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The map label for this gene is ppe37

Identifier: 148661938

GI number: 148661938

Start: 2390973

End: 2392394

Strand: Direct

Name: ppe37

Synonym: MRA_2138

Alternate gene names: 148661938

Gene position: 2390973-2392394 (Clockwise)

Preceding gene: 148661934

Following gene: 148661940

Centisome position: 54.09

GC content: 66.88

Gene sequence:

>1422_bases
GTGACCTTCCCGATGTGGTTCGCAGTTCCGCCGGAAGTGCCGTCAGCATGGCTGTCCACCGGCATGGGCCCCGGTCCGCT
GCTGGCCGCGGCCAGGGCGTGGCACGCGCTGGCCGCGCAATACACCGAAATTGCAACGGAACTCGCAAGCGTGCTCGCTG
CGGTGCAGGCAAGCTCGTGGCAGGGGCCCAGCGCCGACCGGTTCGTCGTCGCCCATCAACCGTTCCGGTATTGGCTAACC
CACGCTGCCACGGTGGCCACCGCAGCAGCCGCCGCGCACGAAACGGCCGCCGCCGGGTATACGTCCGCATTGGGGGGCAT
GCCTACGCTAGCCGAGTTGGCGGCCAACCATGCCATGCACGGCGCTCTGGTGACCACCAACTTCTTCGGTGTCAACACCA
TCCCGATCGCCCTCAACGAGGCCGACTACCTGCGCATGTGGATCCAGGCCGCCACCGTCATGAGCCACTATCAAGCCGTC
GCGCACGAAAGCGTGGCGGCGACCCCCAGCACGCCGCCGGCGCCGCAGATAGTGACCAGTGCGGCCAGCTCGGCGGCTAG
CAGCAGCTTCCCCGACCCGACCAAATTGATCCTGCAGCTACTCAAGGATTTCCTGGAGCTGCTGCGCTATCTGGCTGTTG
AGCTGCTGCCGGGGCCGCTCGGCGACCTCATCGCCCAGGTGTTGGACTGGTTCATCTCGTTCGTGTCCGGTCCAGTCTTC
ACGTTTCTCGCCTACCTGGTGCTGGACCCACTGATCTATTTCGGACCGTTCGCCCCGCTGACGAGTCCGGTCCTGTTGCC
TGCCGGGCTGACCGGGCTTGCCGGGCTCGGTGCGGTATCGGGGCCGGCCGGACCAATGGTCGAACGTGTGCACTCCGATG
GTCCCAGCCGGCAAAGCTGGCCTGCGGCCACCGGAGTCACCCTGGTGGGTACCAACCCGGCTGCCCTGGTTACCACGCCC
GCACCCGCTCCGACCACGTCCGCGGCACCGACGGCACCGTCGACTCCCGGATCCAGTGCCGCCCAAGGCCTTTACGCGGT
CGGTGGTCCCGACGGGGAAGGGTTCAACCCGATCGCCAAGACGACAGCACTCGCCGGTGTTACCACCGATGCCGCCGCAC
CTGCCGCCAAACTGCCCGGCGACCAAGCTCAGAGCAGCGCCAGCAAAGCAACAAGACTGCGGCGACGTCTCCGGCAACAC
CGCTTCGAGTTTCTGGCCGACGACGGCCGCCTGACCATGCCAAACACACCGGAGATGGCAGACGTCGCCGCCGGCAACCG
TGGATTGGATGCGCTGGGGTTCGCCGGCACGATCCCAAAATCGGCGCCCGGATCAGCGACCGGGCTTACTCACCTAGGCG
GCGGATTCGCCGACGTCCTGTCGCAGCCGATGCTTCCGCACACGTGGGACGGGTCAGATTAA

Upstream 100 bases:

>100_bases
TTGACGCCACACGTTCGCCACCGCCGCGCCGCGCATTAGGGCATCCTAATATAGGTTAGGCTACCCTAGTTATTCCTGTG
GTCGAAGGAGGCAGCCGAAC

Downstream 100 bases:

>100_bases
ACGTTGAAGTACTTGGCTTCCGGATGGTGCAGGACGAACGCGTCGGTCGACTGTTCGGGATGCAGCTGTAATTCCTCGGA
TAACGTCACACCGATGCGTT

Product: PPE family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 473; Mature: 472

Protein sequence:

>473_residues
MTFPMWFAVPPEVPSAWLSTGMGPGPLLAAARAWHALAAQYTEIATELASVLAAVQASSWQGPSADRFVVAHQPFRYWLT
HAATVATAAAAAHETAAAGYTSALGGMPTLAELAANHAMHGALVTTNFFGVNTIPIALNEADYLRMWIQAATVMSHYQAV
AHESVAATPSTPPAPQIVTSAASSAASSSFPDPTKLILQLLKDFLELLRYLAVELLPGPLGDLIAQVLDWFISFVSGPVF
TFLAYLVLDPLIYFGPFAPLTSPVLLPAGLTGLAGLGAVSGPAGPMVERVHSDGPSRQSWPAATGVTLVGTNPAALVTTP
APAPTTSAAPTAPSTPGSSAAQGLYAVGGPDGEGFNPIAKTTALAGVTTDAAAPAAKLPGDQAQSSASKATRLRRRLRQH
RFEFLADDGRLTMPNTPEMADVAAGNRGLDALGFAGTIPKSAPGSATGLTHLGGGFADVLSQPMLPHTWDGSD

Sequences:

>Translated_473_residues
MTFPMWFAVPPEVPSAWLSTGMGPGPLLAAARAWHALAAQYTEIATELASVLAAVQASSWQGPSADRFVVAHQPFRYWLT
HAATVATAAAAAHETAAAGYTSALGGMPTLAELAANHAMHGALVTTNFFGVNTIPIALNEADYLRMWIQAATVMSHYQAV
AHESVAATPSTPPAPQIVTSAASSAASSSFPDPTKLILQLLKDFLELLRYLAVELLPGPLGDLIAQVLDWFISFVSGPVF
TFLAYLVLDPLIYFGPFAPLTSPVLLPAGLTGLAGLGAVSGPAGPMVERVHSDGPSRQSWPAATGVTLVGTNPAALVTTP
APAPTTSAAPTAPSTPGSSAAQGLYAVGGPDGEGFNPIAKTTALAGVTTDAAAPAAKLPGDQAQSSASKATRLRRRLRQH
RFEFLADDGRLTMPNTPEMADVAAGNRGLDALGFAGTIPKSAPGSATGLTHLGGGFADVLSQPMLPHTWDGSD
>Mature_472_residues
TFPMWFAVPPEVPSAWLSTGMGPGPLLAAARAWHALAAQYTEIATELASVLAAVQASSWQGPSADRFVVAHQPFRYWLTH
AATVATAAAAAHETAAAGYTSALGGMPTLAELAANHAMHGALVTTNFFGVNTIPIALNEADYLRMWIQAATVMSHYQAVA
HESVAATPSTPPAPQIVTSAASSAASSSFPDPTKLILQLLKDFLELLRYLAVELLPGPLGDLIAQVLDWFISFVSGPVFT
FLAYLVLDPLIYFGPFAPLTSPVLLPAGLTGLAGLGAVSGPAGPMVERVHSDGPSRQSWPAATGVTLVGTNPAALVTTPA
PAPTTSAAPTAPSTPGSSAAQGLYAVGGPDGEGFNPIAKTTALAGVTTDAAAPAAKLPGDQAQSSASKATRLRRRLRQHR
FEFLADDGRLTMPNTPEMADVAAGNRGLDALGFAGTIPKSAPGSATGLTHLGGGFADVLSQPMLPHTWDGSD

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mycobacterial PPE family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PPE37_MYCTU (Q79FH3)

Other databases:

- EMBL:   BX842578
- PIR:   F70513
- RefSeq:   YP_177861.1
- ProteinModelPortal:   Q79FH3
- SMR:   Q79FH3
- EnsemblBacteria:   EBMYCT00000000034
- GeneID:   888710
- GenomeReviews:   AL123456_GR
- KEGG:   mtu:Rv2123
- TubercuList:   Rv2123
- GeneTree:   EBGT00050000014875
- HOGENOM:   HBG572308
- OMA:   HGANASE
- ProtClustDB:   CLSK824801
- InterPro:   IPR000030

Pfam domain/function: PF00823 PPE

EC number: NA

Molecular weight: Translated: 48564; Mature: 48432

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFPMWFAVPPEVPSAWLSTGMGPGPLLAAARAWHALAAQYTEIATELASVLAAVQASSW
CCCCCEEECCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
QGPSADRFVVAHQPFRYWLTHAATVATAAAAAHETAAAGYTSALGGMPTLAELAANHAMH
CCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHC
GALVTTNFFGVNTIPIALNEADYLRMWIQAATVMSHYQAVAHESVAATPSTPPAPQIVTS
CEEEEEEECCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
AASSAASSSFPDPTKLILQLLKDFLELLRYLAVELLPGPLGDLIAQVLDWFISFVSGPVF
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHH
TFLAYLVLDPLIYFGPFAPLTSPVLLPAGLTGLAGLGAVSGPAGPMVERVHSDGPSRQSW
HHHHHHHHHHHHHHCCCCHHCCCHHHHCCCHHHHHCCCCCCCCCHHHHHHHCCCCCCCCC
PAATGVTLVGTNPAALVTTPAPAPTTSAAPTAPSTPGSSAAQGLYAVGGPDGEGFNPIAK
CCCCCEEEECCCCCEEEECCCCCCCCCCCCCCCCCCCCHHHCCEEEECCCCCCCCCHHHH
TTALAGVTTDAAAPAAKLPGDQAQSSASKATRLRRRLRQHRFEFLADDGRLTMPNTPEMA
HHHHHCCCCHHCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCHH
DVAAGNRGLDALGFAGTIPKSAPGSATGLTHLGGGFADVLSQPMLPHTWDGSD
HHHCCCCCCCHHCCCCCCCCCCCCCCCCHHHHCCCHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
TFPMWFAVPPEVPSAWLSTGMGPGPLLAAARAWHALAAQYTEIATELASVLAAVQASSW
CCCCEEECCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
QGPSADRFVVAHQPFRYWLTHAATVATAAAAAHETAAAGYTSALGGMPTLAELAANHAMH
CCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHC
GALVTTNFFGVNTIPIALNEADYLRMWIQAATVMSHYQAVAHESVAATPSTPPAPQIVTS
CEEEEEEECCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
AASSAASSSFPDPTKLILQLLKDFLELLRYLAVELLPGPLGDLIAQVLDWFISFVSGPVF
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHH
TFLAYLVLDPLIYFGPFAPLTSPVLLPAGLTGLAGLGAVSGPAGPMVERVHSDGPSRQSW
HHHHHHHHHHHHHHCCCCHHCCCHHHHCCCHHHHHCCCCCCCCCHHHHHHHCCCCCCCCC
PAATGVTLVGTNPAALVTTPAPAPTTSAAPTAPSTPGSSAAQGLYAVGGPDGEGFNPIAK
CCCCCEEEECCCCCEEEECCCCCCCCCCCCCCCCCCCCHHHCCEEEECCCCCCCCCHHHH
TTALAGVTTDAAAPAAKLPGDQAQSSASKATRLRRRLRQHRFEFLADDGRLTMPNTPEMA
HHHHHCCCCHHCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCHH
DVAAGNRGLDALGFAGTIPKSAPGSATGLTHLGGGFADVLSQPMLPHTWDGSD
HHHCCCCCCCHHCCCCCCCCCCCCCCCCHHHHCCCHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230