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The map label for this gene is yggA [C]

Identifier: 148661797

GI number: 148661797

Start: 2239911

End: 2240510

Strand: Direct

Name: yggA [C]

Synonym: MRA_1999

Alternate gene names: 148661797

Gene position: 2239911-2240510 (Clockwise)

Preceding gene: 148661795

Following gene: 148661798

Centisome position: 50.68

GC content: 66.17

Gene sequence:

>600_bases
GTGAACTCACCACTGGTCGTCGGCTTCCTGGCCTGCTTCACGCTGATCGCCGCGATTGGCGCGCAGAACGCATTCGTGCT
GCGGCAGGGAATCCAGCGTGAGCACGTGCTGCCGGTGGTGGCGCTGTGCACGGTGTCCGACATCGTGCTGATCGCCGCCG
GTATCGCGGGGTTCGGCGCATTGATCGGCGCACATCCGCGTGCGCTCAATGTCGTCAAGTTTGGCGGCGCCGCCTTCCTA
ATCGGCTACGGGCTACTTGCGGCCCGGCGGGCGTGGCGACCTGTTGCGCTGATCCCATCTGGCGCCACGCCGGTTCGCTT
AGCCGAGGTCCTGGTGACCTGTGCGGCATTCACGTTCCTCAACCCACACGTCTACCTCGACACCGTCGTGTTGCTAGGCG
CGCTGGCCAACGAGCACAGCGACCAGCGCTGGCTGTTCGGCCTCGGCGCGGTCACAGCCAGTGCGGTATGGTTCGCCACC
CTCGGGTTCGGAGCCGGCCGGTTGCGCGGGCTGTTCACCAACCCCGGCTCGTGGAGAATCCTCGACGGCCTGATCGCGGT
CATGATGGTTGCGCTGGGAATCTCGCTGACCGTGACCTAG

Upstream 100 bases:

>100_bases
TAGACCATCTGCGGAGCGTCGCACTGCACATTAATAATGCTAATGTAAATGAAGAATTATTAGCTATACTGACCCATACA
AACTGCCTAGTGTCGATTGC

Downstream 100 bases:

>100_bases
TACAGCACGTGTGCACACGCGGGTTGGACCACGTGATCGTCGATGGGCACATACCGTTCGGCAGGAGGGCGCGCGGTCAG
TCTGCACAACTCAGTCACCA

Product: putative integral membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 199; Mature: 199

Protein sequence:

>199_residues
MNSPLVVGFLACFTLIAAIGAQNAFVLRQGIQREHVLPVVALCTVSDIVLIAAGIAGFGALIGAHPRALNVVKFGGAAFL
IGYGLLAARRAWRPVALIPSGATPVRLAEVLVTCAAFTFLNPHVYLDTVVLLGALANEHSDQRWLFGLGAVTASAVWFAT
LGFGAGRLRGLFTNPGSWRILDGLIAVMMVALGISLTVT

Sequences:

>Translated_199_residues
MNSPLVVGFLACFTLIAAIGAQNAFVLRQGIQREHVLPVVALCTVSDIVLIAAGIAGFGALIGAHPRALNVVKFGGAAFL
IGYGLLAARRAWRPVALIPSGATPVRLAEVLVTCAAFTFLNPHVYLDTVVLLGALANEHSDQRWLFGLGAVTASAVWFAT
LGFGAGRLRGLFTNPGSWRILDGLIAVMMVALGISLTVT
>Mature_199_residues
MNSPLVVGFLACFTLIAAIGAQNAFVLRQGIQREHVLPVVALCTVSDIVLIAAGIAGFGALIGAHPRALNVVKFGGAAFL
IGYGLLAARRAWRPVALIPSGATPVRLAEVLVTCAAFTFLNPHVYLDTVVLLGALANEHSDQRWLFGLGAVTASAVWFAT
LGFGAGRLRGLFTNPGSWRILDGLIAVMMVALGISLTVT

Specific function: Unknown

COG id: COG1279

COG function: function code R; Lysine efflux permease

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the LysE/ArgO transporter (TC 2.A.75) family

Homologues:

Organism=Escherichia coli, GI1789290, Length=147, Percent_Identity=42.1768707482993, Blast_Score=104, Evalue=4e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y1986_MYCTU (P64903)

Other databases:

- EMBL:   BX842578
- EMBL:   AE000516
- PIR:   H70756
- RefSeq:   NP_216502.1
- RefSeq:   NP_336501.1
- EnsemblBacteria:   EBMYCT00000003355
- EnsemblBacteria:   EBMYCT00000070985
- GeneID:   885635
- GeneID:   923447
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT2040
- KEGG:   mtu:Rv1986
- TIGR:   MT2040
- TubercuList:   Rv1986
- GeneTree:   EBGT00050000016872
- HOGENOM:   HBG683136
- OMA:   MRYGGAA
- ProtClustDB:   CLSK791539
- InterPro:   IPR004777
- InterPro:   IPR001123
- TIGRFAMs:   TIGR00948

Pfam domain/function: PF01810 LysE

EC number: NA

Molecular weight: Translated: 20776; Mature: 20776

Theoretical pI: Translated: 10.04; Mature: 10.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1f2bcc24)-; HASH(0x1efe886c)-; HASH(0x1dc20e28)-; HASH(0x1f37c8b0)-; HASH(0x1f49325c)-; HASH(0x1ed52398)-;

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSPLVVGFLACFTLIAAIGAQNAFVLRQGIQREHVLPVVALCTVSDIVLIAAGIAGFGA
CCCCHHHHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIGAHPRALNVVKFGGAAFLIGYGLLAARRAWRPVALIPSGATPVRLAEVLVTCAAFTFL
HHCCCCCCEEEEEECCHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHC
NPHVYLDTVVLLGALANEHSDQRWLFGLGAVTASAVWFATLGFGAGRLRGLFTNPGSWRI
CCHHHHHHHHHHHHHHCCCCCCHHEEEHHHHHHHHHHHHHHCCCCHHHCEEECCCCCHHH
LDGLIAVMMVALGISLTVT
HHHHHHHHHHHHCCCEEEH
>Mature Secondary Structure
MNSPLVVGFLACFTLIAAIGAQNAFVLRQGIQREHVLPVVALCTVSDIVLIAAGIAGFGA
CCCCHHHHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIGAHPRALNVVKFGGAAFLIGYGLLAARRAWRPVALIPSGATPVRLAEVLVTCAAFTFL
HHCCCCCCEEEEEECCHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHC
NPHVYLDTVVLLGALANEHSDQRWLFGLGAVTASAVWFATLGFGAGRLRGLFTNPGSWRI
CCHHHHHHHHHHHHHHCCCCCCHHEEEHHHHHHHHHHHHHHCCCCHHHCEEECCCCCHHH
LDGLIAVMMVALGISLTVT
HHHHHHHHHHHHCCCEEEH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036