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The map label for this gene is 148660669

Identifier: 148660669

GI number: 148660669

Start: 993905

End: 994762

Strand: Reverse

Name: 148660669

Synonym: MRA_0899

Alternate gene names: NA

Gene position: 994762-993905 (Counterclockwise)

Preceding gene: 148660671

Following gene: 148660668

Centisome position: 22.51

GC content: 60.02

Gene sequence:

>858_bases
GTGCTCTTCAACGCAGTTCATAACAGCCTTCCTCCCAACATCGACATCGACCATGCGATCCTGCGGGGCGAAGATCATCC
GCCAACATGCGCAAAGTGCGTCGCCAGGGTTCGTATATCTGCGCTAGGATCGCTGGATCTCCGGTACCATTCGCTCCGCT
GCTATGCGGCTCCACCAGATGTTGGCCGATGTGAGTTCGTTCCCCCACGCAGACGCGTCCTTATAGCCAACCAGGGATTA
GACGTGAGCAGATTGCCGCCGACGGGCACGGTGACATTGCTCTTAGCCGACGTCGAGGAATCGACCCACCTATGGCAAAT
GTGCCCAGAGGACATGGCGACCGCCATCGCGCACTTGGATCACACTGTGTCGGAAGCTATCACGAATCACGGTGGGGTGC
AGCCGGTCAAACGGTACGAGGGTGATAGCTTCGTTGCGGCTTTCACTCGCGCTAGCGATGCCGCTGCATGCGCGCTGGAT
CTGCAGCGGACCTCGCTCGCGCCGATCCGACTACGTATAGGTCTTCATACAGGCGAGGTACAGTTGCGCGACGAACTCTA
TGTCGGCCCCACTATCAACCGGACGGCGCGTCTCCGCGATTTGGCACACGGGGGTCAGGTTGTCCTGTCAGCTGCGACAG
GTGATTTAGTGACTGGCCGGCTCCCAGCCGATGCATGGCTTGTCGATCTCGGCCGCCACCCGCTGCGCGGTCTACCTCGT
CCCGAATGGGTCATGCAGTTGTGCCACCCCGACATTCGCGAAAAGTTTCCCCCACTGCGCACGGCCAAATCCAGCCCGAC
ATCGATTCTCCCGGCGCAGTTCACCACATTTGTGGGCCGCCGTGCGCAAATAAGCTGA

Upstream 100 bases:

>100_bases
GGATGGGCCAGGTGTCTTCCCCGAACTGTAGTGTGCTTATTGGCTTCGCGGCGCCGCGAAGGTGTTGCGATGACGTGATA
GCAGTGGTCAGACACGTATC

Downstream 100 bases:

>100_bases
GGTGCGGGCACTGTTGGCGCAGAACCGGCTCGTGACGCTATGCGGAACCGGCGGTGTCGGCAAGACCCGTCTGGCAATCC
AGATCGCGAGTGCATCCGAA

Product: putative transcriptional regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 285; Mature: 285

Protein sequence:

>285_residues
MLFNAVHNSLPPNIDIDHAILRGEDHPPTCAKCVARVRISALGSLDLRYHSLRCYAAPPDVGRCEFVPPRRRVLIANQGL
DVSRLPPTGTVTLLLADVEESTHLWQMCPEDMATAIAHLDHTVSEAITNHGGVQPVKRYEGDSFVAAFTRASDAAACALD
LQRTSLAPIRLRIGLHTGEVQLRDELYVGPTINRTARLRDLAHGGQVVLSAATGDLVTGRLPADAWLVDLGRHPLRGLPR
PEWVMQLCHPDIREKFPPLRTAKSSPTSILPAQFTTFVGRRAQIS

Sequences:

>Translated_285_residues
MLFNAVHNSLPPNIDIDHAILRGEDHPPTCAKCVARVRISALGSLDLRYHSLRCYAAPPDVGRCEFVPPRRRVLIANQGL
DVSRLPPTGTVTLLLADVEESTHLWQMCPEDMATAIAHLDHTVSEAITNHGGVQPVKRYEGDSFVAAFTRASDAAACALD
LQRTSLAPIRLRIGLHTGEVQLRDELYVGPTINRTARLRDLAHGGQVVLSAATGDLVTGRLPADAWLVDLGRHPLRGLPR
PEWVMQLCHPDIREKFPPLRTAKSSPTSILPAQFTTFVGRRAQIS
>Mature_285_residues
MLFNAVHNSLPPNIDIDHAILRGEDHPPTCAKCVARVRISALGSLDLRYHSLRCYAAPPDVGRCEFVPPRRRVLIANQGL
DVSRLPPTGTVTLLLADVEESTHLWQMCPEDMATAIAHLDHTVSEAITNHGGVQPVKRYEGDSFVAAFTRASDAAACALD
LQRTSLAPIRLRIGLHTGEVQLRDELYVGPTINRTARLRDLAHGGQVVLSAATGDLVTGRLPADAWLVDLGRHPLRGLPR
PEWVMQLCHPDIREKFPPLRTAKSSPTSILPAQFTTFVGRRAQIS

Specific function: Unknown

COG id: COG2114

COG function: function code T; Adenylate cyclase, family 3 (some proteins contain HAMP domain)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 guanylate cyclase domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y891_MYCTU (Q10551)

Other databases:

- EMBL:   BX842574
- EMBL:   AE000516
- PIR:   H70781
- RefSeq:   NP_215406.1
- RefSeq:   NP_335346.1
- ProteinModelPortal:   Q10551
- SMR:   Q10551
- EnsemblBacteria:   EBMYCT00000001589
- EnsemblBacteria:   EBMYCT00000071716
- GeneID:   885493
- GeneID:   926228
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT0915
- KEGG:   mtu:Rv0891c
- TIGR:   MT0915
- TubercuList:   Rv0891c
- GeneTree:   EBGT00050000014809
- HOGENOM:   HBG565453
- ProtClustDB:   CLSK790812
- GO:   GO:0005829
- InterPro:   IPR001054
- Gene3D:   G3DSA:3.30.70.1230
- SMART:   SM00044

Pfam domain/function: PF00211 Guanylate_cyc; SSF55073 A/G_cyclase

EC number: NA

Molecular weight: Translated: 31232; Mature: 31232

Theoretical pI: Translated: 8.10; Mature: 8.10

Prosite motif: PS50125 GUANYLATE_CYCLASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFNAVHNSLPPNIDIDHAILRGEDHPPTCAKCVARVRISALGSLDLRYHSLRCYAAPPD
CCCCHHHHCCCCCCCCCHHEECCCCCCCHHHHHHHHHHHHHHCCCEEEEEEEEEEECCCC
VGRCEFVPPRRRVLIANQGLDVSRLPPTGTVTLLLADVEESTHLWQMCPEDMATAIAHLD
CCCCCCCCCCCEEEEEECCCCCCCCCCCCEEEEEEEECCCCHHHHHHCHHHHHHHHHHHH
HTVSEAITNHGGVQPVKRYEGDSFVAAFTRASDAAACALDLQRTSLAPIRLRIGLHTGEV
HHHHHHHHCCCCCCHHHHCCCCCEEEEECCCCCCHHEEEEHHHCCCCEEEEEEEEEECCE
QLRDELYVGPTINRTARLRDLAHGGQVVLSAATGDLVTGRLPADAWLVDLGRHPLRGLPR
EEECEEEECCCCCHHHHHHHHCCCCEEEEEECCCCEEECCCCCHHHHHHCCCCCCCCCCC
PEWVMQLCHPDIREKFPPLRTAKSSPTSILPAQFTTFVGRRAQIS
HHHHHHHCCHHHHHHCCCCCCCCCCCCEECHHHHHHHHCCCCCCC
>Mature Secondary Structure
MLFNAVHNSLPPNIDIDHAILRGEDHPPTCAKCVARVRISALGSLDLRYHSLRCYAAPPD
CCCCHHHHCCCCCCCCCHHEECCCCCCCHHHHHHHHHHHHHHCCCEEEEEEEEEEECCCC
VGRCEFVPPRRRVLIANQGLDVSRLPPTGTVTLLLADVEESTHLWQMCPEDMATAIAHLD
CCCCCCCCCCCEEEEEECCCCCCCCCCCCEEEEEEEECCCCHHHHHHCHHHHHHHHHHHH
HTVSEAITNHGGVQPVKRYEGDSFVAAFTRASDAAACALDLQRTSLAPIRLRIGLHTGEV
HHHHHHHHCCCCCCHHHHCCCCCEEEEECCCCCCHHEEEEHHHCCCCEEEEEEEEEECCE
QLRDELYVGPTINRTARLRDLAHGGQVVLSAATGDLVTGRLPADAWLVDLGRHPLRGLPR
EEECEEEECCCCCHHHHHHHHCCCCEEEEEECCCCEEECCCCCHHHHHHCCCCCCCCCCC
PEWVMQLCHPDIREKFPPLRTAKSSPTSILPAQFTTFVGRRAQIS
HHHHHHHCCHHHHHHCCCCCCCCCCCCEECHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036