGCTCGACGGCAACGACGGCACCGG
CGGTAAGGGTGGAGCCGGGGGTACTGCCGGTACCGATGGCGGTGCCGGCGGCGCTGGCGGCGCTGGCGGCATAGGTGAGA
CCGACGGCAGCGCCGGCGGCGTGGCTACCGGGGGTGAGGGGGGTGACGGTGCCACCGGAGGGGTCGACGGTGGCGTGGGT
GGTGCTGGCGGCAAGGGGGGGCAGGGGCACAACACGGGTGTAGGTGACGCTTTCGGCGGTGACGGCGGAATCGGCGGTGA
CGGTAACGGGGCACTAGGCGCGGCGGGCGGTAACGGCGGCACCGGTGGTGCCGGTGGAAACGGTGGACGTGGCGGGATGT
TAATCGGCAACGGCGGCGCCGGTGGGGCCGGCGGGACGGGCGGCACCGGTGGTGGTGGCGCCGCCGGCTTCGCGGGCGGT
GTCGGCGGCGCGGGCGGAGAGGGTCTCACCGACGGTGCGGGTACCGCGGAAGGCGGCACCGGCGGTCTGGGGGGCCTCGG
CGGTGTCGGCGGTACCGGCGGTATGGGTGGCAGCGGCGGTGTCGGCGGCAACGGCGGGGCGGCTGGGTCGCTCATCGGGC
TTGGTGGTGGCGGGGGTGCCGGCGGTGTCGGCGGCACCGGTGGCATCGGCGGCATCGGTGGTGCCGGCGGCAACGGTGGC
GCCGGCGGCGCGGGTACCACCACCGGCGGGGGAGCGACAATTGGCGGTGGCGGCGGTACAGGCGGCGTGGGGGGCGCTGG
TGGCACTGGCGGTACCGGCGGCGCCGGCGGGACCACCGGCGGCAGCGGCGGAGCCGGCGGGCTGATCGGGTGGGCAGGAG
CTGCCGGCGGCACCGGCGCAGGCGGCACGGGTGGGCAAGGTGGCCTCGGCGGCCAGGGCGGCAACGGCGGCAACGGCGGG
ACCGGCGCGACCGGCGGTCAGGGCGGCGATTTCGCGCTGGGCGGCAACGGGGGCGCCGGCGGCGCGGGTGGGTCACCGGG
TGGCAGCTCCGGCATCCAGGGCAATATGGGCCCGCCCGGCACCCAGGGCGCCGACGGATAG

Upstream 100 bases:

>100_bases
GTTGCTGCCGAGTGCTCGATGATCCGCGGCGACCATGCGGGTTGTCCGGTCCAGGAGGTCGCAGATGTCATTTGTGATTG
CGGTGCCGGAAGCATTGACG

Downstream 100 bases:

>100_bases
TTGTTGCCGTTAGGCGCGAACATCACGCTCGCCGAACTGCCCGAACCCGAACTGCGGCAACTGTTTCCGCACGAGGAGCT
GCAGATCCCGGTATCCTGCG

Product: PE-PGRS family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 766; Mature: 765

Protein sequence:

>766_residues
MAASDLANIGSTINAANAAAALPTTGVVAAAADEVSAAVAALFGSYAQSYQAFGAQLSAFHAQFVQSLTNGARSYVVAEA
TSAAPLQDLLGVVNAPAQALLGRPLIGNGANGADGTGAPGGPGGLLLGNGGNGGSGAPGQPGGAGGDAGLIGNGGTGGKG
GDGLVGSGAAGGVGGRGGWLLGNGGTGGAGGAAGATLVGGTGGVGGATGLIGSGGFGGAGGAAAGVGTTGGVGGSGGVGG
VFGNGGFGGAGGLGAAGGVGGAASYFGTGGGGGVGGDGAPGGDGGAGPLLIGNGGVGGLGGAGAAGGNGGAGGMLLGDGG
AGGQGGPAVAGVLGGMPGAGGNGGNANWFGSGGAGGQGGTGLAGTNGVNPGSIANPNTGANGTDNSGNGNQTGGNGGPGP
AGGVGEAGGVGGQGGLGESLDGNDGTGGKGGAGGTAGTDGGAGGAGGAGGIGETDGSAGGVATGGEGGDGATGGVDGGVG
GAGGKGGQGHNTGVGDAFGGDGGIGGDGNGALGAAGGNGGTGGAGGNGGRGGMLIGNGGAGGAGGTGGTGGGGAAGFAGG
VGGAGGEGLTDGAGTAEGGTGGLGGLGGVGGTGGMGGSGGVGGNGGAAGSLIGLGGGGGAGGVGGTGGIGGIGGAGGNGG
AGGAGTTTGGGATIGGGGGTGGVGGAGGTGGTGGAGGTTGGSGGAGGLIGWAGAAGGTGAGGTGGQGGLGGQGGNGGNGG
TGATGGQGGDFALGGNGGAGGAGGSPGGSSGIQGNMGPPGTQGADG

