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The map label for this gene is ppe28

Identifier: 148661606

GI number: 148661606

Start: 2049385

End: 2051352

Strand: Direct

Name: ppe28

Synonym: MRA_1813

Alternate gene names: 148661606

Gene position: 2049385-2051352 (Clockwise)

Preceding gene: 148661605

Following gene: 148661607

Centisome position: 46.37

GC content: 63.57

Gene sequence:

>1968_bases
ATGCTGCCGAATTTCGCGGTGCTGCCCCCCGAGGTCAATTCGGCGAGGGTGTTCGCCGGTGCGGGGTCGGCGCCGATGTT
AGCGGCAGCGGCCGCCTGGGATGATCTAGCCTCCGAGCTGCATTGTGCTGCAATGTCATTCGGGTCGGTTACGTCGGGAT
TGGTGGTTGGGTGGTGGCAGGGATCGGCGTCGGCGGCGATGGTGGACGCAGCCGCGTCGTACATCGGGTGGCTGAGCACG
TCGGCTGCCCACGCCGAGGGCGCGGCCGGTCTGGCTCGGGCCGCGGTATCGGTGTTCGAGGAGGCGCTGGCCGCGACGGT
GCATCCGGCGATGGTTGCGGCAAATCGCGCCCAGGTGGCGTCGCTGGTAGCGTCGAACTTGTTTGGGCAGAACGCGCCTG
CGATCGCCGCGCTCGAATCCTTGTATGAGTGTATGTGGGCCCAGGATGCAGCGGCCATGGCGGGTTATTACGTTGGGGCT
TCGGCGGTGGCCACACAGTTGGCATCGTGGCTGCAACGGCTACAGAGCATCCCCGGCGCCGCCAGTCTTGATGCCCGTCT
GCCGAGCTCGGCCGAGGCACCGATGGGAGTCGTCCGCGCGGTCAACAGCGCGATCGCCGCCAATGCGGCTGCGGCACAAA
CCGTTGGCCTGGTCATGGGAGGCAGCGGCACGCCAATACCGTCGGCCAGATATGTCGAGCTCGCGAACGCGCTGTACATG
AGTGGCAGCGTCCCGGGTGTTATCGCGCAGGCGCTCTTCACGCCCCAAGGGCTCTACCCGGTGGTCGTGATCAAGAACCT
CACTTTCGATTCCTCGGTGGCGCAGGGTGCCGTCATTCTCGAAAGTGCGATTCGGCAGCAAATTGCCGCCGGCAACAACG
TCACCGTCTTCGGCTACTCGCAGAGCGCCACGATCTCGTCACTAGTGATGGCCAATCTTGCGGCTTCGGCCGACCCGCCG
TCTCCAGACGAGCTTTCCTTCACGCTGATCGGCAATCCCAACAACCCCAATGGCGGGGTTGCCACCAGGTTCCCGGGGAT
CTCCTTTCCAAGCTTGGGCGTGACGGCCACCGGGGCCACTCCGCACAATCTGTACCCGACCAAGATCTACACCATCGAAT
ACGACGGCGTCGCCGACTTTCCGCGGTACCCGCTCAACTTTGTGTCGACCCTCAACGCCATTGCCGGCACCTACTACGTG
CACTCCAACTACTTCATCCTGACGCCGGAACAAATTGACGCAGCGGTTCCGCTGACCAATACGGTCGGTCCCACGATGAC
CCAGTACTACATCATTCGCACGGAGAACCTGCCGCTGCTAGAGCCACTGCGATCGGTGCCGATCGTGGGGAACCCACTGG
CGAACCTGGTTCAACCAAACTTGAAGGTGATTGTTAACCTGGGCTACGGCGACCCGGCCTATGGTTATTCGACCTCGCCG
CCCAATGTTGCGACTCCGTTCGGGTTGTTCCCAGAGGTCAGCCCGGTCGTCATCGCCGACGCTCTCGTCGCCGGGACCCA
GCAGGGAATCGGCGATTTCGCCTACGACGTCAGCCACCTCGAACTGCCGTTGCCGGCAGACGGGTCGACGATGCCAAGCA
CCGCACCGGGCTCGGGTACGCCGGTCCCCCCGCTCTCGATCGACAGCCTGATAGACGACCTGCAGGTGGCTAACCGCAAC
CTCGCCAACACGATTTCGAAGGTGGCCGCGACGAGCTACGCGACGGTGCTCCCAACCGCCGACATCGCCAATGCGGCGTT
GACGATCGTGCCGTCGTACAACATCCACCTTTTTTTGGAGGGCATCCAGCAAGCGCTCAAGGGCGACCCGATGGGACTCG
TCAACGCGGTCGGATACCCACTCGCGGCCGACGTGGCACTGTTCACGGCCGCAGGCGGTCTTCAGCTCTTGATCATCATC
AGCGCGGGCCGAACGATTGCCAATGACATCTCGGCCATTGTCCCCTGA

