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The map label for this gene is infC [H]

Identifier: 148661437

GI number: 148661437

Start: 1853728

End: 1854396

Strand: Direct

Name: infC [H]

Synonym: MRA_1652

Alternate gene names: 148661437

Gene position: 1853728-1854396 (Clockwise)

Preceding gene: 148661433

Following gene: 148661438

Centisome position: 41.94

GC content: 62.63

Gene sequence:

>669_bases
CTGATTCCGGCCGGGTCCAACAAGCTGGTCGCGCCTGGAACAGCAGCCAACGAGGGAGGCCCCATCAGCACTGAAACCCG
CGTCAACGAGCGCATCCGCGTACCTGAAGTCCGATTGATCGGCCCAGGGGGGGAGCAGGTAGGCATTGTGCGTATCGAAG
ACGCACTTCGCGTCGCCGCGGACGCAGATCTCGACCTTGTCGAAGTTGCTCCCAATGCCAGACCGCCGGTCTGCAAGATC
ATGGACTACGGCAAGTACAAGTACGAGGCCGCGCAGAAGGCGCGCGAATCCCGCAGAAACCAACAGCAGACCGTCGTCAA
AGAACAAAAGCTGCGACCAAAGATTGACGATCACGATTACGAGACCAAAAAGGGTCACGTCGTCCGCTTCTTGGAGGCGG
GATCGAAGGTCAAGGTCACCATTATGTTCCGTGGACGTGAGCAGTCGCGGCCGGAGTTGGGCTATCGATTGCTGCAGCGG
CTGGGTGCGGACGTCGCCGATTACGGATTCATCGAGACGTCCGCCAAGCAGGACGGACGCAACATGACGATGGTGCTGGC
ACCGCACCGCGGTGCGAAGACCCGCGCTAGGGCCCGCCACCCGGGTGAACCGGCCGGCGGGCCGCCGCCCAAGCCCACGG
CCGGTGACAGCAAAGCCGCACCGAACTAG

Upstream 100 bases:

>100_bases
TGTTCTGCGTGCAGCGTGGGCGGCTTTGGCCGCGATCGGTCGGCATTGGGCCCTGCTTGTGCAGGGCTTTTTTTGCTGAT
GGTTTGGGTGTGTTCCCCAC

Downstream 100 bases:

>100_bases
CTCGCCAGCAAGACACGCAGAACCTAGAAATTCTAGAAATTGAGGAAACATGCCCAAGGCCAAGACCCACAGCGGGGCCT
CGAAGCGGTTCCGGCGCACC

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MIPAGSNKLVAPGTAANEGGPISTETRVNERIRVPEVRLIGPGGEQVGIVRIEDALRVAADADLDLVEVAPNARPPVCKI
MDYGKYKYEAAQKARESRRNQQQTVVKEQKLRPKIDDHDYETKKGHVVRFLEAGSKVKVTIMFRGREQSRPELGYRLLQR
LGADVADYGFIETSAKQDGRNMTMVLAPHRGAKTRARARHPGEPAGGPPPKPTAGDSKAAPN

Sequences:

>Translated_222_residues
MIPAGSNKLVAPGTAANEGGPISTETRVNERIRVPEVRLIGPGGEQVGIVRIEDALRVAADADLDLVEVAPNARPPVCKI
MDYGKYKYEAAQKARESRRNQQQTVVKEQKLRPKIDDHDYETKKGHVVRFLEAGSKVKVTIMFRGREQSRPELGYRLLQR
LGADVADYGFIETSAKQDGRNMTMVLAPHRGAKTRARARHPGEPAGGPPPKPTAGDSKAAPN
>Mature_222_residues
MIPAGSNKLVAPGTAANEGGPISTETRVNERIRVPEVRLIGPGGEQVGIVRIEDALRVAADADLDLVEVAPNARPPVCKI
MDYGKYKYEAAQKARESRRNQQQTVVKEQKLRPKIDDHDYETKKGHVVRFLEAGSKVKVTIMFRGREQSRPELGYRLLQR
LGADVADYGFIETSAKQDGRNMTMVLAPHRGAKTRARARHPGEPAGGPPPKPTAGDSKAAPN

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=166, Percent_Identity=46.3855421686747, Blast_Score=145, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 24250; Mature: 24250

Theoretical pI: Translated: 10.34; Mature: 10.34

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPAGSNKLVAPGTAANEGGPISTETRVNERIRVPEVRLIGPGGEQVGIVRIEDALRVAA
CCCCCCCEEECCCCCCCCCCCCCCHHHCCCEECCCEEEEECCCCCEEEEEEEHHHHHHHC
DADLDLVEVAPNARPPVCKIMDYGKYKYEAAQKARESRRNQQQTVVKEQKLRPKIDDHDY
CCCCEEEEECCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
ETKKGHVVRFLEAGSKVKVTIMFRGREQSRPELGYRLLQRLGADVADYGFIETSAKQDGR
CCCCCCEEEEEECCCEEEEEEEECCCCCCCHHHHHHHHHHHCCCHHHCCEEECCCCCCCC
NMTMVLAPHRGAKTRARARHPGEPAGGPPPKPTAGDSKAAPN
CEEEEEECCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MIPAGSNKLVAPGTAANEGGPISTETRVNERIRVPEVRLIGPGGEQVGIVRIEDALRVAA
CCCCCCCEEECCCCCCCCCCCCCCHHHCCCEECCCEEEEECCCCCEEEEEEEHHHHHHHC
DADLDLVEVAPNARPPVCKIMDYGKYKYEAAQKARESRRNQQQTVVKEQKLRPKIDDHDY
CCCCEEEEECCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
ETKKGHVVRFLEAGSKVKVTIMFRGREQSRPELGYRLLQRLGADVADYGFIETSAKQDGR
CCCCCCEEEEEECCCEEEEEEEECCCCCCCHHHHHHHHHHHCCCHHHCCEEECCCCCCCC
NMTMVLAPHRGAKTRARARHPGEPAGGPPPKPTAGDSKAAPN
CEEEEEECCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]