Click here to switch to the map view.

The map label for this gene is srpS [H]

Identifier: 148661581

GI number: 148661581

Start: 2016952

End: 2017698

Strand: Reverse

Name: srpS [H]

Synonym: MRA_1789

Alternate gene names: 148661581

Gene position: 2017698-2016952 (Counterclockwise)

Preceding gene: 148661584

Following gene: 148661573

Centisome position: 45.65

GC content: 66.53

Gene sequence:

>747_bases
GTGCCGCCTACGGAAGGAAAGTCGACAACGAATCGCGACGAAGGCATCCAGGTGCTCCGTCGCGCCGTCGCCGCGCTGGA
CGAAATAGCTGCCGAACCGGGACACCTGCGCCTAGTCGATCTCTGCGAGCGGCTGGGGCTGGCCAAATCGACGACTCGAC
GCTTGCTGGTCGGCCTGGTCGAGGTGGGGCTGGTTAGTGTCGATTCGCACGGCCGCTTCGCACTGGGCGAGCGTTTGCTG
GGATTCGGAAGTGTCACCGGAGCCCACATAGCCGCGGCGTTCCGGCCGACCGTCGAGCGAGTTGCCCGCGCGACCGACGG
CGAAACGGTCGACCTGTCGGTACTGCGCGGCCAGCGAATGTGGTTTGTCGACCAGATCGAATCGTCTTACCGGCTGCGTG
CGGTCTCAGCCGTCGGGCTCCGCTTCCCGTTGAACGGAACCGCGAATGGAAAAGCGGCGCTGGCTGCTCTCGACGACGCC
GACGCCGAGGCCGCGCTCTGCCGTCTGGATCCCATGGTGGCCGAAGGTCTACGGCGCGAGATCGTCGAGATCCGGCGCAC
CGGTATCGCTTTCGACCGCAACGAGCACACCCCAGGGATATCCGCGGCTGCGATCGCACGACGCGCCCTGGGCGACAACG
TGATCGCGATCTCGGTGCCGGCGCCCACCGCACGATTTCTGGAAAAAGAGCAGCGCATAATCGCCGCGTTGCGCGCCGCC
GCGGACTCGCCGGACTGGACTCGCTGA

Upstream 100 bases:

>100_bases
CGGAAGAAGTGCCGCCCGGCCGGTAGCGCCCTCATAGCAAAACTCCTGGTCCGTATTTCGAATCATTGTGATCCGTATTT
CGGTTCACTATATTGCAGTT

Downstream 100 bases:

>100_bases
TTGGGCTCCTGGATTCGAAGCCGATCCGTTTAGCTGGCGGCGGTGCTTCCCCACACCACCGCCAAGCTGGCATTACGCCG
CCGCATGCGCAAAAAGCTGA

Product: IclR family transcriptional regulator

Products: NA

Alternate protein names: Solvent efflux pump srpABC operon corepressor [H]

Number of amino acids: Translated: 248; Mature: 247

Protein sequence:

>248_residues
MPPTEGKSTTNRDEGIQVLRRAVAALDEIAAEPGHLRLVDLCERLGLAKSTTRRLLVGLVEVGLVSVDSHGRFALGERLL
GFGSVTGAHIAAAFRPTVERVARATDGETVDLSVLRGQRMWFVDQIESSYRLRAVSAVGLRFPLNGTANGKAALAALDDA
DAEAALCRLDPMVAEGLRREIVEIRRTGIAFDRNEHTPGISAAAIARRALGDNVIAISVPAPTARFLEKEQRIIAALRAA
ADSPDWTR

Sequences:

>Translated_248_residues
MPPTEGKSTTNRDEGIQVLRRAVAALDEIAAEPGHLRLVDLCERLGLAKSTTRRLLVGLVEVGLVSVDSHGRFALGERLL
GFGSVTGAHIAAAFRPTVERVARATDGETVDLSVLRGQRMWFVDQIESSYRLRAVSAVGLRFPLNGTANGKAALAALDDA
DAEAALCRLDPMVAEGLRREIVEIRRTGIAFDRNEHTPGISAAAIARRALGDNVIAISVPAPTARFLEKEQRIIAALRAA
ADSPDWTR
>Mature_247_residues
PPTEGKSTTNRDEGIQVLRRAVAALDEIAAEPGHLRLVDLCERLGLAKSTTRRLLVGLVEVGLVSVDSHGRFALGERLLG
FGSVTGAHIAAAFRPTVERVARATDGETVDLSVLRGQRMWFVDQIESSYRLRAVSAVGLRFPLNGTANGKAALAALDDAD
AEAALCRLDPMVAEGLRREIVEIRRTGIAFDRNEHTPGISAAAIARRALGDNVIAISVPAPTARFLEKEQRIIAALRAAA
DSPDWTR

Specific function: In conjunction with srpR represses the srpABC operon [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI87082359, Length=228, Percent_Identity=27.1929824561404, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1786468, Length=222, Percent_Identity=28.3783783783784, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1786715, Length=238, Percent_Identity=27.7310924369748, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 26633; Mature: 26502

Theoretical pI: Translated: 8.26; Mature: 8.26

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPTEGKSTTNRDEGIQVLRRAVAALDEIAAEPGHLRLVDLCERLGLAKSTTRRLLVGLV
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHH
EVGLVSVDSHGRFALGERLLGFGSVTGAHIAAAFRPTVERVARATDGETVDLSVLRGQRM
HHHEEEECCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCC
WFVDQIESSYRLRAVSAVGLRFPLNGTANGKAALAALDDADAEAALCRLDPMVAEGLRRE
HHHHHHCCHHHHHHHHHHCEECCCCCCCCCCEEEEECCCCCHHHHHHHHCHHHHHHHHHH
IVEIRRTGIAFDRNEHTPGISAAAIARRALGDNVIAISVPAPTARFLEKEQRIIAALRAA
HHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHH
ADSPDWTR
CCCCCCCC
>Mature Secondary Structure 
PPTEGKSTTNRDEGIQVLRRAVAALDEIAAEPGHLRLVDLCERLGLAKSTTRRLLVGLV
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHH
EVGLVSVDSHGRFALGERLLGFGSVTGAHIAAAFRPTVERVARATDGETVDLSVLRGQRM
HHHEEEECCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCC
WFVDQIESSYRLRAVSAVGLRFPLNGTANGKAALAALDDADAEAALCRLDPMVAEGLRRE
HHHHHHCCHHHHHHHHHHCEECCCCCCCCCCEEEEECCCCCHHHHHHHHCHHHHHHHHHH
IVEIRRTGIAFDRNEHTPGISAAAIARRALGDNVIAISVPAPTARFLEKEQRIIAALRAA
HHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHH
ADSPDWTR
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA