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The map label for this gene is ptrBb [H]

Identifier: 148660559

GI number: 148660559

Start: 876038

End: 877696

Strand: Direct

Name: ptrBb [H]

Synonym: MRA_0791

Alternate gene names: 148660559

Gene position: 876038-877696 (Clockwise)

Preceding gene: 148660558

Following gene: 148660561

Centisome position: 19.82

GC content: 62.75

Gene sequence:

>1659_bases
GTGACGAACGATATACCTTGCGGTTCAAGGATTTACGCACCGGAGAACAGTACCCGGACGAGATCGCCGGGATCGGAGCG
GGAGTCACCTGGGCAGCTGACAACCACTGTCTACTACACCACCGTGGACGCGGCCTGGCGTCCGGACACAGTGTGGCGAT
ACCGACTAGGGTCCGGCGAATCGTCGGAGCGGGTTTACCACGAAGCCGATGATCGGTTCTGGCTCGCGGTGGGGCGTACT
CGCAGCAACGCCTATCTGCTGATTGCGGCGGGGTCGTCCATCACTTCGGAGGTCCGTTACGCGCACGCGGCAGATCCGAC
AGCGCAGTTCAGCGTGGTGCTGCCGCGCCGCGACGGCGTCGAGTACTCGGTGGAGCATGCGGTCATAGCTGGCCAGGACC
GGTTTCTGATCCTGCACAACGACGGCGCGGTGAACTTCACACTGGTAGAGGCCCCGGTCGAGGATCCTGCGCGGCAACGC
ACCCTCATCGCCCACCGCGACGACGTCCGACTCGACGCGGTGGATGCCTTGGCCGGCCATCTGGTAGTCAGCTATCGGCG
CGAGGCGCTGCCGCGGGTTCAACTGTGGCCGATCGGGCCTGACGGAAACTATGGTGAGCCCGAAGAGATCTCGTTCGACT
CCGAGCTGATGTCGGCCGGACTGGGGCCCAACCCCAACTGGGATTCGCCCAAACTGCGGGTCGGTGCCGGATCTTTCGTC
ACCCCGGTGCGGATCTACGACATCGACCTGGTCACTGGCGAGCGTACCTTGCTGAAAGAACAGCCCGTACTGGGCGGCTA
CCGCCGCGAAGACTATGTGGAGCGGCGTGACTGGGCGTACGGAGACGACGGCACCCGGATCCCGGTCTCGATAGTGCACC
GAGCCGATATCGAATTCCCGGCACCTGCGTTGATCTATGGCTACGGCGCCTACGAGATCTGTGAGGATCCGCGGTTTTCC
ATCGCTCGGTTGTCGCTGCTGGATCGCGGGATGGTGTTCGTCGTCGCCCACGTTCGCGGCGGCGGTGAGATGGGCAGGCT
GTGGTATGAAAACGGCAAGCTACTGGACAAGAAGAACACGTTCACCGACTTCATCGCGGTGGCAAGACATCTGGTGGACA
CGGGACTTACTTCCCAGCAGCAGCTGGTGGCATTGGGGGGTAGCGCGGGCGGTCTGCTGATGGGCGCGGTGGCCAACATG
GCACCGGATCTCTTCGCCGGAATCCTTGCGCAGGTGCCGTTCGTGGACCCGCTGACCACCATCTTGGATCCATCGTTGCC
GCTGACCGTCACCGAGTGGGACGAATGGGGAAATCCGTTGAACGACAGCGATGTCTATGCCTATGTGAAATCGTATTCGC
CGTACGAGAACGTCACGGCCCAAAAGTACCCGGCCATCCTGGCAATGACGTCGCTGAACGACACCAGGGTCTATTACGTG
GAGCCGGCCAAGTGGGTGGCCGCGTTGCGGCACGCCAAGACCGACGGCAATTCCGTGCTGTTGAAGACCCAGATGCACGC
CGGTCATGGTGGGATCAGTGGCCGCTACGAGCGCTGGAAGGAGACCGCGTTTCAATACGGGTGGTTGCTAGCTACTGCCG
ACAGCGACCGTTACGGCGGCGGCCAGGGAAACGACCTCGATGGCGCTGCGCCAGCATAG

Upstream 100 bases:

>100_bases
GACGAGAACGTGGAAGCTGACGGCCACGACTTCTTCGCACTGGGCGCGGCCAGCGTCAGCCTGGACGATAACCTCTTAGC
GTATTCCGTTGATGTCGTAG

Downstream 100 bases:

>100_bases
CCGGTGGGATCGGCCATTCGGGATGCGTAGACATTGGCTCCGAACATGGCCAGCATCAGCGCCAGCGAGCATACCGCCGC
TGCCATGCGGGTGTCGGGCA

Product: putative protease II PtrBb

Products: NA

Alternate protein names: Oligopeptidase B; Protease II [H]

Number of amino acids: Translated: 552; Mature: 551

Protein sequence:

>552_residues
MTNDIPCGSRIYAPENSTRTRSPGSERESPGQLTTTVYYTTVDAAWRPDTVWRYRLGSGESSERVYHEADDRFWLAVGRT
RSNAYLLIAAGSSITSEVRYAHAADPTAQFSVVLPRRDGVEYSVEHAVIAGQDRFLILHNDGAVNFTLVEAPVEDPARQR
TLIAHRDDVRLDAVDALAGHLVVSYRREALPRVQLWPIGPDGNYGEPEEISFDSELMSAGLGPNPNWDSPKLRVGAGSFV
TPVRIYDIDLVTGERTLLKEQPVLGGYRREDYVERRDWAYGDDGTRIPVSIVHRADIEFPAPALIYGYGAYEICEDPRFS
IARLSLLDRGMVFVVAHVRGGGEMGRLWYENGKLLDKKNTFTDFIAVARHLVDTGLTSQQQLVALGGSAGGLLMGAVANM
APDLFAGILAQVPFVDPLTTILDPSLPLTVTEWDEWGNPLNDSDVYAYVKSYSPYENVTAQKYPAILAMTSLNDTRVYYV
EPAKWVAALRHAKTDGNSVLLKTQMHAGHGGISGRYERWKETAFQYGWLLATADSDRYGGGQGNDLDGAAPA

Sequences:

>Translated_552_residues
MTNDIPCGSRIYAPENSTRTRSPGSERESPGQLTTTVYYTTVDAAWRPDTVWRYRLGSGESSERVYHEADDRFWLAVGRT
RSNAYLLIAAGSSITSEVRYAHAADPTAQFSVVLPRRDGVEYSVEHAVIAGQDRFLILHNDGAVNFTLVEAPVEDPARQR
TLIAHRDDVRLDAVDALAGHLVVSYRREALPRVQLWPIGPDGNYGEPEEISFDSELMSAGLGPNPNWDSPKLRVGAGSFV
TPVRIYDIDLVTGERTLLKEQPVLGGYRREDYVERRDWAYGDDGTRIPVSIVHRADIEFPAPALIYGYGAYEICEDPRFS
IARLSLLDRGMVFVVAHVRGGGEMGRLWYENGKLLDKKNTFTDFIAVARHLVDTGLTSQQQLVALGGSAGGLLMGAVANM
APDLFAGILAQVPFVDPLTTILDPSLPLTVTEWDEWGNPLNDSDVYAYVKSYSPYENVTAQKYPAILAMTSLNDTRVYYV
EPAKWVAALRHAKTDGNSVLLKTQMHAGHGGISGRYERWKETAFQYGWLLATADSDRYGGGQGNDLDGAAPA
>Mature_551_residues
TNDIPCGSRIYAPENSTRTRSPGSERESPGQLTTTVYYTTVDAAWRPDTVWRYRLGSGESSERVYHEADDRFWLAVGRTR
SNAYLLIAAGSSITSEVRYAHAADPTAQFSVVLPRRDGVEYSVEHAVIAGQDRFLILHNDGAVNFTLVEAPVEDPARQRT
LIAHRDDVRLDAVDALAGHLVVSYRREALPRVQLWPIGPDGNYGEPEEISFDSELMSAGLGPNPNWDSPKLRVGAGSFVT
PVRIYDIDLVTGERTLLKEQPVLGGYRREDYVERRDWAYGDDGTRIPVSIVHRADIEFPAPALIYGYGAYEICEDPRFSI
ARLSLLDRGMVFVVAHVRGGGEMGRLWYENGKLLDKKNTFTDFIAVARHLVDTGLTSQQQLVALGGSAGGLLMGAVANMA
PDLFAGILAQVPFVDPLTTILDPSLPLTVTEWDEWGNPLNDSDVYAYVKSYSPYENVTAQKYPAILAMTSLNDTRVYYVE
PAKWVAALRHAKTDGNSVLLKTQMHAGHGGISGRYERWKETAFQYGWLLATADSDRYGGGQGNDLDGAAPA

