BacMap

Definition	Mycobacterium tuberculosis H37Ra, complete genome.
Accession	NC_009525
Length	4,419,977

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The map label for this gene is cya

Identifier: 148661420

GI number: 148661420

Start: 1828132

End: 1829463

Strand: Reverse

Name: cya

Synonym: MRA_1635

Alternate gene names: 148661420

Gene position: 1829463-1828132 (Counterclockwise)

Preceding gene: 148661422

Following gene: 148661419

Centisome position: 41.39

GC content: 65.47

Gene sequence:

>1332_bases
GTGGCGGCAAGAAAATGCGGCGCCCCACCGATAGCAGCGGATGGCTCGACACGACGCCCAGACTGTGTCACGGCCGTGCG
CACTCAGGCCCGCGCTCCCACGCAGCACTACGCCGAAAGCGTCGCGCGGCGGCAGCGCGTGCTTACCATCACCGCCTGGC
TCGCTGTCGTGGTAACCGGGAGCTTCGCGCTAATGCAACTAGCGACCGGGGCCGGGGGCTGGTACATCGCCCTGATCAAC
GTCTTCACCGCGGTTACTTTCGCGATCGTGCCCCTGCTACATCGCTTCGGGGGATTGGTGGCACCGCTTACGTTCATCGG
CACCGCCTATGTGGCGATCTTCGCCATCGGCTGGGATGTGGGCACCGACGCGGGTGCCCAGTTCTTCTTCTTGGTAGCCG
CCGCGTTGGTGGTGTTGCTGGTCGGCATCGAACACACCGCGTTAGCGGTGGGCCTAGCGGCGGTCGCCGCCGGTCTGGTG
ATTGCCCTGGAGTTCCTGGTCCCGCCCGATACTGGGCTTCAGCCGCCCTGGGCCATGTCGGTAAGTTTCGTCCTCACGAC
CGTCTCCGCCTGCGGGGTAGCGGTCGCAACGGTGTGGTTCGCGCTGCGTGATACTGCGCGCGCGGAGGCGGTCATGGAGG
CGGAGCACGACCGCTCCGAAGCACTGCTGGCCAACATGTTGCCGGCCAGCATCGCCGAGCGGCTTAAAGAACCCGAGCGA
AACATCATCGCCGATAAATACGACGAGGCCTCGGTGCTGTTCGCCGACATCGTCGGGTTCACCGAACGCGCCAGTAGCAC
CGCGCCGGCGGACCTGGTCCGGTTCCTGGACCGCCTCTACAGCGCTTTCGACGAGCTGGTCGACCAGCACGGGCTGGAGA
AAATCAAGGTCAGCGGGGACTCCTACATGGTTGTCAGCGGCGTTCCGCGGCCCCGGCCTGACCATACGCAAGCACTGGCG
GACTTTGCGCTCGACATGACCAATGTCGCAGCGCAATTGAAGGATCCACGCGGCAACCCGGTGCCGCTGCGGGTGGGCCT
GGCCACCGGCCCGGTGGTGGCGGGTGTGGTGGGTTCTCGACGGTTCTTCTACGACGTGTGGGGCGACGCGGTCAATGTCG
CGTCGCGGATGGAATCCACCGATTCGGTGGGGCAAATTCAGGTGCCAGACGAGGTTTACGAGCGTCTCAAGGACGACTTC
GTGTTGCGCGAGCGCGGCCACATAAACGTCAAGGGGAAAGGCGTAATGCGCACGTGGTACCTCATCGGCCGCAAGGTAGC
CGCAGATCCCGGCGAGGTGCGCGGGGCCGAACCCCGCACGGCAGGGGTCTGA

Upstream 100 bases:

>100_bases
TCCAGTGTGGGTTCGAATCCCACCGAGGGCACCAAGCGAACGCACCCGGAAAGCGCCGACAGAGTCGGTAAACGCTAACT
CACCGATTAGGCTTTAGTTC

Downstream 100 bases:

>100_bases
CCGCCAAGCGCTATCCCGGGGCCGCTACATGTGTCACACTGCGCCCATGGAACCAAGCCCTGTCGTGAGCCCTCTCCCAA
GGTTGTTGCCGCATCTCTGG

Product: membrane-anchored adenylyl cyclase Cya

Products: NA

Alternate protein names: ATP pyrophosphate-lyase; Adenylyl cyclase

Number of amino acids: Translated: 443; Mature: 442

Protein sequence:

>443_residues
MAARKCGAPPIAADGSTRRPDCVTAVRTQARAPTQHYAESVARRQRVLTITAWLAVVVTGSFALMQLATGAGGWYIALIN
VFTAVTFAIVPLLHRFGGLVAPLTFIGTAYVAIFAIGWDVGTDAGAQFFFLVAAALVVLLVGIEHTALAVGLAAVAAGLV
IALEFLVPPDTGLQPPWAMSVSFVLTTVSACGVAVATVWFALRDTARAEAVMEAEHDRSEALLANMLPASIAERLKEPER
NIIADKYDEASVLFADIVGFTERASSTAPADLVRFLDRLYSAFDELVDQHGLEKIKVSGDSYMVVSGVPRPRPDHTQALA
DFALDMTNVAAQLKDPRGNPVPLRVGLATGPVVAGVVGSRRFFYDVWGDAVNVASRMESTDSVGQIQVPDEVYERLKDDF
VLRERGHINVKGKGVMRTWYLIGRKVAADPGEVRGAEPRTAGV

Sequences:

>Translated_443_residues
MAARKCGAPPIAADGSTRRPDCVTAVRTQARAPTQHYAESVARRQRVLTITAWLAVVVTGSFALMQLATGAGGWYIALIN
VFTAVTFAIVPLLHRFGGLVAPLTFIGTAYVAIFAIGWDVGTDAGAQFFFLVAAALVVLLVGIEHTALAVGLAAVAAGLV
IALEFLVPPDTGLQPPWAMSVSFVLTTVSACGVAVATVWFALRDTARAEAVMEAEHDRSEALLANMLPASIAERLKEPER
NIIADKYDEASVLFADIVGFTERASSTAPADLVRFLDRLYSAFDELVDQHGLEKIKVSGDSYMVVSGVPRPRPDHTQALA
DFALDMTNVAAQLKDPRGNPVPLRVGLATGPVVAGVVGSRRFFYDVWGDAVNVASRMESTDSVGQIQVPDEVYERLKDDF
VLRERGHINVKGKGVMRTWYLIGRKVAADPGEVRGAEPRTAGV
>Mature_442_residues
AARKCGAPPIAADGSTRRPDCVTAVRTQARAPTQHYAESVARRQRVLTITAWLAVVVTGSFALMQLATGAGGWYIALINV
FTAVTFAIVPLLHRFGGLVAPLTFIGTAYVAIFAIGWDVGTDAGAQFFFLVAAALVVLLVGIEHTALAVGLAAVAAGLVI
ALEFLVPPDTGLQPPWAMSVSFVLTTVSACGVAVATVWFALRDTARAEAVMEAEHDRSEALLANMLPASIAERLKEPERN
IIADKYDEASVLFADIVGFTERASSTAPADLVRFLDRLYSAFDELVDQHGLEKIKVSGDSYMVVSGVPRPRPDHTQALAD
FALDMTNVAAQLKDPRGNPVPLRVGLATGPVVAGVVGSRRFFYDVWGDAVNVASRMESTDSVGQIQVPDEVYERLKDDFV
LRERGHINVKGKGVMRTWYLIGRKVAADPGEVRGAEPRTAGV

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 guanylate cyclase domain

Homologues:

Organism=Homo sapiens, GI4557257, Length=253, Percent_Identity=37.1541501976285, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI4580422, Length=224, Percent_Identity=38.8392857142857, Blast_Score=149, Evalue=6e-36,
Organism=Homo sapiens, GI167830411, Length=231, Percent_Identity=38.5281385281385, Blast_Score=145, Evalue=7e-35,
Organism=Homo sapiens, GI148536830, Length=243, Percent_Identity=37.8600823045267, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI134152694, Length=230, Percent_Identity=38.2608695652174, Blast_Score=143, Evalue=3e-34,
Organism=Homo sapiens, GI31083193, Length=197, Percent_Identity=36.0406091370558, Blast_Score=142, Evalue=8e-34,
Organism=Homo sapiens, GI115387102, Length=236, Percent_Identity=30.9322033898305, Blast_Score=135, Evalue=6e-32,
Organism=Homo sapiens, GI4504215, Length=234, Percent_Identity=35.8974358974359, Blast_Score=135, Evalue=1e-31,
Organism=Homo sapiens, GI24497587, Length=319, Percent_Identity=31.0344827586207, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI34486092, Length=218, Percent_Identity=36.2385321100917, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI4557255, Length=214, Percent_Identity=33.6448598130841, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI10181096, Length=228, Percent_Identity=34.6491228070175, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI10947061, Length=228, Percent_Identity=34.6491228070175, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI4504217, Length=225, Percent_Identity=36, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI222080083, Length=221, Percent_Identity=35.2941176470588, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI50959205, Length=225, Percent_Identity=36.4444444444444, Blast_Score=129, Evalue=4e-30,
Organism=Homo sapiens, GI194595478, Length=192, Percent_Identity=31.7708333333333, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI194595474, Length=192, Percent_Identity=31.7708333333333, Blast_Score=115, Evalue=7e-26,
Organism=Homo sapiens, GI194595476, Length=192, Percent_Identity=31.7708333333333, Blast_Score=115, Evalue=7e-26,
Organism=Homo sapiens, GI194595472, Length=192, Percent_Identity=31.7708333333333, Blast_Score=115, Evalue=7e-26,
Organism=Homo sapiens, GI67763816, Length=192, Percent_Identity=31.7708333333333, Blast_Score=115, Evalue=7e-26,
Organism=Homo sapiens, GI194595482, Length=187, Percent_Identity=31.0160427807487, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI4504211, Length=203, Percent_Identity=32.0197044334975, Blast_Score=110, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17534649, Length=240, Percent_Identity=37.0833333333333, Blast_Score=150, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI212659371, Length=225, Percent_Identity=39.1111111111111, Blast_Score=148, Evalue=5e-36,
Organism=Caenorhabditis elegans, GI86564713, Length=214, Percent_Identity=37.3831775700935, Blast_Score=148, Evalue=5e-36,
Organism=Caenorhabditis elegans, GI193206632, Length=226, Percent_Identity=37.1681415929204, Blast_Score=148, Evalue=5e-36,
Organism=Caenorhabditis elegans, GI17534659, Length=220, Percent_Identity=37.2727272727273, Blast_Score=147, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI17534653, Length=236, Percent_Identity=35.5932203389831, Blast_Score=147, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI17534657, Length=222, Percent_Identity=36.9369369369369, Blast_Score=146, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI71989822, Length=216, Percent_Identity=39.3518518518519, Blast_Score=145, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI17534651, Length=241, Percent_Identity=38.1742738589212, Blast_Score=145, Evalue=4e-35,
Organism=Caenorhabditis elegans, GI71989805, Length=216, Percent_Identity=39.3518518518519, Blast_Score=145, Evalue=4e-35,
Organism=Caenorhabditis elegans, GI193207841, Length=222, Percent_Identity=36.4864864864865, Blast_Score=145, Evalue=4e-35,
Organism=Caenorhabditis elegans, GI212645052, Length=232, Percent_Identity=37.0689655172414, Blast_Score=143, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI193206054, Length=226, Percent_Identity=36.283185840708, Blast_Score=140, Evalue=9e-34,
Organism=Caenorhabditis elegans, GI17534665, Length=228, Percent_Identity=35.9649122807018, Blast_Score=140, Evalue=9e-34,
Organism=Caenorhabditis elegans, GI71982300, Length=229, Percent_Identity=34.061135371179, Blast_Score=140, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI17561804, Length=235, Percent_Identity=35.7446808510638, Blast_Score=140, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17534655, Length=222, Percent_Identity=36.036036036036, Blast_Score=139, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI212645647, Length=240, Percent_Identity=34.5833333333333, Blast_Score=138, Evalue=6e-33,
Organism=Caenorhabditis elegans, GI71995305, Length=237, Percent_Identity=35.4430379746835, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17561794, Length=252, Percent_Identity=35.3174603174603, Blast_Score=137, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI193208534, Length=272, Percent_Identity=31.9852941176471, Blast_Score=134, Evalue=8e-32,
Organism=Caenorhabditis elegans, GI17561802, Length=228, Percent_Identity=36.8421052631579, Blast_Score=134, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17551720, Length=251, Percent_Identity=34.2629482071713, Blast_Score=133, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI17561800, Length=253, Percent_Identity=34.3873517786561, Blast_Score=132, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI71990146, Length=214, Percent_Identity=35.0467289719626, Blast_Score=131, Evalue=6e-31,
Organism=Caenorhabditis elegans, GI17568383, Length=220, Percent_Identity=38.6363636363636, Blast_Score=128, Evalue=6e-30,
Organism=Caenorhabditis elegans, GI71995893, Length=229, Percent_Identity=31.4410480349345, Blast_Score=127, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI71995895, Length=229, Percent_Identity=31.4410480349345, Blast_Score=127, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17561810, Length=214, Percent_Identity=34.1121495327103, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI71995899, Length=229, Percent_Identity=31.4410480349345, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17508769, Length=212, Percent_Identity=36.3207547169811, Blast_Score=125, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI71983004, Length=213, Percent_Identity=33.8028169014084, Blast_Score=125, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI115535133, Length=217, Percent_Identity=36.405529953917, Blast_Score=122, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI17557192, Length=217, Percent_Identity=31.7972350230415, Blast_Score=121, Evalue=9e-28,
Organism=Caenorhabditis elegans, GI193210669, Length=231, Percent_Identity=33.3333333333333, Blast_Score=121, Evalue=9e-28,
Organism=Caenorhabditis elegans, GI133931199, Length=227, Percent_Identity=31.7180616740088, Blast_Score=118, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI71994363, Length=224, Percent_Identity=33.9285714285714, Blast_Score=118, Evalue=7e-27,
Organism=Caenorhabditis elegans, GI32563954, Length=214, Percent_Identity=34.1121495327103, Blast_Score=116, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI212646197, Length=232, Percent_Identity=32.7586206896552, Blast_Score=115, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI193205840, Length=210, Percent_Identity=33.3333333333333, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI71995300, Length=184, Percent_Identity=35.3260869565217, Blast_Score=112, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI71985505, Length=232, Percent_Identity=26.7241379310345, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71996442, Length=234, Percent_Identity=29.9145299145299, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI71983333, Length=215, Percent_Identity=24.1860465116279, Blast_Score=78, Evalue=9e-15,
Organism=Drosophila melanogaster, GI161078020, Length=223, Percent_Identity=40.3587443946188, Blast_Score=169, Evalue=5e-42,
Organism=Drosophila melanogaster, GI85725044, Length=249, Percent_Identity=37.3493975903614, Blast_Score=163, Evalue=2e-40,
Organism=Drosophila melanogaster, GI116008008, Length=217, Percent_Identity=39.1705069124424, Blast_Score=163, Evalue=2e-40,
Organism=Drosophila melanogaster, GI62484298, Length=217, Percent_Identity=39.1705069124424, Blast_Score=163, Evalue=2e-40,
Organism=Drosophila melanogaster, GI62484477, Length=217, Percent_Identity=39.1705069124424, Blast_Score=163, Evalue=2e-40,
