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The map label for this gene is perM [C]

Identifier: 148660887

GI number: 148660887

Start: 1230701

End: 1231858

Strand: Reverse

Name: perM [C]

Synonym: MRA_1112

Alternate gene names: 148660887

Gene position: 1231858-1230701 (Counterclockwise)

Preceding gene: 148660888

Following gene: 148660885

Centisome position: 27.87

GC content: 61.92

Gene sequence:

>1158_bases
TTGAACACCGAATTCACGCTCACTCAGAAGCGCGCCCTGGCGATCCTCACGTTGATCGCTTTGCTGTTCGGTGCGTACTT
CCTGCGTAACTATTTCGTTCTGATCGTGGTGGCAGCCGTCGGCGCCTATTTGTTCACGCCACTTTTCAAGTGGTTCACCA
AGCGCTTCAATACCGGCCTGTCGGCCGCCTGCACGTTGTTGTCGGCGCTGGCCGCCGTCGTCGTGCCGGTGGGAGCCTTG
GTGGGGCTGGCGATCGTGCAGATCGCTCGCATGGTCGACTCCGTCGCCGACTGGGTGCGGACGACCGATCTGAGCACCCT
CGGCGACAAGATCCTGCAATTCGTCAACGGCTTGTTTGACCGGGTGCCGTTCCTGCACATCACGGTTACCGCGGACGCAC
TGCGCAAAGCGATGATTTCGGTAGCACAGAACGTCGGCGAATGGCTGCTGCACTTCCTGCGCGACGCCGCCGGAAGCCTC
GCCGGTGTCATCACGTCGGCCATCATCTTTGTGTACGTGTTCGTCGCGCTCTTGGTGAACCGCGAGAAGCTAAGGACACT
GATCGGCCAGCTCAACCCGCTCGGCGAAGACGTCACGGATCTGTACCTGCAGAAGATGGGCTCGATGGTCCGCGGCACGG
TGAACGGCCAGTTCGTCATCGCGGCGTGCCAGGGAGTCGCCGGCGCCGCATCGATCTACATCGCCGGATTTCACCACGGC
TTCTTCATCTTCGCCATCGTGCTCACCGCGTTGTCGATCATCCCGCTGGGCGGCGGCATCGTGACGATTCCGTTCGGCAT
CGGGATGATCTTCTACGGCAATATCGCCGGGGGAATCTTCGTGCTGCTGTGGCATCTGCTGGTGGTTACCAACATCGACA
ACGTCCTGCGGCCGATCCTGGTGCCGCGCGACGCGCGGCTGAACTCGGCGCTGATGTTGCTGTCGGTGTTCGCCGGTATC
ACCATGTTCGGCCCCTGGGGTATCATCATCGGCCCGGTGCTGATGATCCTCATCGTCACCACCATCGACGTCTACCTCGC
GGTGTACAAAGGCGTCGAACTGGAACAGTTCGAAGCACCACCCGTCCGCCGCAGGTGGCTGCCGCGTCGAGGCCCGGCCA
CGTCAAGAAACGCCCCGCCTCCGTCAACCGCTGAGTGA

Upstream 100 bases:

>100_bases
TGCACCGACATCCGTTGACTCTGCATCCACCACGCAATAGTGCGAGTAACCCGCCTGCTGGACGCAGAGTCAGCACCAAG
AAGCGAAGGGCGGACCCGCT

Downstream 100 bases:

>100_bases
GACCCGCTATCGTGCGGGCAACGGGGGCTGCGATTGCGTCGCCGACGCCAGCGTGCGGAACTGATCGATGCTGCCGGCAC
CGGTGATTGCCAGCTGGGTG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MNTEFTLTQKRALAILTLIALLFGAYFLRNYFVLIVVAAVGAYLFTPLFKWFTKRFNTGLSAACTLLSALAAVVVPVGAL
VGLAIVQIARMVDSVADWVRTTDLSTLGDKILQFVNGLFDRVPFLHITVTADALRKAMISVAQNVGEWLLHFLRDAAGSL
AGVITSAIIFVYVFVALLVNREKLRTLIGQLNPLGEDVTDLYLQKMGSMVRGTVNGQFVIAACQGVAGAASIYIAGFHHG
FFIFAIVLTALSIIPLGGGIVTIPFGIGMIFYGNIAGGIFVLLWHLLVVTNIDNVLRPILVPRDARLNSALMLLSVFAGI
TMFGPWGIIIGPVLMILIVTTIDVYLAVYKGVELEQFEAPPVRRRWLPRRGPATSRNAPPPSTAE

Sequences:

>Translated_385_residues
MNTEFTLTQKRALAILTLIALLFGAYFLRNYFVLIVVAAVGAYLFTPLFKWFTKRFNTGLSAACTLLSALAAVVVPVGAL
VGLAIVQIARMVDSVADWVRTTDLSTLGDKILQFVNGLFDRVPFLHITVTADALRKAMISVAQNVGEWLLHFLRDAAGSL
AGVITSAIIFVYVFVALLVNREKLRTLIGQLNPLGEDVTDLYLQKMGSMVRGTVNGQFVIAACQGVAGAASIYIAGFHHG
FFIFAIVLTALSIIPLGGGIVTIPFGIGMIFYGNIAGGIFVLLWHLLVVTNIDNVLRPILVPRDARLNSALMLLSVFAGI
TMFGPWGIIIGPVLMILIVTTIDVYLAVYKGVELEQFEAPPVRRRWLPRRGPATSRNAPPPSTAE
>Mature_385_residues
MNTEFTLTQKRALAILTLIALLFGAYFLRNYFVLIVVAAVGAYLFTPLFKWFTKRFNTGLSAACTLLSALAAVVVPVGAL
VGLAIVQIARMVDSVADWVRTTDLSTLGDKILQFVNGLFDRVPFLHITVTADALRKAMISVAQNVGEWLLHFLRDAAGSL
AGVITSAIIFVYVFVALLVNREKLRTLIGQLNPLGEDVTDLYLQKMGSMVRGTVNGQFVIAACQGVAGAASIYIAGFHHG
FFIFAIVLTALSIIPLGGGIVTIPFGIGMIFYGNIAGGIFVLLWHLLVVTNIDNVLRPILVPRDARLNSALMLLSVFAGI
TMFGPWGIIIGPVLMILIVTTIDVYLAVYKGVELEQFEAPPVRRRWLPRRGPATSRNAPPPSTAE

Specific function: Unknown

COG id: COG0628

COG function: function code R; Predicted permease

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0118 (perM) family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y1101_MYCTU (O53449)

Other databases:

- EMBL:   BX842575
- EMBL:   AE000516
- PIR:   C70897
- RefSeq:   NP_215617.1
- RefSeq:   NP_335577.1
- EnsemblBacteria:   EBMYCT00000001983
- EnsemblBacteria:   EBMYCT00000070378
- GeneID:   885482
- GeneID:   924968
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT1133
- KEGG:   mtu:Rv1101c
- TIGR:   MT1133
- TubercuList:   Rv1101c
- GeneTree:   EBGT00050000017084
- HOGENOM:   HBG565128
- OMA:   ITVILEG
- ProtClustDB:   CLSK790949
- InterPro:   IPR002549
- PANTHER:   PTHR21716

Pfam domain/function: PF01594 UPF0118

EC number: NA

Molecular weight: Translated: 41717; Mature: 41717

Theoretical pI: Translated: 9.99; Mature: 9.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1d9e53b8)-; HASH(0x1d03b994)-; HASH(0x1d74bdac)-; HASH(0x1dbb1950)-; HASH(0x1db0f860)-; HASH(0x1d7dc954)-; HASH(0x1c561378)-; HASH(0x1ce6686c)-;

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CHHHHCCCCCCCCCCCCCCCCCCCH
>Mature Secondary Structure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CHHHHCCCCCCCCCCCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036