Upstream 100 bases:

>100_bases
GCCCCGTTCGGGATCTGTACGCACTTTCATCCGACTGCGCGGTTGTTTGTTAGCGCATCGGATGAAAGTGTGCCGTCTCG
GCTGAGGAAGGACCGTCGCG

Downstream 100 bases:

>100_bases
TCGTGTTTTGCGTGAACTTTAAAGCGTTGTGCTGAGGTATGTTCCGCTCGCGTGTGGGGCGGCCCGCGCGACCACCTATG
CATGAGCGCCAATGGTCGAG

Product: PPE family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 655; Mature: 655

Protein sequence:

>655_residues
MLPNFAVLPPEVNSARVFAGAGSAPMLAAAAAWDDLASELHCAAMSFGSVTSGLVVGWWQGSASAAMVDAAASYIGWLST
SAAHAEGAAGLARAAVSVFEEALAATVHPAMVAANRAQVASLVASNLFGQNAPAIAALESLYECMWAQDAAAMAGYYVGA
SAVATQLASWLQRLQSIPGAASLDARLPSSAEAPMGVVRAVNSAIAANAAAAQTVGLVMGGSGTPIPSARYVELANALYM
SGSVPGVIAQALFTPQGLYPVVVIKNLTFDSSVAQGAVILESAIRQQIAAGNNVTVFGYSQSATISSLVMANLAASADPP
SPDELSFTLIGNPNNPNGGVATRFPGISFPSLGVTATGATPHNLYPTKIYTIEYDGVADFPRYPLNFVSTLNAIAGTYYV
HSNYFILTPEQIDAAVPLTNTVGPTMTQYYIIRTENLPLLEPLRSVPIVGNPLANLVQPNLKVIVNLGYGDPAYGYSTSP
PNVATPFGLFPEVSPVVIADALVAGTQQGIGDFAYDVSHLELPLPADGSTMPSTAPGSGTPVPPLSIDSLIDDLQVANRN
LANTISKVAATSYATVLPTADIANAALTIVPSYNIHLFLEGIQQALKGDPMGLVNAVGYPLAADVALFTAAGGLQLLIII
SAGRTIANDISAIVP

Sequences:

>Translated_655_residues
MLPNFAVLPPEVNSARVFAGAGSAPMLAAAAAWDDLASELHCAAMSFGSVTSGLVVGWWQGSASAAMVDAAASYIGWLST
SAAHAEGAAGLARAAVSVFEEALAATVHPAMVAANRAQVASLVASNLFGQNAPAIAALESLYECMWAQDAAAMAGYYVGA
SAVATQLASWLQRLQSIPGAASLDARLPSSAEAPMGVVRAVNSAIAANAAAAQTVGLVMGGSGTPIPSARYVELANALYM
SGSVPGVIAQALFTPQGLYPVVVIKNLTFDSSVAQGAVILESAIRQQIAAGNNVTVFGYSQSATISSLVMANLAASADPP
SPDELSFTLIGNPNNPNGGVATRFPGISFPSLGVTATGATPHNLYPTKIYTIEYDGVADFPRYPLNFVSTLNAIAGTYYV
HSNYFILTPEQIDAAVPLTNTVGPTMTQYYIIRTENLPLLEPLRSVPIVGNPLANLVQPNLKVIVNLGYGDPAYGYSTSP
PNVATPFGLFPEVSPVVIADALVAGTQQGIGDFAYDVSHLELPLPADGSTMPSTAPGSGTPVPPLSIDSLIDDLQVANRN
LANTISKVAATSYATVLPTADIANAALTIVPSYNIHLFLEGIQQALKGDPMGLVNAVGYPLAADVALFTAAGGLQLLIII
SAGRTIANDISAIVP
>Mature_655_residues
MLPNFAVLPPEVNSARVFAGAGSAPMLAAAAAWDDLASELHCAAMSFGSVTSGLVVGWWQGSASAAMVDAAASYIGWLST
SAAHAEGAAGLARAAVSVFEEALAATVHPAMVAANRAQVASLVASNLFGQNAPAIAALESLYECMWAQDAAAMAGYYVGA
SAVATQLASWLQRLQSIPGAASLDARLPSSAEAPMGVVRAVNSAIAANAAAAQTVGLVMGGSGTPIPSARYVELANALYM
SGSVPGVIAQALFTPQGLYPVVVIKNLTFDSSVAQGAVILESAIRQQIAAGNNVTVFGYSQSATISSLVMANLAASADPP
SPDELSFTLIGNPNNPNGGVATRFPGISFPSLGVTATGATPHNLYPTKIYTIEYDGVADFPRYPLNFVSTLNAIAGTYYV
HSNYFILTPEQIDAAVPLTNTVGPTMTQYYIIRTENLPLLEPLRSVPIVGNPLANLVQPNLKVIVNLGYGDPAYGYSTSP
PNVATPFGLFPEVSPVVIADALVAGTQQGIGDFAYDVSHLELPLPADGSTMPSTAPGSGTPVPPLSIDSLIDDLQVANRN
LANTISKVAATSYATVLPTADIANAALTIVPSYNIHLFLEGIQQALKGDPMGLVNAVGYPLAADVALFTAAGGLQLLIII
SAGRTIANDISAIVP

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mycobacterial PPE family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PPE28_MYCTU (Q79FK2)

Other databases:

- EMBL:   BX842577
- EMBL:   AE000516
- PIR:   A70931
- RefSeq:   NP_336306.1
- RefSeq:   YP_177839.1
- HSSP:   Q79FE1
- ProteinModelPortal:   Q79FK2
- SMR:   Q79FK2
- EnsemblBacteria:   EBMYCT00000000783
- EnsemblBacteria:   EBMYCT00000073093
- GeneID:   885465
- GeneID:   925128
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT1849
- KEGG:   mtu:Rv1800
- TIGR:   MT1849
- TubercuList:   Rv1800
- GeneTree:   EBGT00050000014926
- HOGENOM:   HBG569414
- OMA:   LESLYEW
- ProtClustDB:   CLSK799842
- InterPro:   IPR013228
- InterPro:   IPR000030