Specific function: Cleaves peptide bonds on the C-terminal side of lysyl and argininyl residues [H]

COG id: COG1770

COG function: function code E; Protease II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S9A family [H]

Homologues:

Organism=Homo sapiens, GI284172438, Length=489, Percent_Identity=28.6298568507157, Blast_Score=162, Evalue=9e-40,
Organism=Homo sapiens, GI284172431, Length=489, Percent_Identity=28.6298568507157, Blast_Score=162, Evalue=9e-40,
Organism=Homo sapiens, GI284172420, Length=472, Percent_Identity=29.8728813559322, Blast_Score=162, Evalue=9e-40,
Organism=Homo sapiens, GI284172413, Length=472, Percent_Identity=29.8728813559322, Blast_Score=162, Evalue=9e-40,
Organism=Homo sapiens, GI70778815, Length=472, Percent_Identity=29.8728813559322, Blast_Score=162, Evalue=9e-40,
Organism=Homo sapiens, GI41349456, Length=289, Percent_Identity=33.9100346020761, Blast_Score=151, Evalue=1e-36,
Organism=Homo sapiens, GI108860686, Length=303, Percent_Identity=34.6534653465347, Blast_Score=135, Evalue=1e-31,
Organism=Homo sapiens, GI108860692, Length=223, Percent_Identity=39.0134529147982, Blast_Score=132, Evalue=1e-30,
Organism=Escherichia coli, GI1788150, Length=489, Percent_Identity=42.5357873210634, Blast_Score=370, Evalue=1e-103,
Organism=Drosophila melanogaster, GI24583414, Length=447, Percent_Identity=29.9776286353468, Blast_Score=169, Evalue=3e-42,
Organism=Drosophila melanogaster, GI221510989, Length=451, Percent_Identity=29.2682926829268, Blast_Score=150, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002471
- InterPro:   IPR001375
- InterPro:   IPR002470
- InterPro:   IPR004106 [H]

Pfam domain/function: PF00326 Peptidase_S9; PF02897 Peptidase_S9_N [H]

EC number: =3.4.21.83 [H]