Sequences:

>Translated_766_residues
MAASDLANIGSTINAANAAAALPTTGVVAAAADEVSAAVAALFGSYAQSYQAFGAQLSAFHAQFVQSLTNGARSYVVAEA
TSAAPLQDLLGVVNAPAQALLGRPLIGNGANGADGTGAPGGPGGLLLGNGGNGGSGAPGQPGGAGGDAGLIGNGGTGGKG
GDGLVGSGAAGGVGGRGGWLLGNGGTGGAGGAAGATLVGGTGGVGGATGLIGSGGFGGAGGAAAGVGTTGGVGGSGGVGG
VFGNGGFGGAGGLGAAGGVGGAASYFGTGGGGGVGGDGAPGGDGGAGPLLIGNGGVGGLGGAGAAGGNGGAGGMLLGDGG
AGGQGGPAVAGVLGGMPGAGGNGGNANWFGSGGAGGQGGTGLAGTNGVNPGSIANPNTGANGTDNSGNGNQTGGNGGPGP
AGGVGEAGGVGGQGGLGESLDGNDGTGGKGGAGGTAGTDGGAGGAGGAGGIGETDGSAGGVATGGEGGDGATGGVDGGVG
GAGGKGGQGHNTGVGDAFGGDGGIGGDGNGALGAAGGNGGTGGAGGNGGRGGMLIGNGGAGGAGGTGGTGGGGAAGFAGG
VGGAGGEGLTDGAGTAEGGTGGLGGLGGVGGTGGMGGSGGVGGNGGAAGSLIGLGGGGGAGGVGGTGGIGGIGGAGGNGG
AGGAGTTTGGGATIGGGGGTGGVGGAGGTGGTGGAGGTTGGSGGAGGLIGWAGAAGGTGAGGTGGQGGLGGQGGNGGNGG
TGATGGQGGDFALGGNGGAGGAGGSPGGSSGIQGNMGPPGTQGADG
>Mature_765_residues
AASDLANIGSTINAANAAAALPTTGVVAAAADEVSAAVAALFGSYAQSYQAFGAQLSAFHAQFVQSLTNGARSYVVAEAT
SAAPLQDLLGVVNAPAQALLGRPLIGNGANGADGTGAPGGPGGLLLGNGGNGGSGAPGQPGGAGGDAGLIGNGGTGGKGG
DGLVGSGAAGGVGGRGGWLLGNGGTGGAGGAAGATLVGGTGGVGGATGLIGSGGFGGAGGAAAGVGTTGGVGGSGGVGGV
FGNGGFGGAGGLGAAGGVGGAASYFGTGGGGGVGGDGAPGGDGGAGPLLIGNGGVGGLGGAGAAGGNGGAGGMLLGDGGA
GGQGGPAVAGVLGGMPGAGGNGGNANWFGSGGAGGQGGTGLAGTNGVNPGSIANPNTGANGTDNSGNGNQTGGNGGPGPA
GGVGEAGGVGGQGGLGESLDGNDGTGGKGGAGGTAGTDGGAGGAGGAGGIGETDGSAGGVATGGEGGDGATGGVDGGVGG
AGGKGGQGHNTGVGDAFGGDGGIGGDGNGALGAAGGNGGTGGAGGNGGRGGMLIGNGGAGGAGGTGGTGGGGAAGFAGGV
GGAGGEGLTDGAGTAEGGTGGLGGLGGVGGTGGMGGSGGVGGNGGAAGSLIGLGGGGGAGGVGGTGGIGGIGGAGGNGGA
GGAGTTTGGGATIGGGGGTGGVGGAGGTGGTGGAGGTTGGSGGAGGLIGWAGAAGGTGAGGTGGQGGLGGQGGNGGNGGT
GATGGQGGDFALGGNGGAGGAGGSPGGSSGIQGNMGPPGTQGADG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mycobacterial PE family. PGRS subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PG46_MYCBO (P0A691)

Other databases:

- EMBL:   BX248343
- RefSeq:   NP_856313.1
- ProteinModelPortal:   P0A691
- SMR:   P0A691
- EnsemblBacteria:   EBMYCT00000016441
- GeneID:   1091949
- GenomeReviews:   BX248333_GR
- KEGG:   mbo:Mb2667c
- GeneTree:   EBGT00050000014951
- HOGENOM:   HBG128029
- OMA:   ATGMVGP
- ProtClustDB:   CLSK799924
- BioCyc:   MBOV233413:MB2667C-MONOMER
- InterPro:   IPR000084