Organism=Drosophila melanogaster, GI281366459, Length=225, Percent_Identity=37.3333333333333, Blast_Score=146, Evalue=3e-35,
Organism=Drosophila melanogaster, GI281366457, Length=225, Percent_Identity=37.3333333333333, Blast_Score=146, Evalue=3e-35,
Organism=Drosophila melanogaster, GI281366455, Length=225, Percent_Identity=37.3333333333333, Blast_Score=146, Evalue=3e-35,
Organism=Drosophila melanogaster, GI56292422, Length=225, Percent_Identity=37.3333333333333, Blast_Score=146, Evalue=3e-35,
Organism=Drosophila melanogaster, GI56292424, Length=225, Percent_Identity=37.3333333333333, Blast_Score=146, Evalue=3e-35,
Organism=Drosophila melanogaster, GI24666940, Length=225, Percent_Identity=37.3333333333333, Blast_Score=146, Evalue=3e-35,
Organism=Drosophila melanogaster, GI28574512, Length=221, Percent_Identity=37.5565610859729, Blast_Score=145, Evalue=7e-35,
Organism=Drosophila melanogaster, GI161076872, Length=221, Percent_Identity=37.5565610859729, Blast_Score=144, Evalue=9e-35,
Organism=Drosophila melanogaster, GI221330468, Length=238, Percent_Identity=35.7142857142857, Blast_Score=142, Evalue=4e-34,
Organism=Drosophila melanogaster, GI221330470, Length=238, Percent_Identity=35.7142857142857, Blast_Score=142, Evalue=5e-34,
Organism=Drosophila melanogaster, GI24663843, Length=223, Percent_Identity=36.322869955157, Blast_Score=140, Evalue=1e-33,
Organism=Drosophila melanogaster, GI24663839, Length=223, Percent_Identity=36.322869955157, Blast_Score=140, Evalue=1e-33,
Organism=Drosophila melanogaster, GI24585694, Length=249, Percent_Identity=34.136546184739, Blast_Score=136, Evalue=3e-32,
Organism=Drosophila melanogaster, GI281366320, Length=243, Percent_Identity=32.0987654320988, Blast_Score=135, Evalue=4e-32,
Organism=Drosophila melanogaster, GI24651577, Length=224, Percent_Identity=35.7142857142857, Blast_Score=135, Evalue=5e-32,
Organism=Drosophila melanogaster, GI161084260, Length=230, Percent_Identity=36.5217391304348, Blast_Score=135, Evalue=5e-32,
Organism=Drosophila melanogaster, GI24647268, Length=215, Percent_Identity=37.6744186046512, Blast_Score=133, Evalue=3e-31,
Organism=Drosophila melanogaster, GI24642014, Length=247, Percent_Identity=35.6275303643725, Blast_Score=131, Evalue=8e-31,
Organism=Drosophila melanogaster, GI24667100, Length=239, Percent_Identity=30.9623430962343, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI62473752, Length=180, Percent_Identity=37.7777777777778, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI17137448, Length=180, Percent_Identity=37.7777777777778, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI281366555, Length=313, Percent_Identity=28.7539936102236, Blast_Score=116, Evalue=2e-26,
Organism=Drosophila melanogaster, GI21355729, Length=264, Percent_Identity=31.0606060606061, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI116008022, Length=262, Percent_Identity=30.9160305343511, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI116008024, Length=262, Percent_Identity=30.9160305343511, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24655923, Length=296, Percent_Identity=22.2972972972973, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI281365509, Length=211, Percent_Identity=27.0142180094787, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI281365507, Length=211, Percent_Identity=27.0142180094787, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI281365511, Length=245, Percent_Identity=26.530612244898, Blast_Score=105, Evalue=8e-23,
Organism=Drosophila melanogaster, GI19921208, Length=189, Percent_Identity=27.5132275132275, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24583980, Length=378, Percent_Identity=24.0740740740741, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24583978, Length=193, Percent_Identity=29.5336787564767, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24583976, Length=204, Percent_Identity=25.4901960784314, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24651096, Length=182, Percent_Identity=34.0659340659341, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI85724938, Length=191, Percent_Identity=25.130890052356, Blast_Score=89, Evalue=8e-18,
Organism=Drosophila melanogaster, GI221330384, Length=116, Percent_Identity=37.0689655172414, Blast_Score=87, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CYA1_MYCBO (P0A4Y1)

