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The map label for this gene is 148660653

Identifier: 148660653

GI number: 148660653

Start: 975597

End: 977243

Strand: Reverse

Name: 148660653

Synonym: MRA_0883

Alternate gene names: NA

Gene position: 977243-975597 (Counterclockwise)

Preceding gene: 148660655

Following gene: 148660652

Centisome position: 22.11

GC content: 65.88

Gene sequence:

>1647_bases
ATGGCCCCAACCCCGGGCCGCCGGACCCGAAACGGATCGGTCAACGGGCACCCTGGCATGGCCAACTACCCTCCCGACGA
CGCCAACTATCGCCGATCGCGTCGACCTCCGCCGATGCCCAGTGCCAACCGCTATCTCCCGCCGCTGGGCGAGCAGCCCG
AACCTGAACGCAGCCGCGTACCGCCACGGACTACAAGGGCGGGCGAGCGGATCACCGTCACCCGCGCCGCGGCCATGCGC
AGCCGCGAAATGGGTTCTCGGATGTACTTGCTGGTGCACCGGGCCGCTACCGCAGACGGCGCCGACAAGTCTGGACTGAC
GGCATTGACCTGGCCGGTAATGGCGAACTTCGCGGTCGACTCGGCAATGGCGGTAGCACTGGCAAACACACTATTCTTTG
CGGCCGCCAGCGGGGAGAGCAAGTCCAGGGTCGCCTTGTACCTGTTGATCACCATCGCGCCGTTCGCCGTGATCGCTCCA
CTCATCGGTCCGGCACTCGACCGGCTGCAGCATGGCCGTCGCGTCGCCTTGGCGCTGTCATTCGGACTTCGGACCGCGTT
GGCGGTGGTGCTGATCATGAACTACGACGGCGCCACCGGCAGCTTCCCGTCATGGGTGCTCTATCCCTGTGCGCTGGCCA
TGATGGTGTTCTCGAAGTCGTTCAGCGTGCTGCGCAGCGCAGTGACACCGAGGGTGATGCCGCCAACCATCGACTTGGTC
CGGGTCAACTCACGGCTGACCGTGTTCGGCCTGCTCGGCGGCACCATCGCTGGTGGCGCGATTGCGGCCGGAGTCGAATT
CGTCTGCACCCACCTGTTCCAGCTGCCGGGCGCGTTGTTCGTCGTCGTCGCGATCACCATCGCTGGCGCTTCGCTGTCGA
TGCGCATTCCGCGCTGGGTCGAGGTGACCAGCGGTGAGGTCCCGGCCACATTGAGCTACCACCGGGATAGGGGCAGACTA
CGGCGACGCTGGCCGGAGGAAGTCAAGAACCTCGGCGGAACACTCCGACAACCGTTGGGCCGCAACATCATTACCTCCCT
GTGGGGTAACTGCACCATCAAGGTGATGGTCGGCTTTCTGTTCTTGTATCCGGCGTTTGTCGCCAAGGCGCACGAAGCCA
ACGGGTGGGTGCAATTGGGCATGCTGGGCCTGATCGGCGCGGCGGCCGCGGTCGGCAACTTCGCCGGCAATTTCACCAGC
GCACGCCTGCAGCTAGGCAGGCCAGCTGTGCTGGTGGTGCGCTGCACCGTGCTAGTTACCGTGTTAGCCATCGCGGCCGC
GGTGGCCGGCAGCCTGGCAGCGACAGCGATTGCCACCCTGATCACGGCAGGGTCCAGTGCCATTGCTAAAGCCTCGCTGG
ACGCCTCGTTGCAGCACGACCTGCCCGAGGAGTCGCGGGCATCGGGGTTTGGGCGTTCCGAGTCGACTCTTCAGCTGGCC
TGGGTGCTGGGCGGCGCGGTGGGCGTGTTGGTGTACACCGAGCTGTGGGTGGGCTTCACTGCGGTGAGCGCGCTGCTGAT
CCTGGGTCTGGCTCAGACCATCGTCAGCTTCCGCGGCGATTCGCTGATCCCTGGCCTGGGCGGTAATCGGCCCGTGATGG
CCGAGCAAGAAACCACCCGTCGTGGTGCGGCGGTGGCGCCGCAGTGA

Upstream 100 bases:

>100_bases
GAAGACACGGCCGGCAAGCCACACCCGGTTGGCTACGCCAGGAGTCCGGATAGGACAGAATTGATTTGTGTCCGGACGGC
GAGGTGATCATCCGGGCCGG

Downstream 100 bases:

>100_bases
AGCGCGGTGTCGCAACGCTGCCGGTGATCCTGGTGATTCTGCTCTCGGTGGCGGCCGGGGCCGGTGCATGGCTGCTAGTA
CGCGGACACGGTCCGCAGCA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 548; Mature: 547

Protein sequence:

>548_residues
MAPTPGRRTRNGSVNGHPGMANYPPDDANYRRSRRPPPMPSANRYLPPLGEQPEPERSRVPPRTTRAGERITVTRAAAMR
SREMGSRMYLLVHRAATADGADKSGLTALTWPVMANFAVDSAMAVALANTLFFAAASGESKSRVALYLLITIAPFAVIAP
LIGPALDRLQHGRRVALALSFGLRTALAVVLIMNYDGATGSFPSWVLYPCALAMMVFSKSFSVLRSAVTPRVMPPTIDLV
RVNSRLTVFGLLGGTIAGGAIAAGVEFVCTHLFQLPGALFVVVAITIAGASLSMRIPRWVEVTSGEVPATLSYHRDRGRL
RRRWPEEVKNLGGTLRQPLGRNIITSLWGNCTIKVMVGFLFLYPAFVAKAHEANGWVQLGMLGLIGAAAAVGNFAGNFTS
ARLQLGRPAVLVVRCTVLVTVLAIAAAVAGSLAATAIATLITAGSSAIAKASLDASLQHDLPEESRASGFGRSESTLQLA
WVLGGAVGVLVYTELWVGFTAVSALLILGLAQTIVSFRGDSLIPGLGGNRPVMAEQETTRRGAAVAPQ

Sequences:

>Translated_548_residues
MAPTPGRRTRNGSVNGHPGMANYPPDDANYRRSRRPPPMPSANRYLPPLGEQPEPERSRVPPRTTRAGERITVTRAAAMR
SREMGSRMYLLVHRAATADGADKSGLTALTWPVMANFAVDSAMAVALANTLFFAAASGESKSRVALYLLITIAPFAVIAP
LIGPALDRLQHGRRVALALSFGLRTALAVVLIMNYDGATGSFPSWVLYPCALAMMVFSKSFSVLRSAVTPRVMPPTIDLV
RVNSRLTVFGLLGGTIAGGAIAAGVEFVCTHLFQLPGALFVVVAITIAGASLSMRIPRWVEVTSGEVPATLSYHRDRGRL
RRRWPEEVKNLGGTLRQPLGRNIITSLWGNCTIKVMVGFLFLYPAFVAKAHEANGWVQLGMLGLIGAAAAVGNFAGNFTS
ARLQLGRPAVLVVRCTVLVTVLAIAAAVAGSLAATAIATLITAGSSAIAKASLDASLQHDLPEESRASGFGRSESTLQLA
WVLGGAVGVLVYTELWVGFTAVSALLILGLAQTIVSFRGDSLIPGLGGNRPVMAEQETTRRGAAVAPQ
>Mature_547_residues
APTPGRRTRNGSVNGHPGMANYPPDDANYRRSRRPPPMPSANRYLPPLGEQPEPERSRVPPRTTRAGERITVTRAAAMRS
REMGSRMYLLVHRAATADGADKSGLTALTWPVMANFAVDSAMAVALANTLFFAAASGESKSRVALYLLITIAPFAVIAPL
IGPALDRLQHGRRVALALSFGLRTALAVVLIMNYDGATGSFPSWVLYPCALAMMVFSKSFSVLRSAVTPRVMPPTIDLVR
VNSRLTVFGLLGGTIAGGAIAAGVEFVCTHLFQLPGALFVVVAITIAGASLSMRIPRWVEVTSGEVPATLSYHRDRGRLR
RRWPEEVKNLGGTLRQPLGRNIITSLWGNCTIKVMVGFLFLYPAFVAKAHEANGWVQLGMLGLIGAAAAVGNFAGNFTSA
RLQLGRPAVLVVRCTVLVTVLAIAAAVAGSLAATAIATLITAGSSAIAKASLDASLQHDLPEESRASGFGRSESTLQLAW
VLGGAVGVLVYTELWVGFTAVSALLILGLAQTIVSFRGDSLIPGLGGNRPVMAEQETTRRGAAVAPQ

Specific function: Unknown

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To M.leprae ML2143

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y876_MYCTU (Q10564)

Other databases:

- EMBL:   BX842574
- EMBL:   AE000516
- PIR:   A70780
- RefSeq:   NP_215391.1
- RefSeq:   NP_335327.1
- ProteinModelPortal:   Q10564
- EnsemblBacteria:   EBMYCT00000002581
- EnsemblBacteria:   EBMYCT00000069910
- GeneID:   885562
- GeneID:   926209
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT0899
- KEGG:   mtu:Rv0876c
- TIGR:   MT0899
- TubercuList:   Rv0876c
- GeneTree:   EBGT00050000014799
- HOGENOM:   HBG565082
- OMA:   VLQLSWV
- ProtClustDB:   CLSK871868
- InterPro:   IPR011701
- InterPro:   IPR016196

Pfam domain/function: PF07690 MFS_1; SSF103473 MFS_gen_substrate_transporter

EC number: NA

Molecular weight: Translated: 57938; Mature: 57807

Theoretical pI: Translated: 11.35; Mature: 11.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1c44d244)-; HASH(0x1d4fdfb4)-; HASH(0x1d29f100)-; HASH(0x1b1b2800)-; HASH(0x1d4c80e4)-; HASH(0x1cb36d70)-; HASH(0x1c58735c)-; HASH(0x1d2a526c)-; HASH(0x1d264cac)-; HASH(0x1c40ce88)-; HASH(0x1d489150)-;

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPTPGRRTRNGSVNGHPGMANYPPDDANYRRSRRPPPMPSANRYLPPLGEQPEPERSRV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCC
PPRTTRAGERITVTRAAAMRSREMGSRMYLLVHRAATADGADKSGLTALTWPVMANFAVD
CCCCCCCCCEEEEHHHHHHHHHHCCCEEEEEEEEHHCCCCCCCCCCEEEEHHHHHHHHHH
SAMAVALANTLFFAAASGESKSRVALYLLITIAPFAVIAPLIGPALDRLQHGRRVALALS
HHHHHHHHHHHHEEECCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEH
FGLRTALAVVLIMNYDGATGSFPSWVLYPCALAMMVFSKSFSVLRSAVTPRVMPPTIDLV
HHHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEE
RVNSRLTVFGLLGGTIAGGAIAAGVEFVCTHLFQLPGALFVVVAITIAGASLSMRIPRWV
EECCCEEEEEECCCHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEECCCCEE
EVTSGEVPATLSYHRDRGRLRRRWPEEVKNLGGTLRQPLGRNIITSLWGNCTIKVMVGFL
EECCCCCCEEHHHHHHHHHHHHCCHHHHHHCCHHHHHHHCHHHHHHHHCCHHHHHHHHHH
FLYPAFVAKAHEANGWVQLGMLGLIGAAAAVGNFAGNFTSARLQLGRPAVLVVRCTVLVT
HHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCEEHHHHHHHHHH
VLAIAAAVAGSLAATAIATLITAGSSAIAKASLDASLQHDLPEESRASGFGRSESTLQLA
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHCCCCHHHHCCCCCCCCCEEEH
WVLGGAVGVLVYTELWVGFTAVSALLILGLAQTIVSFRGDSLIPGLGGNRPVMAEQETTR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHC
RGAAVAPQ
CCCCCCCH
>Mature Secondary Structure 
APTPGRRTRNGSVNGHPGMANYPPDDANYRRSRRPPPMPSANRYLPPLGEQPEPERSRV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCC
PPRTTRAGERITVTRAAAMRSREMGSRMYLLVHRAATADGADKSGLTALTWPVMANFAVD
CCCCCCCCCEEEEHHHHHHHHHHCCCEEEEEEEEHHCCCCCCCCCCEEEEHHHHHHHHHH
SAMAVALANTLFFAAASGESKSRVALYLLITIAPFAVIAPLIGPALDRLQHGRRVALALS
HHHHHHHHHHHHEEECCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEH
FGLRTALAVVLIMNYDGATGSFPSWVLYPCALAMMVFSKSFSVLRSAVTPRVMPPTIDLV
HHHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEE
RVNSRLTVFGLLGGTIAGGAIAAGVEFVCTHLFQLPGALFVVVAITIAGASLSMRIPRWV
EECCCEEEEEECCCHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEECCCCEE
EVTSGEVPATLSYHRDRGRLRRRWPEEVKNLGGTLRQPLGRNIITSLWGNCTIKVMVGFL
EECCCCCCEEHHHHHHHHHHHHCCHHHHHHCCHHHHHHHCHHHHHHHHCCHHHHHHHHHH
FLYPAFVAKAHEANGWVQLGMLGLIGAAAAVGNFAGNFTSARLQLGRPAVLVVRCTVLVT
HHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCEEHHHHHHHHHH
VLAIAAAVAGSLAATAIATLITAGSSAIAKASLDASLQHDLPEESRASGFGRSESTLQLA
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHCCCCHHHHCCCCCCCCCEEEH
WVLGGAVGVLVYTELWVGFTAVSALLILGLAQTIVSFRGDSLIPGLGGNRPVMAEQETTR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHC
RGAAVAPQ
CCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036