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The map label for this gene is blaI

Identifier: 148661652

GI number: 148661652

Start: 2106115

End: 2106531

Strand: Reverse

Name: blaI

Synonym: MRA_1857

Alternate gene names: 148661652

Gene position: 2106531-2106115 (Counterclockwise)

Preceding gene: 148661660

Following gene: 148661651

Centisome position: 47.66

GC content: 64.75

Gene sequence:

>417_bases
ATGGCCAAGCTGACACGGTTGGGGGATTTGGAACGCGCGGTCATGGACCATTTGTGGTCCAGGACGGAACCCCAAACCGT
TCGCCAAGTCCACGAAGCGTTGTCGGCGCGCCGCGACCTTGCCTACACGACGGTGATGACCGTGCTGCAACGGTTGGCAA
AGAAGAACCTCGTGCTGCAGATCCGCGACGATCGAGCCCACCGCTACGCTCCCGTGCACGGCCGCGACGAATTGGTCGCC
GGGCTGATGGTCGATGCATTGGCTCAGGCCGAGGACTCCGGCAGCAGGCAAGCCGCGCTGGTGCACTTCGTCGAGCGAGT
CGGTGCCGACGAGGCGGATGCGCTACGACGTGCGCTCGCCGAATTGGAAGCCGGTCATGGCAATCGGCCACCGGCTGGCG
CGGCAACGGAGACTTGA

Upstream 100 bases:

>100_bases
CCGGGTGCATAGGCCCGGTACGGCCGCCCGCCGGTTTGGATACGACAGCGAGTAGTAAGCCGGAGTACGCTGGTTTCAAC
CCGCAGGAGATGAACGAACA

Downstream 100 bases:

>100_bases
GGGAGACTAACGGCGTGTCCGCGCTGGCCTTCACCATCCTCGCGGTGCTGCTGGCTGGCCCGACCCCAGCCCTGCTAGCC
CGGGCAACGTGGCCACTGCG

Product: putative transcriptional regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 138; Mature: 137

Protein sequence:

>138_residues
MAKLTRLGDLERAVMDHLWSRTEPQTVRQVHEALSARRDLAYTTVMTVLQRLAKKNLVLQIRDDRAHRYAPVHGRDELVA
GLMVDALAQAEDSGSRQAALVHFVERVGADEADALRRALAELEAGHGNRPPAGAATET

Sequences:

>Translated_138_residues
MAKLTRLGDLERAVMDHLWSRTEPQTVRQVHEALSARRDLAYTTVMTVLQRLAKKNLVLQIRDDRAHRYAPVHGRDELVA
GLMVDALAQAEDSGSRQAALVHFVERVGADEADALRRALAELEAGHGNRPPAGAATET
>Mature_137_residues
AKLTRLGDLERAVMDHLWSRTEPQTVRQVHEALSARRDLAYTTVMTVLQRLAKKNLVLQIRDDRAHRYAPVHGRDELVAG
LMVDALAQAEDSGSRQAALVHFVERVGADEADALRRALAELEAGHGNRPPAGAATET

Specific function: Transcription regulator that binds to an inverted DNA repeat with the consensus sequence 5'-TAC[GT]AC-NNNNN-GT[AC]GTA-3' and regulates genes involved in antibiotic transport, detoxification and cell wall function. Also regulates its own transcription. Bin

COG id: COG3682

COG function: function code K; Predicted transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BlaI transcriptional regulatory family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): BLAI_MYCTU (P95163)

Other databases:

- EMBL:   AE000516
- EMBL:   BX842578
- PIR:   F70664
- RefSeq:   NP_216362.1
- RefSeq:   NP_336351.1
- PDB:   2G9W
- PDBsum:   2G9W
- ProteinModelPortal:   P95163
- SMR:   P95163
- EnsemblBacteria:   EBMYCT00000000312
- EnsemblBacteria:   EBMYCT00000069240
- GeneID:   885747
- GeneID:   923720
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT1894
- KEGG:   mtu:Rv1846c
- TIGR:   MT1894
- TubercuList:   Rv1846c
- GeneTree:   EBGT00050000015710
- HOGENOM:   HBG700245
- OMA:   MDHLWST
- ProtClustDB:   CLSK791428
- GO:   GO:0005737
- GO:   GO:0006350
- InterPro:   IPR005650
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10

Pfam domain/function: PF03965 Pencillinase_R

EC number: NA

Molecular weight: Translated: 15211; Mature: 15080

Theoretical pI: Translated: 7.19; Mature: 7.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKLTRLGDLERAVMDHLWSRTEPQTVRQVHEALSARRDLAYTTVMTVLQRLAKKNLVLQ
CCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
IRDDRAHRYAPVHGRDELVAGLMVDALAQAEDSGSRQAALVHFVERVGADEADALRRALA
EECCCCHHCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHH
ELEAGHGNRPPAGAATET
HHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AKLTRLGDLERAVMDHLWSRTEPQTVRQVHEALSARRDLAYTTVMTVLQRLAKKNLVLQ
CCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
IRDDRAHRYAPVHGRDELVAGLMVDALAQAEDSGSRQAALVHFVERVGADEADALRRALA
EECCCCHHCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHH
ELEAGHGNRPPAGAATET
HHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036