Click here to switch to the map view.

The map label for this gene is ppe33

Identifier: 148661615

GI number: 148661615

Start: 2061214

End: 2062620

Strand: Direct

Name: ppe33

Synonym: MRA_1821

Alternate gene names: 148661615

Gene position: 2061214-2062620 (Clockwise)

Preceding gene: 148661614

Following gene: 148661616

Centisome position: 46.63

GC content: 65.6

Gene sequence:

>1407_bases
ATGGATTTCGGATTGCAGCCACCGGAGATCACCTCCGGGGAGATGTACCTAGGTCCGGGCGCCGGTCCGATGTTGGCTGC
GGCAGTGGCCTGGGATGGGTTGGCGGCCGAATTGCAGTCCATGGCGGCCTCCTACGCCTCGATCGTCGAGGGCATGGCGA
GTGAGTCATGGTTGGGTCCGTCGTCGGCCGGTATGGCCGCTGCGGCCGCACCATATGTGACCTGGATGTCGGGTACCTCG
GCACAGGCCAAGGCGGCCGCTGACCAGGCCAGAGCCGCGGTGGTCGCCTACGAAACCGCGTTCGCGGCGGTGGTGCCACC
GCCGCAGATTGCGGCCAACCGCAGCCAGCTCATATCGCTGGTGGCGACCAACATTTTCGGACAAAACACCGCCGCGATCG
CAGCCACCGAAGCCGAATACGGCGAAATGTGGGCCCAGGACACCATGGCGATGTTCGGCTATGCCAGCTCCTCGGCGACC
GCCTCGCGGCTGACCCCGTTCACTGCACCGCCGCAGACCACCAACCCGTCCGGACTTGCCGGCCAGGCGGCCGCAACGGG
GCAAGCGACCGCCCTAGCGAGCGGCACCAATGCGGTGACAACCGCGCTTTCGAGTGCAGCGGCGCAGTTTCCGTTCGACA
TCATCCCGACCCTGCTGCAGGGCCTGGCCACACTCAGCACCCAATACACCCAACTCATGGGCCAACTCATTAACGCCATC
TTCGGGCCGACGGGCGCAACGACCTATCAGAACGTGTTTGTCACCGCAGCCAACGTCACCAAGTTCAGCACGTGGGCCAA
CGACGCCATGAGCGCGCCCAACCTGGGAATGACGGAGTTCAAGGTGTTCTGGCAACCCCCGCCGGCGCCCGAGATCCCCA
AATCGTCGTTGGGTGCCGGACTTGGCCTGCGGTCAGGGCTTAGCGCGGGCCTGGCCCACGCCGCATCGGCGGGTCTGGGT
CAGGCGAACCTGGTGGGAGACCTGTCGGTACCGCCCAGTTGGGCCTCAGCTACCCCGGCGGTCAGGCTAGTTGCCAACAC
ATTGCCGGCCACCAGCCTGGCTGCGGCCCCCGCGACACAGATCCCAGCAAACCTGCTCGGTCAGATGGCTCTGGGGAGCA
TGACCGGAGGTGCCCTCGGTGCCGCCGCCCCCGCCATCTACACGGGCAGTGGCGCCCGGGCCCGCGCCAATGGGGGAACG
CCCAGCGCTGAGCCGGTCAAGCTGGAGGCTGTCATCGCGCAGCTACAAAAGCAACCGGACGCAGTGCGACACTGGAATGT
CGATAAGGCCGATCTTGATGGCCTGCTGGATCGATTGTCGAAACAGCCCGGCATCCACGCGGTACACGTGTCGAACGGCG
ACAAACCCAAGGTTGCCTTGCCCGATACTCAGTTGGGTTCACACTGA

Upstream 100 bases:

>100_bases
GTTAGCCCCCACCGGAGAGGAGAGAAGGACGGTGTCATCGCCACTGTGGCCGGTGGCTGGCGGCCAGCCAGTTAGCGGCC
GGTTGAGGAAAGGTGTGGCA

Downstream 100 bases:

>100_bases
ACGTGATTCGAAATCCACACTGATACTGGAGGTGATTACCGGCTGAAGCAAAGCGCATTGGAAATCCAGGCTTAGACCAT
TGCCATGTGGCCGTGAGATT

Product: PPE family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 468; Mature: 468

Protein sequence:

>468_residues
MDFGLQPPEITSGEMYLGPGAGPMLAAAVAWDGLAAELQSMAASYASIVEGMASESWLGPSSAGMAAAAAPYVTWMSGTS
AQAKAAADQARAAVVAYETAFAAVVPPPQIAANRSQLISLVATNIFGQNTAAIAATEAEYGEMWAQDTMAMFGYASSSAT
ASRLTPFTAPPQTTNPSGLAGQAAATGQATALASGTNAVTTALSSAAAQFPFDIIPTLLQGLATLSTQYTQLMGQLINAI
FGPTGATTYQNVFVTAANVTKFSTWANDAMSAPNLGMTEFKVFWQPPPAPEIPKSSLGAGLGLRSGLSAGLAHAASAGLG
QANLVGDLSVPPSWASATPAVRLVANTLPATSLAAAPATQIPANLLGQMALGSMTGGALGAAAPAIYTGSGARARANGGT
PSAEPVKLEAVIAQLQKQPDAVRHWNVDKADLDGLLDRLSKQPGIHAVHVSNGDKPKVALPDTQLGSH

Sequences:

>Translated_468_residues
MDFGLQPPEITSGEMYLGPGAGPMLAAAVAWDGLAAELQSMAASYASIVEGMASESWLGPSSAGMAAAAAPYVTWMSGTS
AQAKAAADQARAAVVAYETAFAAVVPPPQIAANRSQLISLVATNIFGQNTAAIAATEAEYGEMWAQDTMAMFGYASSSAT
ASRLTPFTAPPQTTNPSGLAGQAAATGQATALASGTNAVTTALSSAAAQFPFDIIPTLLQGLATLSTQYTQLMGQLINAI
FGPTGATTYQNVFVTAANVTKFSTWANDAMSAPNLGMTEFKVFWQPPPAPEIPKSSLGAGLGLRSGLSAGLAHAASAGLG
QANLVGDLSVPPSWASATPAVRLVANTLPATSLAAAPATQIPANLLGQMALGSMTGGALGAAAPAIYTGSGARARANGGT
PSAEPVKLEAVIAQLQKQPDAVRHWNVDKADLDGLLDRLSKQPGIHAVHVSNGDKPKVALPDTQLGSH
>Mature_468_residues
MDFGLQPPEITSGEMYLGPGAGPMLAAAVAWDGLAAELQSMAASYASIVEGMASESWLGPSSAGMAAAAAPYVTWMSGTS
AQAKAAADQARAAVVAYETAFAAVVPPPQIAANRSQLISLVATNIFGQNTAAIAATEAEYGEMWAQDTMAMFGYASSSAT
ASRLTPFTAPPQTTNPSGLAGQAAATGQATALASGTNAVTTALSSAAAQFPFDIIPTLLQGLATLSTQYTQLMGQLINAI
FGPTGATTYQNVFVTAANVTKFSTWANDAMSAPNLGMTEFKVFWQPPPAPEIPKSSLGAGLGLRSGLSAGLAHAASAGLG
QANLVGDLSVPPSWASATPAVRLVANTLPATSLAAAPATQIPANLLGQMALGSMTGGALGAAAPAIYTGSGARARANGGT
PSAEPVKLEAVIAQLQKQPDAVRHWNVDKADLDGLLDRLSKQPGIHAVHVSNGDKPKVALPDTQLGSH

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mycobacterial PPE family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PPE33_MYCTU (Q79FJ5)

Other databases:

- EMBL:   BX842577
- EMBL:   AE000516
- PIR:   B70932
- RefSeq:   NP_336316.1
- RefSeq:   YP_177845.1
- HSSP:   Q79FE1
- ProteinModelPortal:   Q79FJ5
- SMR:   Q79FJ5
- EnsemblBacteria:   EBMYCT00000003845
- EnsemblBacteria:   EBMYCT00000070673
- GeneID:   885555
- GeneID:   923778
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT1857
- KEGG:   mtu:Rv1809
- TIGR:   MT1857
- TubercuList:   Rv1809
- GeneTree:   EBGT00050000014887
- HOGENOM:   HBG572308
- OMA:   VANDSMS
- ProtClustDB:   CLSK799847
- InterPro:   IPR022171
- InterPro:   IPR000030

Pfam domain/function: PF12484 PE_PPE_C; PF00823 PPE

EC number: NA

Molecular weight: Translated: 47157; Mature: 47157

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS00449 ATPASE_A

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFGLQPPEITSGEMYLGPGAGPMLAAAVAWDGLAAELQSMAASYASIVEGMASESWLGP
CCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
SSAGMAAAAAPYVTWMSGTSAQAKAAADQARAAVVAYETAFAAVVPPPQIAANRSQLISL
CCCCCHHHHCCCEEEECCCCHHHHHHHHHHHEEEEEEEHHEEEECCCCHHHCCHHHHHHH
VATNIFGQNTAAIAATEAEYGEMWAQDTMAMFGYASSSATASRLTPFTAPPQTTNPSGLA
HHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCCCCCCCCC
GQAAATGQATALASGTNAVTTALSSAAAQFPFDIIPTLLQGLATLSTQYTQLMGQLINAI
CCCCCCCCHHEEECCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGPTGATTYQNVFVTAANVTKFSTWANDAMSAPNLGMTEFKVFWQPPPAPEIPKSSLGAG
HCCCCCCEEEEEEEEECCCEEHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCHHHHCCC
LGLRSGLSAGLAHAASAGLGQANLVGDLSVPPSWASATPAVRLVANTLPATSLAAAPATQ
CCHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCHHHHHHHHCCCHHHHCCCCHH
IPANLLGQMALGSMTGGALGAAAPAIYTGSGARARANGGTPSAEPVKLEAVIAQLQKQPD
CCHHHHHHHHHHCCCCCCHHHCCCEEEECCCCEEECCCCCCCCCCCHHHHHHHHHHHCCC
AVRHWNVDKADLDGLLDRLSKQPGIHAVHVSNGDKPKVALPDTQLGSH
HHHHCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCEECCCCCCCCC
>Mature Secondary Structure
MDFGLQPPEITSGEMYLGPGAGPMLAAAVAWDGLAAELQSMAASYASIVEGMASESWLGP
CCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
SSAGMAAAAAPYVTWMSGTSAQAKAAADQARAAVVAYETAFAAVVPPPQIAANRSQLISL
CCCCCHHHHCCCEEEECCCCHHHHHHHHHHHEEEEEEEHHEEEECCCCHHHCCHHHHHHH
VATNIFGQNTAAIAATEAEYGEMWAQDTMAMFGYASSSATASRLTPFTAPPQTTNPSGLA
HHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCCCCCCCCC
GQAAATGQATALASGTNAVTTALSSAAAQFPFDIIPTLLQGLATLSTQYTQLMGQLINAI
CCCCCCCCHHEEECCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGPTGATTYQNVFVTAANVTKFSTWANDAMSAPNLGMTEFKVFWQPPPAPEIPKSSLGAG
HCCCCCCEEEEEEEEECCCEEHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCHHHHCCC
LGLRSGLSAGLAHAASAGLGQANLVGDLSVPPSWASATPAVRLVANTLPATSLAAAPATQ
CCHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCHHHHHHHHCCCHHHHCCCCHH
IPANLLGQMALGSMTGGALGAAAPAIYTGSGARARANGGTPSAEPVKLEAVIAQLQKQPD
CCHHHHHHHHHHCCCCCCHHHCCCEEEECCCCEEECCCCCCCCCCCHHHHHHHHHHHCCC
AVRHWNVDKADLDGLLDRLSKQPGIHAVHVSNGDKPKVALPDTQLGSH
HHHHCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036