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The map label for this gene is tatD [H]

Identifier: 148660790

GI number: 148660790

Start: 1128397

End: 1129191

Strand: Direct

Name: tatD [H]

Synonym: MRA_1017

Alternate gene names: 148660790

Gene position: 1128397-1129191 (Clockwise)

Preceding gene: 148660788

Following gene: 148660791

Centisome position: 25.53

GC content: 68.3

Gene sequence:

>795_bases
TTGGTCGACGCCCACACCCATCTCGACGCGTGCGGTGCACGAGACGCCGATACGGTGCGGTCGCTCGTCGAGCGAGCCGC
CGCGGCCGGCGTGACCGCGGTGGTCACCGTCGCCGACGACCTGGAGTCCGCGCGCTGGGTCACCCGCGCGGCCGAATGGG
ATCGGCGAGTCTATGCCGCGGTGGCGTTGCACCCGACCCGCGCCGATGCGCTCACCGACGCTGCCCGTGCCGAGCTCGAG
CGATTGGTTGCCCACCCCAGGGTGGTGGCCGTCGGTGAGACCGGAATCGACATGTACTGGCCGGGTCGCCTGGACGGGTG
TGCGGAGCCGCACGTCCAGCGGGAGGCCTTTGCCTGGCATATCGATCTGGCCAAGCGGACCGGTAAACCGCTGATGATCC
ACAATCGTCAGGCCGACCGCGACGTGCTGGACGTGCTGCGGGCCGAGGGCGCGCCGGACACCGTGATCTTGCACTGCTTC
TCGTCGGACGCGGCGATGGCCCGCACGTGTGTGGACGCCGGGTGGCTGCTCAGCCTGTCCGGGACGGTGAGCTTCCGTAC
CGCCCGTGAACTACGGGAAGCCGTCCCGCTGATGCCGGTGGAGCAGCTTTTGGTGGAAACCGATGCACCGTATTTGACCC
CGCATCCCCACCGGGGCTTGGCGAACGAACCGTACTGCCTGCCCTATACCGTGCGGGCGCTGGCTGAACTGGTCAATCGG
CGCCCCGAAGAGGTGGCGCTCATCACCACAAGCAACGCTCGCCGAGCTTATGGGCTAGGGTGGATGCGCCAATGA

Upstream 100 bases:

>100_bases
GTAATAGGGCTTCATTTCGACACCACCCTATTGTGTGCGGGTGAGCTCCGACCGCCCAGCCAGACGAGATCCACCGCCCG
CTCCGGAACCCCTGGCGCCG

Downstream 100 bases:

>100_bases
GCGCGCCGAGCGGCCCATAACACCCGCGCGCCGGAGTTGCTCAACATTGGCCGGTTCGTTACCGTCTTGTGATCGAACGG
GTGGGGCCTCTAGGTTTCGG

Product: putative deoxyribonuclease TatD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MVDAHTHLDACGARDADTVRSLVERAAAAGVTAVVTVADDLESARWVTRAAEWDRRVYAAVALHPTRADALTDAARAELE
RLVAHPRVVAVGETGIDMYWPGRLDGCAEPHVQREAFAWHIDLAKRTGKPLMIHNRQADRDVLDVLRAEGAPDTVILHCF
SSDAAMARTCVDAGWLLSLSGTVSFRTARELREAVPLMPVEQLLVETDAPYLTPHPHRGLANEPYCLPYTVRALAELVNR
RPEEVALITTSNARRAYGLGWMRQ

Sequences:

>Translated_264_residues
MVDAHTHLDACGARDADTVRSLVERAAAAGVTAVVTVADDLESARWVTRAAEWDRRVYAAVALHPTRADALTDAARAELE
RLVAHPRVVAVGETGIDMYWPGRLDGCAEPHVQREAFAWHIDLAKRTGKPLMIHNRQADRDVLDVLRAEGAPDTVILHCF
SSDAAMARTCVDAGWLLSLSGTVSFRTARELREAVPLMPVEQLLVETDAPYLTPHPHRGLANEPYCLPYTVRALAELVNR
RPEEVALITTSNARRAYGLGWMRQ
>Mature_264_residues
MVDAHTHLDACGARDADTVRSLVERAAAAGVTAVVTVADDLESARWVTRAAEWDRRVYAAVALHPTRADALTDAARAELE
RLVAHPRVVAVGETGIDMYWPGRLDGCAEPHVQREAFAWHIDLAKRTGKPLMIHNRQADRDVLDVLRAEGAPDTVILHCF
SSDAAMARTCVDAGWLLSLSGTVSFRTARELREAVPLMPVEQLLVETDAPYLTPHPHRGLANEPYCLPYTVRALAELVNR
RPEEVALITTSNARRAYGLGWMRQ

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI110349730, Length=267, Percent_Identity=28.4644194756554, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI110349734, Length=267, Percent_Identity=28.4644194756554, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI226061853, Length=273, Percent_Identity=28.2051282051282, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI225903424, Length=217, Percent_Identity=31.3364055299539, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI226061614, Length=259, Percent_Identity=26.2548262548263, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI226061595, Length=236, Percent_Identity=28.3898305084746, Blast_Score=78, Evalue=6e-15,
Organism=Homo sapiens, GI14042943, Length=209, Percent_Identity=25.8373205741627, Blast_Score=76, Evalue=4e-14,
Organism=Escherichia coli, GI1787342, Length=269, Percent_Identity=35.6877323420074, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI87082439, Length=258, Percent_Identity=29.8449612403101, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI48994985, Length=257, Percent_Identity=29.5719844357977, Blast_Score=99, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI71980746, Length=266, Percent_Identity=28.1954887218045, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17559024, Length=270, Percent_Identity=29.2592592592593, Blast_Score=109, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17543026, Length=190, Percent_Identity=31.0526315789474, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17565396, Length=234, Percent_Identity=27.7777777777778, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24648690, Length=280, Percent_Identity=30.7142857142857, Blast_Score=105, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24586117, Length=205, Percent_Identity=28.780487804878, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI221330018, Length=205, Percent_Identity=28.780487804878, Blast_Score=71, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 29083; Mature: 29083

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS01137 TATD_1 ; PS01091 TATD_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVDAHTHLDACGARDADTVRSLVERAAAAGVTAVVTVADDLESARWVTRAAEWDRRVYAA
CCCCCCCHHHCCCCCHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHHEEEE
VALHPTRADALTDAARAELERLVAHPRVVAVGETGIDMYWPGRLDGCAEPHVQREAFAWH
EEECCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCEECCCCCCCCCCCCCCHHHHEEE
IDLAKRTGKPLMIHNRQADRDVLDVLRAEGAPDTVILHCFSSDAAMARTCVDAGWLLSLS
EEHHHHCCCEEEEECCCCHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHCCCEEEEEC
GTVSFRTARELREAVPLMPVEQLLVETDAPYLTPHPHRGLANEPYCLPYTVRALAELVNR
CCEEHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCEECHHHHHHHHHHHHC
RPEEVALITTSNARRAYGLGWMRQ
CCCEEEEEEECCCCHHHCCCCCCC
>Mature Secondary Structure
MVDAHTHLDACGARDADTVRSLVERAAAAGVTAVVTVADDLESARWVTRAAEWDRRVYAA
CCCCCCCHHHCCCCCHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHHEEEE
VALHPTRADALTDAARAELERLVAHPRVVAVGETGIDMYWPGRLDGCAEPHVQREAFAWH
EEECCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCEECCCCCCCCCCCCCCHHHHEEE
IDLAKRTGKPLMIHNRQADRDVLDVLRAEGAPDTVILHCFSSDAAMARTCVDAGWLLSLS
EEHHHHCCCEEEEECCCCHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHCCCEEEEEC
GTVSFRTARELREAVPLMPVEQLLVETDAPYLTPHPHRGLANEPYCLPYTVRALAELVNR
CCEEHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCEECHHHHHHHHHHHHC
RPEEVALITTSNARRAYGLGWMRQ
CCCEEEEEEECCCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]