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The map label for this gene is pra

Identifier: 148660863

GI number: 148660863

Start: 1204622

End: 1205344

Strand: Direct

Name: pra

Synonym: MRA_1088

Alternate gene names: 148660863

Gene position: 1204622-1205344 (Clockwise)

Preceding gene: 148660862

Following gene: 148660864

Centisome position: 27.25

GC content: 66.25

Gene sequence:

>723_bases
ATGACCGAACAGCCGCCCCCCGGCGGGTCGTACCCACCGCCCCCGCCACCGCCTGGGCCGTCCGGTGGGCATGAGCCACC
TCCCGCTGCACCACCCGGCGGCAGTGGTTACGCTCCGCCCCCTCCGCCCTCGAGCGGCAGTGGCTACCCGCCTCCGCCGC
CACCGCCTGGCGGGGGGGCCTACCCGCCGCCTCCGCCGTCGGCCGGCGGTTACGCGCCGCCGCCGCCCGGACCGGCGATT
CGTACGATGCCGACCGAGTCCTACACGCCGTGGATTACCCGGGTGCTGGCGGCATTCATCGACTGGGCCCCATACGTAGT
GCTGGTTGGCATCGGTTGGGTGATCATGCTGGTCACTCAGACGTCGTCGTGCGTCACCAGCATTAGTGAGTACGACGTCG
GCCAGTTCTGCGTTTCCCAGCCGTCGATGATCGGCCAGTTGGTGCAGTGGTTGTTGTCGGTGGGCGGATTGGCTTACCTG
GTCTGGAACTACGGCTATCGCCAGGGCACCATCGGGTCGAGCATCGGCAAGTCGGTGCTGAAGTTCAAGGTGGTCAGCGA
GACCACCGGGCAACCAATCGGCTTCGGGATGTCGGTGGTACGCCAGCTTGCCCACTTTATCGACGCGATCATCTGCTTCG
TCGGGTTCCTGTTTCCGCTGTGGGACGCTAAACGGCAAACGTTGGCGGACAAGATCATGACGACGGTGTGCGTGCCGATC
TGA

Upstream 100 bases:

>100_bases
CTCATCTCACCGCCGGGCGTTCCGGTGAATCCGGTCCTCAGGTACTGTAGTCCCGCCTAGTTCACCCTAGTTCAGCTGAA
CCTCAGTGGAAGGTGTGCCC

Downstream 100 bases:

>100_bases
TCCGGGACTGCACTGCCCACCCGACCGTCCGATGAGCGAAGACCGCACGGGACACCAGGGAATCAGCGGACCGGCCACCC
GCGCCATCCACGCTGGCTAC

Product: putative proline rich antigen-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 240; Mature: 239

Protein sequence:

>240_residues
MTEQPPPGGSYPPPPPPPGPSGGHEPPPAAPPGGSGYAPPPPPSSGSGYPPPPPPPGGGAYPPPPPSAGGYAPPPPGPAI
RTMPTESYTPWITRVLAAFIDWAPYVVLVGIGWVIMLVTQTSSCVTSISEYDVGQFCVSQPSMIGQLVQWLLSVGGLAYL
VWNYGYRQGTIGSSIGKSVLKFKVVSETTGQPIGFGMSVVRQLAHFIDAIICFVGFLFPLWDAKRQTLADKIMTTVCVPI

Sequences:

>Translated_240_residues
MTEQPPPGGSYPPPPPPPGPSGGHEPPPAAPPGGSGYAPPPPPSSGSGYPPPPPPPGGGAYPPPPPSAGGYAPPPPGPAI
RTMPTESYTPWITRVLAAFIDWAPYVVLVGIGWVIMLVTQTSSCVTSISEYDVGQFCVSQPSMIGQLVQWLLSVGGLAYL
VWNYGYRQGTIGSSIGKSVLKFKVVSETTGQPIGFGMSVVRQLAHFIDAIICFVGFLFPLWDAKRQTLADKIMTTVCVPI
>Mature_239_residues
TEQPPPGGSYPPPPPPPGPSGGHEPPPAAPPGGSGYAPPPPPSSGSGYPPPPPPPGGGAYPPPPPSAGGYAPPPPGPAIR
TMPTESYTPWITRVLAAFIDWAPYVVLVGIGWVIMLVTQTSSCVTSISEYDVGQFCVSQPSMIGQLVQWLLSVGGLAYLV
WNYGYRQGTIGSSIGKSVLKFKVVSETTGQPIGFGMSVVRQLAHFIDAIICFVGFLFPLWDAKRQTLADKIMTTVCVPI

Specific function: Unknown

COG id: COG1714

COG function: function code S; Predicted membrane protein/domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To M.leprae PRA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PRA_MYCTU (O53426)

Other databases:

- EMBL:   BX842575
- EMBL:   AE000516
- PIR:   D70894
- RefSeq:   NP_215594.1
- RefSeq:   NP_335551.1
- ProteinModelPortal:   O53426
- EnsemblBacteria:   EBMYCT00000001301
- EnsemblBacteria:   EBMYCT00000071052
- GeneID:   887111
- GeneID:   925066
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT1109
- KEGG:   mtu:Rv1078
- TIGR:   MT1109
- TubercuList:   Rv1078
- GeneTree:   EBGT00050000014860
- HOGENOM:   HBG751082
- OMA:   MKFKVVS
- ProtClustDB:   CLSK790936
- InterPro:   IPR010432

Pfam domain/function: PF06271 RDD

EC number: NA

Molecular weight: Translated: 25076; Mature: 24945

Theoretical pI: Translated: 7.28; Mature: 7.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEQPPPGGSYPPPPPPPGPSGGHEPPPAAPPGGSGYAPPPPPSSGSGYPPPPPPPGGGA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
YPPPPPSAGGYAPPPPGPAIRTMPTESYTPWITRVLAAFIDWAPYVVLVGIGWVIMLVTQ
CCCCCCCCCCCCCCCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TSSCVTSISEYDVGQFCVSQPSMIGQLVQWLLSVGGLAYLVWNYGYRQGTIGSSIGKSVL
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
KFKVVSETTGQPIGFGMSVVRQLAHFIDAIICFVGFLFPLWDAKRQTLADKIMTTVCVPI
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TEQPPPGGSYPPPPPPPGPSGGHEPPPAAPPGGSGYAPPPPPSSGSGYPPPPPPPGGGA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
YPPPPPSAGGYAPPPPGPAIRTMPTESYTPWITRVLAAFIDWAPYVVLVGIGWVIMLVTQ
CCCCCCCCCCCCCCCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TSSCVTSISEYDVGQFCVSQPSMIGQLVQWLLSVGGLAYLVWNYGYRQGTIGSSIGKSVL
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
KFKVVSETTGQPIGFGMSVVRQLAHFIDAIICFVGFLFPLWDAKRQTLADKIMTTVCVPI
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036