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The map label for this gene is 148662399

Identifier: 148662399

GI number: 148662399

Start: 2892043

End: 2893020

Strand: Direct

Name: 148662399

Synonym: MRA_2589

Alternate gene names: NA

Gene position: 2892043-2893020 (Clockwise)

Preceding gene: 148662397

Following gene: 148662401

Centisome position: 65.43

GC content: 66.26

Gene sequence:

>978_bases
ATGAGCCAGCCGCCAGAACATCCAGGCAATCCGGCCGACCCCCAGGGCGGCAATCAGGGCGCTGGAAGCTACCCGCCGCC
CGGCTACGGAGCGCCTCCCCCGCCACCAGGCTACGGCCCACCCCCGGGGACCTACCTGCCTCCCGGCTACAACGCACCCC
CGCCGCCCCCCGGCTATGGCCCACCGCCGGGCCCGCCGCCTCCCGGTTACCCGACGCATCTGCAATCGTCGGGTTTTAGC
GTGGGCGACGCGATCAGTTGGTCATGGAATAGGTTCACGCAGAACGCCGTAACGCTCGTCGTCCCGGTGCTCGCCTACGC
TGTGGCGTTGGCCGCGGTCATCGGCGCGACGGCCGGGCTCGTTGTCGCCCTATCGGACCGTGCTACTACCGCATACACCA
ACACCTCCGGCGTCTCTAGCGAATCCGTGGACATCACGATGACCCCGGCCGCGGGCATAGTCATGTTCCTCGGCTACATC
GCTCTATTCGCCCTGGTGCTCTACATGCACGCCGGAATTCTGACCGGCTGCCTTGACATTGCCGACGGAAAGCCGGTGAC
CATCGCGACGTTCTTTAGGCCGCGCAATCTGGGCCTGGTGCTGGTCACCGGACTGCTGATCGTCGCCGTCACCTTCATTG
GTGGCCTGCTCTGTGTCATTCCCGGCCTGATCTTTGGCTTCGTCGCCCAGTTCGCCGTCGCTTTTGCCGTCGACCGTTCC
ACTTCGCCGATCGACTCGGTAAAGGCCAGCATCGAGACGGTCGGGTCCAACATCGGTGGCAGTGTGCTGTCGTGGCTCGC
TCAGCTCACGGCGGTGCTCGTCGGCGAACTGCTGTGCTTTGTCGGCATGCTGATCGGCATTCCGGTCGCCGCGCTCATCC
ACGTCTACACCTACCGGAAGCTGTCGGGTGGCCAAGTCGTTGAGGCAGTCCGGCCAGCGCCCCCGGTCGGCTGGCCGCCC
GGCCCCCAGCTCGCATAG

Upstream 100 bases:

>100_bases
GAATAATCCGCGCGCCTTCGGCAAATATTTGCTAAGTTCCGGTTTGCTTAGCGTCGCGCGGGTACCGATAAAAGCGAACT
ACGAAGCGATTGGGACAGCG

Downstream 100 bases:

>100_bases
TCGGCACCCGCCGACGCCGGCTGGCCGTCTTGGCCCGCTGGATTTGTCACGCGCTCACCCGAATTGGCATCCGGGGCCTG
GAACGCGTTAGGGCAGTGGC

Product: putative proline and glycine rich transmembrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 325; Mature: 324

Protein sequence:

>325_residues
MSQPPEHPGNPADPQGGNQGAGSYPPPGYGAPPPPPGYGPPPGTYLPPGYNAPPPPPGYGPPPGPPPPGYPTHLQSSGFS
VGDAISWSWNRFTQNAVTLVVPVLAYAVALAAVIGATAGLVVALSDRATTAYTNTSGVSSESVDITMTPAAGIVMFLGYI
ALFALVLYMHAGILTGCLDIADGKPVTIATFFRPRNLGLVLVTGLLIVAVTFIGGLLCVIPGLIFGFVAQFAVAFAVDRS
TSPIDSVKASIETVGSNIGGSVLSWLAQLTAVLVGELLCFVGMLIGIPVAALIHVYTYRKLSGGQVVEAVRPAPPVGWPP
GPQLA

Sequences:

>Translated_325_residues
MSQPPEHPGNPADPQGGNQGAGSYPPPGYGAPPPPPGYGPPPGTYLPPGYNAPPPPPGYGPPPGPPPPGYPTHLQSSGFS
VGDAISWSWNRFTQNAVTLVVPVLAYAVALAAVIGATAGLVVALSDRATTAYTNTSGVSSESVDITMTPAAGIVMFLGYI
ALFALVLYMHAGILTGCLDIADGKPVTIATFFRPRNLGLVLVTGLLIVAVTFIGGLLCVIPGLIFGFVAQFAVAFAVDRS
TSPIDSVKASIETVGSNIGGSVLSWLAQLTAVLVGELLCFVGMLIGIPVAALIHVYTYRKLSGGQVVEAVRPAPPVGWPP
GPQLA
>Mature_324_residues
SQPPEHPGNPADPQGGNQGAGSYPPPGYGAPPPPPGYGPPPGTYLPPGYNAPPPPPGYGPPPGPPPPGYPTHLQSSGFSV
GDAISWSWNRFTQNAVTLVVPVLAYAVALAAVIGATAGLVVALSDRATTAYTNTSGVSSESVDITMTPAAGIVMFLGYIA
LFALVLYMHAGILTGCLDIADGKPVTIATFFRPRNLGLVLVTGLLIVAVTFIGGLLCVIPGLIFGFVAQFAVAFAVDRST
SPIDSVKASIETVGSNIGGSVLSWLAQLTAVLVGELLCFVGMLIGIPVAALIHVYTYRKLSGGQVVEAVRPAPPVGWPPG
PQLA

Specific function: Unknown

COG id: COG5473

COG function: function code S; Predicted integral membrane protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y2560_MYCTU (Q50738)

Other databases:

- EMBL:   BX842580
- EMBL:   AE000516
- PIR:   D70728
- RefSeq:   NP_217076.1
- RefSeq:   NP_337135.1
- ProteinModelPortal:   Q50738
- EnsemblBacteria:   EBMYCT00000002415
- EnsemblBacteria:   EBMYCT00000069392
- GeneID:   887363
- GeneID:   925678
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT2637
- KEGG:   mtu:Rv2560
- TIGR:   MT2637
- TubercuList:   Rv2560
- GeneTree:   EBGT00050000014860
- HOGENOM:   HBG580271
- OMA:   PPDGGYP
- ProtClustDB:   CLSK791924
- InterPro:   IPR018692

Pfam domain/function: PF09955 DUF2189

EC number: NA

Molecular weight: Translated: 33125; Mature: 32994

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1f864758)-; HASH(0x1f9f7ac8)-; HASH(0x1f5b492c)-; HASH(0x1e13dcd8)-;

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQPPEHPGNPADPQGGNQGAGSYPPPGYGAPPPPPGYGPPPGTYLPPGYNAPPPPPGYG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PPPGPPPPGYPTHLQSSGFSVGDAISWSWNRFTQNAVTLVVPVLAYAVALAAVIGATAGL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCE
VVALSDRATTAYTNTSGVSSESVDITMTPAAGIVMFLGYIALFALVLYMHAGILTGCLDI
EEEECCCCEEEECCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ADGKPVTIATFFRPRNLGLVLVTGLLIVAVTFIGGLLCVIPGLIFGFVAQFAVAFAVDRS
CCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TSPIDSVKASIETVGSNIGGSVLSWLAQLTAVLVGELLCFVGMLIGIPVAALIHVYTYRK
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSGGQVVEAVRPAPPVGWPPGPQLA
CCCCHHHHHHCCCCCCCCCCCCCCH
>Mature Secondary Structure 
SQPPEHPGNPADPQGGNQGAGSYPPPGYGAPPPPPGYGPPPGTYLPPGYNAPPPPPGYG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PPPGPPPPGYPTHLQSSGFSVGDAISWSWNRFTQNAVTLVVPVLAYAVALAAVIGATAGL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCE
VVALSDRATTAYTNTSGVSSESVDITMTPAAGIVMFLGYIALFALVLYMHAGILTGCLDI
EEEECCCCEEEECCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ADGKPVTIATFFRPRNLGLVLVTGLLIVAVTFIGGLLCVIPGLIFGFVAQFAVAFAVDRS
CCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TSPIDSVKASIETVGSNIGGSVLSWLAQLTAVLVGELLCFVGMLIGIPVAALIHVYTYRK
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSGGQVVEAVRPAPPVGWPPGPQLA
CCCCHHHHHHCCCCCCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036