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The map label for this gene is rppH

Identifier: 148654125

GI number: 148654125

Start: 2896350

End: 2896871

Strand: Direct

Name: rppH

Synonym: PsycPRwf_2328

Alternate gene names: 148654125

Gene position: 2896350-2896871 (Clockwise)

Preceding gene: 148654121

Following gene: 148654127

Centisome position: 97.23

GC content: 47.7

Gene sequence:

>522_bases
ATGATTGATGCAGACGGCTTTAGAGCCAATGTCGGTATCATCTTGGCAAATACACAAGGACAAGTACTATGGGCAAAACG
AGTTGGTCATGATTCTTGGCAGTTCCCGCAAGGGGGTATCGATGAGGGAGAAACCCCTCTTGATGCTATGTACCGAGAGC
TGTGGGAGGAGGTAGGCTTATATCCTCGACACGTCCAGCTTTTGGCTGCTACTGACAATTGGCTAAGGTATCGCCTGCCC
AAACGTTACATACGTCACGGGCAGCATCCTTTGTGTATAGGGCAAAAACAGAAGTGGTTTTTGCTTAAGCTAGATGAGCC
GAATACCGAACATATCCGCTTTGACACCGCAAAGCCAGAGTTTGACCATTGGGAATGGGTCAGCTACTGGTATCCGCTGG
GTCAAGTGGTTCATTTTAAACGAGGTGTGTATCGCCGTGCGCTGCGAGAGCTGGCACGTGAGTTACCACTTAAAAAGGAA
TTGATTTTACCTGAGACTAAAAACCATTTGCTTCAGGTTTGA

Upstream 100 bases:

>100_bases
GTTGTTTATTGGAAATTAAAACGATAACAGATATTCAAGCGCAGCTTTAAGGCAGTAGACTGATTTTATTTCAACATTTC
TAAATTTTAAGGTTTTCGTC

Downstream 100 bases:

>100_bases
TTTCAATAAAGTTTTGCGTTTAATTTGAGTATGATTTAGTTTTTAACTTATTTTTTATGTGAAGAGGCCTGTATCTAGTG
CTACAGGCCTCTTTTTCGTC

Product: dinucleoside polyphosphate hydrolase

Products: NA

Alternate protein names: (Di)nucleoside polyphosphate hydrolase

Number of amino acids: Translated: 173; Mature: 173

Protein sequence:

>173_residues
MIDADGFRANVGIILANTQGQVLWAKRVGHDSWQFPQGGIDEGETPLDAMYRELWEEVGLYPRHVQLLAATDNWLRYRLP
KRYIRHGQHPLCIGQKQKWFLLKLDEPNTEHIRFDTAKPEFDHWEWVSYWYPLGQVVHFKRGVYRRALRELARELPLKKE
LILPETKNHLLQV

Sequences:

>Translated_173_residues
MIDADGFRANVGIILANTQGQVLWAKRVGHDSWQFPQGGIDEGETPLDAMYRELWEEVGLYPRHVQLLAATDNWLRYRLP
KRYIRHGQHPLCIGQKQKWFLLKLDEPNTEHIRFDTAKPEFDHWEWVSYWYPLGQVVHFKRGVYRRALRELARELPLKKE
LILPETKNHLLQV
>Mature_173_residues
MIDADGFRANVGIILANTQGQVLWAKRVGHDSWQFPQGGIDEGETPLDAMYRELWEEVGLYPRHVQLLAATDNWLRYRLP
KRYIRHGQHPLCIGQKQKWFLLKLDEPNTEHIRFDTAKPEFDHWEWVSYWYPLGQVVHFKRGVYRRALRELARELPLKKE
LILPETKNHLLQV

Specific function: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain

Homologues:

Organism=Escherichia coli, GI1789194, Length=152, Percent_Identity=61.1842105263158, Blast_Score=201, Evalue=2e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RPPH_PSYWF (A5WHX7)

Other databases:

- EMBL:   CP000713
- RefSeq:   YP_001281218.1
- ProteinModelPortal:   A5WHX7
- SMR:   A5WHX7
- STRING:   A5WHX7
- GeneID:   5205643
- GenomeReviews:   CP000713_GR
- KEGG:   prw:PsycPRwf_2328
- eggNOG:   COG0494
- HOGENOM:   HBG302451
- OMA:   GQKQIWY
- ProtClustDB:   PRK00714
- BioCyc:   PSP56811:PSYCPRWF_2328-MONOMER
- HAMAP:   MF_00298
- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR022927
- Gene3D:   G3DSA:3.90.79.10
- PRINTS:   PR00502

Pfam domain/function: PF00293 NUDIX; SSF55811 NUDIX_hydrolase

EC number: 3.6.1.- [C]

Molecular weight: Translated: 20564; Mature: 20564

Theoretical pI: Translated: 8.95; Mature: 8.95

Prosite motif: PS51462 NUDIX; PS00893 NUDIX_BOX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDADGFRANVGIILANTQGQVLWAKRVGHDSWQFPQGGIDEGETPLDAMYRELWEEVGL
CCCCCCCEEEEEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCC
YPRHVQLLAATDNWLRYRLPKRYIRHGQHPLCIGQKQKWFLLKLDEPNTEHIRFDTAKPE
CCHHEEEEEECCCHHHHHCCHHHHHCCCCCEEECCCCCEEEEEECCCCCCEEEEECCCCC
FDHWEWVSYWYPLGQVVHFKRGVYRRALRELARELPLKKELILPETKNHLLQV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCHHHHCCC
>Mature Secondary Structure
MIDADGFRANVGIILANTQGQVLWAKRVGHDSWQFPQGGIDEGETPLDAMYRELWEEVGL
CCCCCCCEEEEEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCC
YPRHVQLLAATDNWLRYRLPKRYIRHGQHPLCIGQKQKWFLLKLDEPNTEHIRFDTAKPE
CCHHEEEEEECCCHHHHHCCHHHHHCCCCCEEECCCCCEEEEEECCCCCCEEEEECCCCC
FDHWEWVSYWYPLGQVVHFKRGVYRRALRELARELPLKKELILPETKNHLLQV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA