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The map label for this gene is 148661387

Identifier: 148661387

GI number: 148661387

Start: 1793918

End: 1795258

Strand: Reverse

Name: 148661387

Synonym: MRA_1602

Alternate gene names: NA

Gene position: 1795258-1793918 (Counterclockwise)

Preceding gene: 148661388

Following gene: 148661383

Centisome position: 40.62

GC content: 64.88

Gene sequence:

>1341_bases
ATGGTAGAGCCCGGCAATTTGGCAGGCGCGACCGGCGCCGAATGGATCGGCCGGCCACCGCACGAGGAATTGCAGCGCAA
AGTGCGCCCGCTGCTGCCATCCGACGATCCGTTCTACTTCCCACCTGCCGGCTACCAGCATGCCGTGCCCGGAACGGTGT
TGCGCTCGCGCGATGTCGAACTGGCGTTTATGGGCTTGATTCCGCAGCCCGTCACCGCTACCCAGCTGCTGTACCGGACC
ACGAACATGTACGGCAACCCCGAGGCGACGGTGACCACGGTGATCGTCCCAGCGGAGCTTGCCCCGGGTCAGACCTGCCC
CTTGCTGTCGTACCAGTGTGCGATCGATGCCATGTCGTCGCGCTGTTTTCCGTCATATGCCCTGCGACGACGGGCCAAGG
CCCTGGGGTCACTGACCCAAATGGAGCTGTTGATGATCAGCGCCGCACTTGCCGAAGGATGGGCGGTATCAGTACCCGAC
CATGAAGGGCCGAAAGGGCTGTGGGGGTCGCCGTATGAACCCGGTTACCGAGTCCTCGACGGAATCCGGGCTGCCTTGAA
TTCCGAGCGTGTCGGGTTGTCCCCGGCAACGCCGATCGGGCTGTGGGGCTACTCCGGCGGCGGGCTGGCCAGCGCGTGGG
CCGCCGAAGCATGCGGCGAGTACGCACCGGACCTAGACATCGTCGGCGCCGTGCTGGGATCACCCGTCGGTGACCTTGGT
CACACGTTCCGCCGGCTCAATGGCACTCTTCTTGCCGGTCTGCCCGCGTTGGTGGTGGCCGCGCTGCAACACAGCTACCC
CGGCCTGGCCCGGGTGATCAAGGAGCACGCCAACGACGAAGGACGTCAGCTGCTGGAGCAACTGACGGAGATGACAACGG
TAGACGCAGTGATCCGGATGGCCGGCAGGGACATGGGTGACTTCCTCGACGAACCCCTTGAGGACATTCTGTCGACGCCG
GAAATTTCCCATGTCTTCGGCGACACCAAGCTGGGTAGCGCGGTGCCCACCCCGCCGGTATTGATCGTGCAGGCCGTGCA
TGACTACCTCATCGACGTCTCTGACATCGACGCGCTCGCTGACAGCTATACAGCCGGCGGCGCCAACGTCACCTACCACC
GCGACCTGTTCAGCGAACATGTGTCCCTGCACCCGCTGTCGGCCCCAATGACGCTTCGCTGGCTCACCGACCGGTTCGCC
GGCAAGCCACTGACCGACCACCGCGTCCGGACCACGTGGCCGACCATCTTCAACCCGATGACCTACGCCGGCATGGCGAG
ACTGGCCGTGATCGCGGCCAAGGTGATCACCGGCAGGAAGTTGAGCCGCCGTCCGCTCTGA

Upstream 100 bases:

>100_bases
CCTTGAGTGCCGGCGCTGAACTGCGACAGGCAAACCGCGCTGCTACCCCGTCAGGGACCGATCACGCGCGAGGATGCCGG
ATGGCCATGAAGGGAGCCTA

Downstream 100 bases:

>100_bases
CCTGGCCAATGCGCTCTGCGCATACCGGCGCGAACTCGGACCTGGCACACAACCTCGTCACGCCAGACTTAAACCAGTTC
GACGATCTGCCGCTTGAATC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 446; Mature: 446

Protein sequence:

>446_residues
MVEPGNLAGATGAEWIGRPPHEELQRKVRPLLPSDDPFYFPPAGYQHAVPGTVLRSRDVELAFMGLIPQPVTATQLLYRT
TNMYGNPEATVTTVIVPAELAPGQTCPLLSYQCAIDAMSSRCFPSYALRRRAKALGSLTQMELLMISAALAEGWAVSVPD
HEGPKGLWGSPYEPGYRVLDGIRAALNSERVGLSPATPIGLWGYSGGGLASAWAAEACGEYAPDLDIVGAVLGSPVGDLG
HTFRRLNGTLLAGLPALVVAALQHSYPGLARVIKEHANDEGRQLLEQLTEMTTVDAVIRMAGRDMGDFLDEPLEDILSTP
EISHVFGDTKLGSAVPTPPVLIVQAVHDYLIDVSDIDALADSYTAGGANVTYHRDLFSEHVSLHPLSAPMTLRWLTDRFA
GKPLTDHRVRTTWPTIFNPMTYAGMARLAVIAAKVITGRKLSRRPL

Sequences:

>Translated_446_residues
MVEPGNLAGATGAEWIGRPPHEELQRKVRPLLPSDDPFYFPPAGYQHAVPGTVLRSRDVELAFMGLIPQPVTATQLLYRT
TNMYGNPEATVTTVIVPAELAPGQTCPLLSYQCAIDAMSSRCFPSYALRRRAKALGSLTQMELLMISAALAEGWAVSVPD
HEGPKGLWGSPYEPGYRVLDGIRAALNSERVGLSPATPIGLWGYSGGGLASAWAAEACGEYAPDLDIVGAVLGSPVGDLG
HTFRRLNGTLLAGLPALVVAALQHSYPGLARVIKEHANDEGRQLLEQLTEMTTVDAVIRMAGRDMGDFLDEPLEDILSTP
EISHVFGDTKLGSAVPTPPVLIVQAVHDYLIDVSDIDALADSYTAGGANVTYHRDLFSEHVSLHPLSAPMTLRWLTDRFA
GKPLTDHRVRTTWPTIFNPMTYAGMARLAVIAAKVITGRKLSRRPL
>Mature_446_residues
MVEPGNLAGATGAEWIGRPPHEELQRKVRPLLPSDDPFYFPPAGYQHAVPGTVLRSRDVELAFMGLIPQPVTATQLLYRT
TNMYGNPEATVTTVIVPAELAPGQTCPLLSYQCAIDAMSSRCFPSYALRRRAKALGSLTQMELLMISAALAEGWAVSVPD
HEGPKGLWGSPYEPGYRVLDGIRAALNSERVGLSPATPIGLWGYSGGGLASAWAAEACGEYAPDLDIVGAVLGSPVGDLG
HTFRRLNGTLLAGLPALVVAALQHSYPGLARVIKEHANDEGRQLLEQLTEMTTVDAVIRMAGRDMGDFLDEPLEDILSTP
EISHVFGDTKLGSAVPTPPVLIVQAVHDYLIDVSDIDALADSYTAGGANVTYHRDLFSEHVSLHPLSAPMTLRWLTDRFA
GKPLTDHRVRTTWPTIFNPMTYAGMARLAVIAAKVITGRKLSRRPL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. Lipase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y1592_MYCTU (O06598)

Other databases:

- EMBL:   BX842577
- EMBL:   AE000516
- PIR:   B70543
- RefSeq:   NP_216108.1
- RefSeq:   NP_336082.1
- ProteinModelPortal:   O06598
- SMR:   O06598
- EnsemblBacteria:   EBMYCT00000000864
- EnsemblBacteria:   EBMYCT00000068992
- GeneID:   886287
- GeneID:   924299
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT1628
- KEGG:   mtu:Rv1592c
- TIGR:   MT1628
- TubercuList:   Rv1592c
- GeneTree:   EBGT00050000015595
- HOGENOM:   HBG669319
- OMA:   SEHLLLH
- ProtClustDB:   CLSK791271
- InterPro:   IPR005152

Pfam domain/function: PF03583 LIP

EC number: NA

Molecular weight: Translated: 48044; Mature: 48044

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVEPGNLAGATGAEWIGRPPHEELQRKVRPLLPSDDPFYFPPAGYQHAVPGTVLRSRDVE
CCCCCCCCCCCCCHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCC
LAFMGLIPQPVTATQLLYRTTNMYGNPEATVTTVIVPAELAPGQTCPLLSYQCAIDAMSS
EEEECCCCCCHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHH
RCFPSYALRRRAKALGSLTQMELLMISAALAEGWAVSVPDHEGPKGLWGSPYEPGYRVLD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCHHHHHH
GIRAALNSERVGLSPATPIGLWGYSGGGLASAWAAEACGEYAPDLDIVGAVLGSPVGDLG
HHHHHHCCCCCCCCCCCCCEECCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHH
HTFRRLNGTLLAGLPALVVAALQHSYPGLARVIKEHANDEGRQLLEQLTEMTTVDAVIRM
HHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
AGRDMGDFLDEPLEDILSTPEISHVFGDTKLGSAVPTPPVLIVQAVHDYLIDVSDIDALA
HCCCHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHH
DSYTAGGANVTYHRDLFSEHVSLHPLSAPMTLRWLTDRFAGKPLTDHRVRTTWPTIFNPM
HHCCCCCCCEEEHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHCCH
TYAGMARLAVIAAKVITGRKLSRRPL
HHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MVEPGNLAGATGAEWIGRPPHEELQRKVRPLLPSDDPFYFPPAGYQHAVPGTVLRSRDVE
CCCCCCCCCCCCCHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCC
LAFMGLIPQPVTATQLLYRTTNMYGNPEATVTTVIVPAELAPGQTCPLLSYQCAIDAMSS
EEEECCCCCCHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHH
RCFPSYALRRRAKALGSLTQMELLMISAALAEGWAVSVPDHEGPKGLWGSPYEPGYRVLD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCHHHHHH
GIRAALNSERVGLSPATPIGLWGYSGGGLASAWAAEACGEYAPDLDIVGAVLGSPVGDLG
HHHHHHCCCCCCCCCCCCCEECCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHH
HTFRRLNGTLLAGLPALVVAALQHSYPGLARVIKEHANDEGRQLLEQLTEMTTVDAVIRM
HHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
AGRDMGDFLDEPLEDILSTPEISHVFGDTKLGSAVPTPPVLIVQAVHDYLIDVSDIDALA
HCCCHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHH
DSYTAGGANVTYHRDLFSEHVSLHPLSAPMTLRWLTDRFAGKPLTDHRVRTTWPTIFNPM
HHCCCCCCCEEEHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHCCH
TYAGMARLAVIAAKVITGRKLSRRPL
HHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036