Molecular weight: Translated: 60897; Mature: 60766

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNDIPCGSRIYAPENSTRTRSPGSERESPGQLTTTVYYTTVDAAWRPDTVWRYRLGSGE
CCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCEEEEEEEEEECCCCCCCCEEEEEECCCC
SSERVYHEADDRFWLAVGRTRSNAYLLIAAGSSITSEVRYAHAADPTAQFSVVLPRRDGV
CCCCCEECCCCEEEEEEECCCCCEEEEEECCCCHHHHHHEEECCCCCCEEEEEEECCCCC
EYSVEHAVIAGQDRFLILHNDGAVNFTLVEAPVEDPARQRTLIAHRDDVRLDAVDALAGH
CEEEEEEEEECCCCEEEEECCCCEEEEEEECCCCCCHHHCEEEEECCCCEEHHHHHHHHH
LVVSYRREALPRVQLWPIGPDGNYGEPEEISFDSELMSAGLGPNPNWDSPKLRVGAGSFV
HHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCEEEECCCCCC
TPVRIYDIDLVTGERTLLKEQPVLGGYRREDYVERRDWAYGDDGTRIPVSIVHRADIEFP
CEEEEEEEEEECCCHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCC
APALIYGYGAYEICEDPRFSIARLSLLDRGMVFVVAHVRGGGEMGRLWYENGKLLDKKNT
CCEEEEECCCHHHCCCCCCHHHHHHHHCCCEEEEEEEECCCCCCCEEEECCCEEEECCCC
FTDFIAVARHLVDTGLTSQQQLVALGGSAGGLLMGAVANMAPDLFAGILAQVPFVDPLTT
HHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHCCHHHHHHHHHHCCCCCHHHH
ILDPSLPLTVTEWDEWGNPLNDSDVYAYVKSYSPYENVTAQKYPAILAMTSLNDTRVYYV
HHCCCCCEEEECHHHCCCCCCCCCEEEEEECCCCCCCCCHHHCCEEEEEEECCCCEEEEE
EPAKWVAALRHAKTDGNSVLLKTQMHAGHGGISGRYERWKETAFQYGWLLATADSDRYGG
CHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHEEEEEEECCCCCCCC
GQGNDLDGAAPA
CCCCCCCCCCCC
>Mature Secondary Structure 
TNDIPCGSRIYAPENSTRTRSPGSERESPGQLTTTVYYTTVDAAWRPDTVWRYRLGSGE
CCCCCCCCEEECCCCCCCCCCCCCCCCCCCCEEEEEEEEEECCCCCCCCEEEEEECCCC
SSERVYHEADDRFWLAVGRTRSNAYLLIAAGSSITSEVRYAHAADPTAQFSVVLPRRDGV
CCCCCEECCCCEEEEEEECCCCCEEEEEECCCCHHHHHHEEECCCCCCEEEEEEECCCCC
EYSVEHAVIAGQDRFLILHNDGAVNFTLVEAPVEDPARQRTLIAHRDDVRLDAVDALAGH
CEEEEEEEEECCCCEEEEECCCCEEEEEEECCCCCCHHHCEEEEECCCCEEHHHHHHHHH
LVVSYRREALPRVQLWPIGPDGNYGEPEEISFDSELMSAGLGPNPNWDSPKLRVGAGSFV
HHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCEEEECCCCCC
TPVRIYDIDLVTGERTLLKEQPVLGGYRREDYVERRDWAYGDDGTRIPVSIVHRADIEFP
CEEEEEEEEEECCCHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCC
APALIYGYGAYEICEDPRFSIARLSLLDRGMVFVVAHVRGGGEMGRLWYENGKLLDKKNT
CCEEEEECCCHHHCCCCCCHHHHHHHHCCCEEEEEEEECCCCCCCEEEECCCEEEECCCC
FTDFIAVARHLVDTGLTSQQQLVALGGSAGGLLMGAVANMAPDLFAGILAQVPFVDPLTT
HHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHCCHHHHHHHHHHCCCCCHHHH
ILDPSLPLTVTEWDEWGNPLNDSDVYAYVKSYSPYENVTAQKYPAILAMTSLNDTRVYYV
HHCCCCCEEEECHHHCCCCCCCCCEEEEEECCCCCCCCCHHHCCEEEEEEECCCCEEEEE
EPAKWVAALRHAKTDGNSVLLKTQMHAGHGGISGRYERWKETAFQYGWLLATADSDRYGG
CHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHEEEEEEECCCCCCCC
GQGNDLDGAAPA
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7629037 [H]