Pfam domain/function: PF08237 PE-PPE; PF00823 PPE

EC number: NA

Molecular weight: Translated: 67068; Mature: 67068

Theoretical pI: Translated: 4.24; Mature: 4.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPNFAVLPPEVNSARVFAGAGSAPMLAAAAAWDDLASELHCAAMSFGSVTSGLVVGWWQ
CCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEC
GSASAAMVDAAASYIGWLSTSAAHAEGAAGLARAAVSVFEEALAATVHPAMVAANRAQVA
CCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLVASNLFGQNAPAIAALESLYECMWAQDAAAMAGYYVGASAVATQLASWLQRLQSIPGA
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
ASLDARLPSSAEAPMGVVRAVNSAIAANAAAAQTVGLVMGGSGTPIPSARYVELANALYM
CCCCCCCCCCCCCHHHHHHHHHHHHHHCHHHHHEEEEEECCCCCCCCCHHHHHHHHHHHC
SGSVPGVIAQALFTPQGLYPVVVIKNLTFDSSVAQGAVILESAIRQQIAAGNNVTVFGYS
CCCCHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECC
QSATISSLVMANLAASADPPSPDELSFTLIGNPNNPNGGVATRFPGISFPSLGVTATGAT
CCHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCCEEECCCCCCCCCCCEEECCCC
PHNLYPTKIYTIEYDGVADFPRYPLNFVSTLNAIAGTYYVHSNYFILTPEQIDAAVPLTN
CCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHEEEEECCEEEECHHHCCCCCCCCC
TVGPTMTQYYIIRTENLPLLEPLRSVPIVGNPLANLVQPNLKVIVNLGYGDPAYGYSTSP
CCCCCCEEEEEEEECCCCHHHHHHCCCCCCCCHHHHCCCCEEEEEECCCCCCCCCCCCCC
PNVATPFGLFPEVSPVVIADALVAGTQQGIGDFAYDVSHLELPLPADGSTMPSTAPGSGT
CCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHCCHHHEEECCCCCCCCCCCCCCCCCC
PVPPLSIDSLIDDLQVANRNLANTISKVAATSYATVLPTADIANAALTIVPSYNIHLFLE
CCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHEECCCCHHCCCEEEEEECCCEEEHHH
GIQQALKGDPMGLVNAVGYPLAADVALFTAAGGLQLLIIISAGRTIANDISAIVP
HHHHHHCCCCCHHHHHCCCCHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHCCC
>Mature Secondary Structure
MLPNFAVLPPEVNSARVFAGAGSAPMLAAAAAWDDLASELHCAAMSFGSVTSGLVVGWWQ
CCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEC
GSASAAMVDAAASYIGWLSTSAAHAEGAAGLARAAVSVFEEALAATVHPAMVAANRAQVA
CCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLVASNLFGQNAPAIAALESLYECMWAQDAAAMAGYYVGASAVATQLASWLQRLQSIPGA
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
ASLDARLPSSAEAPMGVVRAVNSAIAANAAAAQTVGLVMGGSGTPIPSARYVELANALYM
CCCCCCCCCCCCCHHHHHHHHHHHHHHCHHHHHEEEEEECCCCCCCCCHHHHHHHHHHHC
SGSVPGVIAQALFTPQGLYPVVVIKNLTFDSSVAQGAVILESAIRQQIAAGNNVTVFGYS
CCCCHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECC
QSATISSLVMANLAASADPPSPDELSFTLIGNPNNPNGGVATRFPGISFPSLGVTATGAT
CCHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCCEEECCCCCCCCCCCEEECCCC
PHNLYPTKIYTIEYDGVADFPRYPLNFVSTLNAIAGTYYVHSNYFILTPEQIDAAVPLTN
CCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHEEEEECCEEEECHHHCCCCCCCCC
TVGPTMTQYYIIRTENLPLLEPLRSVPIVGNPLANLVQPNLKVIVNLGYGDPAYGYSTSP
CCCCCCEEEEEEEECCCCHHHHHHCCCCCCCCHHHHCCCCEEEEEECCCCCCCCCCCCCC
PNVATPFGLFPEVSPVVIADALVAGTQQGIGDFAYDVSHLELPLPADGSTMPSTAPGSGT
CCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHCCHHHEEECCCCCCCCCCCCCCCCCC
PVPPLSIDSLIDDLQVANRNLANTISKVAATSYATVLPTADIANAALTIVPSYNIHLFLE
CCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHEECCCCHHCCCEEEEEECCCEEEHHH
GIQQALKGDPMGLVNAVGYPLAADVALFTAAGGLQLLIIISAGRTIANDISAIVP
HHHHHHCCCCCHHHHHCCCCHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036