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The map label for this gene is esxH

Identifier: 148660054

GI number: 148660054

Start: 353210

End: 353500

Strand: Direct

Name: esxH

Synonym: MRA_0297

Alternate gene names: 148660054

Gene position: 353210-353500 (Clockwise)

Preceding gene: 148660053

Following gene: 148660055

Centisome position: 7.99

GC content: 62.54

Gene sequence:

>291_bases
ATGTCGCAAATCATGTACAACTACCCCGCGATGTTGGGTCACGCCGGGGATATGGCCGGATATGCCGGCACGCTGCAGAG
CTTGGGTGCCGAGATCGCCGTGGAGCAGGCCGCGTTGCAGAGTGCGTGGCAGGGCGATACCGGGATCACGTATCAGGCGT
GGCAGGCACAGTGGAACCAGGCCATGGAAGATTTGGTGCGGGCCTATCATGCGATGTCCAGCACCCATGAAGCCAACACC
ATGGCGATGATGGCCCGCGACACGGCCGAAGCCGCCAAATGGGGCGGCTAG

Upstream 100 bases:

>100_bases
ATCTGGGTGAGGCCGCCGGTACCTATGTGGCCGCCGATGCTGCGGCCGCGTCGACCTATACCGGGTTCTGATCGAACCCT
GCTGACCGAGAGGACTTGTG

Downstream 100 bases:

>100_bases
CTCGCGCTACATGGATGCAACACCCAACGCCGTCGAGCTGACGGTCGACAACGCTTGGTTCATCGCTGAAACCATTGGGG
CGGGGACCTTTCCGTGGGTG

Product: antigen Esxh

Products: NA

Alternate protein names: 10 kDa antigen CFP7; CFP-7; Low molecular weight protein antigen 7; Protein TB10.4

Number of amino acids: Translated: 96; Mature: 95

Protein sequence:

>96_residues
MSQIMYNYPAMLGHAGDMAGYAGTLQSLGAEIAVEQAALQSAWQGDTGITYQAWQAQWNQAMEDLVRAYHAMSSTHEANT
MAMMARDTAEAAKWGG

Sequences:

>Translated_96_residues
MSQIMYNYPAMLGHAGDMAGYAGTLQSLGAEIAVEQAALQSAWQGDTGITYQAWQAQWNQAMEDLVRAYHAMSSTHEANT
MAMMARDTAEAAKWGG
>Mature_95_residues
SQIMYNYPAMLGHAGDMAGYAGTLQSLGAEIAVEQAALQSAWQGDTGITYQAWQAQWNQAMEDLVRAYHAMSSTHEANTM
AMMARDTAEAAKWGG

Specific function: Unknown

COG id: COG4842

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ESAT-6 (esx) family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ESXH_MYCBO (P0A569)

Other databases:

- EMBL:   BX248335
- RefSeq:   NP_853960.1
- ProteinModelPortal:   P0A569
- SMR:   P0A569
- EnsemblBacteria:   EBMYCT00000015832
- GeneID:   1091122
- GenomeReviews:   BX248333_GR
- KEGG:   mbo:Mb0296
- GeneTree:   EBGT00050000016281
- HOGENOM:   HBG565735
- OMA:   SGYAGTM
- ProtClustDB:   CLSK790405
- BioCyc:   MBOV233413:MB0296-MONOMER
- InterPro:   IPR010310

Pfam domain/function: PF06013 WXG100

EC number: NA

Molecular weight: Translated: 10391; Mature: 10259

Theoretical pI: Translated: 4.35; Mature: 4.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
9.4 %Met     (Translated Protein)
9.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
8.4 %Met     (Mature Protein)
8.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQIMYNYPAMLGHAGDMAGYAGTLQSLGAEIAVEQAALQSAWQGDTGITYQAWQAQWNQ
CCCCHHCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
AMEDLVRAYHAMSSTHEANTMAMMARDTAEAAKWGG
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SQIMYNYPAMLGHAGDMAGYAGTLQSLGAEIAVEQAALQSAWQGDTGITYQAWQAQWNQ
CCCHHCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
AMEDLVRAYHAMSSTHEANTMAMMARDTAEAAKWGG
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972