Pfam domain/function: PF00934 PE

EC number: NA

Molecular weight: Translated: 61872; Mature: 61741

Theoretical pI: Translated: 3.61; Mature: 3.61

Prosite motif: PS00227 TUBULIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAASDLANIGSTINAANAAAALPTTGVVAAAADEVSAAVAALFGSYAQSYQAFGAQLSAF
CCHHHHHHHCCHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HAQFVQSLTNGARSYVVAEATSAAPLQDLLGVVNAPAQALLGRPLIGNGANGADGTGAPG
HHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCCCCC
GPGGLLLGNGGNGGSGAPGQPGGAGGDAGLIGNGGTGGKGGDGLVGSGAAGGVGGRGGWL
CCCCEEEECCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCEE
LGNGGTGGAGGAAGATLVGGTGGVGGATGLIGSGGFGGAGGAAAGVGTTGGVGGSGGVGG
EECCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
VFGNGGFGGAGGLGAAGGVGGAASYFGTGGGGGVGGDGAPGGDGGAGPLLIGNGGVGGLG
CCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCC
GAGAAGGNGGAGGMLLGDGGAGGQGGPAVAGVLGGMPGAGGNGGNANWFGSGGAGGQGGT
CCCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHCCCCCCCCCCCCCCEECCCCCCCCCCC
GLAGTNGVNPGSIANPNTGANGTDNSGNGNQTGGNGGPGPAGGVGEAGGVGGQGGLGESL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
DGNDGTGGKGGAGGTAGTDGGAGGAGGAGGIGETDGSAGGVATGGEGGDGATGGVDGGVG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GAGGKGGQGHNTGVGDAFGGDGGIGGDGNGALGAAGGNGGTGGAGGNGGRGGMLIGNGGA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCEEEECCCC
GGAGGTGGTGGGGAAGFAGGVGGAGGEGLTDGAGTAEGGTGGLGGLGGVGGTGGMGGSGG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
VGGNGGAAGSLIGLGGGGGAGGVGGTGGIGGIGGAGGNGGAGGAGTTTGGGATIGGGGGT
CCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCC
GGVGGAGGTGGTGGAGGTTGGSGGAGGLIGWAGAAGGTGAGGTGGQGGLGGQGGNGGNGG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCC
TGATGGQGGDFALGGNGGAGGAGGSPGGSSGIQGNMGPPGTQGADG
CCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AASDLANIGSTINAANAAAALPTTGVVAAAADEVSAAVAALFGSYAQSYQAFGAQLSAF
CHHHHHHHCCHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HAQFVQSLTNGARSYVVAEATSAAPLQDLLGVVNAPAQALLGRPLIGNGANGADGTGAPG
HHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCCCCC
GPGGLLLGNGGNGGSGAPGQPGGAGGDAGLIGNGGTGGKGGDGLVGSGAAGGVGGRGGWL
CCCCEEEECCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCEE
LGNGGTGGAGGAAGATLVGGTGGVGGATGLIGSGGFGGAGGAAAGVGTTGGVGGSGGVGG
EECCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
VFGNGGFGGAGGLGAAGGVGGAASYFGTGGGGGVGGDGAPGGDGGAGPLLIGNGGVGGLG
CCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCC
GAGAAGGNGGAGGMLLGDGGAGGQGGPAVAGVLGGMPGAGGNGGNANWFGSGGAGGQGGT
CCCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHCCCCCCCCCCCCCCEECCCCCCCCCCC
GLAGTNGVNPGSIANPNTGANGTDNSGNGNQTGGNGGPGPAGGVGEAGGVGGQGGLGESL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
DGNDGTGGKGGAGGTAGTDGGAGGAGGAGGIGETDGSAGGVATGGEGGDGATGGVDGGVG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GAGGKGGQGHNTGVGDAFGGDGGIGGDGNGALGAAGGNGGTGGAGGNGGRGGMLIGNGGA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCEEEECCCC
GGAGGTGGTGGGGAAGFAGGVGGAGGEGLTDGAGTAEGGTGGLGGLGGVGGTGGMGGSGG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
VGGNGGAAGSLIGLGGGGGAGGVGGTGGIGGIGGAGGNGGAGGAGTTTGGGATIGGGGGT
CCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCC
GGVGGAGGTGGTGGAGGTTGGSGGAGGLIGWAGAAGGTGAGGTGGQGGLGGQGGNGGNGG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCC
TGATGGQGGDFALGGNGGAGGAGGSPGGSSGIQGNMGPPGTQGADG
CCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972