Other databases:

- EMBL:   BX248339
- RefSeq:   NP_855304.1
- ProteinModelPortal:   P0A4Y1
- SMR:   P0A4Y1
- EnsemblBacteria:   EBMYCT00000017247
- GeneID:   1092586
- GenomeReviews:   BX248333_GR
- KEGG:   mbo:Mb1651c
- GeneTree:   EBGT00050000015402
- HOGENOM:   HBG564705
- ProtClustDB:   CLSK799821
- BioCyc:   MBOV233413:MB1651C-MONOMER
- BRENDA:   4.6.1.1
- InterPro:   IPR001054
- InterPro:   IPR018297
- Gene3D:   G3DSA:3.30.70.1230
- SMART:   SM00044

Pfam domain/function: PF00211 Guanylate_cyc; SSF55073 A/G_cyclase

EC number: =4.6.1.1

Molecular weight: Translated: 47370; Mature: 47239

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: PS00452 GUANYLATE_CYCLASE_1; PS50125 GUANYLATE_CYCLASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1e3db314)-; HASH(0x1e6ca784)-; HASH(0x1e941c50)-; HASH(0x1ea8a590)-; HASH(0x1e68b240)-; HASH(0x1e95249c)-;

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAARKCGAPPIAADGSTRRPDCVTAVRTQARAPTQHYAESVARRQRVLTITAWLAVVVTG
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
SFALMQLATGAGGWYIALINVFTAVTFAIVPLLHRFGGLVAPLTFIGTAYVAIFAIGWDV
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCC
GTDAGAQFFFLVAAALVVLLVGIEHTALAVGLAAVAAGLVIALEFLVPPDTGLQPPWAMS
CCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
VSFVLTTVSACGVAVATVWFALRDTARAEAVMEAEHDRSEALLANMLPASIAERLKEPER
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCH
NIIADKYDEASVLFADIVGFTERASSTAPADLVRFLDRLYSAFDELVDQHGLEKIKVSGD
HCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCC
SYMVVSGVPRPRPDHTQALADFALDMTNVAAQLKDPRGNPVPLRVGLATGPVVAGVVGSR
CEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHCCC
RFFYDVWGDAVNVASRMESTDSVGQIQVPDEVYERLKDDFVLRERGHINVKGKGVMRTWY
HHHHHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHEECCCCEEEECCCCHHHHHH
LIGRKVAADPGEVRGAEPRTAGV
HHCCHHCCCCCCCCCCCCCCCCH
>Mature Secondary Structure 
AARKCGAPPIAADGSTRRPDCVTAVRTQARAPTQHYAESVARRQRVLTITAWLAVVVTG
CCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
SFALMQLATGAGGWYIALINVFTAVTFAIVPLLHRFGGLVAPLTFIGTAYVAIFAIGWDV
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCC
GTDAGAQFFFLVAAALVVLLVGIEHTALAVGLAAVAAGLVIALEFLVPPDTGLQPPWAMS
CCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
VSFVLTTVSACGVAVATVWFALRDTARAEAVMEAEHDRSEALLANMLPASIAERLKEPER
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCH
NIIADKYDEASVLFADIVGFTERASSTAPADLVRFLDRLYSAFDELVDQHGLEKIKVSGD
HCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCC
SYMVVSGVPRPRPDHTQALADFALDMTNVAAQLKDPRGNPVPLRVGLATGPVVAGVVGSR
CEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHCCC
RFFYDVWGDAVNVASRMESTDSVGQIQVPDEVYERLKDDFVLRERGHINVKGKGVMRTWY
HHHHHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHEECCCCEEEECCCCHHHHHH
LIGRKVAADPGEVRGAEPRTAGV
HHCCHHCCCCCCCCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12788972