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The map label for this gene is ppe22 [H]

Identifier: 148661613

GI number: 148661613

Start: 2058318

End: 2059529

Strand: Direct

Name: ppe22 [H]

Synonym: MRA_1819

Alternate gene names: 148661613

Gene position: 2058318-2059529 (Clockwise)

Preceding gene: 148661612

Following gene: 148661614

Centisome position: 46.57

GC content: 68.65

Gene sequence:

>1212_bases
ATGACTGCCGCACTTGACTTCGCCACGCTACCGCCCGAAATCAACTCGGCGCGTATGTATTCCGGCGCGGGCTCGGCCCC
GATGCTGGCCGCAGCGTCAGCCTGGCACGGCTTGTCCGCAGAACTGCGCGCCAGCGCACTGTCATACAGCTCGGTGCTTT
CGACGCTGACCGGTGAAGAATGGCACGGTCCGGCGTCGGCATCGATGACAGCCGCGGCCGCCCCCTACGTGGCCTGGATG
AGCGTCACCGCCGTCCGGGCCGAGCAGGCCGGGGCACAGGCGGAGGCTGCCGCTGCAGCGTACGAAGCCGCGTTCGCAGC
AACGGTGCCCCCGCCGGTCATCGAGGCCAACCGCGCCCAGCTCATGGCGCTGATCGCCACCAATGTGCTAGGCCAAAACG
CCCCCGCGATCGCGGCCACCGAGGCCCAGTACGCCGAAATGTGGTCCCAGGACGCGATGGCCATGTACGGCTACGCCGGC
GCCTCGGCAGCCGCTACCCAGCTGACCCCGTTCACCGAGCCGGTGCAGACTACCAACGCGTCCGGCCTGGCGGCCCAGTC
GGCTGCGATTGCCCACGCCACCGGCGCCTCGGCTGGTGCTCAGCAAACGACGCTGTCGCAGCTGATCGCCGCCATACCGT
CTGTACTGCAAGGACTTTCGTCATCGACTGCAGCCACGTTCGCGTCGGGGCCGTCCGGATTGCTGGGCATTGTCGGGTCT
GGATCTTCCTGGCTCGACAAACTCTGGGCGTTACTGGACCCCAACTCCAATTTCTGGAACACGATAGCTTCGTCCGGACT
GTTCTTGCCGAGTAACACGATTGCGCCCTTTTTGGGTCTACTCGGCGGCGTGGCAGCTGCGGATGCGGCCGGGGATGTGT
TGGGAGAGGCCACCAGTGGCGGGCTCGGTGGCGCGCTGGTGGCGCCGCTTGGCTCAGCGGGCGGGCTAGGCGGCACTGTC
GCGGCCGGCCTGGGCAACGCGGCCACCGTCGGAACCTTGTCGGTGCCGCCGAGCTGGACGGCGGCCGCACCACTAGCCAG
CCCCTTGGGCTCCGCGTTGGGAGGCACACCGATGGTGGCACCGCCCCCAGCAGTGGCGGCCGGCATGCCCGGAATGCCTT
TCGGCACCATGGGCGGTCAAGGCTTCGGGCGTGCCGTGCCCCAGTATGGCTTCCGCCCCAACTTCGTCGCACGACCGCCC
GCCGCCGGGTGA

Upstream 100 bases:

>100_bases
TGAATGAGGCGTTCGTCGCGATGTTGGGCGCCAGCGCGGATTCTTACGCGGCTACCGAAGCCGCCAACATCATTGCTGTG
AGCTAACGAGGAGATCAACG

Downstream 100 bases:

>100_bases
TCCCGTAGGGGGTGGGTTCCCTGGAAAGCGCCAGGGTCACGATGGCGCAGCCGAATAGCCGACAGTGCTTTTCTCTGCGA
ATACCGGAGTTGGTCGCGCG

Product: PPE family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 403; Mature: 402

Protein sequence:

>403_residues
MTAALDFATLPPEINSARMYSGAGSAPMLAAASAWHGLSAELRASALSYSSVLSTLTGEEWHGPASASMTAAAAPYVAWM
SVTAVRAEQAGAQAEAAAAAYEAAFAATVPPPVIEANRAQLMALIATNVLGQNAPAIAATEAQYAEMWSQDAMAMYGYAG
ASAAATQLTPFTEPVQTTNASGLAAQSAAIAHATGASAGAQQTTLSQLIAAIPSVLQGLSSSTAATFASGPSGLLGIVGS
GSSWLDKLWALLDPNSNFWNTIASSGLFLPSNTIAPFLGLLGGVAAADAAGDVLGEATSGGLGGALVAPLGSAGGLGGTV
AAGLGNAATVGTLSVPPSWTAAAPLASPLGSALGGTPMVAPPPAVAAGMPGMPFGTMGGQGFGRAVPQYGFRPNFVARPP
AAG

Sequences:

>Translated_403_residues
MTAALDFATLPPEINSARMYSGAGSAPMLAAASAWHGLSAELRASALSYSSVLSTLTGEEWHGPASASMTAAAAPYVAWM
SVTAVRAEQAGAQAEAAAAAYEAAFAATVPPPVIEANRAQLMALIATNVLGQNAPAIAATEAQYAEMWSQDAMAMYGYAG
ASAAATQLTPFTEPVQTTNASGLAAQSAAIAHATGASAGAQQTTLSQLIAAIPSVLQGLSSSTAATFASGPSGLLGIVGS
GSSWLDKLWALLDPNSNFWNTIASSGLFLPSNTIAPFLGLLGGVAAADAAGDVLGEATSGGLGGALVAPLGSAGGLGGTV
AAGLGNAATVGTLSVPPSWTAAAPLASPLGSALGGTPMVAPPPAVAAGMPGMPFGTMGGQGFGRAVPQYGFRPNFVARPP
AAG
>Mature_402_residues
TAALDFATLPPEINSARMYSGAGSAPMLAAASAWHGLSAELRASALSYSSVLSTLTGEEWHGPASASMTAAAAPYVAWMS
VTAVRAEQAGAQAEAAAAAYEAAFAATVPPPVIEANRAQLMALIATNVLGQNAPAIAATEAQYAEMWSQDAMAMYGYAGA
SAAATQLTPFTEPVQTTNASGLAAQSAAIAHATGASAGAQQTTLSQLIAAIPSVLQGLSSSTAATFASGPSGLLGIVGSG
SSWLDKLWALLDPNSNFWNTIASSGLFLPSNTIAPFLGLLGGVAAADAAGDVLGEATSGGLGGALVAPLGSAGGLGGTVA
AGLGNAATVGTLSVPPSWTAAAPLASPLGSALGGTPMVAPPPAVAAGMPGMPFGTMGGQGFGRAVPQYGFRPNFVARPPA
AG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mycobacterial PPE family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022171
- InterPro:   IPR000030 [H]

Pfam domain/function: PF12484 PE_PPE_C; PF00823 PPE [H]

EC number: NA

Molecular weight: Translated: 39243; Mature: 39112

Theoretical pI: Translated: 4.25; Mature: 4.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAALDFATLPPEINSARMYSGAGSAPMLAAASAWHGLSAELRASALSYSSVLSTLTGEE
CCCCCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCC
WHGPASASMTAAAAPYVAWMSVTAVRAEQAGAQAEAAAAAYEAAFAATVPPPVIEANRAQ
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHH
LMALIATNVLGQNAPAIAATEAQYAEMWSQDAMAMYGYAGASAAATQLTPFTEPVQTTNA
HHHHHHHHHHCCCCCCEEECHHHHHHHHHHCCHHHHCCCCCCHHHHHCCCCCCCHHHCCC
SGLAAQSAAIAHATGASAGAQQTTLSQLIAAIPSVLQGLSSSTAATFASGPSGLLGIVGS
CCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCEEEEECC
GSSWLDKLWALLDPNSNFWNTIASSGLFLPSNTIAPFLGLLGGVAAADAAGDVLGEATSG
CHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GLGGALVAPLGSAGGLGGTVAAGLGNAATVGTLSVPPSWTAAAPLASPLGSALGGTPMVA
CCCCHHHHCCCCCCCCCHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCC
PPPAVAAGMPGMPFGTMGGQGFGRAVPQYGFRPNFVARPPAAG
CCCHHHCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TAALDFATLPPEINSARMYSGAGSAPMLAAASAWHGLSAELRASALSYSSVLSTLTGEE
CCCCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCC
WHGPASASMTAAAAPYVAWMSVTAVRAEQAGAQAEAAAAAYEAAFAATVPPPVIEANRAQ
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHH
LMALIATNVLGQNAPAIAATEAQYAEMWSQDAMAMYGYAGASAAATQLTPFTEPVQTTNA
HHHHHHHHHHCCCCCCEEECHHHHHHHHHHCCHHHHCCCCCCHHHHHCCCCCCCHHHCCC
SGLAAQSAAIAHATGASAGAQQTTLSQLIAAIPSVLQGLSSSTAATFASGPSGLLGIVGS
CCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCEEEEECC
GSSWLDKLWALLDPNSNFWNTIASSGLFLPSNTIAPFLGLLGGVAAADAAGDVLGEATSG
CHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GLGGALVAPLGSAGGLGGTVAAGLGNAATVGTLSVPPSWTAAAPLASPLGSALGGTPMVA
CCCCHHHHCCCCCCCCCHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCC
PPPAVAAGMPGMPFGTMGGQGFGRAVPQYGFRPNFVARPPAAG
CCCHHHCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]