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The map label for this gene is ppe25 [H]

Identifier: 148661594

GI number: 148661594

Start: 2035113

End: 2036330

Strand: Direct

Name: ppe25 [H]

Synonym: MRA_1801

Alternate gene names: 148661594

Gene position: 2035113-2036330 (Clockwise)

Preceding gene: 148661593

Following gene: 148661595

Centisome position: 46.04

GC content: 66.34

Gene sequence:

>1218_bases
GTGCTATATTCGGCGCCTTTTCGATGCCGAGCGCGCGTCTCGTTGGCCACGTTTGGTGGCAATGCTCATCAGGGCTCATC
CGGATCGCCAACGCGATCGTGTGTGGAGAGGGAGGACTGGTTGGACTTCGGGGCGTTACCGCCGGAGATCAATTCGGGCC
GTATGTATTGCGGTCCGGGGTCGGGGCCGATGCTGGCTGCGGCCGCGGCCTGGGACGGGGTGGCCGTGGAGTTGGGGTTG
GCTGCGACCGGTTATGCGTCGGTGATAGCCGAGCTGACCGGTGCGCCGTGGGTGGGTGCGGCGTCGTTGTCGATGGTGGC
GGCGGCCACGCCGTATGTGGCCTGGCTGAGCCAAGCCGCGGCGCGGGCCGAGCAGGCGGGGATGCAGGCCGCGGCGGCCG
CGGCGGCTTATGAGGCCGCTTTTGTGATGACGGTGCCGCCGCCGGTGATTACGGCGAATCGGGTTTTGGTGATGACGCTG
ATTGCGACCAATTTTTTCGGTCAGAACTCGGCGGCGATCGCGGTCGCTGAGGCGCAGTACGCCGAAATGTGGGCGCAAGA
CGCCGTTGCTATGTATGGCTATGCGGCTGCGTCGGCGAGCGCGTCGCGGTTGATTCCGTTCGCGGCGCCGCCGAAGACCA
CCAACTCCGCTGGGGTGGTCGCACAGGTGGCTGCGGTCGCGGCGATGCCTGGACTGCTGCAACGACTTTCGTCGGCTGCA
TCGGTCAGCTGGTCGAATCCCAATGATTGGTGGCTCGTGCGGTTGCTGGGCTCGATTACCCCCACGGAAAGGACGACGAT
CGTTCGTTTGCTCGGTCAGTCGTACTTCGCGACGGGCATGGCGCAGTTCTTCGCCTCGATCGCACAGCAGCTGACCTTCG
GCCCAGGGGGCACAACGGCTGGCTCCGGCGGAGCCTGGTACCCAACGCCGCAATTCGCCGGCCTGGGTGCAAGCCGGGCG
GTGTCGGCGAGTTTGGCGCGGGCCAACAAGATTGGGGCTCTGTCGGTTCCGCCGAGCTGGGTCAAAACGACTGCACTGAC
CGAAAGCCCGGTCGCCCACGCGGTGAGCGCCAACCCTACCGTCGGTTCGTCACACGGACCGCATGGCCTGCTCCGCGGAC
TGCCGCTAGGGTCGCGGATCACTCGGCGTAGCGGCGCCTTTGCCCACCGATATGGGTTCCGTCACAGTGTGGTTGCCCGC
CCGCCATCGGCCGGATAA

Upstream 100 bases:

>100_bases
GAGGAATGAATATTTGGCGTCATCGGCGCTGGAGGCCGGTATTGCAATCTAATGTGTTTTCTATGCAACAGTTGCGCAGC
GACGCCGTTATCGACTAGCG

Downstream 100 bases:

>100_bases
CGCCATGACCTCAGCTCGGCAGAAATGACAATGCTCCCAAAGGCGTGAGCACCCGAAGACAACTAAGCAGGAGATCGCAT
GTCGTTTGTGACTACCCAAC

Product: PPE family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 405; Mature: 405

Protein sequence:

>405_residues
MLYSAPFRCRARVSLATFGGNAHQGSSGSPTRSCVEREDWLDFGALPPEINSGRMYCGPGSGPMLAAAAAWDGVAVELGL
AATGYASVIAELTGAPWVGAASLSMVAAATPYVAWLSQAAARAEQAGMQAAAAAAAYEAAFVMTVPPPVITANRVLVMTL
IATNFFGQNSAAIAVAEAQYAEMWAQDAVAMYGYAAASASASRLIPFAAPPKTTNSAGVVAQVAAVAAMPGLLQRLSSAA
SVSWSNPNDWWLVRLLGSITPTERTTIVRLLGQSYFATGMAQFFASIAQQLTFGPGGTTAGSGGAWYPTPQFAGLGASRA
VSASLARANKIGALSVPPSWVKTTALTESPVAHAVSANPTVGSSHGPHGLLRGLPLGSRITRRSGAFAHRYGFRHSVVAR
PPSAG

Sequences:

>Translated_405_residues
MLYSAPFRCRARVSLATFGGNAHQGSSGSPTRSCVEREDWLDFGALPPEINSGRMYCGPGSGPMLAAAAAWDGVAVELGL
AATGYASVIAELTGAPWVGAASLSMVAAATPYVAWLSQAAARAEQAGMQAAAAAAAYEAAFVMTVPPPVITANRVLVMTL
IATNFFGQNSAAIAVAEAQYAEMWAQDAVAMYGYAAASASASRLIPFAAPPKTTNSAGVVAQVAAVAAMPGLLQRLSSAA
SVSWSNPNDWWLVRLLGSITPTERTTIVRLLGQSYFATGMAQFFASIAQQLTFGPGGTTAGSGGAWYPTPQFAGLGASRA
VSASLARANKIGALSVPPSWVKTTALTESPVAHAVSANPTVGSSHGPHGLLRGLPLGSRITRRSGAFAHRYGFRHSVVAR
PPSAG
>Mature_405_residues
MLYSAPFRCRARVSLATFGGNAHQGSSGSPTRSCVEREDWLDFGALPPEINSGRMYCGPGSGPMLAAAAAWDGVAVELGL
AATGYASVIAELTGAPWVGAASLSMVAAATPYVAWLSQAAARAEQAGMQAAAAAAAYEAAFVMTVPPPVITANRVLVMTL
IATNFFGQNSAAIAVAEAQYAEMWAQDAVAMYGYAAASASASRLIPFAAPPKTTNSAGVVAQVAAVAAMPGLLQRLSSAA
SVSWSNPNDWWLVRLLGSITPTERTTIVRLLGQSYFATGMAQFFASIAQQLTFGPGGTTAGSGGAWYPTPQFAGLGASRA
VSASLARANKIGALSVPPSWVKTTALTESPVAHAVSANPTVGSSHGPHGLLRGLPLGSRITRRSGAFAHRYGFRHSVVAR
PPSAG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mycobacterial PPE family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022171
- InterPro:   IPR000030 [H]

Pfam domain/function: PF12484 PE_PPE_C; PF00823 PPE [H]

EC number: NA

Molecular weight: Translated: 41443; Mature: 41443

Theoretical pI: Translated: 9.97; Mature: 9.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYSAPFRCRARVSLATFGGNAHQGSSGSPTRSCVEREDWLDFGALPPEINSGRMYCGPG
CCCCCCCCEEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEECCC
SGPMLAAAAAWDGVAVELGLAATGYASVIAELTGAPWVGAASLSMVAAATPYVAWLSQAA
CCCEEEEECCCCCEEEEECCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
ARAEQAGMQAAAAAAAYEAAFVMTVPPPVITANRVLVMTLIATNFFGQNSAAIAVAEAQY
HHHHHHHHHHHHHHHHHHEEEEEECCCCCEECCHHHHHHHHHHHHCCCCCCEEEEEHHHH
AEMWAQDAVAMYGYAAASASASRLIPFAAPPKTTNSAGVVAQVAAVAAMPGLLQRLSSAA
HHHHHHHHHHHHHHHHHCCCCHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
SVSWSNPNDWWLVRLLGSITPTERTTIVRLLGQSYFATGMAQFFASIAQQLTFGPGGTTA
EECCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
GSGGAWYPTPQFAGLGASRAVSASLARANKIGALSVPPSWVKTTALTESPVAHAVSANPT
CCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEECCCCHHHHHHHCCCCCHHHHCCCCCC
VGSSHGPHGLLRGLPLGSRITRRSGAFAHRYGFRHSVVARPPSAG
CCCCCCCCHHHHCCCCCCHHHHHCCCHHHHCCCCCCEECCCCCCC
>Mature Secondary Structure
MLYSAPFRCRARVSLATFGGNAHQGSSGSPTRSCVEREDWLDFGALPPEINSGRMYCGPG
CCCCCCCCEEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEECCC
SGPMLAAAAAWDGVAVELGLAATGYASVIAELTGAPWVGAASLSMVAAATPYVAWLSQAA
CCCEEEEECCCCCEEEEECCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
ARAEQAGMQAAAAAAAYEAAFVMTVPPPVITANRVLVMTLIATNFFGQNSAAIAVAEAQY
HHHHHHHHHHHHHHHHHHEEEEEECCCCCEECCHHHHHHHHHHHHCCCCCCEEEEEHHHH
AEMWAQDAVAMYGYAAASASASRLIPFAAPPKTTNSAGVVAQVAAVAAMPGLLQRLSSAA
HHHHHHHHHHHHHHHHHCCCCHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
SVSWSNPNDWWLVRLLGSITPTERTTIVRLLGQSYFATGMAQFFASIAQQLTFGPGGTTA
EECCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
GSGGAWYPTPQFAGLGASRAVSASLARANKIGALSVPPSWVKTTALTESPVAHAVSANPT
CCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEECCCCHHHHHHHCCCCCHHHHCCCCCC
VGSSHGPHGLLRGLPLGSRITRRSGAFAHRYGFRHSVVARPPSAG
CCCCCCCCHHHHCCCCCCHHHHHCCCHHHHCCCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]